This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
QED Bioscience
product type :
antibody
product name :
Anti-Mre11 Antibody
catalog :
56211
quantity :
100 ug
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
12D7

The same clone is also sold as:
reactivity :
human
product information
CATALOG NUMBER :
56211
PRODUCT NAME :
Anti-Mre11 Antibody
NAME+SKU :
Anti-Mre11 Antibody (56211)
PRODUCT _TYPE :
Antibody
DESCRIPTION :
Anti-Mre11 Mouse Monoclonal Antibody
SPECIFICITY SHORT :
Mre11
SPECIES REACTIVITY :
Human
TARGET NAME :
Mre11
UNIPROT :
P49959
LOCATION :
Nucleus , Chromosome, telomere , Chromosome
PROTEIN NAME :
Double-strand break repair protein MRE11
ALTERNATIVE NAMES :
EC 3.1.-.-, Double-strand break repair protein MRE11A, Meiotic recombination 11 homolog 1, MRE11 homolog 1, Meiotic recombination 11 homolog A, MRE11 homolog A
GENE NAME :
MRE11
CLONALITY :
Monoclonal
FORM :
Liquid
CONCENTRATION :
Lot Specific
SIZE 1 :
100 ug
DISTIRBUTOR PRICE :
322.7
SKU SIZE 1 :
56211
APPLICATIONS :
WB, IP
APPLICATION INSTRUCTIONS :
Immunoblotting: Use at 0.5-2ug/ml. A band of ~80kDa is detected. Detection of Mre11 in 30ug of whole cell extracts. Immunofluorescence: use at 1-5ug/ml. Detection of Mre11 in HeLa cells fixed in 4% paraformaldehyde for 15 minutes. These are recommended concentrations. Endusers should determine optimal concentrations for their applications.
HOST :
Mouse
FORMAT :
Purified
ISOTYPE :
IgG1
CLONE ID :
12D7
IMMUNOGEN :
GST fusion protein corresponding to aa 182-582 of Mre11.
RESEARCH AREA :
Cancer research
FORMULATION :
PBS, pH 7.4.
BUFFER :
Phosphate Buffered Saline
BUFFER PH :
pH 7.4
FUNCTION :
Component of the MRN complex, which plays a central role in double-strand break (DSB) repair, DNA rPubMed:10888888, PubMed:11741547, PubMed:15064416, PubMed:29670289, PubMed:30612738, PubMed:9590181, PubMed:9705271}.
STORAGE CONDITION :
This antibody is stable for at least one (1) year at -20C. Avoid multiple freeze- thaw cycles.
SPECIFICITY :
This antibody recognizes human, mouse, and rat Mre11.
Image Name_1 :
qed-bioscience-anti-mre11-antibody-56211-1.jpg
Applications 1 :
WB
Image Name_2 :
qed-bioscience-anti-mre11-antibody-56211-2.jpg
Applications 2 :
Western Blot
Image Name_3 :
qed-bioscience-anti-mre11-antibody-56211-3.jpg
Applications 3 :
WB
Image Name_4 :
qed-bioscience-anti-mre11-antibody-56211-4.jpg
Image Caption_4 :
Mre11 antibody [12D7] detects Mre11 protein at nucleus by immunofluorescent analysis. Sample: HeLa cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: Mre11 stained by Mre11 antibody [12D7] (56211) diluted at 1:200. Blue: Hoechst 33342 staining. Scale bar= 10 um.
Applications 4 :
IF
Image Name_5 :
qed-bioscience-anti-mre11-antibody-56211-5.jpg
Image Caption_5 :
Various whole cell extracts (30 ug) were separated by 7.5% SDS-PAGE, and the membrane was blotted with Mre11 antibody [12D7] (56211) diluted at 1:500. The HRP-conjugated anti-mouset IgG antibody was used to detect the primary antibody.
Applications 5 :
WB
Image Name_6 :
qed-bioscience-anti-mre11-antibody-56211-6.jpg
Image Caption_6 :
Mre11 antibody [12D7] detects Mre11 protein at nucleus by immunohistochemical analysis (Autostainer Formulated). Sample: Paraffin-embedded human colon cancer. Mre11 stained by Mre11 antibody [12D7] (56211) diluted at 1:300. Antigen Retrieval: EDTA buffer, 20 min
Applications 6 :
IHC
company information
QED Bioscience
10919 Technology Place, Suite C San Diego, CA 92127
info@qedbio.com
http://www.qedbio.com
800-929-2114 858-675-2405
headquarters: United States