This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
QED Bioscience
product type :
antibody
product name :
Anti-Id3 Antibody
catalog :
56209
quantity :
100 ug
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
2B11

The same clone is also sold as:
reactivity :
human, mouse
product information
CATALOG NUMBER :
56209
PRODUCT NAME :
Anti-Id3 Antibody
NAME+SKU :
Anti-Id3 Antibody (56209)
PRODUCT _TYPE :
Antibody
DESCRIPTION :
Anti-Id3 Mouse Monoclonal Antibody
SPECIFICITY SHORT :
Id3
SPECIES REACTIVITY :
Human, mouse
TARGET NAME :
Id3
UNIPROT :
Q02535
LOCATION :
Nucleus.
PROTEIN NAME :
DNA-binding protein inhibitor ID-3
ALTERNATIVE NAMES :
Class B basic helix-loop-helix protein 25, bHLHb25, Helix-loop-helix protein HEIR-1, ID-like protein inhibitor HLH 1R21, Inhibitor of DNA binding 3, Inhibitor of differentiation 3
GENE NAME :
ID3
CLONALITY :
Monoclonal
FORM :
Liquid
CONCENTRATION :
Lot Specific
SIZE 1 :
100 ug
DISTIRBUTOR PRICE :
322.7
SKU SIZE 1 :
56209
APPLICATIONS :
WB, IP
APPLICATION INSTRUCTIONS :
Immunoblotting and Immuno- precipitation: use at 1-5 ug/ml. Positive controls: Id3 transfected Sol8 muscles cells and recombinant fusion protein.
HOST :
Mouse
FORMAT :
Purified
ISOTYPE :
IgG1
CLONE ID :
2B11
IMMUNOGEN :
Mouse Id3 gst-fusion protein (aa 1-119) expressed in E. coli.
RESEARCH AREA :
Neuroscience
FORMULATION :
10 mM PBS, pH 7.4.
BUFFER :
Phosphate Buffered Saline
BUFFER PH :
pH 7.4
TARGET BACKGROUND :
Id3 is a 14 kD protein and a member of the Id family of helix-loop-helix (HLH) proteins. Id proteins are believed to be dominant negative regulators of HLH involved in cell differentiation and implicated in the control of cell growth, cellular differentiation, apoptosis, and carcinogenesis.
FUNCTION :
Transcriptional regulator (lacking a basic DNA binding domain) which negatively regulates the basic helix-loop-helix (bHLH) transcription factors by forming heterodimers and inhibiting their DNA binding and transcriptional activity. Implicated in regulating a variety of cellular processes, including cellular growth, senescence, differentiation, apoptosis, angiogenesis, and neoplastic transformation. Involved in myogenesis by inhibiting skeletal muscle and cardiac myocyte differentiation and promoting muscle precursor cells proliferation. Inhibits the binding of E2A-containing protein complexes to muscle creatine kinase E-box enhancer. Regulates the circadian clock by repressing the transcriptional activator activity of the CLOCK-ARNTL/BMAL1 heterodimer. {PubMed:8437843}.
DILUTION INSTRUCTIONS :
Dilute in PBS or medium which is identical to that used in the assay system.
STORAGE CONDITION :
This antibody is stable for at least one (1) year at -20C. Avoid multiple freeze- thaw cycles.
SPECIFICITY :
This antibody recognizes human and mouse Id3.
Image Name_1 :
qed-bioscience-anti-id3-antibody-56209-1.jpg
Applications 1 :
IF
Image Name_2 :
qed-bioscience-anti-id3-antibody-56209-2.jpg
Applications 2 :
WB
company information
QED Bioscience
10919 Technology Place, Suite C San Diego, CA 92127
info@qedbio.com
http://www.qedbio.com
800-929-2114 858-675-2405
headquarters: United States