Anti-S100 alpha/beta Antibody | QED Bioscience 56205 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

QED Bioscience

product type :

antibody

product name :

Anti-S100 alpha/beta Antibody

catalog :

56205

quantity :

100 ug

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

4B3

The same clone is also sold as:

Santa Cruz Biotechnology: sc-52205

reactivity :

human

product information

CATALOG NUMBER :

56205

PRODUCT NAME :

Anti-S100 alpha/beta Antibody

NAME+SKU :

Anti-S100 alpha/beta Antibody (56205)

PRODUCT _TYPE :

Antibody

DESCRIPTION :

Anti-S-100 Mouse Monoclonal Antibody

SPECIFICITY SHORT :

S-100

SPECIES REACTIVITY :

Human

TARGET NAME :

S100 alpha/beta

UNIPROT :

P23297

LOCATION :

Cytoplasm , Sarcoplasmic reticulum , Mitochondrion

PROTEIN NAME :

Protein S100-A1

ALTERNATIVE NAMES :

S-100 protein alpha chain, S-100 protein subunit alpha, S100 calcium-binding protein A1

GENE NAME :

S100A1

CLONALITY :

Monoclonal

FORM :

Liquid

CONCENTRATION :

Lot Specific

SIZE 1 :

100 ug

DISTIRBUTOR PRICE :

229.6

SKU SIZE 1 :

56205

APPLICATIONS :

WB, ELISA, AP

APPLICATION INSTRUCTIONS :

These antibodies may be used in ELISA and Western blot (human brain): 56203, 56204, and 56206 may be used to affinity-purify S-100. Recommended pairs for sandwich ELISA: Capture Detect 56203 56204 56206 56204

HOST :

Mouse

FORMAT :

Purified

PURIFICATION :

Purified by immunoaffinity chromatography

ISOTYPE :

IgG2a

CLONE ID :

4B3

IMMUNOGEN :

Purified S-100 protein from human brain.

RESEARCH AREA :

Neuroscience

FORMULATION :

PBS, pH 7.4, 0.09% sodium azide

BUFFER :

Phosphate Buffered Saline

BUFFER PH :

pH 7.4

BUFFER ANTI-MICROBIAL :

0.09% Sodium Azide

FUNCTION :

Small calcium binding protein that plays important roles in several biological processes such as Ca(2+) homeostasis, chondrocyte biology and cardiomyocyte regulation (PubMed:12804600). In response to an increase in intracellular Ca(2+) levels, binds calcium which triggers conformational changes (PubMed:23351007). These changes allow interactions with specific target proteins and modulate their activity (PubMed:22399290). Regulates a network in cardiomyocytes controlling sarcoplasmic reticulum Ca(2+) cycling and mitochondrial function through interaction with the ryanodine receptors RYR1 and RYR2, sarcoplasmic reticulum Ca(2+)-ATPase/ATP2A2 and mitochondrial F1-ATPase (PubMed:12804600). Facilitates diastolic Ca(2+) dissociation and myofilament mechanics in order to improve relaxation during diastole (PubMed:11717446). {PubMed:11717446, PubMed:12804600, PubMed:22399290, PubMed:23351007}.

DILUTION INSTRUCTIONS :

Dilute in PBS or medium that is identical to that used in the assay system.

STORAGE CONDITION :

These antibodies are stable for at least one (1) year at -20C to -70C. Avoid multiple freeze-thaw cycles.

SPECIFICITY :

56203, 56204, and 56205 recognize S-100alphabeta and S-100 betabeta. 56206 recognizes S-100alphabeta.

Image Name_1 :

qed-bioscience-anti-s100a1-antibody-56205-1.jpg

Applications 1 :