Anti-Estrogen Receptor-a (Phospho-Ser106) Antibody | QED Bioscience 43071 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

QED Bioscience

product type :

antibody

product name :

Anti-Estrogen Receptor-a (Phospho-Ser106) Antibody

catalog :

43071

quantity :

100 ul

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

product information

CATALOG NUMBER :

43071

PRODUCT NAME :

Anti-Estrogen Receptor-a (Phospho-Ser106) Antibody

NAME+SKU :

Anti-Estrogen Receptor-a (Phospho-Ser106) Antibody (43071)

PRODUCT _TYPE :

Antibody

DESCRIPTION :

Anti-Estrogen Receptor-a (Phospho-Ser106) Rabbit Polyclonal Antibody

SPECIFICITY SHORT :

Estrogen Receptor-a (Phospho-Ser106)

SPECIES REACTIVITY :

Human, mouse, rat

TARGET NAME :

Estrogen Receptor-a (Phospho-Ser106)

TARGET ANTIGEN MODIFICATION :

Phospho-ser106

UNIPROT :

G1E6Z3

PROTEIN NAME :

Estrogen receptor a

GENE NAME :

Era

CLONALITY :

Polyclonal

FORM :

Liquid

CONCENTRATION :

1.0 mg/mL

SIZE 1 :

100 ul

DISTIRBUTOR PRICE :

241.5

SKU SIZE 1 :

43071

APPLICATIONS :

WB, IHC, IF

APPLICATION INSTRUCTIONS :

Immunoblotting: use at dilution of 1:500-1:1,000. A band of ~66kDa is detected. Immunofluorescence: use at dilution of 1:100-1:200. Immunohistochemistry: use at dilution of 1:50-1:100. These are recommended working dilutions. Enduser should determine optimal dilutions for their applications.

HOST :

Rabbit

FORMAT :

Purified

PURIFICATION :

Purified by immunoaffinity chromatography

IMMUNOGEN :

Peptide sequence that includes phosphorylation site of serine 106 (S-P-S(p)-P-L) derived from human estrogen receptor-alpha and conjugated to KLH.

RESEARCH AREA :

Phosphospecific Antibodies

FORMULATION :

PBS (without Mg2 and Ca2 ), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

BUFFER :

Phosphate Buffered Saline

BUFFER PH :

pH 7.4

BUFFER ANTI-MICROBIAL :

0.02% Sodium Azide

BUFFER CRYOPRESERVATIVE :

50% Glycerol

TARGET BACKGROUND :

Estrogen receptor alpha (ERalpha), also known as NR3A1 (nuclear receptor subfamily 3, group A, member 1), is one of two main types of estrogen receptor, a nuclear receptor that is activated by estrogen. In humans, ERalpha is encoded by the gene ESR1 (Estrogen Receptor 1). Estrogen receptor (ER) is a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. Alternative splicing results in several ESR1 mRNA transcripts, which differ primarily in their 5-prime untranslated regions. The translated receptors show less variability.

DILUTION INSTRUCTIONS :

Dilute in PBS or medium that is identical to that used in the assay system.

STORAGE CONDITION :

This antibody is stable for at least one (1) year at -20C. Can be stored at 4C for short-term.

SPECIFICITY :

This antibody detects endogenous human, mouse, and rat estrogen receptor-alpha only when phosphorylated at serine 106.Accession no.: P03372, NP_000116.2