Anti-CA-125/MUC16 Antibody | QED Bioscience 3330 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

QED Bioscience

product type :

antibody

product name :

Anti-CA-125/MUC16 Antibody

catalog :

3330

quantity :

100 ug

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

X75

The same clone is also sold as:

Bio-Rad: MCA2877
Invitrogen: MA1-24601, MA1-90039
Novus Biologicals: NB600-1468
MyBioSource: MBS214597

reactivity :

human

product information

CATALOG NUMBER :

3330

PRODUCT NAME :

Anti-CA-125/MUC16 Antibody

NAME+SKU :

Anti-CA-125/MUC16 Antibody (3330)

PRODUCT _TYPE :

Antibody

DESCRIPTION :

Anti-CA-125 Mouse Monoclonal Antibody

SPECIFICITY SHORT :

CA-125

SPECIES REACTIVITY :

Human

TARGET NAME :

CA-125/MUC16

UNIPROT :

Q8WXI7

LOCATION :

Cell membrane; Single-pass type I membrane protein. Secreted, extracellular space. Note=May be liberated into the extracellular space following the phosphorylation of the intracellular C-terminus which induces the proteolytic cleavage and liberation of the extracellular domain.

PROTEIN NAME :

Mucin-16

ALTERNATIVE NAMES :

MUC-16, Ovarian cancer-related tumor marker CA125, CA-125, Ovarian carcinoma antigen CA125

GENE NAME :

MUC16

ACCESSION NUMBER :

NP_078966

CLONALITY :

Monoclonal

FORM :

Liquid

CONCENTRATION :

Lot Specific

SIZE 1 :

100 ug

DISTIRBUTOR PRICE :

200.2

SKU SIZE 1 :

3330

APPLICATIONS :

IHC, FACS

APPLICATION INSTRUCTIONS :

These antibodies may be used in ELISA and Western blotting to detect CA-125. Positive control: OVCAR3 ovarian adenocarcinoma cells. Suggested pairs for sandwich ELISA:

HOST :

Mouse

FORMAT :

Purified

PURIFICATION :

Purified by immunoaffinity chromatography

ISOTYPE :

IgG1

CLONE ID :

X75

IMMUNOGEN :

CA-125 purified from ovarian carcinoma cells.

RESEARCH AREA :

Cancer Research

FORMULATION :

10mM Tris buffer, pH 7.5, 0.15M NaCL, 0.05% sodium azide

BUFFER :

Tris Buffer

BUFFER PH :

pH 7.5

BUFFER ANTI-MICROBIAL :

0.05% Sodium Azide

TARGET BACKGROUND :

CA-125 (cancer antigen 125, carcinoma antigen 125, or carbohydrate antigen 125) also known as mucin 16 or MUC16 is encoded by the MUC16 gene in humans. MUC16 is a member of the mucin family of glycoproteins. CA-125 is most consistently elevated in epithelial ovarian cancer, but can be expressed in a number of gynecologic (endometrial, fallopian tube) and non- gynecologic (pancreatic, breast, colon and lung) cancers. It may also be elevated in cases of benign abnormalities such as endometriosis.

FUNCTION :

Thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces. {ECO:0000250}.

DILUTION INSTRUCTIONS :

Dilute in PBS or medium that is identical to that used in the assay system.

STORAGE CONDITION :

This antibody is stable for at least one (1) year at -70C. Avoid multiple freeze-thaw cycles.

SPECIFICITY :

#3330 and #3345 epitope group B (ISOBM* classification). #3346 epitope group A (ISOBM* classification)*International Society of Oncology and Biomarkers