Anti-Fibroblast Growth Factor 13 (FGF13) Antibody | QED Bioscience 30109 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

QED Bioscience

product type :

antibody

product name :

Anti-Fibroblast Growth Factor 13 (FGF13) Antibody

catalog :

30109

quantity :

100 ug

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

S235-22

The same clone is also sold as:

OriGene: AM60047PU-N
Novus Biologicals: NBP2-42178
Rockland Immunochemicals: 200-352-W62, 200-367-W62, 200-308-W62, 200-360-W62, 200-303-W62, 200-302-W62, 200-305-W62, 200-357-W62, 200-361-W62, 200-365-W62, 200-355-W62, 200-306-W62, 200-301-W62, 200-326-W62, 200-363-W62, 200-366-W62, 200-358-W62

reactivity :

human, mouse, rat

product information

CATALOG NUMBER :

30109

PRODUCT NAME :

Anti-Fibroblast Growth Factor 13 (FGF13) Antibody

NAME+SKU :

Anti-Fibroblast Growth Factor 13 (FGF13) Antibody (30109)

PRODUCT _TYPE :

Antibody

DESCRIPTION :

Anti-Fibroblast Growth Factor 13 (FGF13) Mouse Monoclonal Antibody

SPECIFICITY SHORT :

Fibroblast Growth Factor 13 (FGF13)

SPECIES REACTIVITY :

Human, mouse, rat

TARGET NAME :

Fibroblast Growth Factor 13 (FGF13)

UNIPROT :

Q92913

LOCATION :

[Isoform 1]: Nucleus , Nucleus , Nucleus , Nucleus , Nucleus , Cell projection, growth cone , Cell projection, dendrite , Cell membrane, sarcolemma , Cytoplasm

PROTEIN NAME :

Fibroblast growth factor 13

ALTERNATIVE NAMES :

FGF-13, Fibroblast growth factor homologous factor 2, FHF-2

GENE NAME :

FGF13

CLONALITY :

Monoclonal

FORM :

Liquid

CONCENTRATION :

1.0 mg/mL

SIZE 1 :

100 ug

DISTIRBUTOR PRICE :

305.2

SKU SIZE 1 :

30109

APPLICATIONS :

WB, IF

APPLICATION INSTRUCTIONS :

Immunoblotting: use at 1-5ug/ml. A band of ~30kDa is detected. Immunofluorescence: use at 10ug/ml. These are recommended concentrations. Endusers should determine optimal concentrations for their application.

HOST :

Mouse

FORMAT :

Purified

PURIFICATION :

Purified by Protein G affinity chromatography.

ISOTYPE :

IgG2b

CLONE ID :

S235-22

IMMUNOGEN :

Fusion protein corresponding to aa 2-18 (AAAIASSLIRQKRQARE) of human FGF13. This sequence is 100

RESEARCH AREA :

Growth Factors, Cytokines, Receptors

FORMULATION :

PBS, pH 7.4, 0.1% sodium azide, 50% glycerol.

BUFFER :

Phosphate Buffered Saline

BUFFER PH :

pH 7.4

BUFFER ANTI-MICROBIAL :

0.1% Sodium Azide

BUFFER CRYOPRESERVATIVE :

50% Glycerol

TARGET BACKGROUND :

FGF13 (also known as FGF2 and FHF2) is a member of the fibroblast growth factor family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth, and invasion. The FGF13 gene is located in a region on chromosome X that is associated with Borjeson-Forssman-Lehmann syndrome (BFLS), making it a candidate gene for familial cases of BFLS and other syndromal and nonspecific forms of X-linked mental retardation mapping to this region. Alternative splicing of this gene at the 5â€² end results in several transcript variants encoding different isoforms with different N-termini.

FUNCTION :

Microtubule-binding protein which directly binds tubulin and is involved in both polymerization and stabilization of microtubules (By similarity). Through its action on microtubules, may participate in the refinement of axons by negatively regulating axonal and leading processes branching (By similarity). Plays a crucial role in neuron polarization and migration in the cerebral cortex and the hippocampus (By similarity). Regulates voltage-gated sodium channels transport and function (PubMed:15282281, PubMed:33245860). May also play a role in MAPK signaling (By similarity). Required for the development of axonal initial segment-targeting inhibitory GABAergic synapses made by chandelier neurons (By similarity). {UniProtKB:P70377, PubMed:15282281, PubMed:33245860}.

DILUTION INSTRUCTIONS :

Dilute in PBS or medium that is identical to that used in the assay system.

STORAGE CONDITION :

This product is stable for at least one (1)year at -20 C to -70 C. Store product in appropriate aliquots to avoid multiple freeze-thaw cycles.

SPECIFICITY :

This antibody recognizes human, mouse, and rat FGF13.

Image Name_1 :

qed-bioscience-anti-fibroblast-growth-factor-13-fgf13-antibody-30109-1.png

Applications 1 :

ICC

Image Name_2 :

qed-bioscience-anti-fibroblast-growth-factor-13-fgf13-antibody-30109-2.png

Applications 2 :

ICC

Image Name_3 :

qed-bioscience-anti-fibroblast-growth-factor-13-fgf13-antibody-30109-3.png

Applications 3 :

Western Blot