This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
QED Bioscience
product type :
antibody
product name :
Anti-MMP 9 Antibody
catalog :
29022
quantity :
100 ug
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
reactivity :
human, mouse, rat
product information
CATALOG NUMBER :
29022
PRODUCT NAME :
Anti-MMP 9 Antibody
NAME+SKU :
Anti-MMP 9 Antibody (29022)
PRODUCT _TYPE :
Antibody
DESCRIPTION :
Anti-MMP9 Metalloproteinase Mouse Monoclonal Antibody
SPECIFICITY SHORT :
MMP9 Metalloproteinase
SPECIES REACTIVITY :
Human, mouse, rat
TARGET NAME :
MMP 9
UNIPROT :
P50282
LOCATION :
Secreted, extracellular space, extracellular matrix
PROTEIN NAME :
Matrix metalloproteinase-9
ALTERNATIVE NAMES :
MMP-9, EC 3.4.24.35, 92 kDa gelatinase, 92 kDa type IV collagenase, Gelatinase B, GELB
GENE NAME :
Mmp9
CLONALITY :
Monoclonal
FORM :
Liquid
CONCENTRATION :
1.0 mg/mL
SIZE 1 :
100 ug
DISTIRBUTOR PRICE :
305.2
SKU SIZE 1 :
29022
APPLICATIONS :
WB, IHC
APPLICATION INSTRUCTIONS :
Immunoblotting: use at 1-2ug/ml. Bands of ~92 and 82kDa (proenzyme and active enzyme) are detected.
Immunohistochemistry: use at 1-5ug/ml.
These are recommended concentrations. Enduser should determine optimal concentrations for their applications.
Positive control: rat brain lysate.
HOST :
Mouse
FORMAT :
Purified
PURIFICATION :
Purified by immunoaffinity chromatography
ISOTYPE :
IgG2a
CLONE ID :
S51-82
IMMUNOGEN :
Fusion protein corresponding to aa 1-708 (full-length) of rat MMP 9 (accession no. NP_112317).
RESEARCH AREA :
Matrix/Metalloproteins
FORMULATION :
PBS, pH 7.4, 50% glycerol, 0.09% sodium azide.
Purified by Protein G affinity chromatography.
BUFFER :
Phosphate Buffered Saline
BUFFER PH :
pH 7.4
BUFFER ANTI-MICROBIAL :
0.09% Sodium Azide
BUFFER CRYOPRESERVATIVE :
50% Glycerol
TARGET BACKGROUND :
MMP 9 is involved in the breakdown of extracellular matrix in embryonic development, reproduction, wound healing, and tissue remodeling as well as in disease processes such as arthiritis and metastasis. Once synthesized, MMPs exist as latent proenzymes. Maximum MMP activity requires proteolytic cleavage of the proenzyme to generate active MMP by releasing the inhibitory propeptide domain from the full-length protein.
FUNCTION :
Matrix metalloproteinase that plays an essential role in local proteolysis of the extracellular matrix and in leukocyte migration (By similarity). Could play a role in bone osteoclastic resorption (By similarity). Cleaves KiSS1 at a Gly- -Leu bond (By similarity). Cleaves NINJ1 to generate the Secreted ninjurin-1 form (By similarity). Cleaves type IV and type V collagen into large C-terminal three quarter fragments and shorter N-terminal one quarter fragments. Degrades fibronectin but not laminin or Pz-peptide (By similarity). {UniProtKB:P14780, UniProtKB:P41245}.
DILUTION INSTRUCTIONS :
Dilute in PBS or medium which is identical to that used in the assay system.
STORAGE CONDITION :
This antibody is stable for at least one (1) year at -20C to -70C. Store antibody in appropriate aliquots to avoid multiple freeze-thaw cycles.
SPECIFICITY :
This antibody recognizes human, mouse, and rat MMP 9.
Image Name_1 :
qed-bioscience-anti-mmp-9-antibody-29022-1.png
Applications 1 :
ICC
Image Name_2 :
qed-bioscience-anti-mmp-9-antibody-29022-2.png
Applications 2 :
ICC
Image Name_3 :
qed-bioscience-anti-mmp-9-antibody-29022-3.png
Applications 3 :
Western Blot
company information
QED Bioscience
10919 Technology Place, Suite C San Diego, CA 92127
info@qedbio.com
http://www.qedbio.com800-929-2114 858-675-2405
headquarters: United States
questions and comments