Anti-Factor XII Light Chain Antibody | QED Bioscience 19802 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

QED Bioscience

product type :

antibody

product name :

Anti-Factor XII Light Chain Antibody

catalog :

19802

quantity :

250 ug

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

C6B7

The same clone is also sold as:

Santa Cruz Biotechnology: sc-59519
Invitrogen: MA1-26322, MA1-10829

reactivity :

human

product information

CATALOG NUMBER :

19802

PRODUCT NAME :

Anti-Factor XII Light Chain Antibody

NAME+SKU :

Anti-Factor XII Light Chain Antibody (19802)

PRODUCT _TYPE :

Antibody

DESCRIPTION :

Anti-Factor XII Light Chain Mouse Monoclonal Antibody

SPECIFICITY SHORT :

Factor XII Light Chain

SPECIES REACTIVITY :

Human

TARGET NAME :

Factor XII Light Chain

UNIPROT :

P00748

LOCATION :

Secreted.

PROTEIN NAME :

Coagulation factor XII

ALTERNATIVE NAMES :

EC 3.4.21.38, Hageman factor, HAF [Cleaved into: Coagulation factor XIIa heavy chain; Beta-factor XIIa part 1; Coagulation factor XIIa light chain

GENE NAME :

F12

CLONALITY :

Monoclonal

FORM :

Liquid

CONCENTRATION :

Lot Specific

SIZE 1 :

250 ug

DISTIRBUTOR PRICE :

365.4

SKU SIZE 1 :

19802

APPLICATIONS :

ELISA, coagulation assays

APPLICATION INSTRUCTIONS :

This antibody may be used in ELISA to detect/quantitate Factor XII and in coagulation assays. Other applications are under investigation.

HOST :

Mouse

FORMAT :

Purified

PURIFICATION :

Purified by Protein G affinity chromatography.

ISOTYPE :

IgG1

CLONE ID :

C6B7

IMMUNOGEN :

Purified human Factor XII.

RESEARCH AREA :

Coagulation factors

FORMULATION :

PBS, pH 7.4.

BUFFER :

Phosphate Buffered Saline

BUFFER PH :

pH 7.4

FUNCTION :

Factor XII is a serum glycoprotein that participates in the initiation of blood coagulation, fibrinolysis, and the generation of bradykinin and angiotensin. Prekallikrein is cleaved by factor XII to form kallikrein, which then cleaves factor XII first to alpha-factor XIIa and then trypsin cleaves it to beta-factor XIIa. Alpha-factor XIIa activates factor XI to factor XIa. {PubMed:21304106}.

DILUTION INSTRUCTIONS :

Dilute in PBS or medium that is identical to that used in the assay system.

STORAGE CONDITION :

These antibodies are stable for at least one (1) year at -20C to -70C. Store product in appropriate aliquots to avoid multiple freeze-thaw cycles.

SPECIFICITY :

Purified human Factor XII.