Anti-Factor XII Heavy Chain Antibody | QED Bioscience 19801 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

QED Bioscience

product type :

antibody

product name :

Anti-Factor XII Heavy Chain Antibody

catalog :

19801

quantity :

250 ug

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

B7C9

The same clone is also sold as:

Santa Cruz Biotechnology: sc-59518 AC, sc-59518 HRP, sc-59518
Invitrogen: MA1-10828, MA1-21551

reactivity :

human

product information

CATALOG NUMBER :

19801

PRODUCT NAME :

Anti-Factor XII Heavy Chain Antibody

NAME+SKU :

Anti-Factor XII Heavy Chain Antibody (19801)

PRODUCT _TYPE :

Antibody

DESCRIPTION :

Anti-Factor XII Heavy Chain Mouse Monoclonal Antibody

SPECIFICITY SHORT :

Factor XII Heavy Chain

SPECIES REACTIVITY :

Human

TARGET NAME :

Factor XII Heavy Chain

UNIPROT :

P00748

LOCATION :

Secreted.

PROTEIN NAME :

Coagulation factor XII

ALTERNATIVE NAMES :

EC 3.4.21.38, Hageman factor, HAF [Cleaved into: Coagulation factor XIIa heavy chain; Beta-factor XIIa part 1; Coagulation factor XIIa light chain

GENE NAME :

F12

CLONALITY :

Monoclonal

FORM :

Liquid

CONCENTRATION :

Lot Specific

SIZE 1 :

250 ug

DISTIRBUTOR PRICE :

365.4

SKU SIZE 1 :

19801

APPLICATIONS :

WB, ELISA, AP, coagulation assays

APPLICATION INSTRUCTIONS :

This antibody may be used in ELISA, Western blot, coagulation assays and for immunopurification of Factor XII.

HOST :

Mouse

FORMAT :

Purified

PURIFICATION :

Purified by Protein G affinity chromatography.

ISOTYPE :

IgG1

CLONE ID :

B7C9

IMMUNOGEN :

Purified human Factor XII.

RESEARCH AREA :

Coagulation factors

FORMULATION :

PBS, pH 7.4.

BUFFER :

Phosphate Buffered Saline

BUFFER PH :

pH 7.4

FUNCTION :

Factor XII is a serum glycoprotein that participates in the initiation of blood coagulation, fibrinolysis, and the generation of bradykinin and angiotensin. Prekallikrein is cleaved by factor XII to form kallikrein, which then cleaves factor XII first to alpha-factor XIIa and then trypsin cleaves it to beta-factor XIIa. Alpha-factor XIIa activates factor XI to factor XIa. {PubMed:21304106}.

DILUTION INSTRUCTIONS :

Dilute in PBS or medium that is identical to that used in the assay system.

STORAGE CONDITION :

These antibodies are stable for at least one (1) year at -20C to -70C. Store product in appropriate aliquots to avoid multiple freeze-thaw cycles.

SPECIFICITY :

Purified human Factor XII.