Anti-TrpV3 Cation Channel Antibody | QED Bioscience 11527 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

QED Bioscience

product type :

antibody

product name :

Anti-TrpV3 Cation Channel Antibody

catalog :

11527

quantity :

100 ug

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

S15-39

The same clone is also sold as:

OriGene: TA326599
Rockland Immunochemicals: 200-301-G59

reactivity :

human, mouse, rat

product information

CATALOG NUMBER :

11527

PRODUCT NAME :

Anti-TrpV3 Cation Channel Antibody

NAME+SKU :

Anti-TrpV3 Cation Channel Antibody (11527)

PRODUCT _TYPE :

Antibody

DESCRIPTION :

Anti-TrpV3 Cation Channel Mouse Monoclonal Antibody

SPECIFICITY SHORT :

TrpV3 Cation Channel

SPECIES REACTIVITY :

Human, mouse, rat

TARGET NAME :

TrpV3 Cation Channel

UNIPROT :

Q4QYD9

PROTEIN NAME :

Heat sensitive channel TRPV3

ACCESSION NUMBER :

NP_001020928

CLONALITY :

Monoclonal

FORM :

Liquid

CONCENTRATION :

Lot Specific

SIZE 1 :

100 ug

DISTIRBUTOR PRICE :

305.2

SKU SIZE 1 :

11527

APPLICATIONS :

WB, IHC, ICC, IF

APPLICATION INSTRUCTIONS :

Immunoblotting: use at 1ug/ml. A band of ~70kDa is detected. Immunohistochemistry and Immunocytochemistry: use at 0.1-1ug/ml Immunofluorescence: use at 1-10ug/ml These are recommended concentrations. User should determine optimal concentrations for their application. Positive control: Lysate of COS-1 cells transiently-transfected with TrpV3.

HOST :

Mouse

FORMAT :

Purified

PURIFICATION :

Purified by immunoaffinity chromatography

ISOTYPE :

IgG1

CLONE ID :

S15-39

IMMUNOGEN :

Synthetic peptide corresponding to aa 458-474 (cytoplasmic C-terminus) of rat TrpV3 (accession no. NP_001020928). This sequence is 77

RESEARCH AREA :

Ion Channels

FORMULATION :

PBS, pH 7.4; 50% glycerol, 0.09% sodium azide.

BUFFER :

Phosphate Buffered Saline

BUFFER PH :

pH 7.4

BUFFER ANTI-MICROBIAL :

0.09% Sodium Azide

BUFFER CRYOPRESERVATIVE :

50% Glycerol

TARGET BACKGROUND :

Ion channels are integral membrane proteins that help establish and control the small voltage gradient across the plasma membrane of living cells by allowing the flow of ions down their electrochemical gradient. TrpV3 is in a family of non- selective cation channels that function in a variety of processes including temperature sensation and vaso-regulation. The thermosensitive members of this family are expressed in sensory neurons that terminate in the skin and is activated at temperatures between 22-40oC. TrpV3 might associate with TrpV1 to form heteromeric channels.

DILUTION INSTRUCTIONS :

Dilute in PBS or medium which is identical to that used in the assay system.

STORAGE CONDITION :

This antibody is stable for at least one (1) year at 2-8C. Shield from light.

SPECIFICITY :

This antibody recognizes human, mouse, and rat TrpV3.

Image Name_1 :

qed-bioscience-anti-trpv3-cation-channel-antibody-11527-1.png

Applications 1 :

ICC

Image Name_2 :

qed-bioscience-anti-trpv3-cation-channel-antibody-11527-2.png

Applications 2 :

ICC

Image Name_3 :

qed-bioscience-anti-trpv3-cation-channel-antibody-11527-3.png

Applications 3 :

IHC

Image Name_4 :

qed-bioscience-anti-trpv3-cation-channel-antibody-11527-4.png

Image Caption_4 :

Western Blot analysis of Rat brain membrane lysate showing detection of TrpV3 protein using Mouse Anti-TrpV3 Monoclonal Antibody, Clone S15-39 (11527). Load: 15 µg. Block: 1.5% BSA for 30 minutes at RT. Primary Antibody: Mouse Anti-TrpV3 Monoclonal Antibody (11527) at 1:1000 for 2 hours at RT. Secondary Antibody: Sheep Anti-Mouse IgG: HRP for 1 hour at RT.

Applications 4 :

Western Blot