Anti-tsp23 Antibody | QED Bioscience 11137 product information

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product summary

company name :

QED Bioscience

product type :

antibody

product name :

Anti-tsp23 Antibody

catalog :

11137

quantity :

100 ug

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

Tsp232A

reactivity :

human, mouse

product information

CATALOG NUMBER :

11137

PRODUCT NAME :

Anti-tsp23 Antibody

NAME+SKU :

Anti-tsp23 Antibody (11137)

PRODUCT _TYPE :

Antibody

DESCRIPTION :

Anti-tsp23 Mouse Monoclonal Antibody

SPECIFICITY SHORT :

tsp23

SPECIES REACTIVITY :

Human, mouse

TARGET NAME :

tsp23

UNIPROT :

B9A003

PROTEIN NAME :

Putative protein PTGES3L

GENE NAME :

PTGES3L

ACCESSION NUMBER :

NP_001136126.1

CLONALITY :

Monoclonal

FORM :

Liquid

CONCENTRATION :

1.0 mg/mL

SIZE 1 :

100 ug

DISTIRBUTOR PRICE :

298.9

SKU SIZE 1 :

11137

APPLICATIONS :

APPLICATION INSTRUCTIONS :

Immunoblotting: use at 1ug/ml. A band of ~19kDa is detected. These are recommended concentrations; enduser should determine optimal concentrations for their applications. Positive control: Lysate of HeLa cells transiently transfected with Tsp23.

HOST :

Mouse

FORMAT :

Purified

PURIFICATION :

Purified by immunoaffinity chromatography

ISOTYPE :

IgG1

CLONE ID :

tsp232A

IMMUNOGEN :

Recombinant tsp23

RESEARCH AREA :

Heat Shock & Stress Proteins

FORMULATION :

PBS, pH 7.4, 50% glycerol, 0.09% sodium azide. Purified by Protein G affinity chromatography.

BUFFER :

Phosphate Buffered Saline

BUFFER PH :

pH 7.4

BUFFER ANTI-MICROBIAL :

0.09% Sodium Azide

BUFFER CRYOPRESERVATIVE :

50% Glycerol

TARGET BACKGROUND :

tsp23 (transcript similar p23) is a homolog of human p23, a highly conserved ubiquitous protein and a cochaperone for the Hsp90 chaperone system. A small protein (18-25kDa) with a simple structure, p23 is a highly acidic phosphoprotein with an aspartic acid- rich C-terminal domain. Although numerous studies have found p23 associated with other proteins (i.e, Fes tyrosine kinase, heme regulated kinase HRI, Hsf1 transcription factor, aryl hydrocarbon receptor, telomerase, and Hepadnavirus reverse transcriptase), the functional significance of p23 remains to be clearly defined. It appears to be involved in ATP-mediated Hsp90 binding of client proteins. A recent study suggests that p23 might be a promising target in leukemic apoptosis. tsp23 is 44% homologous with p23.

DILUTION INSTRUCTIONS :

Dilute in PBS or medium which is identical to that used in the assay system.

STORAGE CONDITION :

This antibody is stable for at least one (1) year at -20C. Avoid repeated freeze- thaw cycles.

SPECIFICITY :

This antibody recognizes human and mouse tsp23. Other species have not been investigated. It does not cross-react with p23.

Image Name_1 :

qed-bioscience-anti-tsp23-antibody-11137-1.png

Applications 1 :

IHC

Image Name_2 :

qed-bioscience-anti-tsp23-antibody-11137-2.png

Applications 2 :

Western Blot