Anti-Hsp22 Antibody | QED Bioscience 11133 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

QED Bioscience

product type :

antibody

product name :

Anti-Hsp22 Antibody

catalog :

11133

quantity :

100 ug

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

3C12.H11

The same clone is also sold as:

Invitrogen: MA5-27706, MA5-45254, MA5-45255, MA5-45256, MA5-45253
Rockland Immunochemicals: 200-301-F53

reactivity :

human, mouse, rat

product information

CATALOG NUMBER :

11133

PRODUCT NAME :

Anti-Hsp22 Antibody

NAME+SKU :

Anti-Hsp22 Antibody (11133)

PRODUCT _TYPE :

Antibody

DESCRIPTION :

Anti-Hsp22 Mouse Monoclonal Antibody

SPECIFICITY SHORT :

Hsp22

SPECIES REACTIVITY :

Human, mouse, rat

TARGET NAME :

Hsp22

UNIPROT :

Q9UJY1,Q9UJY2

PROTEIN NAME :

Heat shock protein beta-8, Equilibrative nucleoside transporter 1

GENE NAME :

HSPB8, SLC29A1

ACCESSION NUMBER :

NP_055180.1, NP_055180.2

CLONALITY :

Monoclonal

FORM :

Liquid

CONCENTRATION :

Lot Specific

SIZE 1 :

100 ug

DISTIRBUTOR PRICE :

242.9

SKU SIZE 1 :

11133

APPLICATIONS :

APPLICATION INSTRUCTIONS :

Immunoblotting: use at 1-10ug/ml. A band of ~22kDa (monomeric) is detected. These are recommended concentrations. User should determine optimal concentrations for their application. Positive control: Whole rat tissue extract.

HOST :

Mouse

FORMAT :

Purified

PURIFICATION :

Purified by Protein G affinity chromatography.

ISOTYPE :

IgG1

CLONE ID :

3C12.H11

IMMUNOGEN :

Host Species: Mouse

RESEARCH AREA :

Heat Shock & Stress Proteins

FORMULATION :

PBS, pH 7.4, 50% glycerol, 0.09% sodium azide.

BUFFER :

Phosphate Buffered Saline

BUFFER PH :

pH 7.4

BUFFER ANTI-MICROBIAL :

0.09% Sodium Azide

BUFFER CRYOPRESERVATIVE :

50% Glycerol

TARGET BACKGROUND :

Hsp22 (HspB8) is a member of the small heat shock protein super-family. Like most other sHsps, Hsp22 is predominantly transcribed in skeletal muscle and heart as well as placenta. It is a monomeric protein which interacts with HspB1. It displays temperature- dependent chaperone activity. Hsp22 has two binding domains (N- and C- terminal) that are specific for different binding partners and has the ability to bind itself and other sHsps. Its chaperone-like activity is important to the function of Hsp22 in various processes including proliferation, apoptosis, and macroautophagy.

DILUTION INSTRUCTIONS :

Dilute in PBS or medium which is identical to that used in the assay system.

STORAGE CONDITION :

This antibody is stable for at least one (1) year at -20C. Avoid repeated freezing and thawing.

SPECIFICITY :

This antibody recognizes human, mouse, and rat Hsp22. It detects endogenous and exogenous Hsp22 in monomeric, dimeric, and tetrameric (weak) forms in Western blots. Exogenous Hsp22 is detected in dimeric form.It does not cross-react with alpha crystallin.