Anti-Hsp40 (Ydj1) Antibody | QED Bioscience 11114 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

QED Bioscience

product type :

antibody

product name :

Anti-Hsp40 (Ydj1) Antibody

catalog :

11114

quantity :

100 ug

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

1G10.H8

The same clone is also sold as:

Rockland Immunochemicals: 200-301-E58
StressMarq Biosciences: SMC-150

reactivity :

Saccharomyces cerevisiae S288C

product information

CATALOG NUMBER :

11114

PRODUCT NAME :

Anti-Hsp40 (Ydj1) Antibody

NAME+SKU :

Anti-Hsp40 (Ydj1) Antibody (11114)

PRODUCT _TYPE :

Antibody

DESCRIPTION :

Anti-HSp40 (Ydj1) Mouse Monoclonal Antibody

SPECIFICITY SHORT :

HSp40 (Ydj1)

SPECIES REACTIVITY :

Yeast

TARGET NAME :

Hsp40 (Ydj1)

UNIPROT :

P25491

LOCATION :

Cytoplasm. Cytoplasm, perinuclear region. Note=Concentrated in a perinuclear ring as well as in the cytoplasm.

PROTEIN NAME :

Mitochondrial protein import protein MAS5

ALTERNATIVE NAMES :

Yeast dnaJ protein 1

GENE NAME :

YDJ1

ACCESSION NUMBER :

NP_014335.1

CLONALITY :

Monoclonal

FORM :

Liquid

CONCENTRATION :

Lot Specific

SIZE 1 :

100 ug

DISTIRBUTOR PRICE :

264.6

SKU SIZE 1 :

11114

APPLICATIONS :

WB, ELISA, IP

APPLICATION INSTRUCTIONS :

Immunoblotting: use at 0.5-1ug/ml. A band of ~40 kDa is detected. User should determine optimal concentrations for their application.

HOST :

Mouse

FORMAT :

Purified

PURIFICATION :

Purified by Protein G affinity chromatography.

ISOTYPE :

IgG1

CLONE ID :

1G10.H8

IMMUNOGEN :

Host Species: Mouse

RESEARCH AREA :

Heat Shock & Stress Proteins

FORMULATION :

PBS, pH 7.4.

BUFFER :

Phosphate Buffered Saline

BUFFER PH :

pH 7.4

TARGET BACKGROUND :

Members of the human Hsp40/DnaJ protein family feature a J domain (named for the bacterial DnaJ protein). The J domain spans the first 75 N- terminal amino acids and is separated from the C-terminus by a glycine- phenylalanine-rech domain. The Hsp40/DnaJ proteins play many different roles in cellular processes such as folding, translocation, degradation, and assembly of multi-protein complexes. Hdj1, the first human Hsp40/DnaJ protein identified, plays an important role in protein translation and folding as well as in regulation of Hsp70 function. Hsp40 stimulates ATPase activity of Hsp70 which in turn causes conformational changes in unfolded proteins.

FUNCTION :

Probably involved in mitochondrial protein import. Is also required for efficient translocation of pre-pro-alpha-factor. Involved in heme regulation of HAP1, as a component of the high-molecular-weight (HMC) complex. {PubMed:11689685}.

DILUTION INSTRUCTIONS :

Dilute in PBS or medium which is identical to that used in the assay system.

STORAGE CONDITION :

This antibody is stable for at least one (1) year at -20C. Avoid repeated freezing and thawing.

SPECIFICITY :

This antibody recognizes yeast Hsp40 (Ydj1). It does not cross-react with human, mouse, or rat Hsp40.