Anti-Hsp40 (Hdj1) Antibody | QED Bioscience 11111 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

QED Bioscience

product type :

antibody

product name :

Anti-Hsp40 (Hdj1) Antibody

catalog :

11111

quantity :

100 ug

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

3B9.E6

The same clone is also sold as:

Invitrogen: MA5-27685, MA5-45176, MA5-45178, MA5-45179, MA5-45177
Novus Biologicals: NBP2-12876-100ug
Rockland Immunochemicals: 200-301-F56
Abcam: ab223607
OriGene: TA326376
StressMarq Biosciences: SMC-145

reactivity :

human, mouse, rat

product information

CATALOG NUMBER :

11111

PRODUCT NAME :

Anti-Hsp40 (Hdj1) Antibody

NAME+SKU :

Anti-Hsp40 (Hdj1) Antibody (11111)

PRODUCT _TYPE :

Antibody

DESCRIPTION :

Anti-Hsp40 Mouse Monoclonal Antibody

SPECIFICITY SHORT :

Hsp40

SPECIES REACTIVITY :

Human, mouse, rat

TARGET NAME :

Hsp40 (Hdj1)

UNIPROT :

P25685

LOCATION :

Cytoplasm , Nucleus , Nucleus, nucleolus

PROTEIN NAME :

DnaJ homolog subfamily B member 1

ALTERNATIVE NAMES :

DnaJ protein homolog 1, Heat shock 40 kDa protein 1, HSP40, Heat shock protein 40, Human DnaJ protein 1, hDj-1

GENE NAME :

DNAJB1

ACCESSION NUMBER :

NP_006136.1

CLONALITY :

Monoclonal

FORM :

Liquid

CONCENTRATION :

Lot Specific

SIZE 1 :

100 ug

DISTIRBUTOR PRICE :

264.6

SKU SIZE 1 :

11111

APPLICATIONS :

WB, ELISA, IHC, IP

APPLICATION INSTRUCTIONS :

Immunoblotting: use at 0.5-1ug/ml. A band of ~40 kDa is detected. ELISA Immunohistochemistry Imunoprecipitation User should determine optimal concentrations for their application. Positive control: HeLa cell lysate.

HOST :

Mouse

FORMAT :

Purified

PURIFICATION :

Purified by Protein G affinity chromatography.

ISOTYPE :

IgG1

CLONE ID :

3B9.E6

IMMUNOGEN :

Host Species: Mouse

RESEARCH AREA :

Heat Shock & Stress Proteins

FORMULATION :

PBS, pH 7.4.

BUFFER :

Phosphate Buffered Saline

BUFFER PH :

pH 7.4

TARGET BACKGROUND :

Members of the human Hsp40/DnaJ protein family feature a J domain (named for the bacterial DnaJ protein). The J domain spans the first 75 N- terminal amino acids and is separated from the C-terminus by a glycine- phenylalanine-rech domain. The Hsp40/DnaJ proteins play many different roles in cellular processes such as folding, translocation, degradation, and assembly of multi-protein complexes. Hdj1, the first human Hsp40/DnaJ protein identified, plays an important role in protein translation and folding as well as in regulation of Hsp70 function. Hsp40 stimulates ATPase activity of Hsp70 which in turn causes conformational changes in unfolded proteins.

FUNCTION :

Interacts with HSP70 and can stimulate its ATPase activity. Stimulates the association between HSC70 and HIP. Negatively regulates heat shock-induced HSF1 transcriptional activity during the attenuation and rPubMed:24318877, PubMed:9499401}.

DILUTION INSTRUCTIONS :

Dilute in PBS or medium which is identical to that used in the assay system.

STORAGE CONDITION :

This antibody is stable for at least one (1) year at -20C.

SPECIFICITY :

This antibody recognizes human, mouse, and rat Hsp40 (Hdj1). Other species have not been tested. It does not cross-react with Hdj2 or Ydj1.