This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Proteintech Group
product type :
antibody
product name :
beta Actin
catalog :
HRP-60008
quantity :
100UL
price :
99 USD
clonality :
monoclonal
host :
mouse
conjugate :
HRP
reactivity :
human, mouse
application :
western blot, ELISA
citations: 80
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; 1:5000; loading ...; fig 2c
Du Z, Dong J, Li M, Zhang J, Bi J, Ren Y, et al. Overexpression of Platelet-Derived Growth Factor Receptor Α D842V Mutants Prevents Liver Regeneration and Chemically Induced Hepatocarcinogenesis via Inhibition of MET and EGFR. J Cancer. 2020;11:4614-4624 pubmed publisher
  • western blot; human; loading ...; fig 1b
Xu F, Liu Z, Liu R, Lu C, Wang L, Mao W, et al. Epigenetic induction of tumor stemness via the lipopolysaccharide-TET3-HOXB2 signaling axis in esophageal squamous cell carcinoma. Cell Commun Signal. 2020;18:17 pubmed publisher
  • western blot; human; loading ...; fig s6a
Huang X, Gan G, Wang X, Xu T, Xie W. The HGF-MET axis coordinates liver cancer metabolism and autophagy for chemotherapeutic resistance. Autophagy. 2019;15:1258-1279 pubmed publisher
Yu M, Fang Z, Wang W, Zhang Y, Bu Z, Liu M, et al. Wu-5, a novel USP10 inhibitor, enhances crenolanib-induced FLT3-ITD-positive AML cell death via inhibiting FLT3 and AMPK pathways. Acta Pharmacol Sin. 2020;: pubmed publisher
Zhang J, Bi J, Ren Y, Du Z, Li T, Wang T, et al. Involvement of GPX4 in irisin's protection against ischemia reperfusion-induced acute kidney injury. J Cell Physiol. 2020;: pubmed publisher
Xiao X, Liu P, Li D, Xia Z, Wang P, Zhang X, et al. Combination therapy of BCR-ABL-positive B cell acute lymphoblastic leukemia by tyrosine kinase inhibitor dasatinib and c-JUN N-terminal kinase inhibition. J Hematol Oncol. 2020;13:80 pubmed publisher
Bobermin L, Roppa R, Goncalves C, Quincozes Santos A. Ammonia-Induced Glial-Inflammaging. Mol Neurobiol. 2020;57:3552-3567 pubmed publisher
Wang W, Chen H, Gao W, Wang S, Wu K, Lu C, et al. Girdin interaction with vimentin induces EMT and promotes the growth and metastasis of pancreatic ductal adenocarcinoma. Oncol Rep. 2020;44:637-649 pubmed publisher
Jia W, Xie L, Wang X, Zhang Q, Wei B, Li H, et al. The impact of MCM6 on hepatocellular carcinoma in a Southern Chinese Zhuang population. Biomed Pharmacother. 2020;127:110171 pubmed publisher
Beck M, Zhang Y, Bharathi S, Kosmider B, Bahmed K, Dahmer M, et al. The common K333Q polymorphism in long-chain acyl-CoA dehydrogenase (LCAD) reduces enzyme stability and function. Mol Genet Metab. 2020;: pubmed publisher
Hu Z, Zhou L, Yang S, Chen M, Yu H, Tao R, et al. FTY720 Modulates Microglia Toward Anti-inflammatory Phenotype by Suppressing Autophagy via STAT1 Pathway. Cell Mol Neurobiol. 2020;: pubmed publisher
Chen Z, Liu L, Liu Y, Wang S, Zhang S, Dong R, et al. Hydroxysafflor yellow A induces autophagy in human liver cancer cells by regulating Beclin 1 and ERK expression. Exp Ther Med. 2020;19:2989-2996 pubmed publisher
Zhang L, Wang Y, Wu G, Rao L, Wei Y, Yue H, et al. Blockade of JAK2 protects mice against hypoxia-induced pulmonary arterial hypertension by repressing pulmonary arterial smooth muscle cell proliferation. Cell Prolif. 2020;53:e12742 pubmed publisher
Huang Y, Xiao Y, Liu Y, Guo M, Guo Q, Zhou F, et al. MicroRNA-188 regulates aging-associated metabolic phenotype. Aging Cell. 2020;19:e13077 pubmed publisher
Tan Z, Huang Y, Chen F, Cao C, Wang S. Comparative Effect of Aqueous and Methanolic Bupleuri Radix Extracts on Hepatic Uptake of High-Density Lipoprotein and Identification of the Potential Target in HFD-Fed Mice. Evid Based Complement Alternat Med. 2019;2019:9074289 pubmed publisher
Qiu Q, Yu X, Yao C, Hao Y, Fan L, Li C, et al. FOXP3 pathogenic variants cause male infertility through affecting the proliferation and apoptosis of human spermatogonial stem cells. Aging (Albany NY). 2019;11:12581-12599 pubmed publisher
Si J, Ma Y, Bi J, Xiong Y, Lv C, Li S, et al. Shisa3 brakes resistance to EGFR-TKIs in lung adenocarcinoma by suppressing cancer stem cell properties. J Exp Clin Cancer Res. 2019;38:481 pubmed publisher
Su Z, Wang X, Zhou C, Chai Z. Down-regulation of miR-3068-3p enhances kcnip4-regulated A-type potassium current to protect against glutamate-induced excitotoxicity. J Neurochem. 2019;:e14932 pubmed publisher
Liu C, He X, Liu W, Yang S, Wang L, Li W, et al. Bi-allelic Mutations in TTC29 Cause Male Subfertility with Asthenoteratospermia in Humans and Mice. Am J Hum Genet. 2019;105:1168-1181 pubmed publisher
Mo Y, Wu Y, Li X, Rao H, Tian X, Wu D, et al. Osthole delays hepatocarcinogenesis in mice by suppressing AKT/FASN axis and ERK phosphorylation. Eur J Pharmacol. 2019;867:172788 pubmed publisher
Bi J, Zhang J, Ren Y, Du Z, Li T, Wang T, et al. Irisin reverses intestinal epithelial barrier dysfunction during intestinal injury via binding to the integrin αVβ5 receptor. J Cell Mol Med. 2019;: pubmed publisher
Godet I, Shin Y, Ju J, Ye I, Wang G, Gilkes D. Fate-mapping post-hypoxic tumor cells reveals a ROS-resistant phenotype that promotes metastasis. Nat Commun. 2019;10:4862 pubmed publisher
Li J, Li N, Chen Y, Hui S, Fan J, Ye B, et al. SPRY4 is responsible for pathogenesis of adolescent idiopathic scoliosis by contributing to osteogenic differentiation and melatonin response of bone marrow-derived mesenchymal stem cells. Cell Death Dis. 2019;10:805 pubmed publisher
Helsley R, Varadharajan V, Brown A, Gromovsky A, Schugar R, Ramachandiran I, et al. Obesity-linked suppression of membrane-bound O-acyltransferase 7 (MBOAT7) drives non-alcoholic fatty liver disease. elife. 2019;8: pubmed publisher
Hu X, Yang W, DU L, Cui W, Mi W, Mao Ying Q, et al. Vascular Endothelial Growth Factor A Signaling Promotes Spinal Central Sensitization and Pain-related Behaviors in Female Rats with Bone Cancer. Anesthesiology. 2019;131:1125-1147 pubmed publisher
Yang X, Zhang X, Jiao J, Zhang F, Pan Y, Wang Q, et al. Rare variants in FANCA induce premature ovarian insufficiency. Hum Genet. 2019;138:1227-1236 pubmed publisher
Li H, Yue L, Xu H, Li N, Li J, Zhang Z, et al. Curcumin suppresses osteogenesis by inducing miR-126a-3p and subsequently suppressing the WNT/LRP6 pathway. Aging (Albany NY). 2019;11:6983-6998 pubmed publisher
Li S, Jiang W, Xiao W, Li K, Zhang Y, Guo X, et al. KMT2D deficiency enhances the anti-cancer activity of L48H37 in pancreatic ductal adenocarcinoma. World J Gastrointest Oncol. 2019;11:599-621 pubmed publisher
Fan L, Ye H, Wan Y, Qin L, Zhu L, Su J, et al. Adaptor protein APPL1 coordinates HDAC3 to modulate brown adipose tissue thermogenesis in mice. Metabolism. 2019;100:153955 pubmed publisher
Zingler P, Särchen V, Glatter T, Caning L, Saggau C, Kathayat R, et al. Palmitoylation is required for TNF-R1 signaling. Cell Commun Signal. 2019;17:90 pubmed publisher
Gao Y, Yan Y, Guo J, Zhang Q, Bi D, Wang F, et al. HNF‑4α downregulation promotes tumor migration and invasion by regulating E‑cadherin in renal cell carcinoma. Oncol Rep. 2019;42:1066-1074 pubmed publisher
Wang T, Jing B, Sun B, Liao Y, Song H, Xu D, et al. Stabilization of PTGES by deubiquitinase USP9X promotes metastatic features of lung cancer via PGE2 signaling. Am J Cancer Res. 2019;9:1145-1160 pubmed
Scheiber I, Alarcon N, Zhao N. Manganese Uptake by A549 Cells is Mediated by Both ZIP8 and ZIP14. Nutrients. 2019;11: pubmed publisher
Cao X, Fang X, Malik W, He Y, Li X, Xie M, et al. TRB3 interacts with ERK and JNK and contributes to the proliferation, apoptosis, and migration of lung adenocarcinoma cells. J Cell Physiol. 2019;: pubmed publisher
Zhang Y, Bharathi S, Beck M, Goetzman E. The fatty acid oxidation enzyme long-chain acyl-CoA dehydrogenase can be a source of mitochondrial hydrogen peroxide. Redox Biol. 2019;26:101253 pubmed publisher
Zhang K, Shen Q, Fang Y, Sun Y, Ding J, Chen Y. AZD9291 inactivates the PRC2 complex to mediate tumor growth inhibition. Acta Pharmacol Sin. 2019;: pubmed publisher
Yang X, Wang X, Shao L, Jiang G, Min J, Mei X, et al. TRPV1 mediates astrocyte activation and interleukin-1β release induced by hypoxic ischemia (HI). J Neuroinflammation. 2019;16:114 pubmed publisher
Du L, Hu X, Yang W, Yasheng H, Liu S, Zhang W, et al. Spinal IL-33/ST2 signaling mediates chronic itch in mice through the astrocytic JAK2-STAT3 cascade. Glia. 2019;: pubmed publisher
Xu L, Jing M, Yang L, Jin L, Gong P, Lu J, et al. The Alisma and Rhizoma decoction abates nonalcoholic steatohepatitis-associated liver injuries in mice by modulating oxidative stress and autophagy. BMC Complement Altern Med. 2019;19:92 pubmed publisher
Li L, He S, Yu L, Elshazly E, Wang H, Chen K, et al. Codelivery of DOX and siRNA by folate-biotin-quaternized starch nanoparticles for promoting synergistic suppression of human lung cancer cells. Drug Deliv. 2019;26:499-508 pubmed publisher
Scheiber I, Wu Y, Morgan S, Zhao N. The intestinal metal transporter ZIP14 maintains systemic manganese homeostasis. J Biol Chem. 2019;294:9147-9160 pubmed publisher
Feng H, Fang F, Yuan L, Xiao M, Yang X, Huang Y. Downregulated expression of CFHL1 is associated with unfavorable prognosis in postoperative patients with hepatocellular carcinoma. Exp Ther Med. 2019;17:4073-4079 pubmed publisher
Wang Y, Ju L, Xiao F, Liu H, Luo X, Chen L, et al. Downregulation of nucleolar and spindle-associated protein 1 expression suppresses liver cancer cell function. Exp Ther Med. 2019;17:2969-2978 pubmed publisher
Kuang Y, Guo W, Ling J, Xu D, Liao Y, Zhao H, et al. Iron-dependent CDK1 activity promotes lung carcinogenesis via activation of the GP130/STAT3 signaling pathway. Cell Death Dis. 2019;10:297 pubmed publisher
Zheng Z, Sun R, Zhao H, Fu D, Zhong H, Weng X, et al. MiR155 sensitized B-lymphoma cells to anti-PD-L1 antibody via PD-1/PD-L1-mediated lymphoma cell interaction with CD8+T cells. Mol Cancer. 2019;18:54 pubmed publisher
Wu Y, Tan X, Liu P, Yang Y, Huang Y, Liu X, et al. ITGA6 and RPSA synergistically promote pancreatic cancer invasion and metastasis via PI3K and MAPK signaling pathways. Exp Cell Res. 2019;379:30-47 pubmed publisher
Li Y, Zhao C, Liu J, Lu Z, Lu M, Gu J, et al. CD1d highly expressed on DCs reduces lung tumor burden by enhancing antitumor immunity. Oncol Rep. 2019;41:2679-2688 pubmed publisher
Hu M, Guo W, Liao Y, Xu D, Sun B, Song H, et al. Dysregulated ENPP1 increases the malignancy of human lung cancer by inducing epithelial-mesenchymal transition phenotypes and stem cell features. Am J Cancer Res. 2019;9:134-144 pubmed
Zhang Z, Sun C, Zhang L, Chi X, Ji J, Gao X, et al. Triptolide interferes with XRCC1/PARP1-mediated DNA repair and confers sensitization of triple-negative breast cancer cells to cisplatin. Biomed Pharmacother. 2019;109:1541-1546 pubmed publisher
Li J, Li B, Cheng Y, Meng Q, Wei L, Li W, et al. The synergistic effect of NOD2 and TLR4 on the activation of autophagy in human submandibular gland inflammation. J Oral Pathol Med. 2019;48:87-95 pubmed publisher
Su Z, Han Y, Sun Q, Wang X, Xu T, Xie W, et al. Anti-MET VHH Pool Overcomes MET-Targeted Cancer Therapeutic Resistance. Mol Cancer Ther. 2019;18:100-111 pubmed publisher
Wang J, Yu R, Han Q, Huang H, Wang Y, Li H, et al. G-1 exhibit antidepressant effect, increase of hippocampal ERs expression and improve hippocampal redox status in aged female rats. Behav Brain Res. 2019;359:845-852 pubmed publisher
Tang Y, Wang C, Wang Y, Zhang J, Wang F, Li L, et al. Isoliquiritigenin attenuates LPS-induced AKI by suppression of inflammation involving NF-κB pathway. Am J Transl Res. 2018;10:4141-4151 pubmed
Chen M, Zheng F, Yuan G, Duan X, Rong L, Liu J, et al. Development of an Infectious Cell Culture System for Hepatitis C Virus Genotype 6a Clinical Isolate Using a Novel Strategy and Its Sensitivity to Direct-Acting Antivirals. Front Microbiol. 2018;9:2950 pubmed publisher
Huang Z, Zhao J, Deng W, Chen Y, Shang J, Song K, et al. Identification of a cellularly active SIRT6 allosteric activator. Nat Chem Biol. 2018;14:1118-1126 pubmed publisher
Bianchi Smiraglia A, Bagati A, Fink E, Affronti H, Lipchick B, Moparthy S, et al. Inhibition of the aryl hydrocarbon receptor/polyamine biosynthesis axis suppresses multiple myeloma. J Clin Invest. 2018;128:4682-4696 pubmed publisher
Duan X, Anwar M, Xu Z, Ma L, Yuan G, Chen Y, et al. Adaptive mutation F772S-enhanced p7-NS4A cooperation facilitates the assembly and release of hepatitis C virus and is associated with lipid droplet enlargement. Emerg Microbes Infect. 2018;7:143 pubmed publisher
Chang C, Keppeke G, Sung L, Liu J. Interfilament interaction between IMPDH and CTPS cytoophidia. FEBS J. 2018;285:3753-3768 pubmed publisher
Ahmed Z, Li X, Li F, Cheaito H, Patel K, Mosallam E, et al. Computational and biochemical studies of isothiocyanates as inhibitors of proteasomal cysteine deubiquitinases in human cancer cells. J Cell Biochem. 2018;119:9006-9016 pubmed publisher
Keppeke G, Chang C, Peng M, Chen L, Lin W, Pai L, et al. IMP/GTP balance modulates cytoophidium assembly and IMPDH activity. Cell Div. 2018;13:5 pubmed publisher
Luo W, Min J, Huang W, Wang X, Peng Y, Han S, et al. Vitexin reduces epilepsy after hypoxic ischemia in the neonatal brain via inhibition of NKCC1. J Neuroinflammation. 2018;15:186 pubmed publisher
Sun J, Guo Y, Zhang Q, Bu S, Li B, Wang Q, et al. Chronic restraint stress disturbs meiotic resumption through APC/C-mediated cyclin B1 excessive degradation in mouse oocytes. Cell Cycle. 2018;17:1591-1601 pubmed publisher
Li J, Zeng C, Zheng B, Liu C, Tang M, Jiang Y, et al. HMGB1-induced autophagy facilitates hepatic stellate cells activation: a new pathway in liver fibrosis. Clin Sci (Lond). 2018;132:1645-1667 pubmed publisher
Linetsky M, Bondelid K, Losovskiy S, Gabyak V, Rullo M, Stiadle T, et al. 4-Hydroxy-7-oxo-5-heptenoic Acid Lactone Is a Potent Inducer of the Complement Pathway in Human Retinal Pigmented Epithelial Cells. Chem Res Toxicol. 2018;31:666-679 pubmed publisher
Plafker K, Zyla K, Berry W, Plafker S. Loss of the ubiquitin conjugating enzyme UBE2E3 induces cellular senescence. Redox Biol. 2018;17:411-422 pubmed publisher
Cen B, Liao W, Wang Z, Gao L, Wei Y, Huang W, et al. Gelofusine Attenuates Tubulointerstitial Injury Induced by cRGD-Conjugated siRNA by Regulating the TLR3 Signaling Pathway. Mol Ther Nucleic Acids. 2018;11:300-311 pubmed publisher
Sulkowski P, Scanlon S, Oeck S, Glazer P. PTEN Regulates Nonhomologous End Joining By Epigenetic Induction of NHEJ1/XLF. Mol Cancer Res. 2018;16:1241-1254 pubmed publisher
Fan F, Zhao J, Liu Y, Zhao H, Weng L, Li Q, et al. Identifying the SUMO1 modification of FAM122A leading to the degradation of PP2A-C? by ubiquitin-proteasome system. Biochem Biophys Res Commun. 2018;500:676-681 pubmed publisher
Luo Y, Chen X, Luo L, Zhang Q, Gao C, Zhuang X, et al. [6]-Gingerol enhances the radiosensitivity of gastric cancer via G2/M phase arrest and apoptosis induction. Oncol Rep. 2018;39:2252-2260 pubmed publisher
Xu K, Pei H, Zhang Z, Wang H, Li L, Xia Q. Ubiquitin-specific protease 15 promotes tumor cell invasion and proliferation in glioblastoma. Oncol Lett. 2018;15:3846-3851 pubmed publisher
Xu K, Qiu C, Pei H, Mehmood M, Wang H, Li L, et al. Homeobox B3 promotes tumor cell proliferation and invasion in glioblastoma. Oncol Lett. 2018;15:3712-3718 pubmed publisher
Cao J, Lin Y, Han Y, Ding S, Fan Y, Pan Y, et al. Expression of nerve growth factor carried by pseudotyped lentivirus improves neuron survival and cognitive functional recovery of post-ischemia in rats. CNS Neurosci Ther. 2018;24:508-518 pubmed publisher
Wang H, Yuan Q, Niu M, Zhang W, Wen L, Fu H, et al. Transcriptional regulation of P63 on the apoptosis of male germ cells and three stages of spermatogenesis in mice. Cell Death Dis. 2018;9:76 pubmed publisher
Wang X, Wang L, Garcia J, Dudek S, Shekhawat G, Dravid V. The Significant Role of c-Abl Kinase in Barrier Altering Agonists-mediated Cytoskeletal Biomechanics. Sci Rep. 2018;8:1002 pubmed publisher
Ding H, Wei J, Zhao Y, Liu Y, Liu L, Cheng L. Progranulin derived engineered protein Atsttrin suppresses TNF-?-mediated inflammation in intervertebral disc degenerative disease. Oncotarget. 2017;8:109692-109702 pubmed publisher
Zhang Y, Igwe O. Lipopolysaccharide (LPS)-mediated priming of toll-like receptor 4 enhances oxidant-induced prostaglandin E2 biosynthesis in primary murine macrophages. Int Immunopharmacol. 2018;54:226-237 pubmed publisher
Ni X, Cao X, Wu Y, Wu J. FSTL1 suppresses tumor cell proliferation, invasion and survival in non-small cell lung cancer. Oncol Rep. 2018;39:13-20 pubmed publisher
Li L, Liu L, Qu B, Li X, Gao X, Zhang M. Twinfilin 1 enhances milk bio-synthesis and proliferation of bovine mammary epithelial cells via the mTOR signaling pathway. Biochem Biophys Res Commun. 2017;492:289-294 pubmed publisher
Fu R, He W, Wang X, Li L, Zhao H, Liu X, et al. DNMT1-maintained hypermethylation of Krüppel-like factor 5 involves in the progression of clear cell renal cell carcinoma. Cell Death Dis. 2017;8:e2952 pubmed publisher
Huang Y, Wang J, Ghosh S, Liu J. Critical roles of CTP synthase N-terminal in cytoophidium assembly. Exp Cell Res. 2017;354:122-133 pubmed publisher
product information
CatalogNo :
HRP-60008
AntigenName :
beta Actin
Package :
100UL
Price :
99 USD
FullName :
actin, beta
Immunogen :
Recombinant Protein
Species :
chinese hamster, human, mouse, plant, rat, zebrafish
Host :
Mouse
IsConjugated :
HRP
AntigenSpecies :
human
Application :
WB, ELISA
Clonlity :
Monoclonal
IsoType :
IgM
Synonyms :
ACTB, Actin, actin, beta, Actin, cytoplasmic 1, B actin, Beta actin, F actin, HRP β actin, HRP-ACTB, HRP-Beta actin, HRP-F actin, PS1TP5BP1, β actin
PrimaryOrSecondary :
Primary
AntibodyBuffer :
PBS with 0.02% Thimerosal, 50% Glycerol, pH 7.3.
GenBankNo :
BC002409
Category :
Binding Proteins;Cell Cycle;Cytoskeleton/Scaffold Proteins;Metabolism;Transport/Trafficking;
PurifyMethod :
Caprylic acid/ammonium sulfate precipitation
NewAb :
False
IsSellable :
True
AppTiter :
WB 1:8000 ;
company information
Proteintech Group
2201 W. Campbell Park Dr. STE12
Chicago, IL 60612
Proteintech@ptglab.com
https://www.ptglab.com
1-312-455-8498
headquarters: USA
At Proteintech, we produce every single antibody we sell; we do not rely on or supply to any other antibody providers: our products are unique and we are 100% accountable for each one. We realize this accountability by validating in-house, providing extensive technical support and guaranteeing your success: in addition to helping you troubleshoot your experiment, we will offer you a full cash refund if you are in any way dissatisfied. We can guarantee satisfaction because we have confidence in our products, confidence cultivated by the science behind our antibodies: we make them using as much of the native protein as possible, and purifying them using affinity purification with the original antigen. We carry out antibody production over a 102-day period, which allows for better antigen fitting to MHC molecules and affinity maturation in the host. This approach results in higher affinity antibodies with greater sensitivity, which you can use in any application and in multiple species.
You can only buy Proteintech antibodies directly from Proteintech or via one of its approved distributors — when you receive your antibody and see the Proteintech logo on the vial, know that you hold something that is truly unique.