This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Proteintech Group
product type :
antibody
product name :
TRAF6
catalog :
66498-1-Ig
quantity :
150UL
price :
299 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
1D1E1
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry
citations: 17
Reference
He Y, Ruganzu J, Jin H, Peng X, Ji S, Ma Y, et al. LRP1 knockdown aggravates Aβ1-42-stimulated microglial and astrocytic neuroinflammatory responses by modulating TLR4/NF-κB/MAPKs signaling pathways. Exp Cell Res. 2020;394:112166 pubmed publisher
He Y, Ruganzu J, Zheng Q, Wu X, Jin H, Peng X, et al. Silencing of LRP1 Exacerbates Inflammatory Response Via TLR4/NF-κB/MAPKs Signaling Pathways in APP/PS1 Transgenic Mice. Mol Neurobiol. 2020;57:3727-3743 pubmed publisher
Guan L, Li C, Zhang Y, Gong J, Wang G, Tian P, et al. Puerarin ameliorates retinal ganglion cell damage induced by retinal ischemia/reperfusion through inhibiting the activation of TLR4/NLRP3 inflammasome. Life Sci. 2020;256:117935 pubmed publisher
Liu G, Zhang Q, Gao X, Wang H, Tao T, Gao Y, et al. MiR-146a Ameliorates Hemoglobin-Induced Microglial Inflammatory Response via TLR4/IRAK1/TRAF6 Associated Pathways. Front Neurosci. 2020;14:311 pubmed publisher
Meng Q, Liang C, Hua J, Zhang B, Liu J, Zhang Y, et al. A miR-146a-5p/TRAF6/NF-kB p65 axis regulates pancreatic cancer chemoresistance: functional validation and clinical significance. Theranostics. 2020;10:3967-3979 pubmed publisher
Zavaczki E, Gáll T, Zarjou A, Hendrik Z, Potor L, Tóth C, et al. Ferryl Hemoglobin Inhibits Osteoclastic Differentiation of Macrophages in Hemorrhaged Atherosclerotic Plaques. Oxid Med Cell Longev. 2020;2020:3721383 pubmed publisher
Szulc Kielbik I, Kielbik M, Przygodzka P, Brzostek A, Dziadek J, Klink M. Mycobacterium tuberculosis Requires Cholesterol Oxidase to Disrupt TLR2 Signalling in Human Macrophages. Mediators Inflamm. 2019;2019:2373791 pubmed publisher
Du Y, Qian B, Gao L, Tan P, Chen H, Wang A, et al. Aloin Preconditioning Attenuates Hepatic Ischemia/Reperfusion Injury via Inhibiting TLR4/MyD88/NF-κB Signal Pathway In Vivo and In Vitro. Oxid Med Cell Longev. 2019;2019:3765898 pubmed publisher
Fei Y, Chaulagain A, Wang T, Chen Y, Liu J, Yi M, et al. MiR-146a down-regulates inflammatory response by targeting TLR3 and TRAF6 in Coxsackievirus B infection. RNA. 2019;: pubmed publisher
Liu Y, Jiang Q, Liu X, Lin X, Tang Z, Liu C, et al. Cinobufotalin powerfully reversed EBV-miR-BART22-induced cisplatin resistance via stimulating MAP2K4 to antagonize non-muscle myosin heavy chain IIA/glycogen synthase 3β/β-catenin signaling pathway. EBioMedicine. 2019;48:386-404 pubmed publisher
Sun S, Li F, Liu Y, Qu H, Wong S, Zeng L, et al. A novel inhibitor of nuclear factor kappa-B kinase subunit gamma mutation identified in an incontinentia pigmenti patient with syndromic tooth agenesis. Arch Oral Biol. 2019;101:100-107 pubmed publisher
Song P, Yang S, Hua H, Zhang H, Kong Q, Wang J, et al. The regulatory protein GADD34 inhibits TRAIL-induced apoptosis via TRAF6/ERK-dependent stabilization of myeloid cell leukemia 1 in liver cancer cells. J Biol Chem. 2019;294:5945-5955 pubmed publisher
Yu Q, Liu T, Li S, Feng J, Wu L, Wang W, et al. The Protective Effects of Levo-Tetrahydropalmatine on ConA-Induced Liver Injury Are via TRAF6/JNK Signaling. Mediators Inflamm. 2018;2018:4032484 pubmed publisher
Xie Y, Chu A, Feng Y, Chen L, Shao Y, Luo Q, et al. MicroRNA-146a: A Comprehensive Indicator of Inflammation and Oxidative Stress Status Induced in the Brain of Chronic T2DM Rats. Front Pharmacol. 2018;9:478 pubmed publisher
Wang Y, Xu H, Jiao H, Wang S, Xiao Z, Zhao Y, et al. STX2 promotes colorectal cancer metastasis through a positive feedback loop that activates the NF-?B pathway. Cell Death Dis. 2018;9:664 pubmed publisher
Fu Y, Zhang L, Zhang F, Tang T, Zhou Q, Feng C, et al. Exosome-mediated miR-146a transfer suppresses type I interferon response and facilitates EV71 infection. PLoS Pathog. 2017;13:e1006611 pubmed publisher
Wang B, Zhao H, Zhao L, Zhang Y, Wan Q, Shen Y, et al. Up-regulation of OLR1 expression by TBC1D3 through activation of TNFα/NF-κB pathway promotes the migration of human breast cancer cells. Cancer Lett. 2017;408:60-70 pubmed publisher
product information
CatalogNo :
66498-1-Ig
AntigenName :
TRAF6
Package :
150UL
Price :
299 USD
Exsists20ul :
20ul trial size available
FullName :
TNF receptor-associated factor 6
Immunogen :
Recombinant protein
Species :
human, mouse, rat
Host :
Mouse
IsConjugated :
Unconjugated
AntigenSpecies :
human
CloneNo :
1D1E1
Application :
WB, IHC, IF, ELISA
Clonlity :
Monoclonal
IsoType :
IgG1
Synonyms :
RING finger protein 85, RNF85, TRAF6
PrimaryOrSecondary :
Primary
AntibodyBuffer :
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
GenBankNo :
BC031052
PurifyMethod :
Protein A purification
NewAb :
False
IsSellable :
True
Feature :
siRNA
AppTiter :
IF 1:100 ; IHC 1:600 ; WB 1:20000 ;
company information
Proteintech Group
2201 W. Campbell Park Dr. STE12
Chicago, IL 60612
Proteintech@ptglab.com
https://www.ptglab.com
1-312-455-8498
headquarters: USA
At Proteintech, we produce every single antibody we sell; we do not rely on or supply to any other antibody providers: our products are unique and we are 100% accountable for each one. We realize this accountability by validating in-house, providing extensive technical support and guaranteeing your success: in addition to helping you troubleshoot your experiment, we will offer you a full cash refund if you are in any way dissatisfied. We can guarantee satisfaction because we have confidence in our products, confidence cultivated by the science behind our antibodies: we make them using as much of the native protein as possible, and purifying them using affinity purification with the original antigen. We carry out antibody production over a 102-day period, which allows for better antigen fitting to MHC molecules and affinity maturation in the host. This approach results in higher affinity antibodies with greater sensitivity, which you can use in any application and in multiple species.
You can only buy Proteintech antibodies directly from Proteintech or via one of its approved distributors — when you receive your antibody and see the Proteintech logo on the vial, know that you hold something that is truly unique.