This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Proteintech Group
product type :
antibody
product name :
Caspase 3/p17/p19
catalog :
66470-2-Ig
quantity :
150UL
price :
299 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
2G4B2
reactivity :
human, mouse
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry
citations: 27
Published Application/Species/Sample/DilutionReference
  • western blot; human; 1:1000; loading ...; fig 2b
Liu X, Huang J, Xie Y, Zhou Y, Wang R, Lou J. Napabucasin Attenuates Resistance of Breast Cancer Cells to Tamoxifen by Reducing Stem Cell-Like Properties. Med Sci Monit. 2019;25:8905-8912 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 3b
Yue G, Chen C, Bai L, Wang G, Huang Y, Wang Y, et al. Knockdown of long noncoding RNA DLEU1 suppresses the progression of renal cell carcinoma by downregulating the Akt pathway. Mol Med Rep. 2019;20:4551-4557 pubmed publisher
  • western blot; mouse; 1:500; loading ...; fig 7a
Liu P, Yao R, Shi H, Liu Y, Lian S, Yang Y, et al. Effects of Cold-inducible RNA-binding Protein (CIRP) on Liver Glycolysis during Acute Cold Exposure in C57BL/6 Mice. Int J Mol Sci. 2019;20: pubmed publisher
  • western blot; mouse; loading ...; fig s1b
Chen C, Zou L, Lin Q, Yan X, Bi H, Xie X, et al. Resveratrol as a new inhibitor of immunoproteasome prevents PTEN degradation and attenuates cardiac hypertrophy after pressure overload. Redox Biol. 2019;20:390-401 pubmed publisher
Yu Q, Xin H, Qiu R, Deng Z, Deng F, Yan Z. Niclosamide: drug repurposing for human chondrosarcoma treatment via the caspase-dependent mitochondrial apoptotic pathway. Am J Transl Res. 2020;12:3688-3701 pubmed
Feng Q, Bian X, Liu X, Wang Y, Zhou H, Ma X, et al. Intracellular expression of arginine deiminase activates the mitochondrial apoptosis pathway by inhibiting cytosolic ferritin and inducing chromatin autophagy. BMC Cancer. 2020;20:665 pubmed publisher
Zhao X, Fu J, Tang W, Yu L, Xu W. Inhibition of Serine Metabolism Promotes Resistance to Cisplatin in Gastric Cancer. Onco Targets Ther. 2020;13:4833-4842 pubmed publisher
Wang J, Zhou X, Wang H, Xiao Q, Ding K, Dong X, et al. Autophagy-inhibiting polymer as an effective nonviral cancer gene therapy vector with inherent apoptosis-sensitizing ability. Biomaterials. 2020;255:120156 pubmed publisher
Wang M, Zhang M, Feng Y, Xing Y, Tan Z, Li W, et al. Electroacupuncture Inhibits Neuronal Autophagy and Apoptosis via the PI3K/AKT Pathway Following Ischemic Stroke. Front Cell Neurosci. 2020;14:134 pubmed publisher
Gurkaslar H, Culfa E, Arslanhan M, Lince Faria M, Firat Karalar E. CCDC57 Cooperates with Microtubules and Microcephaly Protein CEP63 and Regulates Centriole Duplication and Mitotic Progression. Cell Rep. 2020;31:107630 pubmed publisher
Sun Z, Zeng L, Zhang M, Zhang Y, Yang N. PIM1 inhibitor synergizes the anti-tumor effect of osimertinib via STAT3 dephosphorylation in EGFR-mutant non-small cell lung cancer. Ann Transl Med. 2020;8:366 pubmed publisher
Bai X, Wang Y, Hu B, Cao Q, Xing M, Song S, et al. Fucoidan Induces Apoptosis of HT-29 Cells via the Activation of DR4 and Mitochondrial Pathway. Mar Drugs. 2020;18: pubmed publisher
Jia L, Wang J, Cao H, Zhang X, Rong W, Xu Z. Activation of PGC-1α and Mitochondrial Biogenesis Protects Against Prenatal Hypoxic-ischemic Brain Injury. Neuroscience. 2020;432:63-72 pubmed publisher
Leung M, Tsoi H, Gong C, Man E, Zona S, YAO S, et al. A Splice Variant of NCOR2, BQ323636.1, Confers Chemoresistance in Breast Cancer by Altering the Activity of NRF2. Cancers (Basel). 2020;12: pubmed publisher
Hao Y, Guo F, Huang Z, Feng Y, Xia Z, Liu J, et al. 2-Methylquinazoline derivative 23BB as a highly selective histone deacetylase 6 inhibitor alleviated cisplatin-induced acute kidney injury. Biosci Rep. 2020;40: pubmed publisher
Li K, Feng Z, Ou Y, Zhou M, Peng J, Gong H, et al. [JNK/c-Jun signaling pathway mediates arginine vasopressin neuron regeneration by promoting cytoskeleton reconstruction in rats with electrical lesions of the pituitary stalk]. Nan Fang Yi Ke Da Xue Xue Bao. 2019;39:1099-1106 pubmed publisher
Chen S, Wang J, Wang L, Peng H, Xiao L, Li C, et al. Silencing TTK expression inhibits the proliferation and progression of prostate cancer. Exp Cell Res. 2019;385:111669 pubmed publisher
Jin X, Liang Y, Liu D, Luo Q, Cai L, Wu J, et al. An essential role for GLUT5-mediated fructose utilization in exacerbating the malignancy of clear cell renal cell carcinoma. Cell Biol Toxicol. 2019;: pubmed publisher
Lan H, Su Y, Liu Y, Deng C, Wang J, Chen T, et al. Melatonin protects circulatory death heart from ischemia/reperfusion injury via the JAK2/STAT3 signalling pathway. Life Sci. 2019;228:35-46 pubmed publisher
Chen C, Gao R, Li M, Wang Q, Chen H, Zhang S, et al. Extracellular RNAs-TLR3 signaling contributes to cognitive decline in a mouse model of postoperative cognitive dysfunction. Brain Behav Immun. 2019;: pubmed publisher
Cao P, Feng Y, Deng M, Li J, Cai H, Meng Q, et al. MiR-15b is a key regulator of proliferation and apoptosis of chondrocytes from patients with condylar hyperplasia by targeting IGF1, IGF1R and BCL2. Osteoarthritis Cartilage. 2019;27:336-346 pubmed publisher
Ou B, Tao W, Yang S, Feng J, Wang J, Yang T, et al. The Antiapoptosis Effect of Geum japonicum Thunb. var. chinense Extracts on Cerebral Ischemia Reperfusion Injury via PI3K/Akt Pathway. Evid Based Complement Alternat Med. 2018;2018:7290170 pubmed publisher
Juan C, Wang Q, Mao Y, Cao Q, Li S, Qiao C, et al. Knockdown of LncRNA MALAT1 contributes to cell apoptosis via regulating NF-κB/CD80 axis in neonatal respiratory distress syndrome. Int J Biochem Cell Biol. 2018;104:138-148 pubmed publisher
Liu M, Liu S, Tan W, Tang F, Long J, Li Z, et al. Gaseous signalling molecule SO2 via Hippo?MST pathway to improve myocardial fibrosis of diabetic rats. Mol Med Rep. 2017;16:8953-8963 pubmed publisher
Yuan K, Zhao G, Che C, Li C, Lin J, Zhu G, et al. Dectin-1 is essential for IL-1? production through JNK activation and apoptosis in Aspergillus fumigatus keratitis. Int Immunopharmacol. 2017;52:168-175 pubmed publisher
Song Y, Kong L, Sun B, Gao L, Chu P, Ahsan A, et al. Induction of autophagy by an oleanolic acid derivative, SZC017, promotes ROS-dependent apoptosis through Akt and JAK2/STAT3 signaling pathway in human lung cancer cells. Cell Biol Int. 2017;41:1367-1378 pubmed publisher
Zou J, Zhang Y, Sun J, Wang X, Tu H, Geng S, et al. Deoxyelephantopin Induces Reactive Oxygen Species-Mediated Apoptosis and Autophagy in Human Osteosarcoma Cells. Cell Physiol Biochem. 2017;42:1812-1821 pubmed publisher
product information
CatalogNo :
66470-2-Ig
AntigenName :
Caspase 3/p17/p19
Package :
150UL
Price :
299 USD
Exsists20ul :
20ul trial size available
FullName :
caspase 3, apoptosis-related cysteine peptidase
Immunogen :
Recombinant protein
Species :
human, mouse, rat
Host :
Mouse
IsConjugated :
Unconjugated
AntigenSpecies :
human
CloneNo :
2G4B2
Application :
WB, IHC, IF, ELISA
Clonlity :
Monoclonal
IsoType :
IgG1
Synonyms :
Apopain, CASP 3, CASP3, Caspase 3, Caspase3, Caspase-3, CPP 32, CPP32, CPP32B, Cysteine protease CPP32, Protein Yama, SCA 1, SREBP cleavage activity 1
PrimaryOrSecondary :
Primary
AntibodyBuffer :
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
GenBankNo :
BC016926
PurifyMethod :
Protein A purification
NewAb :
False
IsSellable :
True
Feature :
siRNA
AppTiter :
IF 1:100 ; IHC 1:300 ; WB 1:3000 ;
company information
Proteintech Group
2201 W. Campbell Park Dr. STE12
Chicago, IL 60612
Proteintech@ptglab.com
https://www.ptglab.com
1-312-455-8498
headquarters: USA
At Proteintech, we produce every single antibody we sell; we do not rely on or supply to any other antibody providers: our products are unique and we are 100% accountable for each one. We realize this accountability by validating in-house, providing extensive technical support and guaranteeing your success: in addition to helping you troubleshoot your experiment, we will offer you a full cash refund if you are in any way dissatisfied. We can guarantee satisfaction because we have confidence in our products, confidence cultivated by the science behind our antibodies: we make them using as much of the native protein as possible, and purifying them using affinity purification with the original antigen. We carry out antibody production over a 102-day period, which allows for better antigen fitting to MHC molecules and affinity maturation in the host. This approach results in higher affinity antibodies with greater sensitivity, which you can use in any application and in multiple species.
You can only buy Proteintech antibodies directly from Proteintech or via one of its approved distributors — when you receive your antibody and see the Proteintech logo on the vial, know that you hold something that is truly unique.