This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Proteintech Group
product type :
antibody
product name :
PGC1a
catalog :
66369-1-Ig
quantity :
150UL
price :
299 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
1C1B2
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry
citations: 39
Reference
Zhang L, Wang Y, Ju J, Shabanova A, Li Y, Fang R, et al. Mzb1 protects against myocardial infarction injury in mice via modulating mitochondrial function and alleviating inflammation. Acta Pharmacol Sin. 2020;: pubmed publisher
Zhong X, Ma Z, Su Y, Li Z, Liao Y, Pan X, et al. Flavin adenine dinucleotide ameliorates hypertensive vascular remodeling via activating short chain acyl-CoA dehydrogenase. Life Sci. 2020;258:118156 pubmed publisher
Xiang Y, Fang B, Liu Y, Yan S, Cao D, Mei H, et al. SR18292 exerts potent antitumor effects in multiple myeloma via inhibition of oxidative phosphorylation. Life Sci. 2020;256:117971 pubmed publisher
Son J, Zhao L, Chen Y, Chen K, Chae S, de Avila J, et al. Maternal exercise via exerkine apelin enhances brown adipogenesis and prevents metabolic dysfunction in offspring mice. Sci Adv. 2020;6:eaaz0359 pubmed publisher
Zhang C, Jia Y, Liu B, Wang G, Zhang Y. TLR4 knockout upregulates the expression of Mfn2 and PGC-1α in a high-fat diet and ischemia-reperfusion mice model of liver injury. Life Sci. 2020;254:117762 pubmed publisher
Li L, Jiang Z, Yao Y, Yang Z, Ma H. (-)-Hydroxycitric acid regulates energy metabolism by activation of AMPK - PGC1α - NRF1 signal pathway in primary chicken hepatocytes. Life Sci. 2020;254:117785 pubmed publisher
Chen Y, Hu Y, Yang Q, Son J, Liu X, de Avila J, et al. Excessive Glucocorticoids During Pregnancy Impair Fetal Brown Fat Development and Predispose Offspring to Metabolic Dysfunctions. Diabetes. 2020;69:1662-1674 pubmed publisher
Wei M, Huang F, Zhao L, Zhang Y, Yang W, Wang S, et al. A dysregulated bile acid-gut microbiota axis contributes to obesity susceptibility. EBioMedicine. 2020;55:102766 pubmed publisher
Li J, Li Y, Chen L, Yu B, Xue Y, Guo R, et al. p53/PGC‑1α‑mediated mitochondrial dysfunction promotes PC3 prostate cancer cell apoptosis. Mol Med Rep. 2020;22:155-164 pubmed publisher
Liu Y, Xu F, Jiang P. Effect of sitagliptin on expression of skeletal muscle peroxisome proliferator-activated receptor γ coactivator-1α and irisin in a rat model of type 2 diabetes mellitus. J Int Med Res. 2020;48:300060519885569 pubmed publisher
Zhang Q, Ma X, Dong M, Tan J, Zhang J, Zhuang L, et al. MiR-30b-5p regulates the lipid metabolism by targeting PPARGC1A in Huh-7 cell line. Lipids Health Dis. 2020;19:76 pubmed publisher
Qi J, Chen X, Wu Q, Wang J, Zhang H, Mao A, et al. Fasting Induces Hepatocellular Carcinoma Cell Apoptosis by Inhibiting SET8 Expression. Oxid Med Cell Longev. 2020;2020:3985089 pubmed publisher
Wang Y, Gao M, Zhu F, Li X, Yang Y, Yan Q, et al. METTL3 is essential for postnatal development of brown adipose tissue and energy expenditure in mice. Nat Commun. 2020;11:1648 pubmed publisher
Luo J, Tang C, Chen X, Ren Z, Qu H, Chen R, et al. Impacts of Aerobic Exercise on Depression-Like Behaviors in Chronic Unpredictable Mild Stress Mice and Related Factors in the AMPK/PGC-1α Pathway. Int J Environ Res Public Health. 2020;17: pubmed publisher
Lai H, Nie T, Zhang Y, Chen Y, Tao J, Lin T, et al. Selenium Deficiency-Induced Damage and Altered Expression of Mitochondrial Biogenesis Markers in the Kidneys of Mice. Biol Trace Elem Res. 2020;: pubmed publisher
Zhu Z, Li H, Chen W, Cui Y, Huang A, Qi X. Perindopril Improves Cardiac Function by Enhancing the Expression of SIRT3 and PGC-1α in a Rat Model of Isoproterenol-Induced Cardiomyopathy. Front Pharmacol. 2020;11:94 pubmed publisher
Li Y, Lu J, Cao X, Zhao H, Gao L, Xia P, et al. A Newly Synthesized Rhamnoside Derivative Alleviates Alzheimer's Amyloid-β-Induced Oxidative Stress, Mitochondrial Dysfunction, and Cell Senescence through Upregulating SIRT3. Oxid Med Cell Longev. 2020;2020:7698560 pubmed publisher
Zhu R, Wei J, Liu H, Liu C, Wang L, Chen B, et al. Lycopene attenuates body weight gain through induction of browning via regulation of peroxisome proliferator-activated receptor γ in high-fat diet-induced obese mice. J Nutr Biochem. 2020;78:108335 pubmed publisher
Niu Y, Zhou W, Nie Z, Zhou D, Xu Y, Ock S, et al. Ubiquinol-10 delays postovulatory oocyte aging by improving mitochondrial renewal in pigs. Aging (Albany NY). 2020;12:1256-1271 pubmed publisher
Pereira C, Peralta S, Arguello T, Bacman S, Diaz F, Moraes C. Myopathy reversion in mice after restauration of mitochondrial complex I. EMBO Mol Med. 2020;12:e10674 pubmed publisher
Fan G, Dang X, Li Y, Chen J, Zhao R, Yang X. Zinc-α2-glycoprotein promotes browning of white adipose tissue in cold-exposed male mice. Mol Cell Endocrinol. 2020;501:110669 pubmed publisher
Li L, Zhao H, Chen B, Fan Z, Li N, Yue J, et al. FXR activation alleviates tacrolimus-induced post-transplant diabetes mellitus by regulating renal gluconeogenesis and glucose uptake. J Transl Med. 2019;17:418 pubmed publisher
Lv X, Wang X, Wang Y, Zhou D, Li W, Wilson J, et al. Folic acid delays age-related cognitive decline in senescence-accelerated mouse prone 8: alleviating telomere attrition as a potential mechanism. Aging (Albany NY). 2019;11:10356-10373 pubmed publisher
Chen T, Peng S, Wang Y, Hu Y, Shen Y, Xu Y, et al. Improvement of Mitochondrial Activity and Fibrosis by Resveratrol Treatment in Mice with Schistosoma japonicum Infection. Biomolecules. 2019;9: pubmed publisher
Essandoh K, Wang X, Huang W, Deng S, Gardner G, Mu X, et al. Tumor susceptibility gene 101 ameliorates endotoxin-induced cardiac dysfunction by enhancing Parkin-mediated mitophagy. J Biol Chem. 2019;294:18057-18068 pubmed publisher
Wang X, Li S, Liu L, Jian Z, Cui T, Yang Y, et al. Role of the aryl hydrocarbon receptor signaling pathway in promoting mitochondrial biogenesis against oxidative damage in human melanocytes. J Dermatol Sci. 2019;96:33-41 pubmed publisher
Yang Q, Wang C, Jin Y, Ma X, Xie T, Wang J, et al. Disocin prevents postmenopausal atherosclerosis in ovariectomized LDLR-/- mice through a PGC-1α/ERα pathway leading to promotion of autophagy and inhibition of oxidative stress, inflammation and apoptosis. Pharmacol Res. 2019;148:104414 pubmed publisher
Peng J, Xiong J, Cui C, Huang N, Zhang H, Wu X, et al. Maternal Eicosapentaenoic Acid Feeding Decreases Placental Lipid Deposition and Improves the Homeostasis of Oxidative Stress Through a Sirtuin-1 (SIRT1) Independent Manner. Mol Nutr Food Res. 2019;:e1900343 pubmed publisher
Yan Z, Zhu S, Wang H, Wang L, Du T, Ye Z, et al. MOTS-c inhibits Osteolysis in the Mouse Calvaria by affecting osteocyte-osteoclast crosstalk and inhibiting inflammation. Pharmacol Res. 2019;147:104381 pubmed publisher
Cui X, Zhang Y, Wang Z, Yu J, Kong Z, Ruzic L. High-intensity interval training changes the expression of muscle RING-finger protein-1 and muscle atrophy F-box proteins and proteins involved in the mechanistic target of rapamycin pathway and autophagy in rat skeletal muscle. Exp Physiol. 2019;: pubmed publisher
Xu W, Yang R, Zheng H, Yu W, Zheng X, Li B, et al. PGC-1α acts as an mediator of Sirtuin2 to protect annulus fibrosus from apoptosis induced by oxidative stress through restraining mitophagy. Int J Biol Macromol. 2019;136:1007-1017 pubmed publisher
Shen X, Chen Y, Zhang J, Yan X, Liu W, Guo Y, et al. Low-dose PCB126 compromises circadian rhythms associated with disordered glucose and lipid metabolism in mice. Environ Int. 2019;128:146-157 pubmed publisher
Iershov A, Nemazanyy I, Alkhoury C, Girard M, Barth E, Cagnard N, et al. The class 3 PI3K coordinates autophagy and mitochondrial lipid catabolism by controlling nuclear receptor PPARα. Nat Commun. 2019;10:1566 pubmed publisher
Li L, Zhang H, Yao Y, Yang Z, Ma H. (-)-Hydroxycitric Acid Suppresses Lipid Droplet Accumulation and Accelerates Energy Metabolism via Activation of the Adiponectin-AMPK Signaling Pathway in Broiler Chickens. J Agric Food Chem. 2019;67:3188-3197 pubmed publisher
Lei P, Tian S, Teng C, Huang L, Liu X, Wang J, et al. Sulforaphane Improves Lipid Metabolism by Enhancing Mitochondrial Function and Biogenesis In Vivo and In Vitro. Mol Nutr Food Res. 2019;63:e1800795 pubmed publisher
Liu B, Jin J, Zhang Z, Zuo L, Jiang M, Xie C. Shikonin exerts antitumor activity by causing mitochondrial dysfunction in hepatocellular carcinoma through PKM2-AMPK-PGC1α signaling pathway. Biochem Cell Biol. 2018;:1-9 pubmed publisher
Dervishi I, Gozutok O, Murnan K, Gautam M, Heller D, Bigio E, et al. Protein-protein interactions reveal key canonical pathways, upstream regulators, interactome domains, and novel targets in ALS. Sci Rep. 2018;8:14732 pubmed publisher
Shen Y, Wu L, Wang J, Wu X, Zhang X. The Role of Mitochondria in Methamphetamine-induced inhibitory effects on osteogenesis of Mesenchymal Stem Cells. Eur J Pharmacol. 2018;826:56-65 pubmed publisher
Liu M, Zhu H, Dai Y, Pan H, Li N, Wang L, et al. Zinc-α2-Glycoprotein Is Associated with Obesity in Chinese People and HFD-Induced Obese Mice. Front Physiol. 2018;9:62 pubmed publisher
product information
CatalogNo :
66369-1-Ig
AntigenName :
PGC1a
Package :
150UL
Price :
299 USD
Exsists20ul :
20ul trial size available
FullName :
peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
Immunogen :
Peptide
Species :
chicken, human, mouse, rat, swine
Host :
Mouse
IsConjugated :
Unconjugated
AntigenSpecies :
human
CloneNo :
1C1B2
Application :
WB, IHC, IF, ELISA
Clonlity :
Monoclonal
IsoType :
IgG1
Synonyms :
LEM6, Ligand effect modulator 6, PGC 1 alpha, PGC 1(alpha), PGC 1v, PGC1, PGC1A, PGC-1α, PPAR gamma coactivator 1 alpha, PPARGC 1 alpha, PPARGC1, PPARGC1A
PrimaryOrSecondary :
Primary
AntibodyBuffer :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
GenBankNo :
NM_013261
PurifyMethod :
Protein G purification
NewAb :
False
IsSellable :
True
Feature :
siRNA
AppTiter :
IF 1:200 ; WB 1:10000 ;
company information
Proteintech Group
2201 W. Campbell Park Dr. STE12
Chicago, IL 60612
Proteintech@ptglab.com
https://www.ptglab.com
1-312-455-8498
headquarters: USA
At Proteintech, we produce every single antibody we sell; we do not rely on or supply to any other antibody providers: our products are unique and we are 100% accountable for each one. We realize this accountability by validating in-house, providing extensive technical support and guaranteeing your success: in addition to helping you troubleshoot your experiment, we will offer you a full cash refund if you are in any way dissatisfied. We can guarantee satisfaction because we have confidence in our products, confidence cultivated by the science behind our antibodies: we make them using as much of the native protein as possible, and purifying them using affinity purification with the original antigen. We carry out antibody production over a 102-day period, which allows for better antigen fitting to MHC molecules and affinity maturation in the host. This approach results in higher affinity antibodies with greater sensitivity, which you can use in any application and in multiple species.
You can only buy Proteintech antibodies directly from Proteintech or via one of its approved distributors — when you receive your antibody and see the Proteintech logo on the vial, know that you hold something that is truly unique.