This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Proteintech Group
product type :
antibody
product name :
Caspase 9/p35/p10
catalog :
66169-1-Ig
quantity :
150UL
price :
299 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
1B7G2
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation
citations: 23
Published Application/Species/Sample/DilutionReference
  • western blot; human; 1:1000; loading ...; fig 1f
Feng J, Wu L, Ji J, Chen K, Yu Q, Zhang J, et al. PKM2 is the target of proanthocyanidin B2 during the inhibition of hepatocellular carcinoma. J Exp Clin Cancer Res. 2019;38:204 pubmed publisher
  • western blot; human; 1:1000; fig 3
Huang Q, Zhan L, Cao H, Li J, Lyu Y, Guo X, et al. Increased mitochondrial fission promotes autophagy and hepatocellular carcinoma cell survival through the ROS-modulated coordinated regulation of the NFKB and TP53 pathways. Autophagy. 2016;12:999-1014 pubmed publisher
  • western blot; human; fig 5
Chen J, Wang C, Lan W, Huang C, Lin M, Wang Z, et al. Gliotoxin Inhibits Proliferation and Induces Apoptosis in Colorectal Cancer Cells. Mar Drugs. 2015;13:6259-73 pubmed publisher
Yu Q, Xin H, Qiu R, Deng Z, Deng F, Yan Z. Niclosamide: drug repurposing for human chondrosarcoma treatment via the caspase-dependent mitochondrial apoptotic pathway. Am J Transl Res. 2020;12:3688-3701 pubmed
Feng Q, Bian X, Liu X, Wang Y, Zhou H, Ma X, et al. Intracellular expression of arginine deiminase activates the mitochondrial apoptosis pathway by inhibiting cytosolic ferritin and inducing chromatin autophagy. BMC Cancer. 2020;20:665 pubmed publisher
Liu W, Xiao K, Ren L, Sui Y, Chen J, Zhang T, et al. Leukemia cells apoptosis by a newly discovered heterogeneous polysaccharide from Angelica sinensis (Oliv.) Diels. Carbohydr Polym. 2020;241:116279 pubmed publisher
Ji J, Wu L, Feng J, Mo W, Wu J, Yu Q, et al. Cafestol preconditioning attenuates apoptosis and autophagy during hepatic ischemia-reperfusion injury by inhibiting ERK/PPARγ pathway. Int Immunopharmacol. 2020;84:106529 pubmed publisher
Bai L, Liang J, Li L, Li E. Downregulation of MiD49 contributes to tumor growth and metastasis of human pancreatic cancer. Oncol Rep. 2020;43:1208-1220 pubmed publisher
Zhao Y, Guo Y, Chen Y, Liu S, Wu N, Jia D. Curculigoside attenuates myocardial ischemia‑reperfusion injury by inhibiting the opening of the mitochondrial permeability transition pore. Int J Mol Med. 2020;45:1514-1524 pubmed publisher
Almoiliqy M, Wen J, Xu B, Sun Y, Lian M, Li Y, et al. Cinnamaldehyde protects against rat intestinal ischemia/reperfusion injuries by synergistic inhibition of NF-κB and p53. Acta Pharmacol Sin. 2020;41:1208-1222 pubmed publisher
Zhang Q, Li J, Peng S, Zhang Y, Qiao Y. Rosmarinic Acid as a Candidate in a Phenotypic Profiling Cardio-/Cytotoxicity Cell Model Induced by Doxorubicin. Molecules. 2020;25: pubmed publisher
Mo D, Tian W, Zhang H, Feng Y, Sun Y, Quan W, et al. Cardioprotective effects of galectin-3 inhibition against ischemia/reperfusion injury. Eur J Pharmacol. 2019;863:172701 pubmed publisher
Li S, Jiang W, Xiao W, Li K, Zhang Y, Guo X, et al. KMT2D deficiency enhances the anti-cancer activity of L48H37 in pancreatic ductal adenocarcinoma. World J Gastrointest Oncol. 2019;11:599-621 pubmed publisher
Liao X, Fan Y, Hou J, Chen X, Xu X, Yang Y, et al. Identification of Chaetocin as a Potent non-ROS-mediated Anticancer Drug Candidate for Gastric Cancer. J Cancer. 2019;10:3678-3690 pubmed publisher
Deng J, Feng J, Liu T, Lu X, Wang W, Liu N, et al. Beraprost sodium preconditioning prevents inflammation, apoptosis, and autophagy during hepatic ischemia-reperfusion injury in mice via the P38 and JNK pathways. Drug Des Devel Ther. 2018;12:4067-4082 pubmed publisher
Xu H, Li Y, Han B, Li Z, Wang B, Jiang P, et al. Anti-breast-Cancer Activity Exerted by β-Sitosterol-d-glucoside from Sweet Potato via Upregulation of MicroRNA-10a and via the PI3K-Akt Signaling Pathway. J Agric Food Chem. 2018;66:9704-9718 pubmed publisher
Li X, Qiu Z, Jin Q, Chen G, Guo M. Cell Cycle Arrest and Apoptosis in HT-29 Cells Induced by Dichloromethane Fraction From Toddalia asiatica (L.) Lam. Front Pharmacol. 2018;9:629 pubmed publisher
Feng J, Niu P, Chen K, Wu L, Liu T, Xu S, et al. Salidroside mediates apoptosis and autophagy inhibition in concanavalin A-induced liver injury. Exp Ther Med. 2018;15:4599-4614 pubmed publisher
Serrano B, Szydlo H, Alfandari D, Hardy J. Active site-adjacent phosphorylation at Tyr-397 by c-Abl kinase inactivates caspase-9. J Biol Chem. 2017;292:21352-21365 pubmed publisher
Fu W, Li X, Lu X, Zhang L, Li R, Zhang N, et al. A novel acridine derivative, LS-1-10 inhibits autophagic degradation and triggers apoptosis in colon cancer cells. Cell Death Dis. 2017;8:e3086 pubmed publisher
Ren W, Wang P, Yan J, Liu G, Zeng B, Hussain T, et al. Melatonin alleviates weanling stress in mice: Involvement of intestinal microbiota. J Pineal Res. 2018;64: pubmed publisher
Ji L, Liu F, Jing Z, Huang Q, Zhao Y, Cao H, et al. MICU1 Alleviates Diabetic Cardiomyopathy Through Mitochondrial Ca2+-Dependent Antioxidant Response. Diabetes. 2017;66:1586-1600 pubmed publisher
Hu L, Su C, Song X, Shi Q, Fu J, Xia X, et al. Tetrachlorobenzoquinone triggers the cleavage of Bid and promotes the cross-talk of extrinsic and intrinsic apoptotic signalings in pheochromocytoma (PC) 12 cells. Neurotoxicology. 2015;49:149-57 pubmed publisher
product information
CatalogNo :
66169-1-Ig
AntigenName :
Caspase 9/p35/p10
Package :
150UL
Price :
299 USD
Exsists20ul :
20ul trial size available
FullName :
caspase 9, apoptosis-related cysteine peptidase
Immunogen :
Recombinant Protein
Species :
human, mouse, rat
Host :
Mouse
IsConjugated :
Unconjugated
AntigenSpecies :
human
CloneNo :
1B7G2
Application :
WB, IP, IHC, IF, ELISA
Clonlity :
Monoclonal
IsoType :
IgG2b
Synonyms :
APAF 3, APAF3, Apoptotic protease Mch 6, CASP 9, CASP9, Caspase 9, Caspase 9/p35/p10, CASPASE 9c, Caspase9, Caspase-9, ICE LAP6, ICE like apoptotic protease 6, MCH6
PrimaryOrSecondary :
Primary
AntibodyBuffer :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
GenBankNo :
BC002452
Category :
Apoptosis;Binding Proteins;Cytoskeleton/Scaffold Proteins;Metabolism;
PurifyMethod :
Protein A purification
NewAb :
False
IsSellable :
True
AppTiter :
IF 1:100 ; IHC 1:200 ; IP 1:500 ; WB 1:1000 ;
company information
Proteintech Group
2201 W. Campbell Park Dr. STE12
Chicago, IL 60612
Proteintech@ptglab.com
https://www.ptglab.com
1-312-455-8498
headquarters: USA
At Proteintech, we produce every single antibody we sell; we do not rely on or supply to any other antibody providers: our products are unique and we are 100% accountable for each one. We realize this accountability by validating in-house, providing extensive technical support and guaranteeing your success: in addition to helping you troubleshoot your experiment, we will offer you a full cash refund if you are in any way dissatisfied. We can guarantee satisfaction because we have confidence in our products, confidence cultivated by the science behind our antibodies: we make them using as much of the native protein as possible, and purifying them using affinity purification with the original antigen. We carry out antibody production over a 102-day period, which allows for better antigen fitting to MHC molecules and affinity maturation in the host. This approach results in higher affinity antibodies with greater sensitivity, which you can use in any application and in multiple species.
You can only buy Proteintech antibodies directly from Proteintech or via one of its approved distributors — when you receive your antibody and see the Proteintech logo on the vial, know that you hold something that is truly unique.