This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Proteintech Group
product type :
antibody
product name :
LC3A/B
catalog :
66139-1-Ig
quantity :
150
price :
279 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
2B2B5
reactivity :
human, mouse, rat
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section
citations: 13
Published Application/Species/DilutionReference
  • immunohistochemistry - paraffin section; human; 1:50; fig 4d
  • western blot; human; 1:1000; fig 4c
Yang X, Qi L, Lin F, Ou Z. The role of the chemokine receptor XCR1 in breast cancer cells.. Breast Cancer (Dove Med Press). 2017;9:227-236 pubmed publisher
Song Z, Shah S, Yang W, Dong H, Yang L, Zhou X, et al. Downregulation of the Repressor Element 1-Silencing Transcription Factor (REST) Is Associated with Akt-mTOR and Wnt-β-Catenin Signaling in Prion Diseases Models.. Front Mol Neurosci. 2017;10:128 pubmed publisher
Song Z, Yang W, Zhou X, Yang L, Zhao D. Lithium alleviates neurotoxic prion peptide-induced synaptic damage and neuronal death partially by the upregulation of nuclear target REST and the restoration of Wnt signaling.. Neuropharmacology. 2017;0: pubmed publisher
Dai C, Tang S, Velkov T, Xiao X. Colistin-Induced Apoptosis of Neuroblastoma-2a Cells Involves the Generation of Reactive Oxygen Species, Mitochondrial Dysfunction, and Autophagy. Mol Neurobiol. 2016;53:4685-700 pubmed publisher
Yu J, Chen C, Xu T, Yan M, Xue B, Wang Y, et al. Pseudolaric acid B activates autophagy in MCF-7 human breast cancer cells to prevent cell death. Oncol Lett. 2016;11:1731-1737 pubmed
Yuan X, Du J, Hua S, Zhang H, Gu C, Wang J, et al. Suppression of autophagy augments the radiosensitizing effects of STAT3 inhibition on human glioma cells. Exp Cell Res. 2015;330:267-76 pubmed publisher
Wu P, Zhu X, Jin W, Hao S, Liu Q, Zhang L. Oxaliplatin triggers necrosis as well as apoptosis in gastric cancer SGC-7901 cells. Biochem Biophys Res Commun. 2015;460:183-90 pubmed publisher
Sun Y, Liu Z, Zou X, Lan Y, Sun X, Wang X, et al. Mechanisms underlying 3-bromopyruvate-induced cell death in colon cancer. J Bioenerg Biomembr. 2015;47:319-29 pubmed publisher
Li Z, Wang Y, Newton I, Zhang L, Ji P, Li Z. GRP78 is implicated in the modulation of tumor aerobic glycolysis by promoting autophagic degradation of IKKβ. Cell Signal. 2015;27:1237-45 pubmed publisher
Yu J, Ren P, Zhong T, Wang Y, Yan M, Xue B, et al. Pseudolaric acid B inhibits proliferation in SW579 human thyroid squamous cell carcinoma. Mol Med Rep. 2015;12:7195-202 pubmed publisher
Gao L, Wang Y, Xu Z, Li X, Wu J, Liu S, et al. SZC017, a novel oleanolic acid derivative, induces apoptosis and autophagy in human breast cancer cells. Apoptosis. 2015;20:1636-50 pubmed publisher
Wang L, Cheng X, Huang C, Huang B, Liang Q. Rapamycin protects cardiomyocytes against anoxia/reoxygenation injury by inducing autophagy through the PI3k/Akt pathway. J Huazhong Univ Sci Technolog Med Sci. 2015;35:10-5 pubmed publisher
Yang X, Lin F, Guo Y, Shao Z, Ou Z. Gemcitabine resistance in breast cancer cells regulated by PI3K/AKT-mediated cellular proliferation exerts negative feedback via the MEK/MAPK and mTOR pathways. Onco Targets Ther. 2014;7:1033-42 pubmed
product information
Catalog Number :
66139-1-Ig
Item Name :
LC3A/B
Quantity / Package Size :
150
20ul trial size available :
20ul trial size available
FullName :
microtubule-associated protein 1 light chain 3 alpha
Antigen :
Fusion Protein
Species Reactivity :
hamster, human, mouse, pig, rat
Host Species :
Mouse
Conjugate :
Unconjugated
Antigen Species :
human
Clone Number :
2B2B5
Applications :
ELISA, FC, IF, IHC, WB
Type :
Monoclonal
Isotype :
IgG1
Antigen Synonyms :
LC3, LC3A, LC3A/B, LC3B, MAP1A/MAP1B LC3 A, MAP1A/MAP1B light chain 3 A, MAP1ALC3, MAP1BLC3, MAP1LC3A, MAP1LC3A/B, MAP1LC3B
Primary or Secondary? :
Primary
AntibodyBuffer :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
GenBankNo :
NM_032514
Category :
Apoptosis;Binding Proteins;Cytoskeleton/Scaffold Proteins;Membrane Proteins;Metabolism;Neurology;
Price :
279 USD
Form/Purification :
Protein G purification
PMID :
24966685, 25220423, 25673186, 25748049, 25767076, 26054380, 26316077, 26407982, 26460192, 26998069, 28408852, 28515679, 28545972
IsSellable :
1
AppTiter :
IHC 1:50 ; WB 1:1000 ; FC 1:0 ;
company information
Proteintech Group
2201 W. Campbell Park Dr. STE12
Chicago, IL 60612
Proteintech@ptglab.com
www.ptglab.com
1-312-455-8498
headquarters: USA
At Proteintech, we produce every single antibody we sell; we do not rely on or supply to any other antibody providers: our products are unique and we are 100% accountable for each one. We realize this accountability by validating in-house, providing extensive technical support and guaranteeing your success: in addition to helping you troubleshoot your experiment, we will offer you a full cash refund if you are in any way dissatisfied. We can guarantee satisfaction because we have confidence in our products, confidence cultivated by the science behind our antibodies: we make them using as much of the native protein as possible, and purifying them using affinity purification with the original antigen. We carry out antibody production over a 102-day period, which allows for better antigen fitting to MHC molecules and affinity maturation in the host. This approach results in higher affinity antibodies with greater sensitivity, which you can use in any application and in multiple species.
You can only buy Proteintech antibodies directly from Proteintech or via one of its approved distributors — when you receive your antibody and see the Proteintech logo on the vial, know that you hold something that is truly unique.