This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Proteintech Group
product type :
antibody
product name :
IFITM2-specific
catalog :
66137-1-Ig
quantity :
150UL
price :
299 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
3D5F7
reactivity :
human
application :
western blot, ELISA, flow cytometry, western blot knockout validation
citations: 9
Published Application/Species/Sample/DilutionReference
  • western blot knockout validation; human; fig 5a
Wu X, Dao Thi V, Huang Y, Billerbeck E, Saha D, Hoffmann H, et al. Intrinsic Immunity Shapes Viral Resistance of Stem Cells. Cell. 2018;172:423-438.e25 pubmed publisher
  • western blot; human; loading ...; fig 4g
Shi G, OZOG S, Torbett B, Compton A. mTOR inhibitors lower an intrinsic barrier to virus infection mediated by IFITM3. Proc Natl Acad Sci U S A. 2018;115:E10069-E10078 pubmed publisher
  • western blot; human; 1 ug/ml; fig s7c
Wu W, Grotefend C, Tsai M, Wang Y, Radic V, Eoh H, et al. ?20 IFITM2 differentially restricts X4 and R5 HIV-1. Proc Natl Acad Sci U S A. 2017;114:7112-7117 pubmed publisher
  • flow cytometry; human; loading ...; fig ev1a
Monel B, Compton A, Bruel T, Amraoui S, Burlaud Gaillard J, Roy N, et al. Zika virus induces massive cytoplasmic vacuolization and paraptosis-like death in infected cells. EMBO J. 2017;36:1653-1668 pubmed publisher
Gobillot T, Humes D, Sharma A, Kikawa C, Overbaugh J. The Robust Restriction of Zika Virus by Type-I Interferon in A549 Cells Varies by Viral Lineage and Is Not Determined by IFITM3. Viruses. 2020;12: pubmed publisher
Spence J, He R, Hoffmann H, Das T, Thinon E, Rice C, et al. IFITM3 directly engages and shuttles incoming virus particles to lysosomes. Nat Chem Biol. 2019;15:259-268 pubmed publisher
Lee W, Fu R, Liang C, Sloan R. IFITM proteins inhibit HIV-1 protein synthesis. Sci Rep. 2018;8:14551 pubmed publisher
Roesch F, OhAinle M, Emerman M. A CRISPR screen for factors regulating SAMHD1 degradation identifies IFITMs as potent inhibitors of lentiviral particle delivery. Retrovirology. 2018;15:26 pubmed publisher
Zhu X, He Z, Yuan J, Wen W, Huang X, Hu Y, et al. IFITM3-containing exosome as a novel mediator for anti-viral response in dengue virus infection. Cell Microbiol. 2015;17:105-18 pubmed publisher
product information
CatalogNo :
66137-1-Ig
AntigenName :
IFITM2-specific
Package :
150UL
Price :
299 USD
Exsists20ul :
20ul trial size available
FullName :
interferon induced transmembrane protein 2 (1-8D)
Immunogen :
Fusion Protein
Species :
human
Host :
Mouse
IsConjugated :
Unconjugated
AntigenSpecies :
human
CloneNo :
3D5F7
Application :
WB, FC, ELISA
Clonlity :
Monoclonal
IsoType :
IgG1
Synonyms :
DSPA2c, IFITM2
PrimaryOrSecondary :
Primary
AntibodyBuffer :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
GenBankNo :
NM_006435
Category :
Binding Proteins;Cell Cycle;Immunology;Membrane Proteins;
PurifyMethod :
Protein G purification
NewAb :
False
IsSellable :
True
Feature :
siRNA
AppTiter :
FC 1:0 ; WB 1:1000 ;
company information
Proteintech Group
2201 W. Campbell Park Dr. STE12
Chicago, IL 60612
Proteintech@ptglab.com
https://www.ptglab.com
1-312-455-8498
headquarters: USA
At Proteintech, we produce every single antibody we sell; we do not rely on or supply to any other antibody providers: our products are unique and we are 100% accountable for each one. We realize this accountability by validating in-house, providing extensive technical support and guaranteeing your success: in addition to helping you troubleshoot your experiment, we will offer you a full cash refund if you are in any way dissatisfied. We can guarantee satisfaction because we have confidence in our products, confidence cultivated by the science behind our antibodies: we make them using as much of the native protein as possible, and purifying them using affinity purification with the original antigen. We carry out antibody production over a 102-day period, which allows for better antigen fitting to MHC molecules and affinity maturation in the host. This approach results in higher affinity antibodies with greater sensitivity, which you can use in any application and in multiple species.
You can only buy Proteintech antibodies directly from Proteintech or via one of its approved distributors — when you receive your antibody and see the Proteintech logo on the vial, know that you hold something that is truly unique.