This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Proteintech Group
product type :
antibody
product name :
APOL1-Specific
catalog :
66124-1-Ig
quantity :
150UL
price :
299 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
1G12D11
reactivity :
hamsters, human
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry
citations: 7
Published Application/Species/Sample/DilutionReference
  • western blot; human; 1:2000; loading ...; fig 1b, 4s1a
  • immunocytochemistry; hamsters; 1:800; loading ...; fig 5a
Giovinazzo J, Thomson R, Khalizova N, Zager P, Malani N, Rodriguez Boulan E, et al. Apolipoprotein L-1 renal risk variants form active channels at the plasma membrane driving cytotoxicity. elife. 2020;9: pubmed publisher
  • western blot; human; loading ...; fig 1c
Jha A, Kumar V, Haque S, Ayasolla K, Saha S, Lan X, et al. Alterations in plasma membrane ion channel structures stimulate NLRP3 inflammasome activation in APOL1 risk milieu. FEBS J. 2019;: pubmed publisher
Datta S, Kataria R, Zhang J, Moore S, Petitpas K, Mohamed A, et al. Kidney Disease-Associated APOL1 Variants Have Dose-Dependent, Dominant Toxic Gain-of-Function. J Am Soc Nephrol. 2020;31:2083-2096 pubmed publisher
Kumar V, Ayasolla K, Jha A, Mishra A, Vashistha H, Lan X, et al. Disrupted APOL1-miR193a Axis Dedifferentiates Podocytes through Autophagy Blockade in APOL1 Risk Milieu. Am J Physiol Cell Physiol. 2019;: pubmed publisher
Kumar V, Paliwal N, Ayasolla K, Vashistha H, Jha A, Chandel N, et al. Disruption of APOL1-miR193a Axis Induces Disorganization of Podocyte Actin Cytoskeleton. Sci Rep. 2019;9:3582 pubmed publisher
Kumar V, Vashistha H, Lan X, Chandel N, Ayasolla K, Shoshtari S, et al. Role of Apolipoprotein L1 in Human Parietal Epithelial Cell Transition. Am J Pathol. 2018;188:2508-2528 pubmed publisher
Wen H, Kumar V, Lan X, Shoshtari S, Eng J, Zhou X, et al. APOL1 risk variants cause podocytes injury through enhancing endoplasmic reticulum stress. Biosci Rep. 2018;38: pubmed publisher
product information
CatalogNo :
66124-1-Ig
AntigenName :
APOL1-Specific
Package :
150UL
Price :
299 USD
FullName :
apolipoprotein L, 1
Immunogen :
Fusion Protein
Species :
human, mouse
Host :
Mouse
IsConjugated :
Unconjugated
AntigenSpecies :
human
CloneNo :
1G12D11
Application :
WB, IP, IHC, IF, FC, ELISA
Clonlity :
Monoclonal
IsoType :
IgG2a
Synonyms :
APO L, APOL, APOL I, APOL1, Apolipoprotein L, Apolipoprotein L I, apolipoprotein L, 1, Apolipoprotein L1
PrimaryOrSecondary :
Primary
AntibodyBuffer :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
GenBankNo :
BC017331
Category :
Binding Proteins;Cytoskeleton/Scaffold Proteins;Metabolism;Transport/Trafficking;
PurifyMethod :
Protein A purification
NewAb :
False
IsSellable :
True
Feature :
siRNA
AppTiter :
FC 1:0 ; IF 1:100 ; IHC 1:500 ; IP 1:10000 ; WB 1:400000 ;
company information
Proteintech Group
2201 W. Campbell Park Dr. STE12
Chicago, IL 60612
Proteintech@ptglab.com
https://www.ptglab.com
1-312-455-8498
headquarters: USA
At Proteintech, we produce every single antibody we sell; we do not rely on or supply to any other antibody providers: our products are unique and we are 100% accountable for each one. We realize this accountability by validating in-house, providing extensive technical support and guaranteeing your success: in addition to helping you troubleshoot your experiment, we will offer you a full cash refund if you are in any way dissatisfied. We can guarantee satisfaction because we have confidence in our products, confidence cultivated by the science behind our antibodies: we make them using as much of the native protein as possible, and purifying them using affinity purification with the original antigen. We carry out antibody production over a 102-day period, which allows for better antigen fitting to MHC molecules and affinity maturation in the host. This approach results in higher affinity antibodies with greater sensitivity, which you can use in any application and in multiple species.
You can only buy Proteintech antibodies directly from Proteintech or via one of its approved distributors — when you receive your antibody and see the Proteintech logo on the vial, know that you hold something that is truly unique.