This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Proteintech Group
product type :
antibody
product name :
Caspase 8/p43/p18
catalog :
66093-1-Ig
quantity :
150UL
price :
299 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
2B9H8
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation
citations: 29
Published Application/Species/Sample/DilutionReference
  • western blot; human; 1:1000; loading ...; fig 1a
Zou X, Zhang D, Song Y, Liu S, Long Q, Yao L, et al. HRG switches TNFR1-mediated cell survival to apoptosis in Hepatocellular Carcinoma. Theranostics. 2020;10:10434-10447 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 8c
Ding M, Weng C, Fan S, Cao Q, Lu Z. Purkinje Cell Degeneration and Motor Coordination Deficits in a New Mouse Model of Autosomal Recessive Spastic Ataxia of Charlevoix-Saguenay. Front Mol Neurosci. 2017;10:121 pubmed publisher
Zhu J, Yang L, Zhang Q, Meng J, Lu Z, Rong R. Autophagy Induced by Simian Retrovirus Infection Controls Viral Replication and Apoptosis of Jurkat T Lymphocytes. Viruses. 2020;12: pubmed publisher
Zeng N, Zhang Z, Jiang H, Li R, Chang C, Wang F, et al. LncRNA-241 inhibits 1,2-Dichloroethane-induced hepatic apoptosis. Toxicol In Vitro. 2019;61:104650 pubmed publisher
Li S, Jiang W, Xiao W, Li K, Zhang Y, Guo X, et al. KMT2D deficiency enhances the anti-cancer activity of L48H37 in pancreatic ductal adenocarcinoma. World J Gastrointest Oncol. 2019;11:599-621 pubmed publisher
Li D, Chen J, Ai Y, Gu X, Li L, Che D, et al. Estrogen-Related Hormones Induce Apoptosis by Stabilizing Schlafen-12 Protein Turnover. Mol Cell. 2019;: pubmed publisher
Yaron J, Chen H, Ambadapadi S, Zhang L, Tafoya A, Munk B, et al. Serp-2, a virus-derived apoptosis and inflammasome inhibitor, attenuates liver ischemia-reperfusion injury in mice. J Inflamm (Lond). 2019;16:12 pubmed publisher
Li S, Wang Y, Zhao H, Shao Y, Liu J, Xing M. Characterization, functional and signaling elucidation of pigeon (Columba livia) interferon-α: Knockdown p53 negatively modulates antiviral response. Dev Comp Immunol. 2019;90:29-40 pubmed publisher
Zhang G, Lu D, Duan S, Gao Y, Liu S, Hong Y, et al. Hydrogen Sulfide Alleviates Lipopolysaccharide-Induced Diaphragm Dysfunction in Rats by Reducing Apoptosis and Inflammation through ROS/MAPK and TLR4/NF-κB Signaling Pathways. Oxid Med Cell Longev. 2018;2018:9647809 pubmed publisher
Li X, Qiu Z, Jin Q, Chen G, Guo M. Cell Cycle Arrest and Apoptosis in HT-29 Cells Induced by Dichloromethane Fraction From Toddalia asiatica (L.) Lam. Front Pharmacol. 2018;9:629 pubmed publisher
Shao Y, Zhao H, Wang Y, Liu J, Li J, Luo L, et al. The apoptosis in arsenic-induced oxidative stress is associated with autophagy in the testis tissues of chicken. Poult Sci. 2018;97:3248-3257 pubmed publisher
Chen S, Lv X, Hu B, Zhao L, Li S, Li Z, et al. Critical contribution of RIPK1 mediated mitochondrial dysfunction and oxidative stress to compression-induced rat nucleus pulposus cells necroptosis and apoptosis. Apoptosis. 2018;23:299-313 pubmed publisher
Zhang Q, Li X, Chen Y, Chen J, Zhu J, Meng Y, et al. Wnt/β-catenin signaling mediates the suppressive effects of diallyl trisulfide on colorectal cancer stem cells. Cancer Chemother Pharmacol. 2018;81:969-977 pubmed publisher
Wu Z, Zhu Q, Yin Y, Kang D, Cao R, Tian Q, et al. Traditional Chinese Medicine CFF-1 induced cell growth inhibition, autophagy, and apoptosis via inhibiting EGFR-related pathways in prostate cancer. Cancer Med. 2018;7:1546-1559 pubmed publisher
Cao J, Liu X, Huang L, Wang L, Jiao X, Huo L. SUMO2 modification of Aurora B and its impact on follicular development and atresia in the mouse ovary. Int J Mol Med. 2018;41:3115-3126 pubmed publisher
Jia Y, Lu H, Peng Y, Zhang B, Gong X, Su J, et al. Oxyresveratrol prevents lipopolysaccharide/d-galactosamine-induced acute liver injury in mice. Int Immunopharmacol. 2018;56:105-112 pubmed publisher
Jung D, Khurana A, Roy D, Kalogera E, Bakkum Gamez J, Chien J, et al. Quinacrine upregulates p21/p27 independent of p53 through autophagy-mediated downregulation of p62-Skp2 axis in ovarian cancer. Sci Rep. 2018;8:2487 pubmed publisher
Hirsova P, Weng P, Salim W, Bronk S, Griffith T, Ibrahim S, et al. TRAIL Deletion Prevents Liver, but Not Adipose Tissue, Inflammation during Murine Diet-Induced Obesity. Hepatol Commun. 2017;1:648-662 pubmed publisher
Zhang Y, Gong F, Lu Z, Wang H, Cheng Y, Liu Z, et al. DHPAC, a novel synthetic microtubule destabilizing agent, possess high anti-tumor activity in vincristine-resistant oral epidermoid carcinoma in vitro and in vivo. Int J Biochem Cell Biol. 2017;93:1-11 pubmed publisher
Xu L, Zhang Y, Qu X, Che X, Guo T, Li C, et al. DR5-Cbl-b/c-Cbl-TRAF2 complex inhibits TRAIL-induced apoptosis by promoting TRAF2-mediated polyubiquitination of caspase-8 in gastric cancer cells. Mol Oncol. 2017;11:1733-1751 pubmed publisher
Ren W, Wang P, Yan J, Liu G, Zeng B, Hussain T, et al. Melatonin alleviates weanling stress in mice: Involvement of intestinal microbiota. J Pineal Res. 2018;64: pubmed publisher
Li D, Meng L, Xu T, Su Y, Liu X, Zhang Z, et al. RIPK1-RIPK3-MLKL-dependent necrosis promotes the aging of mouse male reproductive system. elife. 2017;6: pubmed publisher
Chen Y, Wang X, Zhang Q, Zhu J, Li Y, Xie C, et al. (-)-Epigallocatechin-3-Gallate Inhibits Colorectal Cancer Stem Cells by Suppressing Wnt/β-Catenin Pathway. Nutrients. 2017;9: pubmed publisher
Jiang Z, Song F, Li Y, Xue D, Zhao N, Zhang J, et al. Capsular Polysaccharide of Mycoplasma ovipneumoniae Induces Sheep Airway Epithelial Cell Apoptosis via ROS-Dependent JNK/P38 MAPK Pathways. Oxid Med Cell Longev. 2017;2017:6175841 pubmed publisher
Gong X, Yang Y, Huang L, Zhang Q, Wan R, Zhang P, et al. Antioxidation, anti-inflammation and anti-apoptosis by paeonol in LPS/d-GalN-induced acute liver failure in mice. Int Immunopharmacol. 2017;46:124-132 pubmed publisher
Liu X, Ding S, Shi P, Dietrich R, Märtlbauer E, Zhu K. Non-hemolytic enterotoxin of Bacillus cereus induces apoptosis in Vero cells. Cell Microbiol. 2017;19: pubmed publisher
Li J, Chen K, Li S, Liu T, Wang F, Xia Y, et al. Pretreatment with Fucoidan from Fucus vesiculosus Protected against ConA-Induced Acute Liver Injury by Inhibiting Both Intrinsic and Extrinsic Apoptosis. PLoS ONE. 2016;11:e0152570 pubmed publisher
Xu Y, Wu D, Fan Y, Li P, DU H, Shi J, et al. Novel Recombinant Protein FlaA N/C Protects against Radiation Injury via NF-κB Signaling. Radiat Res. 2016;185:77-86 pubmed publisher
Shan X, Tian L, Zhang Y, Wang X, Yan Q, Liu J. Ginsenoside Rg3 suppresses FUT4 expression through inhibiting NF-κB/p65 signaling pathway to promote melanoma cell death. Int J Oncol. 2015;47:701-9 pubmed publisher
product information
CatalogNo :
66093-1-Ig
AntigenName :
Caspase 8/p43/p18
Package :
150UL
Price :
299 USD
Exsists20ul :
20ul trial size available
FullName :
caspase 8, apoptosis-related cysteine peptidase
Immunogen :
Fusion Protein
Species :
chicken, human, monkey, mouse, rat, sheep
Host :
Mouse
IsConjugated :
Unconjugated
AntigenSpecies :
human
CloneNo :
2B9H8
Application :
WB, IP, IHC, IF, ELISA
Clonlity :
Monoclonal
IsoType :
IgG2b
Synonyms :
Apoptotic cysteine protease, Apoptotic protease Mch 5, Casp 8, CASP8, Caspase 8, Caspase 8/p18, Caspase8, FADD like ICE, FLICE, ICE like apoptotic protease 5, MACH, MCH5
PrimaryOrSecondary :
Primary
AntibodyBuffer :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
GenBankNo :
BC028223
Category :
Apoptosis;Binding Proteins;Cytoskeleton/Scaffold Proteins;Membrane Proteins;Metabolism;
PurifyMethod :
Protein A purification
NewAb :
False
IsSellable :
True
Feature :
siRNA
AppTiter :
IF 1:100 ; IHC 1:200 ; IP 1:500 ; WB 1:5000 ;
company information
Proteintech Group
2201 W. Campbell Park Dr. STE12
Chicago, IL 60612
Proteintech@ptglab.com
https://www.ptglab.com
1-312-455-8498
headquarters: USA
At Proteintech, we produce every single antibody we sell; we do not rely on or supply to any other antibody providers: our products are unique and we are 100% accountable for each one. We realize this accountability by validating in-house, providing extensive technical support and guaranteeing your success: in addition to helping you troubleshoot your experiment, we will offer you a full cash refund if you are in any way dissatisfied. We can guarantee satisfaction because we have confidence in our products, confidence cultivated by the science behind our antibodies: we make them using as much of the native protein as possible, and purifying them using affinity purification with the original antigen. We carry out antibody production over a 102-day period, which allows for better antigen fitting to MHC molecules and affinity maturation in the host. This approach results in higher affinity antibodies with greater sensitivity, which you can use in any application and in multiple species.
You can only buy Proteintech antibodies directly from Proteintech or via one of its approved distributors — when you receive your antibody and see the Proteintech logo on the vial, know that you hold something that is truly unique.