This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Proteintech Group
product type :
antibody
product name :
IFITM2/3
catalog :
66081-1-Ig
quantity :
150UL
price :
299 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
2E8D12
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, flow cytometry, western blot knockout validation
citations: 9
Published Application/Species/Sample/DilutionReference
  • western blot knockout validation; human; loading ...; fig s4c
  • immunocytochemistry; human; loading ...; fig s3c, 3c
Shi G, OZOG S, Torbett B, Compton A. mTOR inhibitors lower an intrinsic barrier to virus infection mediated by IFITM3. Proc Natl Acad Sci U S A. 2018;115:E10069-E10078 pubmed publisher
  • western blot; human; loading ...; fig s2b
Kühnl A, Musiol A, Heitzig N, Johnson D, Ehrhardt C, Grewal T, et al. Late Endosomal/Lysosomal Cholesterol Accumulation Is a Host Cell-Protective Mechanism Inhibiting Endosomal Escape of Influenza A Virus. MBio. 2018;9: pubmed publisher
Ahi Y, Yimer D, Shi G, Majdoul S, Rahman K, Rein A, et al. IFITM3 Reduces Retroviral Envelope Abundance and Function and Is Counteracted by glycoGag. MBio. 2020;11: pubmed publisher
Winkler M, Wrensch F, Bosch P, Knoth M, Schindler M, Gärtner S, et al. Analysis of IFITM-IFITM Interactions by a Flow Cytometry-Based FRET Assay. Int J Mol Sci. 2019;20: pubmed publisher
Buchrieser J, Degrelle S, Couderc T, Nevers Q, Disson O, Manet C, et al. IFITM proteins inhibit placental syncytiotrophoblast formation and promote fetal demise. Science. 2019;365:176-180 pubmed publisher
Wang B, Lam T, Soh M, Ye Z, Chen J, Ren E. Influenza A Virus Facilitates Its Infectivity by Activating p53 to Inhibit the Expression of Interferon-Induced Transmembrane Proteins. Front Immunol. 2018;9:1193 pubmed publisher
Xu Yang Z, Pei Yu B, Chuan Tao Y, Wei Y, Hong Wei M, Kang T, et al. Interferon-Induced Transmembrane Protein 3 Inhibits Hantaan Virus Infection, and Its Single Nucleotide Polymorphism rs12252 Influences the Severity of Hemorrhagic Fever with Renal Syndrome. Front Immunol. 2016;7:535 pubmed publisher
Compton A, Roy N, Porrot F, Billet A, Casartelli N, Yount J, et al. Natural mutations in IFITM3 modulate post-translational regulation and toggle antiviral specificity. EMBO Rep. 2016;17:1657-1671 pubmed
Xie M, Xuan B, Shan J, Pan D, Sun Y, Shan Z, et al. Human cytomegalovirus exploits interferon-induced transmembrane proteins to facilitate morphogenesis of the virion assembly compartment. J Virol. 2015;89:3049-61 pubmed publisher
product information
CatalogNo :
66081-1-Ig
AntigenName :
IFITM2/3
Package :
150UL
Price :
299 USD
Exsists20ul :
20ul trial size available
FullName :
interferon induced transmembrane protein 3 (1-8U)
Immunogen :
Fusion Protein
Species :
human
Host :
Mouse
IsConjugated :
Unconjugated
AntigenSpecies :
human
CloneNo :
2E8D12
Application :
WB, IHC, IF, FC, ELISA
Clonlity :
Monoclonal
IsoType :
IgG1
Synonyms :
1 8U, IFITM3, IP15
PrimaryOrSecondary :
Primary
AntibodyBuffer :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
GenBankNo :
BC070243
Category :
Cell Cycle;Immunology;Membrane Proteins;
PurifyMethod :
Protein A purification
NewAb :
False
IsSellable :
True
Feature :
siRNA
AppTiter :
FC 1:0 ; IF 1:25 ; IHC 1:50 ; WB 1:20000 ;
company information
Proteintech Group
2201 W. Campbell Park Dr. STE12
Chicago, IL 60612
Proteintech@ptglab.com
https://www.ptglab.com
1-312-455-8498
headquarters: USA
At Proteintech, we produce every single antibody we sell; we do not rely on or supply to any other antibody providers: our products are unique and we are 100% accountable for each one. We realize this accountability by validating in-house, providing extensive technical support and guaranteeing your success: in addition to helping you troubleshoot your experiment, we will offer you a full cash refund if you are in any way dissatisfied. We can guarantee satisfaction because we have confidence in our products, confidence cultivated by the science behind our antibodies: we make them using as much of the native protein as possible, and purifying them using affinity purification with the original antigen. We carry out antibody production over a 102-day period, which allows for better antigen fitting to MHC molecules and affinity maturation in the host. This approach results in higher affinity antibodies with greater sensitivity, which you can use in any application and in multiple species.
You can only buy Proteintech antibodies directly from Proteintech or via one of its approved distributors — when you receive your antibody and see the Proteintech logo on the vial, know that you hold something that is truly unique.