This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Proteintech Group
product type :
antibody
product name :
Bcl-XL
catalog :
66020-1-Ig
quantity :
150UL
price :
299 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
4C12A6
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, flow cytometry
citations: 7
Published Application/Species/Sample/DilutionReference
  • western blot; human; 1:1000; fig 4
Huang Q, Zhan L, Cao H, Li J, Lyu Y, Guo X, et al. Increased mitochondrial fission promotes autophagy and hepatocellular carcinoma cell survival through the ROS-modulated coordinated regulation of the NFKB and TP53 pathways. Autophagy. 2016;12:999-1014 pubmed publisher
Lin Y, Yu M, Fan T. Insights into mechanisms of pranoprofen-induced apoptosis and necroptosis in human corneal stromal cells. Toxicol Lett. 2020;320:9-18 pubmed publisher
Inoue K, Hatano K, Hanamatsu Y, Saigo C, Kito Y, Bunai K, et al. Pathobiological role of cleft palate transmembrane protein 1 family proteins in oral squamous cell carcinoma. J Cancer Res Clin Oncol. 2019;145:851-859 pubmed publisher
Li Y, Zhang J, Su L, Kellum J, Peng Z. Downregulation of TIMP2 attenuates sepsis-induced AKI through the NF-κb pathway. Biochim Biophys Acta Mol Basis Dis. 2019;1865:558-569 pubmed publisher
Su Y, Li X, Ma J, Zhao J, Liu S, Wang G, et al. Targeting PI3K, mTOR, ERK, and Bcl-2 signaling network shows superior antileukemic activity against AML ex vivo. Biochem Pharmacol. 2018;148:13-26 pubmed publisher
Ren T, Wang J, Zhang H, Yuan P, Zhu J, Wu Y, et al. MCUR1-Mediated Mitochondrial Calcium Signaling Facilitates Cell Survival of Hepatocellular Carcinoma via Reactive Oxygen Species-Dependent P53 Degradation. Antioxid Redox Signal. 2018;28:1120-1136 pubmed publisher
Zhang F, Liu B, Wang Z, Yu X, Ni Q, Yang W, et al. A novel regulatory mechanism of Pim-3 kinase stability and its involvement in pancreatic cancer progression. Mol Cancer Res. 2013;11:1508-20 pubmed publisher
product information
CatalogNo :
66020-1-Ig
AntigenName :
Bcl-XL
Package :
150UL
Price :
299 USD
Exsists20ul :
20ul trial size available
FullName :
BCL2-like 1
Immunogen :
Fusion Protein
Species :
human
Host :
Mouse
IsConjugated :
Unconjugated
AntigenSpecies :
human
CloneNo :
4C12A6
Application :
WB, IHC, IF, FC, ELISA
Clonlity :
Monoclonal
IsoType :
IgG2b
Synonyms :
Apoptosis regulator Bcl X, BCL2L1, Bcl-XL
PrimaryOrSecondary :
Primary
AntibodyBuffer :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
GenBankNo :
BC019307
Category :
Apoptosis;Binding Proteins;Cytoskeleton/Scaffold Proteins;Development;Membrane Proteins;Oncogene(s) and Tumor Suppressor(s);
PurifyMethod :
Protein A purification
NewAb :
False
IsSellable :
True
AppTiter :
FC 1:0 ; IF 1:25 ; IHC 1:600 ; WB 1:20000 ;
company information
Proteintech Group
2201 W. Campbell Park Dr. STE12
Chicago, IL 60612
Proteintech@ptglab.com
https://www.ptglab.com
1-312-455-8498
headquarters: USA
At Proteintech, we produce every single antibody we sell; we do not rely on or supply to any other antibody providers: our products are unique and we are 100% accountable for each one. We realize this accountability by validating in-house, providing extensive technical support and guaranteeing your success: in addition to helping you troubleshoot your experiment, we will offer you a full cash refund if you are in any way dissatisfied. We can guarantee satisfaction because we have confidence in our products, confidence cultivated by the science behind our antibodies: we make them using as much of the native protein as possible, and purifying them using affinity purification with the original antigen. We carry out antibody production over a 102-day period, which allows for better antigen fitting to MHC molecules and affinity maturation in the host. This approach results in higher affinity antibodies with greater sensitivity, which you can use in any application and in multiple species.
You can only buy Proteintech antibodies directly from Proteintech or via one of its approved distributors — when you receive your antibody and see the Proteintech logo on the vial, know that you hold something that is truly unique.