This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Proteintech Group
product type :
antibody
product name :
SIRT1
catalog :
60303-1-Ig
quantity :
150UL
price :
299 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
7F6G6
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation
citations: 7
Reference
Xu D, Liu L, Zhao Y, Yang L, Cheng J, Hua R, et al. Melatonin protects mouse testes from palmitic acid-induced lipotoxicity by attenuating oxidative stress and DNA damage in a SIRT1-dependent manner. J Pineal Res. 2020;:e12690 pubmed publisher
Yang H, Chen Y, Jiang Y, Wang D, Yan J, Zhou Z. TP53 mutation influences the efficacy of treatment of colorectal cancer cell lines with a combination of sirtuin inhibitors and chemotherapeutic agents. Exp Ther Med. 2020;20:1415-1422 pubmed publisher
Kwon I, Jang Y, Lee Y. Endurance Exercise-Induced Autophagy/Mitophagy Coincides with a Reinforced Anabolic State and Increased Mitochondrial Turnover in the Cortex of Young Male Mouse Brain. J Mol Neurosci. 2020;: pubmed publisher
Lai T, Wen X, Wu D, Su G, Gao Y, Chen C, et al. SIRT1 protects against urban particulate matter-induced airway inflammation. Int J Chron Obstruct Pulmon Dis. 2019;14:1741-1752 pubmed publisher
Xu B, Lang L, Li S, Guo J, Wang J, Yang H, et al. Microglia Activated by Excess Cortisol Induce HMGB1 Acetylation and Neuroinflammation in the Hippocampal DG Region of Mice Following Cold Exposure. Biomolecules. 2019;9: pubmed publisher
Le K, Chibaatar Daliv E, Wu S, Qian F, Ali A, Yu D, et al. SIRT1-regulated HMGB1 release is partially involved in TLR4 signal transduction: A possible anti-neuroinflammatory mechanism of resveratrol in neonatal hypoxic-ischemic brain injury. Int Immunopharmacol. 2019;75:105779 pubmed publisher
Pfister J, Ma C, D Mello S. Catalytic-independent neuroprotection by SIRT1 is mediated through interaction with HDAC1. PLoS ONE. 2019;14:e0215208 pubmed publisher
product information
CatalogNo :
60303-1-Ig
AntigenName :
SIRT1
Package :
150UL
Price :
299 USD
Exsists20ul :
20ul trial size available
FullName :
sirtuin (silent mating type information regulation 2 homolog) 1 (S. cerevisiae)
Immunogen :
Recombinant Protein
Species :
human, mouse
Host :
Mouse
IsConjugated :
Unconjugated
AntigenSpecies :
human
CloneNo :
7F6G6
Application :
WB, IP, IHC, IF, ELISA
Clonlity :
Monoclonal
IsoType :
IgG2b
Synonyms :
hSIR2, hSIRT1, SIR2 like protein 1, SIR2L1, SIRT1
PrimaryOrSecondary :
Primary
AntibodyBuffer :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
GenBankNo :
BC012499
Category :
Binding Proteins;Cell Cycle;Cytoskeleton/Scaffold Proteins;Development;Membrane Proteins;Metabolism;Neurology;
PurifyMethod :
Protein A purification
NewAb :
False
IsSellable :
True
Feature :
siRNA
AppTiter :
IF 1:100 ; IHC 1:500 ; IP 1:1000 ; WB 1:6000 ;
company information
Proteintech Group
2201 W. Campbell Park Dr. STE12
Chicago, IL 60612
Proteintech@ptglab.com
https://www.ptglab.com
1-312-455-8498
headquarters: USA
At Proteintech, we produce every single antibody we sell; we do not rely on or supply to any other antibody providers: our products are unique and we are 100% accountable for each one. We realize this accountability by validating in-house, providing extensive technical support and guaranteeing your success: in addition to helping you troubleshoot your experiment, we will offer you a full cash refund if you are in any way dissatisfied. We can guarantee satisfaction because we have confidence in our products, confidence cultivated by the science behind our antibodies: we make them using as much of the native protein as possible, and purifying them using affinity purification with the original antigen. We carry out antibody production over a 102-day period, which allows for better antigen fitting to MHC molecules and affinity maturation in the host. This approach results in higher affinity antibodies with greater sensitivity, which you can use in any application and in multiple species.
You can only buy Proteintech antibodies directly from Proteintech or via one of its approved distributors — when you receive your antibody and see the Proteintech logo on the vial, know that you hold something that is truly unique.