This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Proteintech Group
product type :
antibody
product name :
PTEN
catalog :
60300-1-Ig
quantity :
150UL
price :
299 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
5C10B6
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry
citations: 17
Published Application/Species/Sample/DilutionReference
  • western blot; human; loading ...; fig 4d
Yin Y, Wang X, Li T, Ren Q, Li L, Sun X, et al. MicroRNA-221 promotes breast cancer resistance to adriamycin via modulation of PTEN/Akt/mTOR signaling. Cancer Med. 2020;9:1544-1552 pubmed publisher
  • immunocytochemistry; human; loading ...; fig 6f
  • western blot; human; 1:500; loading ...; fig 5a
Guo Y, Pei X. Tetrandrine-Induced Autophagy in MDA-MB-231 Triple-Negative Breast Cancer Cell through the Inhibition of PI3K/AKT/mTOR Signaling. Evid Based Complement Alternat Med. 2019;2019:7517431 pubmed publisher
  • western blot; human; loading ...; fig 4a
He T, Liu Y, Zhao S, Liu H, Wang Z, Shi Y. Comprehensive assessment the expression of core elements related to IGFIR/PI3K pathway in granulosa cells of women with polycystic ovary syndrome. Eur J Obstet Gynecol Reprod Biol. 2019;233:134-140 pubmed publisher
Han L, Cao X, Chen Z, Guo X, Yang L, Zhou Y, et al. Overcoming cisplatin resistance by targeting the MTDH-PTEN interaction in ovarian cancer with sera derived from rats exposed to Guizhi Fuling wan extract. BMC Complement Med Ther. 2020;20:57 pubmed publisher
Shi Y, He Y, Zhou Y, Li H, Yang D, Li R, et al. LSD1 negatively regulates autophagy in myoblast cells by driving PTEN degradation. Biochem Biophys Res Commun. 2019;: pubmed publisher
Sun B, Zhao X, Ming J, Liu X, Liu D, Jiang C. Stepwise detection and evaluation reveal miR-10b and miR-222 as a remarkable prognostic pair for glioblastoma. Oncogene. 2019;38:6142-6157 pubmed publisher
Du T, Li H, Fan Y, Yuan L, Guo X, Zhu Q, et al. The deubiquitylase OTUD3 stabilizes GRP78 and promotes lung tumorigenesis. Nat Commun. 2019;10:2914 pubmed publisher
Vishnoi M, Boral D, Liu H, Sprouse M, Yin W, Goswami Sewell D, et al. Targeting USP7 Identifies a Metastasis-Competent State within Bone Marrow-Resident Melanoma CTCs. Cancer Res. 2018;78:5349-5362 pubmed publisher
Zhou B, Wei C, Zhang S, Zhang Z, Gao H. Matrine reversed multidrug resistance of breast cancer MCF-7/ADR cells through PI3K/AKT signaling pathway. J Cell Biochem. 2018;119:3885-3891 pubmed publisher
Zhang Y, Gong F, Lu Z, Wang H, Cheng Y, Liu Z, et al. DHPAC, a novel synthetic microtubule destabilizing agent, possess high anti-tumor activity in vincristine-resistant oral epidermoid carcinoma in vitro and in vivo. Int J Biochem Cell Biol. 2017;93:1-11 pubmed publisher
Zhang J, Li Z, Liu L, Wang Q, Li S, Chen D, et al. Long noncoding RNA TSLNC8 is a tumor suppressor that inactivates the interleukin-6/STAT3 signaling pathway. Hepatology. 2018;67:171-187 pubmed publisher
Tong L, Chu M, Yan B, Zhao W, Liu S, Wei W, et al. MTDH promotes glioma invasion through regulating miR-130b-ceRNAs. Oncotarget. 2017;8:17738-17749 pubmed publisher
Ying H, Qu D, Liu C, Ying T, Lv J, Jin S, et al. Chemoresistance is associated with Beclin-1 and PTEN expression in epithelial ovarian cancers. Oncol Lett. 2015;9:1759-1763 pubmed
Wu Q, He J, Mei W, Zhang Z, Wu X, Sun F. Arene ruthenium(ii) complex, a potent inhibitor against proliferation, migration and invasion of breast cancer cells, reduces stress fibers, focal adhesions and invadopodia. Metallomics. 2014;6:2204-12 pubmed publisher
Liu J, Xu D, Wang Q, Zheng D, Jiang X, Xu L. LPS induced miR-181a promotes pancreatic cancer cell migration via targeting PTEN and MAP2K4. Dig Dis Sci. 2014;59:1452-60 pubmed publisher
Liu S, Li L, Zhang Y, Zhang Y, Zhao Y, You X, et al. The oncoprotein HBXIP uses two pathways to up-regulate S100A4 in promotion of growth and migration of breast cancer cells. J Biol Chem. 2012;287:30228-39 pubmed publisher
Wen W, Ding J, Sun W, Fu J, Chen Y, Wu K, et al. Cyclin G1-mediated epithelial-mesenchymal transition via phosphoinositide 3-kinase/Akt signaling facilitates liver cancer progression. Hepatology. 2012;55:1787-98 pubmed publisher
product information
CatalogNo :
60300-1-Ig
AntigenName :
PTEN
Package :
150UL
Price :
299 USD
Exsists20ul :
20ul trial size available
FullName :
phosphatase and tensin homolog
Immunogen :
Recombinant Protein
Species :
human, mouse
Host :
Mouse
IsConjugated :
Unconjugated
AntigenSpecies :
human
CloneNo :
5C10B6
Application :
WB, IHC, IF, ELISA
Clonlity :
Monoclonal
IsoType :
IgG2a
Synonyms :
10q23del, BZS, MHAM, MMAC1, phosphatase and tensin homolog, PTEN, PTEN1, TEP1
PrimaryOrSecondary :
Primary
AntibodyBuffer :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
GenBankNo :
BC005821
Category :
Apoptosis;Cell Cycle;Cytoskeleton/Scaffold Proteins;Immunology;Metabolism;Neurology;Oncogene(s) and Tumor Suppressor(s);Signal transduction;
PurifyMethod :
Protein A purification
NewAb :
False
IsSellable :
True
AppTiter :
IHC 1:600 ; WB 1:2000 ;
company information
Proteintech Group
2201 W. Campbell Park Dr. STE12
Chicago, IL 60612
Proteintech@ptglab.com
https://www.ptglab.com
1-312-455-8498
headquarters: USA
At Proteintech, we produce every single antibody we sell; we do not rely on or supply to any other antibody providers: our products are unique and we are 100% accountable for each one. We realize this accountability by validating in-house, providing extensive technical support and guaranteeing your success: in addition to helping you troubleshoot your experiment, we will offer you a full cash refund if you are in any way dissatisfied. We can guarantee satisfaction because we have confidence in our products, confidence cultivated by the science behind our antibodies: we make them using as much of the native protein as possible, and purifying them using affinity purification with the original antigen. We carry out antibody production over a 102-day period, which allows for better antigen fitting to MHC molecules and affinity maturation in the host. This approach results in higher affinity antibodies with greater sensitivity, which you can use in any application and in multiple species.
You can only buy Proteintech antibodies directly from Proteintech or via one of its approved distributors — when you receive your antibody and see the Proteintech logo on the vial, know that you hold something that is truly unique.