This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Proteintech Group
product type :
antibody
product name :
TNF alpha
catalog :
60291-1-Ig
quantity :
150UL
price :
299 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
7B8A11
reactivity :
human, mouse, rat
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section
citations: 99
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - paraffin section; human; loading ...; fig 4e
Fu W, Wang W, Li H, Jiao Y, Weng J, Huo R, et al. High Dimensional Mass Cytometry Analysis Reveals Characteristics of the Immunosuppressive Microenvironment in Diffuse Astrocytomas. Front Oncol. 2020;10:78 pubmed publisher
  • western blot; mouse; loading ...; fig 4c
Feng F, Wang Z, Li R, Wu Q, Gu C, Xu Y, et al. Citrus alkaline extracts prevent fibroblast senescence to ameliorate pulmonary fibrosis via activation of COX-2. Biomed Pharmacother. 2019;112:108669 pubmed publisher
  • western blot; rat; 1:500; fig 1e
Wu J, Hu G, Lu Y, Zheng J, Chen J, Wang X, et al. Palmitic acid aggravates inflammation of pancreatic acinar cells by enhancing unfolded protein response induced CCAAT-enhancer-binding protein ?-CCAAT-enhancer-binding protein ? activation. Int J Biochem Cell Biol. 2016;79:181-193 pubmed publisher
  • western blot; mouse; fig 2
Wu W, Zhao L, Yang P, Zhou W, Li B, Moorhead J, et al. Inflammatory Stress Sensitizes the Liver to Atorvastatin-Induced Injury in ApoE-/- Mice. PLoS ONE. 2016;11:e0159512 pubmed publisher
  • western blot; mouse; 1:500; loading ...; fig 6f
Wang Y, Duan W, Wang W, Di Wen -, Liu Y, Liu Y, et al. scAAV9-VEGF prolongs the survival of transgenic ALS mice by promoting activation of M2 microglia and the PI3K/Akt pathway. Brain Res. 2016;1648:1-10 pubmed publisher
  • western blot; mouse; 1:800; loading ...; fig 3c
Lei X, Cui K, Liu Q, Zhang H, Li Z, Huang B, et al. Exogenous Estradiol Benzoate Induces Spermatogenesis Disorder through Influencing Apoptosis and Oestrogen Receptor Signalling Pathway. Reprod Domest Anim. 2016;51:75-84 pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 7g,7h,7i
Wang C, Li H, Luo C, Li Y, Zhang Y, Yun D, et al. The effect of maternal obesity on the expression and functionality of placental P-glycoprotein: Implications in the individualized transplacental digoxin treatment for fetal heart failure. Placenta. 2015;36:1138-47 pubmed publisher
Zhang W, Yu H, Lin Q, Liu X, Cheng Y, Deng B. Anti-inflammatory effect of resveratrol attenuates the severity of diabetic neuropathy by activating the Nrf2 pathway. Aging (Albany NY). 2021;13:10659-10671 pubmed publisher
Li A, Zhang N, Zhao Z, Chen Y, Zhang L. Overexpression of B7-H4 promotes renal cell carcinoma progression by recruiting tumor-associated neutrophils via upregulation of CXCL8. Oncol Lett. 2020;20:1535-1544 pubmed publisher
Zheng P, Tian X, Zhang W, Yang Z, Zhou J, Zheng J, et al. Rhein Suppresses Neuroinflammation via Multiple Signaling Pathways in LPS-Stimulated BV2 Microglia Cells. Evid Based Complement Alternat Med. 2020;2020:7210627 pubmed publisher
Albashari A, He Y, Zhang Y, Ali J, Lin F, Zheng Z, et al. Thermosensitive bFGF-Modified Hydrogel with Dental Pulp Stem Cells on Neuroinflammation of Spinal Cord Injury. ACS Omega. 2020;5:16064-16075 pubmed publisher
Zhou X, Liu Z, Ying K, Wang H, Liu P, Ji X, et al. WJ-39, an Aldose Reductase Inhibitor, Ameliorates Renal Lesions in Diabetic Nephropathy by Activating Nrf2 Signaling. Oxid Med Cell Longev. 2020;2020:7950457 pubmed publisher
Zhao H, Wang Y, Li B, Zheng T, Liu X, Hu B, et al. Role of Endoplasmic Reticulum Stress in Otitis Media. Front Genet. 2020;11:495 pubmed publisher
Fu W, Wang W, Li H, Jiao Y, Huo R, Yan Z, et al. Single-Cell Atlas Reveals Complexity of the Immunosuppressive Microenvironment of Initial and Recurrent Glioblastoma. Front Immunol. 2020;11:835 pubmed publisher
Yang X, Yang R, Chen M, Zhou Q, Zheng Y, Lu C, et al. KGF-2 and FGF-21 poloxamer 407 hydrogel coordinates inflammation and proliferation homeostasis to enhance wound repair of scalded skin in diabetic rats. BMJ Open Diabetes Res Care. 2020;8: pubmed publisher
Gao F, Zuo B, Wang Y, Li S, Yang J, Sun D. Protective function of exosomes from adipose tissue-derived mesenchymal stem cells in acute kidney injury through SIRT1 pathway. Life Sci. 2020;255:117719 pubmed publisher
Wu Z, Mulatibieke T, Niu M, Li B, Dai J, Ye X, et al. Inhibition of Matrix Metalloproteinase with BB-94 Protects against Caerulein-Induced Pancreatitis via Modulating Neutrophil and Macrophage Activation. Gastroenterol Res Pract. 2020;2020:8903610 pubmed publisher
Jin W, Xue Y, Xue Y, Han X, Song Q, Zhang J, et al. Tannic acid ameliorates arsenic trioxide-induced nephrotoxicity, contribution of NF-κB and Nrf2 pathways. Biomed Pharmacother. 2020;126:110047 pubmed publisher
Liu S, Yang Y, Gao H, Zhou N, Wang P, Zhang Y, et al. Trehalose attenuates renal ischemia-reperfusion injury by enhancing autophagy and inhibiting oxidative stress and inflammation. Am J Physiol Renal Physiol. 2020;318:F994-F1005 pubmed publisher
Han X, Ni J, Wu Z, Wu J, Li B, Ye X, et al. Myeloid-specific dopamine D2 receptor signalling controls inflammation in acute pancreatitis via inhibiting M1 macrophage. Br J Pharmacol. 2020;177:2991-3008 pubmed publisher
Ni R, Song G, Fu X, Song R, Li L, Pu W, et al. Reactive oxygen species-responsive dexamethasone-loaded nanoparticles for targeted treatment of rheumatoid arthritis via suppressing the iRhom2/TNF-α/BAFF signaling pathway. Biomaterials. 2020;232:119730 pubmed publisher
de Vicente L, Pinto A, Muñoz V, Rovina R, da Rocha A, Gaspar R, et al. Tlr4 participates in the responses of markers of apoptosis, inflammation, and ER stress to different acute exercise intensities in mice hearts. Life Sci. 2020;240:117107 pubmed publisher
Jin W, Zhang Y, Xue Y, Han X, Zhang X, Ma Z, et al. Crocin attenuates isoprenaline-induced myocardial fibrosis by targeting TLR4/NF-κB signaling: connecting oxidative stress, inflammation, and apoptosis. Naunyn Schmiedebergs Arch Pharmacol. 2020;393:13-23 pubmed publisher
Huang M, Guo M, Wang K, Wu K, Li Y, Tian T, et al. HMGB1 Mediates Paraquat-Induced Neuroinflammatory Responses via Activating RAGE Signaling Pathway. Neurotox Res. 2019;: pubmed publisher
Li J, Liu L, Zhao Q, Chen M. Role of Interleukin-17 in Pathogenesis of Intestinal Fibrosis in Mice. Dig Dis Sci. 2019;: pubmed publisher
Lu L, Wu C, Lu B, Xie D, Wang Z, Bahaji Azami N, et al. BabaoDan cures hepatic encephalopathy by decreasing ammonia levels and alleviating inflammation in rats. J Ethnopharmacol. 2019;:112301 pubmed publisher
Zhou J, Zheng J, Zhang Y, Zheng P, Tang T, Luo J, et al. Chitosan Hydrogel Delivery System Containing Herbal Compound Functions as a Potential Antineuroinflammatory Agent. ACS Omega. 2019;4:10185-10191 pubmed publisher
Xia H, Zhu X, Zhang X, Jiang H, Li B, Wang Z, et al. Alpha-naphthoflavone attenuates non-alcoholic fatty liver disease in oleic acid-treated HepG2 hepatocytes and in high fat diet-fed mice. Biomed Pharmacother. 2019;118:109287 pubmed publisher
Wei X, Sun G, Zhao X, Wu Q, Chen L, Xu Y, et al. Human amnion mesenchymal stem cells attenuate atherosclerosis by modulating macrophage function to reduce immune response. Int J Mol Med. 2019;: pubmed publisher
Jia J, Gong X, Zhao Y, Yang Z, Ji K, Luan T, et al. Autophagy Enhancing Contributes to the Organ Protective Effect of Alpha-Lipoic Acid in Septic Rats. Front Immunol. 2019;10:1491 pubmed publisher
Deng J, Xu T, Yang J, Zhang K, Li Q, Yu X, et al. Sema7A, a brain immune regulator, regulates seizure activity in PTZ-kindled epileptic rats. CNS Neurosci Ther. 2019;: pubmed publisher
Zhang G, Zheng H, Pyykko I, Zou J. The TLR-4/NF-κB signaling pathway activation in cochlear inflammation of rats with noise-induced hearing loss. Hear Res. 2019;379:59-68 pubmed publisher
Zhang J, Zhang Z, Zhou Q, Yang Y, Wang Y. Highly-acylated anthocyanins from purple sweet potato (Ipomoea batatas L.) alleviate hyperuricemia and kidney inflammation in hyperuricemic mice: possible attenuation effects on allopurinol. J Agric Food Chem. 2019;: pubmed publisher
Xu F, Hou B, Zhu X, Liu Y, Shi X, Li S, et al. Vaccaria n-Butanol Extract Lower the Production of Proinflammatory Cytokines and the Infection Risk of T. spiralis In Vivo. Acta Parasitol. 2019;: pubmed publisher
Chen X, Fu E, Lou H, Mao X, Yan B, Tong F, et al. IL-6 induced M1 type macrophage polarization increases radiosensitivity in HPV positive head and neck cancer. Cancer Lett. 2019;456:69-79 pubmed publisher
Guo H, Feng C, Zhang W, Luo Z, Zhang H, Zhang T, et al. Liver-target nanotechnology facilitates berberine to ameliorate cardio-metabolic diseases. Nat Commun. 2019;10:1981 pubmed publisher
Zheng J, Fan R, Wu H, Yao H, Yan Y, Liu J, et al. Directed self-assembly of herbal small molecules into sustained release hydrogels for treating neural inflammation. Nat Commun. 2019;10:1604 pubmed publisher
Tan B, Luo W, Shen Z, Xiao M, Wu S, Meng X, et al. Roseburia intestinalis inhibits oncostatin M and maintains tight junction integrity in a murine model of acute experimental colitis. Scand J Gastroenterol. 2019;54:432-440 pubmed publisher
Zhang S, He K, Zhou W, Cao J, Jin Z. miR‑494‑3p regulates lipopolysaccharide‑induced inflammatory responses in RAW264.7 cells by targeting PTEN. Mol Med Rep. 2019;19:4288-4296 pubmed publisher
Yang C, Lu M, Chen W, He Z, Hou X, Feng M, et al. Thyrotropin aggravates atherosclerosis by promoting macrophage inflammation in plaques. J Exp Med. 2019;216:1182-1198 pubmed publisher
He M, Huang X, Gao G, Zhou T, Li W, Hu J, et al. Olanzapine-induced endoplasmic reticulum stress and inflammation in the hypothalamus were inhibited by an ER stress inhibitor 4-phenylbutyrate. Psychoneuroendocrinology. 2019;104:286-299 pubmed publisher
Deng J, Xia Y, Zhou Q, Wang X, Xiong C, Shao X, et al. Protective effect of rosiglitazone on chronic renal allograft dysfunction in rats. Transpl Immunol. 2019;54:20-28 pubmed publisher
Chen S, Zeng X, Zong W, Wang X, Chen L, Zhou L, et al. Aucubin Alleviates Seizures Activity in Li-Pilocarpine-Induced Epileptic Mice: Involvement of Inhibition of Neuroinflammation and Regulation of Neurotransmission. Neurochem Res. 2019;44:472-484 pubmed publisher
Zheng C, Wu S, Lian H, Lin Y, Zhuang R, Thapa S, et al. Low-intensity pulsed ultrasound attenuates cardiac inflammation of CVB3-induced viral myocarditis via regulation of caveolin-1 and MAPK pathways. J Cell Mol Med. 2019;23:1963-1975 pubmed publisher
Li M, Xu J, Mei X, Chi G, Li L, Song Y, et al. Regulatory effects of dermal papillary pluripotent stem cells on polarization of macrophages from M1 to M2 phenotype in vitro. Transpl Immunol. 2019;52:57-67 pubmed publisher
Ruan L, Li M, Xing Y, Hong W, Chen C, Chen J, et al. Hepatotoxicity and hepatoprotection of Polygonum multiflorum Thund. as two sides of the same biological coin. J Ethnopharmacol. 2019;230:81-94 pubmed publisher
Deng J, Feng J, Liu T, Lu X, Wang W, Liu N, et al. Beraprost sodium preconditioning prevents inflammation, apoptosis, and autophagy during hepatic ischemia-reperfusion injury in mice via the P38 and JNK pathways. Drug Des Devel Ther. 2018;12:4067-4082 pubmed publisher
Luo D, Liu L, Liang F, Yu Z, Chen R. Electroacupuncture: A Feasible Sirt1 Promoter Which Modulates Metainflammation in Diet-Induced Obesity Rats. Evid Based Complement Alternat Med. 2018;2018:5302049 pubmed publisher
Wang B, Zhang G, Yang M, Liu N, Li Y, Ma H, et al. Neuroprotective Effect of Anethole Against Neuropathic Pain Induced by Chronic Constriction Injury of the Sciatic Nerve in Mice. Neurochem Res. 2018;43:2404-2422 pubmed publisher
Huang D, Chen J, Yang L, Ouyang Q, Li J, Lao L, et al. NKILA lncRNA promotes tumor immune evasion by sensitizing T cells to activation-induced cell death. Nat Immunol. 2018;19:1112-1125 pubmed publisher
Wang J, Xie W, Liu F, Bi Y, Zhu X, Wang Q, et al. NADH protect against radiation enteritis by enhancing autophagy and inhibiting inflammation through PI3K/AKT pathway. Am J Transl Res. 2018;10:1713-1721 pubmed
Yang C, Chang C, Chang M, Shyur L. Plant galactolipid dLGG suppresses lung metastasis of melanoma through deregulating TNF-α-mediated pulmonary vascular permeability and circulating oxylipin dynamics in mice. Int J Cancer. 2018;143:3248-3261 pubmed publisher
Wang Y, Guan M, Zhao X, Li X. Effects of garlic polysaccharide on alcoholic liver fibrosis and intestinal microflora in mice. Pharm Biol. 2018;56:325-332 pubmed publisher
Liu J, Zhao H, Wang Y, Shao Y, Li J, Xing M. Alterations of antioxidant indexes and inflammatory cytokine expression aggravated hepatocellular apoptosis through mitochondrial and death receptor-dependent pathways in Gallus gallus exposed to arsenic and copper. Environ Sci Pollut Res Int. 2018;25:15462-15473 pubmed publisher
Xie M, Fu Z, Cao J, Liu Y, Wu J, Li Q, et al. MicroRNA-132 and microRNA-212 mediate doxorubicin resistance by down-regulating the PTEN-AKT/NF-κB signaling pathway in breast cancer. Biomed Pharmacother. 2018;102:286-294 pubmed publisher
Ju S, Lee S, Chakkarapani S, Kim K, Yu H, Kang S. One-Shot Dual-Code Immunotargeting for Ultra-Sensitive Tumor Necrosis Factor-α Nanosensors by 3D Enhanced Dark-Field Super-Resolution Microscopy. Anal Chem. 2018;90:5100-5107 pubmed publisher
Ji X, Wang H, Wu Z, Zhong X, Zhu M, Zhang Y, et al. Specific Inhibitor of Smad3 (SIS3) Attenuates Fibrosis, Apoptosis, and Inflammation in Unilateral Ureteral Obstruction Kidneys by Inhibition of Transforming Growth Factor β (TGF-β)/Smad3 Signaling. Med Sci Monit. 2018;24:1633-1641 pubmed
Yang Y, Liu X, Liu Y, Fu H, Gao Y, Liu X, et al. The development of salt-sensitive hypertension regulated by PSGL-1 gene in mice. Cell Biosci. 2018;8:20 pubmed publisher
Chen H, Xu Z, Li X, Yang Y, Li B, Li Y, et al. α-catenin SUMOylation increases IκBα stability and inhibits breast cancer progression. Oncogenesis. 2018;7:28 pubmed publisher
Zhang J, Tucker L, DongYan -, Lu Y, Yang L, Wu C, et al. Tert-butylhydroquinone post-treatment attenuates neonatal hypoxic-ischemic brain damage in rats. Neurochem Int. 2018;116:1-12 pubmed publisher
Chen S, Li R, Cheng C, Xu J, Jin C, Gao F, et al. Pseudomonas aeruginosa infection alters the macrophage phenotype switching process during wound healing in diabetic mice. Cell Biol Int. 2018;42:877-889 pubmed publisher
Wang W, Wen D, Duan W, Yin J, Cui C, Wang Y, et al. Systemic administration of scAAV9-IGF1 extends survival in SOD1G93A ALS mice via inhibiting p38 MAPK and the JNK-mediated apoptosis pathway. Brain Res Bull. 2018;139:203-210 pubmed publisher
Shen Z, Ma Y, Ji Z, Hao Y, Yan X, Zhong Y, et al. Arachidonic acid induces macrophage cell cycle arrest through the JNK signaling pathway. Lipids Health Dis. 2018;17:26 pubmed publisher
Xue J, Li R, Zhao X, Ma C, Lv X, Liu L, et al. Morusin induces paraptosis-like cell death through mitochondrial calcium overload and dysfunction in epithelial ovarian cancer. Chem Biol Interact. 2018;283:59-74 pubmed publisher
Jia Y, Lu H, Peng Y, Zhang B, Gong X, Su J, et al. Oxyresveratrol prevents lipopolysaccharide/d-galactosamine-induced acute liver injury in mice. Int Immunopharmacol. 2018;56:105-112 pubmed publisher
Yan L, Liu Y, Sun C, Zheng Q, Hao P, Zhai J, et al. Effects of Ovariectomy in an hSOD1-G93A Transgenic Mouse Model of Amyotrophic Lateral Sclerosis (ALS). Med Sci Monit. 2018;24:678-686 pubmed
Wang F, Guo T, Jiang H, Li R, Wang T, Zeng N, et al. A comparison of CRISPR/Cas9 and siRNA-mediated ALDH2 gene silencing in human cell lines. Mol Genet Genomics. 2018;293:769-783 pubmed publisher
Wang X, Li D, Fan L, Xiao Q, Zuo H, Li Z. CAPE-pNO2 ameliorated diabetic nephropathy through regulating the Akt/NF-?B/ iNOS pathway in STZ-induced diabetic mice. Oncotarget. 2017;8:114506-114525 pubmed publisher
Hu C, Lu Y, Chen X, Wu Z, Zhang Q. Gene transfer of a naked plasmid (pUDK-HGF) encoding human hepatocyte growth factor attenuates skin/muscle incision and retraction-induced chronic post-surgical pain in rats. Eur J Pain. 2018;22:961-972 pubmed publisher
Sun H, Chen D, Wang P, Wan M, Zhang C, Zhang Z, et al. Salusin-? Is Involved in Diabetes Mellitus-Induced Endothelial Dysfunction via Degradation of Peroxisome Proliferator-Activated Receptor Gamma. Oxid Med Cell Longev. 2017;2017:6905217 pubmed publisher
Ji Y, Duan W, Liu Y, Liu Y, Liu C, Li Y, et al. IGF1 affects macrophage invasion and activation and TNF-α production in the sciatic nerves of female SOD1G93A mice. Neurosci Lett. 2018;668:1-6 pubmed publisher
Yan X, Lei F, Hu Y, Nie L, Jia Q, Zhou H, et al. Hydrogen sulfide protects neonatal rat medulla oblongata against prenatal cigarette smoke exposure via anti-oxidative and anti-inflammatory effects. Environ Toxicol Pharmacol. 2018;57:151-158 pubmed publisher
Wang Y, Zhao H, Shao Y, Liu J, Li J, Xing M. Copper or/and arsenic induce oxidative stress-cascaded, nuclear factor kappa B-dependent inflammation and immune imbalance, trigging heat shock response in the kidney of chicken. Oncotarget. 2017;8:98103-98116 pubmed publisher
Chen S, Zheng P, Wang W, Yi M, Chen P, Cai J, et al. Abberent expression of NOR1 protein in tumor associated macrophages contributes to the development of DEN-induced hepatocellular carcinoma. J Cell Physiol. 2018;233:5002-5013 pubmed publisher
Li D, Wang X, Huang Q, Li S, Zhou Y, Li Z. Cardioprotection of CAPE-oNO2 against myocardial ischemia/reperfusion induced ROS generation via regulating the SIRT1/eNOS/NF-?B pathway in vivo and in vitro. Redox Biol. 2018;15:62-73 pubmed publisher
Chen J, Li D. Telbivudine attenuates UUO-induced renal fibrosis via TGF-?/Smad and NF-?B signaling. Int Immunopharmacol. 2018;55:1-8 pubmed publisher
Zeng H, Yu F, Zhang Z, Yang Q, Jin S, He X, et al. Quantitative proteomics study of host response to virulent and attenuated pseudorabies virus infection in mouse brain. Biochim Biophys Acta Proteins Proteom. 2018;1866:307-315 pubmed publisher
Xu S, Niu P, Chen K, Xia Y, Yu Q, Liu N, et al. The liver protection of propylene glycol alginate sodium sulfate preconditioning against ischemia reperfusion injury: focusing MAPK pathway activity. Sci Rep. 2017;7:15175 pubmed publisher
Yang L, Tucker D, Dong Y, Wu C, Lu Y, Li Y, et al. Photobiomodulation therapy promotes neurogenesis by improving post-stroke local microenvironment and stimulating neuroprogenitor cells. Exp Neurol. 2018;299:86-96 pubmed publisher
Sun X, Li J, Zhao H, Wang Y, Liu J, Shao Y, et al. Synergistic effect of copper and arsenic upon oxidative stress, inflammation and autophagy alterations in brain tissues of Gallus gallus. J Inorg Biochem. 2018;178:54-62 pubmed publisher
Zheng X, Ma W, Sun R, Yin H, Lin F, Liu Y, et al. Butaselen prevents hepatocarcinogenesis and progression through inhibiting thioredoxin reductase activity. Redox Biol. 2018;14:237-249 pubmed publisher
Han X, Li B, Ye X, Mulatibieke T, Wu J, Dai J, et al. Dopamine D2 receptor signalling controls inflammation in acute pancreatitis via a PP2A-dependent Akt/NF-?B signalling pathway. Br J Pharmacol. 2017;: pubmed publisher
Li S, Zhao H, Wang Y, Shao Y, Li J, Liu J, et al. The inflammatory responses in Cu-mediated elemental imbalance is associated with mitochondrial fission and intrinsic apoptosis in Gallus gallus heart. Chemosphere. 2017;189:489-497 pubmed publisher
Zhang X, Zheng W, Wang T, Ren P, Wang F, Ma X, et al. Danshen-Chuanxiong-Honghua Ameliorates Cerebral Impairment and Improves Spatial Cognitive Deficits after Transient Focal Ischemia and Identification of Active Compounds. Front Pharmacol. 2017;8:452 pubmed publisher
Liu Y, Gao X, Chen L, You X. Rapamycin suppresses A?25-35- or LPS-induced neuronal inflammation via modulation of NF-?B signaling. Neuroscience. 2017;355:188-199 pubmed publisher
Gong X, Yang Y, Huang L, Zhang Q, Wan R, Zhang P, et al. Antioxidation, anti-inflammation and anti-apoptosis by paeonol in LPS/d-GalN-induced acute liver failure in mice. Int Immunopharmacol. 2017;46:124-132 pubmed publisher
Fu J, Xia X, Liu Z, Wang Y, Wang Y, Shi Q, et al. The acute exposure of tetrachloro-p-benzoquinone (a.k.a. chloranil) triggers inflammation and neurological dysfunction via Toll-like receptor 4 signaling: The protective role of melatonin preconditioning. Toxicology. 2017;381:39-50 pubmed publisher
Jiang W, Guo M, Hai X. Hepatoprotective and antioxidant effects of lycopene on non-alcoholic fatty liver disease in rat. World J Gastroenterol. 2016;22:10180-10188 pubmed publisher
Wang W, Duan W, Wang Y, Wen D, Liu Y, Li Z, et al. Intrathecal Delivery of ssAAV9-DAO Extends Survival in SOD1G93A ALS Mice. Neurochem Res. 2017;42:986-996 pubmed publisher
Liu X, Grogan T, Hieronymus H, Hashimoto T, Mottahedeh J, Cheng D, et al. Low CD38 Identifies Progenitor-like Inflammation-Associated Luminal Cells that Can Initiate Human Prostate Cancer and Predict Poor Outcome. Cell Rep. 2016;17:2596-2606 pubmed publisher
Wu Y, Liu W, Xue B, Zhang L, Liu X, Liu B, et al. Upregulated Expression of microRNA-16 Correlates with Th17/Treg Cell Imbalance in Patients with Rheumatoid Arthritis. DNA Cell Biol. 2016;35:853-860 pubmed
Zhang Z, Zhang D, Dou M, Li Z, Zhang J, Zhao X. Dendrobium officinale Kimura et Migo attenuates diabetic cardiomyopathy through inhibiting oxidative stress, inflammation and fibrosis in streptozotocin-induced mice. Biomed Pharmacother. 2016;84:1350-1358 pubmed publisher
Fu J, Shi Q, Song X, Xia X, Su C, Liu Z, et al. Tetrachlorobenzoquinone exhibits neurotoxicity by inducing inflammatory responses through ROS-mediated IKK/IκB/NF-κB signaling. Environ Toxicol Pharmacol. 2016;41:241-50 pubmed publisher
Shi Q, Song X, Fu J, Su C, Xia X, Song E, et al. Artificial sweetener neohesperidin dihydrochalcone showed antioxidative, anti-inflammatory and anti-apoptosis effects against paraquat-induced liver injury in mice. Int Immunopharmacol. 2015;29:722-729 pubmed publisher
Zhai Y, Wu B, Li J, Yao X, Zhu P, Chen Z. CD147 promotes IKK/IκB/NF-κB pathway to resist TNF-induced apoptosis in rheumatoid arthritis synovial fibroblasts. J Mol Med (Berl). 2016;94:71-82 pubmed publisher
Wang D, Chen S, Liu M, Liu C. Maternal obesity disrupts circadian rhythms of clock and metabolic genes in the offspring heart and liver. Chronobiol Int. 2015;32:615-26 pubmed publisher
Xu D, Hu L, Su C, Xia X, Zhang P, Fu J, et al. Tetrachloro-p-benzoquinone induces hepatic oxidative damage and inflammatory response, but not apoptosis in mouse: the prevention of curcumin. Toxicol Appl Pharmacol. 2014;280:305-13 pubmed publisher
Xia X, Su C, Fu J, Zhang P, Jiang X, Xu D, et al. Role of ?-lipoic acid in LPS/d-GalN induced fulminant hepatic failure in mice: studies on oxidative stress, inflammation and apoptosis. Int Immunopharmacol. 2014;22:293-302 pubmed publisher
Wu Y, Huang A, Li T, Su X, Ding H, Li H, et al. MiR-152 reduces human umbilical vein endothelial cell proliferation and migration by targeting ADAM17. FEBS Lett. 2014;588:2063-9 pubmed publisher
product information
CatalogNo :
60291-1-Ig
AntigenName :
TNF alpha
Package :
150UL
Price :
299 USD
Exsists20ul :
20ul trial size available
FullName :
tumor necrosis factor (TNF superfamily, member 2)
Immunogen :
Recombinant Protein
Species :
chicken, human, mouse, rat
Host :
Mouse
IsConjugated :
Unconjugated
AntigenSpecies :
human
CloneNo :
7B8A11
Application :
WB, IHC, IF, FC, ELISA
Clonlity :
Monoclonal
IsoType :
IgG2b
Synonyms :
Cachectin, DIF, TNF, TNF a, TNF alpha, TNFA, TNF-a, TNFSF2, TNFα, Tumor necrosis factor
PrimaryOrSecondary :
Primary
AntibodyBuffer :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
GenBankNo :
BC028148
Category :
Apoptosis;Binding Proteins;Cell Cycle;Cytoskeleton/Scaffold Proteins;Growth Factor/Cytokine/Hormone;Immunology;Membrane Proteins;Neurology;Signal transduction;
PurifyMethod :
Protein A purification
NewAb :
False
IsSellable :
True
Feature :
siRNA
AppTiter :
IF 1:100 ; IHC 1:800 ; WB 1:2000 ;
company information
Proteintech Group
2201 W. Campbell Park Dr. STE12
Chicago, IL 60612
Proteintech@ptglab.com
https://www.ptglab.com
1-312-455-8498
headquarters: USA
At Proteintech, we produce every single antibody we sell; we do not rely on or supply to any other antibody providers: our products are unique and we are 100% accountable for each one. We realize this accountability by validating in-house, providing extensive technical support and guaranteeing your success: in addition to helping you troubleshoot your experiment, we will offer you a full cash refund if you are in any way dissatisfied. We can guarantee satisfaction because we have confidence in our products, confidence cultivated by the science behind our antibodies: we make them using as much of the native protein as possible, and purifying them using affinity purification with the original antigen. We carry out antibody production over a 102-day period, which allows for better antigen fitting to MHC molecules and affinity maturation in the host. This approach results in higher affinity antibodies with greater sensitivity, which you can use in any application and in multiple species.
You can only buy Proteintech antibodies directly from Proteintech or via one of its approved distributors — when you receive your antibody and see the Proteintech logo on the vial, know that you hold something that is truly unique.