This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Proteintech Group
product type :
antibody
product name :
4EBP1
catalog :
60246-1-Ig
quantity :
150UL
price :
299 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
2C3F3
reactivity :
human
application :
western blot, ELISA, immunocytochemistry
citations: 13
Published Application/Species/Sample/DilutionReference
  • western blot; human; 1:1000; loading ...; fig 2e
Zhou C, Qian X, Hu M, Zhang R, Liu N, Huang Y, et al. STYK1 promotes autophagy through enhancing the assembly of autophagy-specific class III phosphatidylinositol 3-kinase complex I. Autophagy. 2019;:1-21 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 2f, 4g
Zhou C, Wang M, Yang J, Xiong H, Wang Y, Tang J. Integral membrane protein 2A inhibits cell growth in human breast cancer via enhancing autophagy induction. Cell Commun Signal. 2019;17:105 pubmed publisher
Shi Y, Li F, Wang S, Wang C, Xie Y, Zhou J, et al. miR-196b-5p controls adipocyte differentiation and lipogenesis through regulating mTORC1 and TGF-β signaling. FASEB J. 2020;: pubmed publisher
Dai W, Xu L, Yu X, Zhang G, Guo H, Liu H, et al. OGDHL silencing promotes hepatocellular carcinoma by reprogramming glutamine metabolism. J Hepatol. 2020;72:909-923 pubmed publisher
Zheng R, Huang S, Zhu J, Lin W, Xu H, Zheng X. Leucine attenuates muscle atrophy and autophagosome formation by activating PI3K/AKT/mTOR signaling pathway in rotator cuff tears. Cell Tissue Res. 2019;: pubmed publisher
Huang T, Liu D, Wang Y, Li P, Sun L, Xiong H, et al. FGFR2 Promotes Gastric Cancer Progression by Inhibiting the Expression of Thrombospondin4 via PI3K-Akt-Mtor Pathway. Cell Physiol Biochem. 2018;50:1332-1345 pubmed publisher
Wang H, Wu J, Gai J, Yang S, Ma Q, Ma H, et al. MAN1B1 is associated with poor prognosis and modulates proliferation and apoptosis in bladder cancer. Gene. 2018;679:314-319 pubmed publisher
Usman M, Gao J, Zheng T, Rui C, Li T, Bian X, et al. Macrophages confer resistance to PI3K inhibitor GDC-0941 in breast cancer through the activation of NF-κB signaling. Cell Death Dis. 2018;9:809 pubmed publisher
Jin J, Hu K, Ye M, Wu D, He Q. Rapamycin Reduces Podocyte Apoptosis and is Involved in Autophagy and mTOR/ P70S6K/4EBP1 Signaling. Cell Physiol Biochem. 2018;48:765-772 pubmed publisher
Yang Y, Qi Q, Wang Y, Shi Y, Yang W, Cen Y, et al. Cysteine-rich protein 61 regulates adipocyte differentiation from mesenchymal stem cells through mammalian target of rapamycin complex 1 and canonical Wnt signaling. FASEB J. 2018;32:3096-3107 pubmed publisher
Huang R, Liu H, Chen Y, He Y, Kang Q, Tu S, et al. EPS8 regulates proliferation, apoptosis and chemosensitivity in BCR-ABL positive cells via the BCR-ABL/PI3K/AKT/mTOR pathway. Oncol Rep. 2018;39:119-128 pubmed publisher
Liu X, Duan C, Ji J, Zhang T, Yuan X, Zhang Y, et al. Cucurbitacin B induces autophagy and apoptosis by suppressing CIP2A/PP2A/mTORC1 signaling axis in human cisplatin resistant gastric cancer cells. Oncol Rep. 2017;38:271-278 pubmed publisher
Wang D, Wang M, Jiang N, Zhang Y, Bian X, Wang X, et al. Effective use of PI3K inhibitor BKM120 and PARP inhibitor Olaparib to treat PIK3CA mutant ovarian cancer. Oncotarget. 2016;7:13153-66 pubmed publisher
product information
CatalogNo :
60246-1-Ig
AntigenName :
4EBP1
Package :
150UL
Price :
299 USD
Exsists20ul :
20ul trial size available
FullName :
eukaryotic translation initiation factor 4E binding protein 1
Immunogen :
Fusion Protein
Species :
human, mouse, rat
Host :
Mouse
IsConjugated :
Unconjugated
AntigenSpecies :
human
CloneNo :
2C3F3
Application :
WB, IF, ELISA
Clonlity :
Monoclonal
IsoType :
IgG2b
Synonyms :
4E BP1, 4EBP1, BP 1, eIF4E binding protein 1, EIF4EBP1, PHAS I
PrimaryOrSecondary :
Primary
AntibodyBuffer :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
GenBankNo :
BC004459
Category :
Binding Proteins;Cell Cycle;Cytoskeleton/Scaffold Proteins;Metabolism;Oncogene(s) and Tumor Suppressor(s);
PurifyMethod :
Protein A purification
NewAb :
False
IsSellable :
True
Feature :
siRNA
AppTiter :
IF 1:100 ; WB 1:2000 ;
company information
Proteintech Group
2201 W. Campbell Park Dr. STE12
Chicago, IL 60612
Proteintech@ptglab.com
https://www.ptglab.com
1-312-455-8498
headquarters: USA
At Proteintech, we produce every single antibody we sell; we do not rely on or supply to any other antibody providers: our products are unique and we are 100% accountable for each one. We realize this accountability by validating in-house, providing extensive technical support and guaranteeing your success: in addition to helping you troubleshoot your experiment, we will offer you a full cash refund if you are in any way dissatisfied. We can guarantee satisfaction because we have confidence in our products, confidence cultivated by the science behind our antibodies: we make them using as much of the native protein as possible, and purifying them using affinity purification with the original antigen. We carry out antibody production over a 102-day period, which allows for better antigen fitting to MHC molecules and affinity maturation in the host. This approach results in higher affinity antibodies with greater sensitivity, which you can use in any application and in multiple species.
You can only buy Proteintech antibodies directly from Proteintech or via one of its approved distributors — when you receive your antibody and see the Proteintech logo on the vial, know that you hold something that is truly unique.