AKT | Proteintech Group 60203-2-Ig product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Proteintech Group

product type :

antibody

product name :

AKT

catalog :

60203-2-Ig

quantity :

150UL

price :

299 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

2C5D1

reactivity :

hamsters, human, mouse, rat

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation

citations: 38

Published Application/Species/Sample/Dilution	Reference
western blot; human; 1:5000; loading ...; fig 4a	Luo C, Wang Y, Wei C, Chen Y, Ji Z. The anti-migration and anti-invasion effects of Bruceine D in human triple-negative breast cancer MDA-MB-231 cells. Exp Ther Med. 2020;19:273-279 pubmed publisher
western blot; human; 1:1000; loading ...; fig 3d	Wang Q, Jia S, Jiao Y, Xu L, Wang D, Chen X, et al. SSRP1 influences colorectal cancer cell growth and apoptosis via the AKT pathway. Int J Med Sci. 2019;16:1573-1582 pubmed publisher
western blot; rat; loading ...; fig 5f western blot; human; loading ...; fig 5a	Tian S, Jia W, Lu M, Zhao J, Sun X. Dual-specificity tyrosine phosphorylation-regulated kinase 1A ameliorates insulin resistance in neurons by up-regulating IRS-1 expression. J Biol Chem. 2019;: pubmed publisher
western blot; mouse; loading ...; fig 6b western blot; human; loading ...; fig 7a	Zhang Y, Cao Y, Chen J, Qin H, Yang L. A New Possible Mechanism by Which Punicalagin Protects against Liver Injury Induced by Type 2 Diabetes Mellitus: Upregulation of Autophagy via the Akt/FoxO3a Signaling Pathway. J Agric Food Chem. 2019;: pubmed publisher
western blot; human; 1:5000; loading ...; fig 6c	Li F, Wu J, Wang P, Qu L. NKAP functions as an oncogene in Ewing sarcoma cells partly through the AKT signaling pathway. Exp Ther Med. 2019;18:3037-3045 pubmed publisher
western blot; human; 1:5000; loading ...; fig 6b	Ma Y, Guan L, Han Y, Zhou Y, Li X, Liu Y, et al. siPRDX2-elevated DNM3 inhibits the proliferation and metastasis of colon cancer cells via AKT signaling pathway. Cancer Manag Res. 2019;11:5799-5811 pubmed publisher
western blot; hamsters; 1:1000; loading ...; fig 6c western blot; human; 1:1000; loading ...; fig 6c	Wu Y, Tan X, Liu P, Yang Y, Huang Y, Liu X, et al. ITGA6 and RPSA synergistically promote pancreatic cancer invasion and metastasis via PI3K and MAPK signaling pathways. Exp Cell Res. 2019;379:30-47 pubmed publisher
western blot; human; 1:500; loading ...; fig 5d	Guo Y, Pei X. Tetrandrine-Induced Autophagy in MDA-MB-231 Triple-Negative Breast Cancer Cell through the Inhibition of PI3K/AKT/mTOR Signaling. Evid Based Complement Alternat Med. 2019;2019:7517431 pubmed publisher
western blot; mouse; fig s1	Yang Z, Huang C, Wu Y, Chen B, Zhang W, Zhang J. Autophagy Protects the Blood-Brain Barrier Through Regulating the Dynamic of Claudin-5 in Short-Term Starvation. Front Physiol. 2019;10:2 pubmed publisher
	Li Z, Zhou Z, Wu X, Zhou Q, Liao C, Liu Y, et al. LMP1 promotes nasopharyngeal carcinoma metastasis through NTRK2-mediated anoikis resistance. Am J Cancer Res. 2020;10:2083-2099 pubmed
	Li X, Qiu W, Li N, Da X, Ma Q, Hou Y, et al. Susceptibility to Hyperglycemia in Rats With Stress-Induced Depressive-Like Behavior: Involvement of IL-6 Mediated Glucose Homeostasis Signaling. Front Psychiatry. 2020;11:557 pubmed publisher
	Dai H, Li M, Yang W, Sun X, Wang P, Wang X, et al. Resveratrol inhibits the malignant progression of hepatocellular carcinoma via MARCH1-induced regulation of PTEN/AKT signaling. Aging (Albany NY). 2020;12:11717-11731 pubmed publisher
	Lin L, Luo X, Wang L, Xu F, He Y, Wang Q, et al. BML-111 inhibits EMT, migration and metastasis of TAMs-stimulated triple-negative breast cancer cells via ILK pathway. Int Immunopharmacol. 2020;85:106625 pubmed publisher
	Meng X, Zhang C, Guo Y, Han Y, Wang C, Chu H, et al. TBHQ Attenuates Neurotoxicity Induced by Methamphetamine in the VTA through the Nrf2/HO-1 and PI3K/AKT Signaling Pathways. Oxid Med Cell Longev. 2020;2020:8787156 pubmed publisher
	Li J, Ma J, Tian Y, Zhao P, Liu X, Dong H, et al. Effective-component compatibility of Bufei Yishen formula II inhibits mucus hypersecretion of chronic obstructive pulmonary disease rats by regulating EGFR/PI3K/mTOR signaling. J Ethnopharmacol. 2020;257:112796 pubmed publisher
	Xu F, Xu Y, Xiong J, Zhang J, Wu J, Luo J, et al. AOC1 Contributes to Tumor Progression by Promoting the AKT and EMT Pathways in Gastric Cancer. Cancer Manag Res. 2020;12:1789-1798 pubmed publisher
	Peng X, Yang J, Qiang Y, Sun R, Cao Y, Zheng L, et al. PTPN3 Inhibits the Growth and Metastasis of Clear Cell Renal Cell Carcinoma via Inhibition of PI3K/AKT Signaling. Mol Cancer Res. 2020;18:903-912 pubmed publisher
	Ye X, Tian W, Wang G, Zhang X, Zhou M, Zeng D, et al. Phenolic Glycosides from the Roots of Ficus hirta Vahl. and Their Antineuroinflammatory Activities. J Agric Food Chem. 2020;68:4196-4204 pubmed publisher
	Feng A, Han X, Meng X, Chen Z, Li Q, Shu W, et al. PRDX2 plays an oncogenic role in esophageal squamous cell carcinoma via Wnt/β-catenin and AKT pathways. Clin Transl Oncol. 2020;22:1838-1848 pubmed publisher
	Labuzan S, Lynch S, Cooper L, Waddell D. Inhibition of protein phosphatase methylesterase 1 dysregulates MAP kinase signaling and attenuates muscle cell differentiation. Gene. 2020;739:144515 pubmed publisher
	Cooper L, Hanson A, Kavanagh J, Waddell D. Fam83d modulates MAP kinase and AKT signaling and is induced during neurogenic skeletal muscle atrophy. Cell Signal. 2020;70:109576 pubmed publisher
	Liu Y, Zhang M, He T, Yang W, Wang L, Zhang L, et al. Epigenetic silencing of IGFBPL1 promotes esophageal cancer growth by activating PI3K-AKT signaling. Clin Epigenetics. 2020;12:22 pubmed publisher
	Yang Z, Yang L, Xu C, Wang X, Lei L. An insertion mutation of ERBB2 enhances breast cancer cell growth and confers resistance to lapatinib through AKT signaling pathway. Biol Open. 2020;9: pubmed publisher
	Zheng Y, Nie P, Xu S. Long noncoding RNA linc00467 plays an oncogenic role in hepatocellular carcinoma by regulating the miR-18a-5p/NEDD9 axis. J Cell Biochem. 2020;: pubmed publisher
	Zhang J, Chen Y, Lin J, Jia R, An T, Dong T, et al. Cyclovirobuxine D Exerts Anticancer Effects by Suppressing the EGFR-FAK-AKT/ERK1/2-Slug Signaling Pathway in Human Hepatocellular Carcinoma. DNA Cell Biol. 2020;: pubmed publisher
	Wei S, Xie S, Yang Z, Peng X, Gong L, Zhao K, et al. Allogeneic adipose-derived stem cells suppress mTORC1 pathway in a murine model of systemic lupus erythematosus. Lupus. 2019;28:199-209 pubmed publisher
	Suo L, Chang X, Zhao Y. The Orexin-A-Regulated Akt/mTOR Pathway Promotes Cell Proliferation Through Inhibiting Apoptosis in Pancreatic Cancer Cells. Front Endocrinol (Lausanne). 2018;9:647 pubmed publisher
	Jiang Y, Liu J, Zhou Z, Liu K, Liu C. Diosmetin Attenuates Akt Signaling Pathway by Modulating Nuclear Factor Kappa-Light-Chain-Enhancer of Activated B Cells (NF-κB)/Inducible Nitric Oxide Synthase (iNOS) in Streptozotocin (STZ)-Induced Diabetic Nephropathy Mice. Med Sci Monit. 2018;24:7007-7014 pubmed publisher
	Feng J, Niu P, Chen K, Wu L, Liu T, Xu S, et al. Salidroside mediates apoptosis and autophagy inhibition in concanavalin A-induced liver injury. Exp Ther Med. 2018;15:4599-4614 pubmed publisher
	Gao W, Xiao C, Hu J, Chen B, Wang C, Cui B, et al. Qing brick tea (QBT) aqueous extract protects monosodium glutamate-induced obese mice against metabolic syndrome and involves up-regulation Transcription Factor Nuclear Factor-Erythroid 2-Related Factor 2 (Nrf2) antioxidant pathway. Biomed Pharmacother. 2018;103:637-644 pubmed publisher
	Li H, Tang Z, Chu P, Song Y, Yang Y, Sun B, et al. Neuroprotective effect of phosphocreatine on oxidative stress and mitochondrial dysfunction induced apoptosis in vitro and in vivo: Involvement of dual PI3K/Akt and Nrf2/HO-1 pathways. Free Radic Biol Med. 2018;120:228-238 pubmed publisher
	Zhang H, Cao Y, Chen Y, Li G, Yu H. Apatinib promotes apoptosis of the SMMC-7721 hepatocellular carcinoma cell line via the PI3K/Akt pathway. Oncol Lett. 2018;15:5739-5743 pubmed publisher
	Li X, Wang G, Qili M, Liang H, Li T, E X, et al. Aspirin Reduces Cardiac Interstitial Fibrosis by Inhibiting Erk1/2-Serpine2 and P-Akt Signalling Pathways. Cell Physiol Biochem. 2018;45:1955-1965 pubmed publisher
	Wei X, Nie S, Liu H, Sun J, Liu J, Li J, et al. Angiopoietin-like protein 2 facilitates non-small cell lung cancer progression by promoting the polarization of M2 tumor-associated macrophages. Am J Cancer Res. 2017;7:2220-2233 pubmed
	Zhang Y, Gong F, Lu Z, Wang H, Cheng Y, Liu Z, et al. DHPAC, a novel synthetic microtubule destabilizing agent, possess high anti-tumor activity in vincristine-resistant oral epidermoid carcinoma in vitro and in vivo. Int J Biochem Cell Biol. 2017;93:1-11 pubmed publisher
	Yu J, Zhang W, Qian H, Tang H, Lin W, Lu B. SOCS1 regulates hepatic regenerative response and provides prognostic makers for acute obstructive cholangitis. Sci Rep. 2017;7:9482 pubmed publisher
	Wu L, Zhang Q, Mo W, Feng J, Li S, Li J, et al. Quercetin prevents hepatic fibrosis by inhibiting hepatic stellate cell activation and reducing autophagy via the TGF-β1/Smads and PI3K/Akt pathways. Sci Rep. 2017;7:9289 pubmed publisher
	Shen C, Wei W, Qiu Z, Song H, Zhang X, Sun Z, et al. Metformin reduces glycometabolism of papillary thyroid carcinoma in vitro and in vivo. J Mol Endocrinol. 2017;58:15-23 pubmed

product information

CatalogNo :

60203-2-Ig

AntigenName :

AKT

Package :

150UL

Price :

299 USD

Exsists20ul :

20ul trial size available

FullName :

v-akt murine thymoma viral oncogene homolog 1

Immunogen :

Fusion Protein

Species :

hamster, human, mouse, rat

Host :

Mouse

IsConjugated :

Unconjugated

AntigenSpecies :

human

CloneNo :

2C5D1

Application :

WB, IP, IHC, IF, ELISA

Clonlity :

Monoclonal

IsoType :

IgG1

Synonyms :

AKT, AKT (pan), AKT pan, AKT1, AKT1/2/3, pan AKT, PKB, PKB ALPHA, PRKBA, Protein kinase B, Proto oncogene c Akt, RAC, RAC ALPHA, RAC PK alpha, total AKT

PrimaryOrSecondary :

Primary

AntibodyBuffer :

PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

GenBankNo :

BC000479

Category :

Apoptosis;Binding Proteins;Cell Cycle;Cytoskeleton/Scaffold Proteins;Development;Membrane Proteins;Metabolism;Neurology;

PurifyMethod :

Protein A purification

NewAb :

False

IsSellable :

True

Feature :

siRNA

AppTiter :

IF 1:25 ; IHC 1:200 ; IP 1:1000 ; WB 1:5000 ;