This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Proteintech Group
product type :
antibody
product name :
GFAP
catalog :
60190-1-Ig
quantity :
150UL
price :
299 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
4B2E10
reactivity :
human, rat
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section
citations: 45
Published Application/Species/Sample/DilutionReference
  • immunocytochemistry; rat; 1:500
He G, Xu W, Li J, Li S, Liu B, Tan X, et al. Huwe1 interacts with Gadd45b under oxygen-glucose deprivation and reperfusion injury in primary Rat cortical neuronal cells. Mol Brain. 2015;8:88 pubmed publisher
  • immunohistochemistry - paraffin section; human; fig 1
Yao P, Kang D, Wang X, Lin R, Ye Z. Cell-density-dependent manifestation of partial characteristics for neuronal precursors in a newly established human gliosarcoma cell line. In Vitro Cell Dev Biol Anim. 2015;51:345-52 pubmed publisher
  • western blot; human
Zhu Z, Liu Y, Li K, Liu J, Wang H, Sun B, et al. Protein tyrosine phosphatase receptor U (PTPRU) is required for glioma growth and motility. Carcinogenesis. 2014;35:1901-10 pubmed publisher
Li W, Luo Z, Yan C, Wang X, He Z, Ouyang S, et al. Autophagic degradation of PML promotes susceptibility to HSV-1 by stress-induced corticosterone. Theranostics. 2020;10:9032-9049 pubmed publisher
Xu J, Duan Z, Qi X, Ou Y, Guo X, Zi L, et al. Injectable Gelatin Hydrogel Suppresses Inflammation and Enhances Functional Recovery in a Mouse Model of Intracerebral Hemorrhage. Front Bioeng Biotechnol. 2020;8:785 pubmed publisher
Xin D, Li T, Chu X, Ke H, Yu Z, Cao L, et al. Mesenchymal stromal cell-derived extracellular vesicles modulate microglia/macrophage polarization and protect the brain against hypoxia-ischemic injury in neonatal mice by targeting delivery of miR-21a-5p. Acta Biomater. 2020;113:597-613 pubmed publisher
Zhou C, Chen H, Zheng J, Guo Z, Huang Z, Wu Y, et al. Pentraxin 3 contributes to neurogenesis after traumatic brain injury in mice. Neural Regen Res. 2020;15:2318-2326 pubmed publisher
Guo X, Wang X, Dong J, Lv W, Zhao S, Jin L, et al. Effects of Ginkgo biloba on Early Decompression after Spinal Cord Injury. Evid Based Complement Alternat Med. 2020;2020:6958246 pubmed publisher
Ren P, Chen J, Li B, Zhang M, Yang B, Guo X, et al. Nrf2 Ablation Promotes Alzheimer's Disease-Like Pathology in APP/PS1 Transgenic Mice: The Role of Neuroinflammation and Oxidative Stress. Oxid Med Cell Longev. 2020;2020:3050971 pubmed publisher
Hossain M, Marcus J, Lee J, Garcia P, Singh V, Shacka J, et al. Restoration of CTSD (cathepsin D) and lysosomal function in stroke is neuroprotective. Autophagy. 2020;:1-19 pubmed publisher
Liu K, Yu X, Sun T, Wang Y, Chen M, Su Y, et al. Effects of seawater immersion on open traumatic brain injury in rabbit model. Brain Res. 2020;1743:146903 pubmed publisher
Yang J, Jiang Q, Yu X, Xu T, Wang Y, Deng J, et al. STK24 modulates excitatory synaptic transmission in epileptic hippocampal neurons. CNS Neurosci Ther. 2020;26:851-861 pubmed publisher
Li P, Li Y, Dai Y, Wang B, Li L, Jiang B, et al. The LncRNA H19/miR-1-3p/CCL2 axis modulates lipopolysaccharide (LPS) stimulation-induced normal human astrocyte proliferation and activation. Cytokine. 2020;131:155106 pubmed publisher
Bi W, Shao S, Li Z, Ruan Y, Luan S, Dong Z, et al. FSHR ablation induces depression-like behaviors. Acta Pharmacol Sin. 2020;41:1033-1040 pubmed publisher
Yuan C, Dai C, Li Z, Zheng L, Zhao M, Dong S. Bexarotene Improve Depression-Like Behaviour in Mice by Protecting Against Neuro-inflammation and Synaptic Damage. Neurochem Res. 2020;45:1500-1509 pubmed publisher
Luo D, Luo L, Lin R, Lin L, Lin Q. Brain-derived neurotrophic factor and Glial cell line-derived neurotrophic factor expressions in the trigeminal root entry zone and trigeminal ganglion neurons of a trigeminal neuralgia rat model. Anat Rec (Hoboken). 2020;: pubmed publisher
Song Q, Feng Y, Wang L, Shen J, Li Y, Fan C, et al. COX-2 inhibition rescues depression-like behaviors via suppressing glial activation, oxidative stress and neuronal apoptosis in rats. Neuropharmacology. 2019;160:107779 pubmed publisher
Yang Q, Huang Z, Luo Y, Zheng F, Hu Y, Liu H, et al. Inhibition of Nwd1 activity attenuates neuronal hyperexcitability and GluN2B phosphorylation in the hippocampus. EBioMedicine. 2019;47:470-483 pubmed publisher
He G, Xu W, Liao H, Jiang C, Li C, Zhang W. Silencing Huwe1 reduces apoptosis of cortical neurons exposed to oxygen-glucose deprivation and reperfusion. Neural Regen Res. 2019;14:1977-1985 pubmed publisher
Luo D, Lin R, Luo L, Li Q, Chen T, Qiu R, et al. Glial Plasticity in the Trigeminal Root Entry Zone of a Rat Trigeminal Neuralgia Animal Model. Neurochem Res. 2019;: pubmed publisher
Zhou X, Chu X, Yuan H, Qiu J, Zhao C, Xin D, et al. Mesenchymal stem cell derived EVs mediate neuroprotection after spinal cord injury in rats via the microRNA-21-5p/FasL gene axis. Biomed Pharmacother. 2019;115:108818 pubmed publisher
Chen C, Gao R, Li M, Wang Q, Chen H, Zhang S, et al. Extracellular RNAs-TLR3 signaling contributes to cognitive decline in a mouse model of postoperative cognitive dysfunction. Brain Behav Immun. 2019;: pubmed publisher
Zhou X, Chu X, Xin D, Li T, Bai X, Qiu J, et al. L-Cysteine-Derived H2S Promotes Microglia M2 Polarization via Activation of the AMPK Pathway in Hypoxia-Ischemic Neonatal Mice. Front Mol Neurosci. 2019;12:58 pubmed publisher
Yu X, Wu J, Hu M, Wu J, Zhu Q, Yang Z, et al. Glutamate affects the CYP1B1- and CYP2U1-mediated hydroxylation of arachidonic acid metabolism via astrocytic mGlu5 receptor. Int J Biochem Cell Biol. 2019;110:111-121 pubmed publisher
Dong W, Sun Y, Cheng H, Yang B, Wang L, Jiang Z, et al. Dynamic cell type-specific expression of Nrf2 after traumatic brain injury in mice. Eur J Neurosci. 2019;: pubmed publisher
Lin Q, Wang W, Lin Y, Lin Z, Yu L, Kang Y, et al. Annexin A7 induction of neuronal apoptosis via effect on glutamate release in a rat model of subarachnoid hemorrhage. J Neurosurg. 2019;:1-11 pubmed publisher
Xiaoying L, Li T, Yu S, Jiusheng J, Jilin Z, Jiayi W, et al. Resistin-Inhibited Neural Stem Cell-Derived Astrocyte Differentiation Contributes to Permeability Destruction of the Blood-Brain Barrier. Neurochem Res. 2019;44:905-916 pubmed publisher
Fan J, Chen M, Wang X, Tian Z, Wang J, Fan D, et al. Targeting Smox Is Neuroprotective and Ameliorates Brain Inflammation in Cerebral Ischemia/Reperfusion Rats. Toxicol Sci. 2019;168:381-393 pubmed publisher
Zhang X, Zhao H, Li D, Li H. Neuroprotective effects of matrix metalloproteinases in cerebral ischemic rats by promoting activation and migration of astrocytes and microglia. Brain Res Bull. 2019;146:136-142 pubmed publisher
Chen C, Zhou F, Zeng L, Jiang Z, Hu Z. Methylene blue offers neuroprotection after intracerebral hemorrhage in rats through the PI3K/Akt/GSK3β signaling pathway. J Cell Physiol. 2019;234:5304-5318 pubmed publisher
Song Q, Fan C, Wang P, Li Y, Yang M, Yu S. Hippocampal CA1 βCaMKII mediates neuroinflammatory responses via COX-2/PGE2 signaling pathways in depression. J Neuroinflammation. 2018;15:338 pubmed publisher
Yang Y, Tian X, Xu D, Zheng F, Lu X, Zhang Y, et al. GPR40 modulates epileptic seizure and NMDA receptor function. Sci Adv. 2018;4:eaau2357 pubmed publisher
Pang J, Peng J, Matei N, Yang P, Kuai L, Wu Y, et al. Apolipoprotein E Exerts a Whole-Brain Protective Property by Promoting M1? Microglia Quiescence After Experimental Subarachnoid Hemorrhage in Mice. Transl Stroke Res. 2018;9:654-668 pubmed publisher
Li J, Hu X, Zhou F, Li S, Lin Y, Qi W, et al. Limb remote ischemic postconditioning protects integrity of the blood-brain barrier after stroke. Neural Regen Res. 2018;13:1585-1593 pubmed publisher
Xin D, Chu X, Bai X, Ma W, Yuan H, Qiu J, et al. l-Cysteine suppresses hypoxia-ischemia injury in neonatal mice by reducing glial activation, promoting autophagic flux and mediating synaptic modification via H2S formation. Brain Behav Immun. 2018;73:222-234 pubmed publisher
Du B, Ding Y, Xiao X, Ren H, Su B, Qi J. CD4+ αβ T cell infiltration into the leptomeninges of lumbar dorsal roots contributes to the transition from acute to chronic mechanical allodynia after adult rat tibial nerve injuries. J Neuroinflammation. 2018;15:81 pubmed publisher
Zhu Z, Liu J, Li K, Zheng J, Xiong Z. KPNB1 inhibition disrupts proteostasis and triggers unfolded protein response-mediated apoptosis in glioblastoma cells. Oncogene. 2018;37:2936-2952 pubmed publisher
Xu Y, Zhang H, Pan B, Zhang S, Wang S, Niu Q. Transcriptome-Wide Identification of Differentially Expressed Genes and Long Non-coding RNAs in Aluminum-Treated Rat Hippocampus. Neurotox Res. 2018;34:220-232 pubmed publisher
Liu C, Sun R, Huang J, Zhang D, Huang D, Qi W, et al. The BAF45D Protein Is Preferentially Expressed in Adult Neurogenic Zones and in Neurons and May Be Required for Retinoid Acid Induced PAX6 Expression. Front Neuroanat. 2017;11:94 pubmed publisher
Li Y, Wang L, Zhang X, Huang M, Li S, Wang X, et al. Inhibition of Cdk5 rejuvenates inhibitory circuits and restores experience-dependent plasticity in adult visual cortex. Neuropharmacology. 2018;128:207-220 pubmed publisher
Zhu L, Chi T, Zhao X, Yang L, Song S, Lu Q, et al. Xanthoceraside modulates neurogenesis to ameliorate cognitive impairment in APP/PS1 transgenic mice. J Physiol Sci. 2018;68:555-565 pubmed publisher
Xiao X, Feng Y, Du B, Sun H, Ding Y, Qi J. Antibody incubation at 37°C improves fluorescent immunolabeling in free-floating thick tissue sections. Biotechniques. 2017;62:115-122 pubmed publisher
Ahmed M, Tucker D, Dong Y, Lu Y, Zhao N, Wang R, et al. Methylene Blue promotes cortical neurogenesis and ameliorates behavioral deficit after photothrombotic stroke in rats. Neuroscience. 2016;336:39-48 pubmed publisher
He G, Xu W, Tong L, Li S, Su S, Tan X, et al. Gadd45b prevents autophagy and apoptosis against rat cerebral neuron oxygen-glucose deprivation/reperfusion injury. Apoptosis. 2016;21:390-403 pubmed publisher
Yin F, Guo L, Meng C, Liu Y, Lu R, Li P, et al. Transplantation of mesenchymal stem cells exerts anti-apoptotic effects in adult rats after spinal cord ischemia-reperfusion injury. Brain Res. 2014;1561:1-10 pubmed publisher
product information
CatalogNo :
60190-1-Ig
AntigenName :
GFAP
Package :
150UL
Price :
299 USD
Exsists20ul :
20ul trial size available
FullName :
glial fibrillary acidic protein
Immunogen :
Recombinant Protein
Species :
human, mouse, pig, rabbit, rat
Host :
Mouse
IsConjugated :
Unconjugated
AntigenSpecies :
human
CloneNo :
4B2E10
Application :
WB, IP, IHC, ELISA
Clonlity :
Monoclonal
IsoType :
IgG2a
Synonyms :
GFAP
PrimaryOrSecondary :
Primary
AntibodyBuffer :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
GenBankNo :
BC013596
Category :
Binding Proteins;Cell/Tissue Markers;Cytoskeleton/Scaffold Proteins;
PurifyMethod :
Protein A purification
NewAb :
False
IsSellable :
True
AppTiter :
IHC 1:5000 ; IP 1:1000 ; WB 1:100000 ;
company information
Proteintech Group
2201 W. Campbell Park Dr. STE12
Chicago, IL 60612
Proteintech@ptglab.com
https://www.ptglab.com
1-312-455-8498
headquarters: USA
At Proteintech, we produce every single antibody we sell; we do not rely on or supply to any other antibody providers: our products are unique and we are 100% accountable for each one. We realize this accountability by validating in-house, providing extensive technical support and guaranteeing your success: in addition to helping you troubleshoot your experiment, we will offer you a full cash refund if you are in any way dissatisfied. We can guarantee satisfaction because we have confidence in our products, confidence cultivated by the science behind our antibodies: we make them using as much of the native protein as possible, and purifying them using affinity purification with the original antigen. We carry out antibody production over a 102-day period, which allows for better antigen fitting to MHC molecules and affinity maturation in the host. This approach results in higher affinity antibodies with greater sensitivity, which you can use in any application and in multiple species.
You can only buy Proteintech antibodies directly from Proteintech or via one of its approved distributors — when you receive your antibody and see the Proteintech logo on the vial, know that you hold something that is truly unique.