This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Proteintech Group
product type :
antibody
product name :
CXCR4
catalog :
60042-1-Ig
quantity :
150UL
price :
299 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
4B5E4
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, flow cytometry
citations: 14
Published Application/Species/Sample/DilutionReference
  • western blot; human; loading ...; fig 2c
Bando H, Pradipta A, Iwanaga S, Okamoto T, Okuzaki D, Tanaka S, et al. CXCR4 regulates Plasmodium development in mouse and human hepatocytes. J Exp Med. 2019;: pubmed publisher
Zhou J, Le K, Xu M, Ming J, Yang W, Zhang Q, et al. CXCR4 Antagonist AMD3100 Reverses the Resistance to Tamoxifen in Breast Cancer via Inhibiting AKT Phosphorylation. Mol Ther Oncolytics. 2020;18:161-170 pubmed publisher
Yang L, Liu Q, Zhang X, Liu X, Zhou B, Chen J, et al. DNA of neutrophil extracellular traps promotes cancer metastasis via CCDC25. Nature. 2020;583:133-138 pubmed publisher
Yang M, Zeng C, Li P, Qian L, Ding B, Huang L, et al. Impact of CXCR4 and CXCR7 knockout by CRISPR/Cas9 on the function of triple-negative breast cancer cells. Onco Targets Ther. 2019;12:3849-3858 pubmed publisher
Shi W, Zhao J, Yuan R, Lu Y, Xin Q, Liu Y, et al. Combination of Ligusticum Chuanxiong and Radix Paeonia Promotes Angiogenesis in Ischemic Myocardium through Notch Signalling and Mobilization of Stem Cells. Evid Based Complement Alternat Med. 2019;2019:7912402 pubmed publisher
Cheng Y, Yin B, Hou T, Chen T, Ping J. The overexpression of GRASP might inhibit cell proliferation and invasion in hepatocellular carcinoma. J Cell Physiol. 2019;: pubmed publisher
Wu Y, Xu W, Hou J, Liu Y, Li R, Liu J, et al. Porphyromonas gingivalis-Induced MIF Regulates Intercellular Adhesion Molecule-1 Expression in EA.hy926 Cells and Monocyte-Endothelial Cell Adhesion Through the Receptors CD74 and CXCR4. Inflammation. 2019;42:874-883 pubmed publisher
Luo Y, Mohsin A, Xu C, Wang Q, Hang H, Zhuang Y, et al. Co-culture with TM4 cells enhances the proliferation and migration of rat adipose-derived mesenchymal stem cells with high stemness. Cytotechnology. 2018;70:1409-1422 pubmed publisher
Yang N, Ding Y, Zhang Y, Wang B, Zhao X, Cheng K, et al. Surface Functionalization of Polymeric Nanoparticles with Umbilical Cord-Derived Mesenchymal Stem Cell Membrane for Tumor-Targeted Therapy. ACS Appl Mater Interfaces. 2018;10:22963-22973 pubmed publisher
Shi A, Shi H, Dong L, Xu S, Jia M, Guo X, et al. CXCR7 as a chemokine receptor for SDF-1 promotes gastric cancer progression via MAPK pathways. Scand J Gastroenterol. 2017;52:745-753 pubmed publisher
Mitsui Y, Shiina H, Kato T, Maekawa S, Hashimoto Y, Shiina M, et al. Versican Promotes Tumor Progression, Metastasis and Predicts Poor Prognosis in Renal Carcinoma. Mol Cancer Res. 2017;15:884-895 pubmed publisher
Semba H, Takeda N, Isagawa T, Sugiura Y, Honda K, Wake M, et al. HIF-1?-PDK1 axis-induced active glycolysis plays an essential role in macrophage migratory capacity. Nat Commun. 2016;7:11635 pubmed publisher
Liu R, Wang W, Dai B, Liu Y, Zhang Y. Taspine derivative TAS9 regulates cell growth and metastasis of human hepatocellular carcinoma. Mol Med Rep. 2015;12:7735-41 pubmed publisher
Zhang Y, Zhan Y, Zhang D, Dai B, Ma W, Qi J, et al. Eupolyphaga sinensis walker displays inhibition on hepatocellular carcinoma through regulating cell growth and metastasis signaling. Sci Rep. 2014;4:5518 pubmed publisher
product information
CatalogNo :
60042-1-Ig
AntigenName :
CXCR4
Package :
150UL
Price :
299 USD
Exsists20ul :
20ul trial size available
FullName :
chemokine (C-X-C motif) receptor 4
Immunogen :
Recombinant Protein
Species :
human, mouse
Host :
Mouse
IsConjugated :
Unconjugated
AntigenSpecies :
human
CloneNo :
4B5E4
Application :
WB, IHC, IF, FC, ELISA
Clonlity :
Monoclonal
IsoType :
IgM
Synonyms :
CD184, CXC R4, CXCR 4, CXCR4, CXCR4B, D2S201E, FB22, Fusin, HM89, HSY3RR, LAP3, LCR1, LESTR, SDF 1 receptor, WHIM
PrimaryOrSecondary :
Primary
AntibodyBuffer :
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
GenBankNo :
BC020968
Category :
Apoptosis;Binding Proteins;Cytoskeleton/Scaffold Proteins;Development;Disease Related;Immunology;Membrane Proteins;Signal transduction;Stem Cells;
PurifyMethod :
Antigen affinity purification
NewAb :
False
IsSellable :
True
Feature :
siRNA
AppTiter :
FC 1:0 ; WB 1:1000 ;
company information
Proteintech Group
2201 W. Campbell Park Dr. STE12
Chicago, IL 60612
Proteintech@ptglab.com
https://www.ptglab.com
1-312-455-8498
headquarters: USA
At Proteintech, we produce every single antibody we sell; we do not rely on or supply to any other antibody providers: our products are unique and we are 100% accountable for each one. We realize this accountability by validating in-house, providing extensive technical support and guaranteeing your success: in addition to helping you troubleshoot your experiment, we will offer you a full cash refund if you are in any way dissatisfied. We can guarantee satisfaction because we have confidence in our products, confidence cultivated by the science behind our antibodies: we make them using as much of the native protein as possible, and purifying them using affinity purification with the original antigen. We carry out antibody production over a 102-day period, which allows for better antigen fitting to MHC molecules and affinity maturation in the host. This approach results in higher affinity antibodies with greater sensitivity, which you can use in any application and in multiple species.
You can only buy Proteintech antibodies directly from Proteintech or via one of its approved distributors — when you receive your antibody and see the Proteintech logo on the vial, know that you hold something that is truly unique.