This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Proteintech Group
product type :
antibody
product name :
CYTB
catalog :
55090-1-AP
quantity :
150UL
price :
299 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, ELISA, immunohistochemistry
citations: 26
Published Application/Species/Sample/DilutionReference
  • western blot; human; 1:1000; loading ...; fig s2e, s2g
Richter U, Ng K, Suomi F, Marttinen P, Turunen T, Jackson C, et al. Mitochondrial stress response triggered by defects in protein synthesis quality control. Life Sci Alliance. 2019;2: pubmed publisher
  • western blot; human; fig 6a
Meng F, Cang X, Peng Y, Li R, Zhang Z, Li F, et al. Biochemical Evidence for a Nuclear Modifier Allele (A10S) in TRMU (Methylaminomethyl-2-thiouridylate-methyltransferase) Related to Mitochondrial tRNA Modification in the Phenotypic Manifestation of Deafness-associated 12S rRNA Mutation. J Biol Chem. 2017;292:2881-2892 pubmed publisher
  • western blot; human; fig 5
Jiang P, Wang M, Xue L, Xiao Y, Yu J, Wang H, et al. A Hypertension-Associated tRNAAla Mutation Alters tRNA Metabolism and Mitochondrial Function. Mol Cell Biol. 2016;36:1920-30 pubmed publisher
Ma Y, Zhu S, Lv T, Gu X, Feng H, Zhen J, et al. SQSTM1/p62 Controls mtDNA Expression and Participates in Mitochondrial Energetic Adaption via MRPL12. iScience. 2020;23:101428 pubmed publisher
Zhang S, Reljic B, Liang C, Kerouanton B, Francisco J, Peh J, et al. Mitochondrial peptide BRAWNIN is essential for vertebrate respiratory complex III assembly. Nat Commun. 2020;11:1312 pubmed publisher
Li K, Wu L, Liu J, Lin W, Qi Q, Zhao T. Maternally Inherited Diabetes Mellitus Associated with a Novel m.15897G>A Mutation in Mitochondrial tRNAThr Gene. J Diabetes Res. 2020;2020:2057187 pubmed publisher
Gong S, Wang X, Meng F, Cui L, Yi Q, Zhao Q, et al. Overexpression of mitochondrial histidyl-tRNA synthetase restores mitochondrial dysfunction caused by a deafness-associated tRNAHis mutation. J Biol Chem. 2020;295:940-954 pubmed publisher
Zhuang X, Chen Y, Wu Z, Xu Q, Chen M, Shao M, et al. Mitochondrial miR-181a-5p promotes glucose metabolism reprogramming in liver cancer by regulating the electron transport chain. Carcinogenesis. 2019;: pubmed publisher
Zhao X, Cui L, Xiao Y, Mao Q, Aishanjiang M, Kong W, et al. Hypertension-associated mitochondrial DNA 4401A>G mutation caused the aberrant processing of tRNAMet, all 8 tRNAs and ND6 mRNA in the light-strand transcript. Nucleic Acids Res. 2019;47:10340-10356 pubmed publisher
Fu R, Yang P, Li Z, Liu W, Amin S, Li Z. Avenanthramide A triggers potent ROS-mediated anti-tumor effects in colorectal cancer by directly targeting DDX3. Cell Death Dis. 2019;10:593 pubmed publisher
Iershov A, Nemazanyy I, Alkhoury C, Girard M, Barth E, Cagnard N, et al. The class 3 PI3K coordinates autophagy and mitochondrial lipid catabolism by controlling nuclear receptor PPARα. Nat Commun. 2019;10:1566 pubmed publisher
Jia Z, Zhang Y, Li Q, Ye Z, Liu Y, Fu C, et al. A coronary artery disease-associated tRNAThr mutation altered mitochondrial function, apoptosis and angiogenesis. Nucleic Acids Res. 2019;47:2056-2074 pubmed publisher
Wang L, Yan Z, Vihinen H, Eriksson O, Wang W, Soliymani R, et al. FAM92A1 is a BAR domain protein required for mitochondrial ultrastructure and function. J Cell Biol. 2019;218:97-111 pubmed publisher
Aulas A, Lyons S, Fay M, Anderson P, Ivanov P. Nitric oxide triggers the assembly of "type II" stress granules linked to decreased cell viability. Cell Death Dis. 2018;9:1129 pubmed publisher
Richter U, Evans M, Clark W, Marttinen P, Shoubridge E, Suomalainen A, et al. RNA modification landscape of the human mitochondrial tRNALys regulates protein synthesis. Nat Commun. 2018;9:3966 pubmed publisher
Zhang J, Ji Y, Lu Y, Fu R, Xu M, Liu X, et al. Leber's hereditary optic neuropathy (LHON)-associated ND5 12338T > C mutation altered the assembly and function of complex I, apoptosis and mitophagy. Hum Mol Genet. 2018;27:1999-2011 pubmed publisher
Meng F, He Z, Tang X, Zheng J, Jin X, Zhu Y, et al. Contribution of the tRNAIle 4317A→G mutation to the phenotypic manifestation of the deafness-associated mitochondrial 12S rRNA 1555A→G mutation. J Biol Chem. 2018;293:3321-3334 pubmed publisher
Zhang J, Ji Y, Liu X, Chen J, Wang B, Zhang M, et al. Leber's hereditary optic neuropathy caused by a mutation in mitochondrial tRNAThr in eight Chinese pedigrees. Mitochondrion. 2018;42:84-91 pubmed publisher
Zhou M, Xue L, Chen Y, Li H, He Q, Wang B, et al. A hypertension-associated mitochondrial DNA mutation introduces an m1G37 modification into tRNAMet, altering its structure and function. J Biol Chem. 2018;293:1425-1438 pubmed publisher
Glasgow R, Thompson K, Barbosa I, He L, Alston C, Deshpande C, et al. Novel GFM2 variants associated with early-onset neurological presentations of mitochondrial disease and impaired expression of OXPHOS subunits. Neurogenetics. 2017;18:227-235 pubmed publisher
Zhou M, Wang M, Xue L, Lin Z, He Q, Shi W, et al. A hypertension-associated mitochondrial DNA mutation alters the tertiary interaction and function of tRNALeu(UUR). J Biol Chem. 2017;292:13934-13946 pubmed publisher
You Y, Zhang Y, Lu Y, Hu K, Qu X, Liu Y, et al. Protein profiling and functional analysis of liver mitochondria from rats with nonalcoholic steatohepatitis. Mol Med Rep. 2017;16:2379-2388 pubmed publisher
Chen X, Nie Z, Wang F, Wang J, Liu X, Zheng J, et al. Late onset nonsyndromic hearing loss in a Dongxiang Chinese family is associated with the 593T>C variant in the mitochondrial tRNAPhe gene. Mitochondrion. 2017;35:111-118 pubmed publisher
Wang M, Peng Y, Zheng J, Zheng B, Jin X, Liu H, et al. A deafness-associated tRNAAsp mutation alters the m1G37 modification, aminoacylation and stability of tRNAAsp and mitochondrial function. Nucleic Acids Res. 2016;44:10974-10985 pubmed
Wang M, Liu H, Zheng J, Chen B, Zhou M, Fan W, et al. A Deafness- and Diabetes-associated tRNA Mutation Causes Deficient Pseudouridinylation at Position 55 in tRNAGlu and Mitochondrial Dysfunction. J Biol Chem. 2016;291:21029-21041 pubmed
Jiang P, Jin X, Peng Y, Wang M, Liu H, Liu X, et al. The exome sequencing identified the mutation in YARS2 encoding the mitochondrial tyrosyl-tRNA synthetase as a nuclear modifier for the phenotypic manifestation of Leber's hereditary optic neuropathy-associated mitochondrial DNA mutation. Hum Mol Genet. 2016;25:584-96 pubmed publisher
product information
CatalogNo :
55090-1-AP
AntigenName :
CYTB
Package :
150UL
Price :
299 USD
Exsists20ul :
20ul trial size available
FullName :
cytochrome b
Immunogen :
Peptide
Species :
human, mouse, rat
Host :
Rabbit
IsConjugated :
Unconjugated
AntigenSpecies :
human
Application :
WB, IHC, ELISA
Clonlity :
Polyclonal
IsoType :
IgG
Synonyms :
COB, Complex III subunit 3, Complex III subunit III, CYTB, cytochrome b, MT CYB, MTCYB
PrimaryOrSecondary :
Primary
AntibodyBuffer :
0.1M NaHCO3, 0.1M glycine, 0.02% sodium azide and 50% glycerol pH 7.3.
GenBankNo :
YP_003024038
Category :
Binding Proteins;Cytoskeleton/Scaffold Proteins;Membrane Proteins;Metabolism;Transport/Trafficking;
PurifyMethod :
Antigen affinity purification
NewAb :
False
IsSellable :
True
AppTiter :
IHC 1:200 ; WB 1:600 ;
company information
Proteintech Group
2201 W. Campbell Park Dr. STE12
Chicago, IL 60612
Proteintech@ptglab.com
https://www.ptglab.com
1-312-455-8498
headquarters: USA
At Proteintech, we produce every single antibody we sell; we do not rely on or supply to any other antibody providers: our products are unique and we are 100% accountable for each one. We realize this accountability by validating in-house, providing extensive technical support and guaranteeing your success: in addition to helping you troubleshoot your experiment, we will offer you a full cash refund if you are in any way dissatisfied. We can guarantee satisfaction because we have confidence in our products, confidence cultivated by the science behind our antibodies: we make them using as much of the native protein as possible, and purifying them using affinity purification with the original antigen. We carry out antibody production over a 102-day period, which allows for better antigen fitting to MHC molecules and affinity maturation in the host. This approach results in higher affinity antibodies with greater sensitivity, which you can use in any application and in multiple species.
You can only buy Proteintech antibodies directly from Proteintech or via one of its approved distributors — when you receive your antibody and see the Proteintech logo on the vial, know that you hold something that is truly unique.