This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Proteintech Group
product type :
antibody
product name :
MTCO2
catalog :
55070-1-AP
quantity :
150UL
price :
299 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, zebrafish
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry
citations: 36
Published Application/Species/Sample/DilutionReference
  • western blot; zebrafish ; loading ...; fig 5a
Chen D, Zhang Z, Chen C, Yao S, Yang Q, Li F, et al. Deletion of Gtpbp3 in zebrafish revealed the hypertrophic cardiomyopathy manifested by aberrant mitochondrial tRNA metabolism. Nucleic Acids Res. 2019;47:5341-5355 pubmed publisher
  • western blot; human; loading ...; fig 3c
Liang K, Li N, Wang X, Dai J, Liu P, Wang C, et al. Cryo-EM structure of human mitochondrial trifunctional protein. Proc Natl Acad Sci U S A. 2018;115:7039-7044 pubmed publisher
Gao K, Cheng M, Zuo X, Lin J, Hoogewijs K, Murphy M, et al. Active RNA interference in mitochondria. Cell Res. 2020;: pubmed publisher
Ma Y, Zhu S, Lv T, Gu X, Feng H, Zhen J, et al. SQSTM1/p62 Controls mtDNA Expression and Participates in Mitochondrial Energetic Adaption via MRPL12. iScience. 2020;23:101428 pubmed publisher
Lou F, Sun Y, Xu Z, Niu L, Wang Z, Deng S, et al. Excessive Polyamine Generation in Keratinocytes Promotes Self-RNA Sensing by Dendritic Cells in Psoriasis. Immunity. 2020;53:204-216.e10 pubmed publisher
Zhao Q, Tian Z, Zhou G, Niu Q, Chen J, Li P, et al. SIRT1-dependent mitochondrial biogenesis supports therapeutic effects of resveratrol against neurodevelopment damage by fluoride. Theranostics. 2020;10:4822-4838 pubmed publisher
Tian N, Liu Q, Li Y, Tong L, Lu Y, Zhu Y, et al. Transketolase Deficiency in Adipose Tissues Protects Mice From Diet-Induced Obesity by Promoting Lipolysis. Diabetes. 2020;69:1355-1367 pubmed publisher
Liu L, Wang F, Tong Y, Li L, Liu Y, Gao W. Pentamidine inhibits prostate cancer progression via selectively inducing mitochondrial DNA depletion and dysfunction. Cell Prolif. 2019;:e12718 pubmed publisher
Meng F, Wu L, Dong L, Mitchell A, James Block C, Liu J, et al. EGFL9 promotes breast cancer metastasis by inducing cMET activation and metabolic reprogramming. Nat Commun. 2019;10:5033 pubmed publisher
Zhuang X, Chen Y, Wu Z, Xu Q, Chen M, Shao M, et al. Mitochondrial miR-181a-5p promotes glucose metabolism reprogramming in liver cancer by regulating the electron transport chain. Carcinogenesis. 2019;: pubmed publisher
Fu R, Yang P, Li Z, Liu W, Amin S, Li Z. Avenanthramide A triggers potent ROS-mediated anti-tumor effects in colorectal cancer by directly targeting DDX3. Cell Death Dis. 2019;10:593 pubmed publisher
Tian X, Zheng P, Zhou C, Wang X, Ma H, Ma W, et al. DIPK2A promotes STX17- and VAMP7-mediated autophagosome-lysosome fusion by binding to VAMP7B. Autophagy. 2019;:1-14 pubmed publisher
Lin T, Chen S, Chuang Y, Lan M, Chuang J, Wang P, et al. Mitochondrial Transfer of Wharton's Jelly Mesenchymal Stem Cells Eliminates Mutation Burden and Rescues Mitochondrial Bioenergetics in Rotenone-Stressed MELAS Fibroblasts. Oxid Med Cell Longev. 2019;2019:9537504 pubmed publisher
Zeng Y, Pan Q, Wang X, Li D, Lin Y, Man F, et al. Impaired Mitochondrial Fusion and Oxidative Phosphorylation Triggered by High Glucose Is Mediated by Tom22 in Endothelial Cells. Oxid Med Cell Longev. 2019;2019:4508762 pubmed publisher
Shan C, Gong Y, Zhuang Q, Hou Y, Wang S, Zhu Q, et al. Protective effects of β- nicotinamide adenine dinucleotide against motor deficits and dopaminergic neuronal damage in a mouse model of Parkinson's disease. Prog Neuropsychopharmacol Biol Psychiatry. 2019;94:109670 pubmed publisher
Wang K, Ma H, Liu H, Ye W, Li Z, Cheng L, et al. The Glycoprotein and Nucleocapsid Protein of Hantaviruses Manipulate Autophagy Flux to Restrain Host Innate Immune Responses. Cell Rep. 2019;27:2075-2091.e5 pubmed publisher
Zhao Y, Sun X, Hu D, Prosdocimo D, Hoppel C, Jain M, et al. ATAD3A oligomerization causes neurodegeneration by coupling mitochondrial fragmentation and bioenergetics defects. Nat Commun. 2019;10:1371 pubmed publisher
Wu H, Wang Y, Li W, Chen H, Du L, Liu D, et al. Deficiency of mitophagy receptor FUNDC1 impairs mitochondrial quality and aggravates dietary-induced obesity and metabolic syndrome. Autophagy. 2019;:1-17 pubmed publisher
Takahashi K, Miura Y, Ohsawa I, Shirasawa T, Takahashi M. In vitro rejuvenation of brain mitochondria by the inhibition of actin polymerization. Sci Rep. 2018;8:15585 pubmed publisher
Tang Y, Huang W, Song Q, Zheng X, He R, Liu J. Paeonol Ameliorates Ovalbumin-Induced Asthma through the Inhibition of TLR4/NF-κB and MAPK Signaling. Evid Based Complement Alternat Med. 2018;2018:3063145 pubmed publisher
Zhang Q, Zhang L, Chen D, He X, Yao S, Zhang Z, et al. Deletion of Mtu1 (Trmu) in zebrafish revealed the essential role of tRNA modification in mitochondrial biogenesis and hearing function. Nucleic Acids Res. 2018;46:10930-10945 pubmed publisher
Paulo E, Wu D, Wang Y, Zhang Y, Wu Y, Swaney D, et al. Sympathetic inputs regulate adaptive thermogenesis in brown adipose tissue through cAMP-Salt inducible kinase axis. Sci Rep. 2018;8:11001 pubmed publisher
Ziegler P, Bollrath J, Pallangyo C, Matsutani T, Canli O, De Oliveira T, et al. Mitophagy in Intestinal Epithelial Cells Triggers Adaptive Immunity during Tumorigenesis. Cell. 2018;174:88-101.e16 pubmed publisher
Markantone D, Towheed A, Crain A, Collins J, Celotto A, Palladino M. Protein coding mitochondrial-targeted RNAs rescue mitochondrial disease in vivo. Neurobiol Dis. 2018;117:203-210 pubmed publisher
Masand R, Paulo E, Wu D, Wang Y, Swaney D, Jimenez Morales D, et al. Proteome Imbalance of Mitochondrial Electron Transport Chain in Brown Adipocytes Leads to Metabolic Benefits. Cell Metab. 2018;27:616-629.e4 pubmed publisher
Télot L, Rousseau E, Lesuisse E, García C, Morlet B, Léger T, et al. Quantitative proteomics in Friedreich's ataxia B-lymphocytes: A valuable approach to decipher the biochemical events responsible for pathogenesis. Biochim Biophys Acta Mol Basis Dis. 2018;1864:997-1009 pubmed publisher
Li X, Xiong X, Zhang M, Wang K, Chen Y, Zhou J, et al. Base-Resolution Mapping Reveals Distinct m1A Methylome in Nuclear- and Mitochondrial-Encoded Transcripts. Mol Cell. 2017;68:993-1005.e9 pubmed publisher
Hu D, Cao S, Zhang G, Xiao Y, Liu S, Shang Y. Florfenicol-induced Mitochondrial Dysfunction Suppresses Cell Proliferation and Autophagy in Fibroblasts. Sci Rep. 2017;7:13554 pubmed publisher
Shanshan Y, Beibei J, Li T, Minna G, Shipeng L, Li P, et al. Phospholipase A2 of Peroxiredoxin 6 Plays a Critical Role in Cerebral Ischemia/Reperfusion Inflammatory Injury. Front Cell Neurosci. 2017;11:99 pubmed publisher
Duchesne A, Vaiman A, Castille J, Beauvallet C, Gaignard P, Floriot S, et al. Bovine and murine models highlight novel roles for SLC25A46 in mitochondrial dynamics and metabolism, with implications for human and animal health. PLoS Genet. 2017;13:e1006597 pubmed publisher
Martinez Lyons A, Ardissone A, Reyes A, Robinson A, Moroni I, Ghezzi D, et al. COA7 (C1orf163/RESA1) mutations associated with mitochondrial leukoencephalopathy and cytochrome c oxidase deficiency. J Med Genet. 2016;53:846-849 pubmed publisher
Wang S, Xu H, Xin Y, Li M, Fu W, Wang Y, et al. Neuroprotective effects of Kaempferide-7-O-(4?-O-acetylrhamnosyl)-3-O-rutinoside on cerebral ischemia-reperfusion injury in rats. Eur J Pharmacol. 2016;788:335-342 pubmed publisher
Di Nottia M, Masciullo M, Verrigni D, Petrillo S, Modoni A, Rizzo V, et al. DJ-1 modulates mitochondrial response to oxidative stress: clues from a novel diagnosis of PARK7. Clin Genet. 2017;92:18-25 pubmed publisher
Jiang X, Li L, Ying Z, Pan C, Huang S, Li L, et al. A Small Molecule That Protects the Integrity of the Electron Transfer Chain Blocks the Mitochondrial Apoptotic Pathway. Mol Cell. 2016;63:229-239 pubmed publisher
Radhakrishnan P, Ruh N, Harnoss J, Kiss J, Mollenhauer M, Scherr A, et al. Prolyl Hydroxylase 3 Attenuates MCL-1-Mediated ATP Production to Suppress the Metastatic Potential of Colorectal Cancer Cells. Cancer Res. 2016;76:2219-30 pubmed publisher
Zhang J, Wang C, Chen X, Takada M, Fan C, Zheng X, et al. EglN2 associates with the NRF1-PGC1α complex and controls mitochondrial function in breast cancer. EMBO J. 2015;34:2953-70 pubmed publisher
product information
CatalogNo :
55070-1-AP
AntigenName :
MTCO2
Package :
150UL
Price :
299 USD
Exsists20ul :
20ul trial size available
FullName :
cytochrome c oxidase II
Immunogen :
Peptide
Species :
human, mouse, rat, zebrafish
Host :
Rabbit
IsConjugated :
Unconjugated
AntigenSpecies :
human
Application :
WB, IP, IHC, IF, FC, ELISA
Clonlity :
Polyclonal
IsoType :
IgG
Synonyms :
COII, COX2, COXII, cytochrome c oxidase II, Cytochrome c oxidase subunit 2, MT CO2, MTCO2, mtcox2
PrimaryOrSecondary :
Primary
AntibodyBuffer :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
GenBankNo :
YP_003024029
Category :
Binding Proteins;Cytoskeleton/Scaffold Proteins;Membrane Proteins;Transport/Trafficking;
PurifyMethod :
Antigen affinity purification
NewAb :
False
IsSellable :
True
Feature :
siRNA
AppTiter :
FC 1:0 ; IF 1:50 ; IHC 1:50 ; IP 1:1000 ; WB 1:3000 ;
company information
Proteintech Group
2201 W. Campbell Park Dr. STE12
Chicago, IL 60612
Proteintech@ptglab.com
https://www.ptglab.com
1-312-455-8498
headquarters: USA
At Proteintech, we produce every single antibody we sell; we do not rely on or supply to any other antibody providers: our products are unique and we are 100% accountable for each one. We realize this accountability by validating in-house, providing extensive technical support and guaranteeing your success: in addition to helping you troubleshoot your experiment, we will offer you a full cash refund if you are in any way dissatisfied. We can guarantee satisfaction because we have confidence in our products, confidence cultivated by the science behind our antibodies: we make them using as much of the native protein as possible, and purifying them using affinity purification with the original antigen. We carry out antibody production over a 102-day period, which allows for better antigen fitting to MHC molecules and affinity maturation in the host. This approach results in higher affinity antibodies with greater sensitivity, which you can use in any application and in multiple species.
You can only buy Proteintech antibodies directly from Proteintech or via one of its approved distributors — when you receive your antibody and see the Proteintech logo on the vial, know that you hold something that is truly unique.