| Published Application/Species/Sample/Dilution | Reference | 
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| western blot; human; 1:1000; loading ...; fig 3e
 | Wang Q, Jia S, Jiao Y, Xu L, Wang D, Chen X, et al . SSRP1 influences colorectal cancer cell growth and apoptosis via the AKT pathway. Int J Med Sci. 2019;16:1573-1582 pubmed  publisher | 
|  | Cui Y, Song Y, Yan S, Cao M, Huang J, Jia D, et al . CUEDC1 inhibits epithelial-mesenchymal transition via the TβRI/Smad signaling pathway and suppresses tumor progression in non-small cell lung cancer. Aging (Albany NY). 2020;12:20047-20068 pubmed  publisher | 
|  | Feng Y, Tan B. LncRNA MALAT1 inhibits apoptosis of endometrial stromal cells through miR-126-5p-CREB1 axis by activating PI3K-AKT pathway. Mol Cell Biochem. 2020;: pubmed  publisher | 
|  | Ma S, Wang Y, Zhou X, Li Z, Zhang Z, Wang Y, et al . MG53 Protects hUC-MSCs against Inflammatory Damage and Synergistically Enhances Their Efficacy in Neuroinflammation Injured Brain through Inhibiting NLRP3/Caspase-1/IL-1β Axis. ACS Chem Neurosci. 2020;11:2590-2601 pubmed  publisher | 
|  | Fu G, Dai J, Li Z, Chen F, Liu L, Yi L, et al . The role of STAT3/p53 and PI3K-Akt-mTOR signaling pathway on DEHP-induced reproductive toxicity in pubertal male rat. Toxicol Appl Pharmacol. 2020;404:115151 pubmed  publisher | 
|  | Sun Y, Chen Y, Xu M, Liu C, Shang H, Wang C. Shenmai Injection Supresses Glycolysis and Enhances Cisplatin Cytotoxicity in Cisplatin-Resistant A549/DDP Cells via the AKT-mTOR-c-Myc Signaling Pathway. Biomed Res Int. 2020;2020:9243681 pubmed  publisher | 
|  | Kuang M, Yang M, Li L, Li C, Wang G. UFM1-Specific Ligase 1 Ligating Enzyme 1 Mediates Milk Protein and Fat Synthesis-Related Gene Expression via the JNK Signaling Pathway in Mouse Mammary Epithelial Cells. Oxid Med Cell Longev. 2020;2020:4045674 pubmed  publisher | 
|  | Yuan M, Yang X, Duscher D, Xiong H, Ren S, Xu X, et al . Overexpression of microRNA-21-5p prevents the oxidative stress-induced apoptosis of RSC96 cells by suppressing autophagy. Life Sci. 2020;256:118022 pubmed  publisher | 
|  | Han B, Jiang L, Jiang P, Zhou D, Jia X, Li X, et al . Daucosterol linolenate from Sweet Potato Suppresses MCF7-Xenograft-Tumor Growth through Regulating PI3K/AKT Pathway. Planta Med. 2020;86:767-775 pubmed  publisher | 
|  | Li L, Peng X, Guo L, Zhao Y, Cheng Q. Sepsis causes heart injury through endoplasmic reticulum stress-mediated apoptosis signaling pathway. Int J Clin Exp Pathol. 2020;13:964-971 pubmed | 
|  | Zhou D, Yang W, Zhang Y, Xie J, Ma L, Yang H, et al . Sodium tanshinone IIA sulfonate prevents radiation-induced damage in primary rat cardiac fibroblasts. Chin J Nat Med. 2020;18:436-445 pubmed  publisher | 
|  | Wu J, He J, Tian X, Li H, Wen Y, Shao Q, et al . Upregulation of miRNA-9-5p Promotes Angiogenesis after Traumatic Brain Injury by Inhibiting Ptch-1. Neuroscience. 2020;440:160-174 pubmed  publisher | 
|  | Wang W, Zheng L, Xu L, Tu J, Gu X. Pinocembrin mitigates depressive-like behaviors induced by chronic unpredictable mild stress through ameliorating neuroinflammation and apoptosis. Mol Med. 2020;26:53 pubmed  publisher | 
|  | Ma C, Wang X, Xu T, Zhang S, Liu S, Zhai C, et al . An Integrative Pharmacology-Based Analysis of Refined Qingkailing Injection Against Cerebral Ischemic Stroke: A Novel Combination of Baicalin, Geniposide, Cholic Acid, and Hyodeoxycholic Acid. Front Pharmacol. 2020;11:519 pubmed  publisher | 
|  | Xu A, Shang W, Wang Y, Sun X, Zhou B, Xie Y, et al . ALA protects against ERS-mediated apoptosis in a cochlear cell model with low citrate synthase expression. Arch Biochem Biophys. 2020;688:108402 pubmed  publisher | 
|  | Ge J, Huang Y, Zhang Y, Liu L, Gu T, Liu X, et al . Metformin Inhibits Propofol-Induced Apoptosis of Mouse Hippocampal Neurons HT-22 Through Downregulating Cav-1. Drug Des Devel Ther. 2020;14:1561-1569 pubmed  publisher | 
|  | Zeng Q, Zhang Y, Zhang W, Guo Q. Baicalein suppresses the proliferation and invasiveness of colorectal cancer cells by inhibiting Snail‑induced epithelial‑mesenchymal transition. Mol Med Rep. 2020;21:2544-2552 pubmed  publisher | 
|  | Deng Y, Yang L, Xie Q, Yang F, Li G, Zhang G, et al . Protein Kinase A Is Involved in Neuropathic Pain by Activating the p38MAPK Pathway to Mediate Spinal Cord Cell Apoptosis. Mediators Inflamm. 2020;2020:6420425 pubmed  publisher | 
|  | Shi B, Huang Y, Ni J, Chen J, Wei J, Gao H, et al . Qi Dan Li Xin pill improves chronic heart failure by regulating mTOR/p70S6k-mediated autophagy and inhibiting apoptosis. Sci Rep. 2020;10:6105 pubmed  publisher | 
|  | Sun Y, Lu F, Yu X, Wang B, Chen J, Lu F, et al . Exogenous H2S Promoted USP8 Sulfhydration to Regulate Mitophagy in the Hearts of db/db Mice. Aging Dis. 2020;11:269-285 pubmed  publisher | 
|  | Wang W, Hu X, Xia Z, Liu Z, Zhong Z, Lu Z, et al . Mild Hypothermia Attenuates Hepatic Ischemia-Reperfusion Injury through Regulating the JAK2/STAT3-CPT1a-Dependent Fatty Acid β-Oxidation. Oxid Med Cell Longev. 2020;2020:5849794 pubmed  publisher | 
|  | Luo J, Yang C, Luo X, Yang Y, Li J, Song B, et al . Chlorogenic acid attenuates cyclophosphamide-induced rat interstitial cystitis. Life Sci. 2020;254:117590 pubmed  publisher | 
|  | Cui G, Li L, Xu W, Wang M, Jiao D, Yao B, et al . Astaxanthin Protects Ochratoxin A-Induced Oxidative Stress and Apoptosis in the Heart via the Nrf2 Pathway. Oxid Med Cell Longev. 2020;2020:7639109 pubmed  publisher | 
|  | Luan Y, Cui K, Tang Z, Ruan Y, Liu K, Wang T, et al . Human Tissue Kallikrein 1 Improves Erectile Dysfunction of Streptozotocin-Induced Diabetic Rats by Inhibition of Excessive Oxidative Stress and Activation of the PI3K/AKT/eNOS Pathway. Oxid Med Cell Longev. 2020;2020:6834236 pubmed  publisher | 
|  | Jin W, Xue Y, Xue Y, Han X, Song Q, Zhang J, et al . Tannic acid ameliorates arsenic trioxide-induced nephrotoxicity, contribution of NF-κB and Nrf2 pathways. Biomed Pharmacother. 2020;126:110047 pubmed  publisher | 
|  | Xiong Y, Yin Q, Li J, He S. Oxidative Stress and Endoplasmic Reticulum Stress Are Involved in the Protective Effect of Alpha Lipoic Acid Against Heat Damage in Chicken Testes. Animals (Basel). 2020;10: pubmed  publisher | 
|  | Liu H, Zhang W, Fang Y, Yang H, Tian L, Li K, et al . Neurotoxicity of aluminum oxide nanoparticles and their mechanistic role in dopaminergic neuron injury involving p53-related pathways. J Hazard Mater. 2020;392:122312 pubmed  publisher | 
|  | Wang P, Zhao M, Chen Z, Wu G, Fujino M, Zhang C, et al . Hydrogen Gas Attenuates Hypoxic-Ischemic Brain Injury via Regulation of the MAPK/HO-1/PGC-1a Pathway in Neonatal Rats. Oxid Med Cell Longev. 2020;2020:6978784 pubmed  publisher | 
|  | Xu B, Zang S, Lang L, Lian S, Lu J, Li S, et al . Down-regulation of miR-383-5p suppresses apoptosis in oxidative stress rat hepatocytes by targeting Bcl2. J Anim Physiol Anim Nutr (Berl). 2020;: pubmed  publisher | 
|  | Chen G, Zhang X, Chen H, Lin H, Wu H, Lin H, et al . miR-22 represses osteoblast viability with ESR1 presenting a direct target and indirectly inactivating p38 MAPK/JNK signaling. J Gene Med. 2020;22:e3174 pubmed  publisher | 
|  | Shang Y, Wang Q, Li J, Zhao Q, Huang X, Dong H, et al . The Acetone Indigo Red Dehydrating Agent IF203 Induces HepG2 Cell Death Through Cell Cycle Arrest, Autophagy and Apoptosis. Onco Targets Ther. 2020;13:473-486 pubmed  publisher | 
|  | Shopit A, Niu M, Wang H, Tang Z, Li X, Tesfaldet T, et al . Protection of diabetes-induced kidney injury by phosphocreatine via the regulation of ERK/Nrf2/HO-1 signaling pathway. Life Sci. 2020;242:117248 pubmed  publisher | 
|  | Ying C, Ying L, Yanxia L, Le W, Lili C. High mobility group box 1 antibody represses autophagy and alleviates hippocampus damage in pilocarpine-induced mouse epilepsy model. Acta Histochem. 2020;122:151485 pubmed  publisher | 
|  | Pei G, Xu L, Huang W, Yin J. The protective role of microRNA-133b in restricting hippocampal neurons apoptosis and inflammatory injury in rats with depression by suppressing CTGF. Int Immunopharmacol. 2020;78:106076 pubmed  publisher | 
|  | Liu Q, Zhang S, Zhu D, Tang X, Che Y, Feng X. The parthenolide derivative ACT001 synergizes with low doses of L-DOPA to improve MPTP-induced Parkinson's disease in mice. Behav Brain Res. 2020;379:112337 pubmed  publisher | 
|  | Jin W, Zhang Y, Xue Y, Han X, Zhang X, Ma Z, et al . Crocin attenuates isoprenaline-induced myocardial fibrosis by targeting TLR4/NF-κB signaling: connecting oxidative stress, inflammation, and apoptosis. Naunyn Schmiedebergs Arch Pharmacol. 2020;393:13-23 pubmed  publisher | 
|  | Guo J, Fu W, Xiang M, Zhang Y, Zhou K, Xu C, et al . Notch1 Drives the Formation and Proliferation of Intrahepatic Cholangiocarcinoma. Curr Med Sci. 2019;39:929-937 pubmed  publisher | 
|  | Li Y, Chen H, Yang Y, Niu M, Wang J, Wu Y, et al . Danshen formula granule and salvianic acid A alleviate ethanol-induced neurotoxicity. J Nat Med. 2019;: pubmed  publisher | 
|  | Du Y, Qian B, Gao L, Tan P, Chen H, Wang A, et al . Aloin Preconditioning Attenuates Hepatic Ischemia/Reperfusion Injury via Inhibiting TLR4/MyD88/NF-κB Signal Pathway In Vivo and In Vitro. Oxid Med Cell Longev. 2019;2019:3765898 pubmed  publisher | 
|  | Guo X, Zhang Y, Lu C, Qu F, Jiang X. Protective effect of hyperoside on heart failure rats via attenuating myocardial apoptosis and inducing autophagy. Biosci Biotechnol Biochem. 2019;:1-11 pubmed  publisher | 
|  | Yang L, Jiang L, Jiang D, Liu B, Jin S. The protective effects of salvianolic acid A against hepatic ischemia-reperfusion injury via inhibiting expression of toll-like receptor 4 in rats. Arch Med Sci. 2019;15:1599-1607 pubmed  publisher | 
|  | Xu W, Zheng H, Yang R, Liu T, Yu W, Zheng X, et al . Mitochondrial NDUFA4L2 attenuates the apoptosis of nucleus pulposus cells induced by oxidative stress via the inhibition of mitophagy. Exp Mol Med. 2019;51:140 pubmed  publisher | 
|  | Liu W, Zhou Y, Liang R, Zhang Y. Inhibition of cyclin-dependent kinase 5 activity alleviates diabetes-related cognitive deficits. FASEB J. 2019;33:14506-14515 pubmed  publisher | 
|  | Song S, Chu L, Liang H, Chen J, Liang J, Huang Z, et al . Protective Effects of Dioscin Against Doxorubicin-Induced Hepatotoxicity Via Regulation of Sirt1/FOXO1/NF-κb Signal. Front Pharmacol. 2019;10:1030 pubmed  publisher | 
|  | Feng X, Xiong W, Yuan M, Zhan J, Zhu X, Wei Z, et al . Down-regulated microRNA-183 mediates the Jak/Stat signaling pathway to attenuate hippocampal neuron injury in epilepsy rats by targeting Foxp1. Cell Cycle. 2019;18:3206-3222 pubmed  publisher | 
|  | Zeng Z, Liu Y, Zheng W, Liu L, Yin H, Zhang S, et al . MicroRNA-129-5p alleviates nerve injury and inflammatory response of Alzheimer's disease via downregulating SOX6. Cell Cycle. 2019;18:3095-3110 pubmed  publisher | 
|  | He F, Dai R, Zhou X, Li X, Song X, Yan H, et al . Protective effect of 4-Methoxy benzyl alcohol on the neurovascular unit after cerebral ischemia reperfusion injury. Biomed Pharmacother. 2019;118:109260 pubmed  publisher | 
|  | Wu X, Kong Q, Zhan L, Qiu Z, Huang Q, Song X. TIPE2 ameliorates lipopolysaccharide-induced apoptosis and inflammation in acute lung injury. Inflamm Res. 2019;68:981-992 pubmed  publisher | 
|  | Feng C, Li D, Chen M, Jiang L, Liu X, Li Q, et al . Citreoviridin induces myocardial apoptosis through PPAR-γ-mTORC2-mediated autophagic pathway and the protective effect of thiamine and selenium. Chem Biol Interact. 2019;311:108795 pubmed  publisher | 
|  | Liu Y, Chen H, Zhang L, Zhang T, Ren X. The Association Between Thyroid Injury and Apoptosis, and Alterations of Bax, Bcl-2, and Caspase-3 mRNA/Protein Expression Induced by Nickel Sulfate in Wistar Rats. Biol Trace Elem Res. 2019;: pubmed  publisher | 
|  | Yang Q, Zhu J, Luo X, Li F, Cong L, Wang Y, et al . Melatonin attenuates cadmium-induced ovulatory dysfunction by suppressing endoplasmic reticulum stress and cell apoptosis. Reprod Biol Endocrinol. 2019;17:61 pubmed  publisher | 
|  | Cheng Y, Li J, Wang C, Yang H, Wang Y, Zhan T, et al . Inhibition of long non-coding RNA Malat1 attenuates high glucose-induced cardiomyocyte apoptosis via regulation of miR-181a-5p. Exp Anim. 2019;: pubmed  publisher | 
|  | Wang Y, Wu J, Li Y, Qi X. Polysaccharides of Fructus corni Improve Ovarian Function in Mice with Aging-Associated Perimenopause Symptoms. Evid Based Complement Alternat Med. 2019;2019:2089586 pubmed  publisher | 
|  | Huang X, Qiao F, Xue P. The protective role of microRNA-140-5p in synovial injury of rats with knee osteoarthritis via inactivating the TLR4/Myd88/NF-κB signaling pathway. Cell Cycle. 2019;18:2344-2358 pubmed  publisher | 
|  | Zhang H, Chen F, He S, Liang Y, Wang Z, Wang L, et al . In vivo tracking on longer retention of transplanted myocardin gene-modified adipose-derived stem cells to improve erectile dysfunction in diabetic rats. Stem Cell Res Ther. 2019;10:208 pubmed  publisher | 
|  | Xu W, Yang R, Zheng H, Yu W, Zheng X, Li B, et al . PGC-1α acts as an mediator of Sirtuin2 to protect annulus fibrosus from apoptosis induced by oxidative stress through restraining mitophagy. Int J Biol Macromol. 2019;136:1007-1017 pubmed  publisher | 
|  | Xu Y, Yao S, Gao D, Li W, Zheng D, Zhang Q. Effect of astaxanthin on apoptosis of rat renal tubular epithelial cells induced by iohexol. Am J Transl Res. 2019;11:3039-3047 pubmed | 
|  | Zhou L, Wang S, Cao L, Ren X, Li Y, Shao J, et al . Lead acetate induces apoptosis in Leydig cells by activating PPARγ/caspase-3/PARP pathway. Int J Environ Health Res. 2019;:1-11 pubmed  publisher | 
|  | Zhang Y, Chi X, Wang Z, Bi S, Wang Y, Shi F, et al . Protective effects of Panax notoginseng saponins on PME-Induced nephrotoxicity in mice. Biomed Pharmacother. 2019;116:108970 pubmed  publisher | 
|  | Sun X, Huang X, Zhu X, Liu L, Mo S, Wang H, et al . HBOA ameliorates CCl4-incuded liver fibrosis through inhibiting TGF-β1/Smads, NF-κB and ERK signaling pathways. Biomed Pharmacother. 2019;115:108901 pubmed  publisher | 
|  | Zhang J, Yao D, Zhang J, Song Y, Mo F, Chu X, et al . TGF-β mediates thoracic radiation-induced abscopal effects of testis injury in rat. Biochem Biophys Res Commun. 2019;: pubmed  publisher | 
|  | Luo T, Zeng X, Yang W, Zhang Y. Treatment with metformin prevents myocardial ischemia-reperfusion injury via STEAP4 signaling pathway. Anatol J Cardiol. 2019;21:261-271 pubmed  publisher | 
|  | Chen C, Jiang L, Zhang M, Pan X, Peng C, Huang W, et al . Isodunnianol alleviates doxorubicin-induced myocardial injury by activating protective autophagy. Food Funct. 2019;10:2651-2657 pubmed  publisher | 
|  | Dong S, Ji J, Hu L, Wang H. Dihydromyricetin alleviates acetaminophen-induced liver injury via the regulation of transformation, lipid homeostasis, cell death and regeneration. Life Sci. 2019;227:20-29 pubmed  publisher | 
|  | Yin F, Yan J, Zhao Y, Guo K, Zhang Z, Li A, et al . Bone marrow mesenchymal stem cells repair Cr (VI)- injured kidney by regulating mitochondria-mediated apoptosis and mitophagy mediated via the MAPK signaling pathway. Ecotoxicol Environ Saf. 2019;176:234-241 pubmed  publisher | 
|  | Zhang L, Liu Y, Huang Z, Nan L, Wang F, Zhou S, et al . Toxicity Effects of Methylene Blue on Rat Intervertebral Disc Annulus Fibrosus Cells. Pain Physician. 2019;22:155-164 pubmed | 
|  | Huang Z, Zheng Y, Li N, Cai S, Huang Y, Wang J, et al . Protective effects of specific cannabinoid receptor 2 agonist GW405833 on concanavalin A-induced acute liver injury in mice. Acta Pharmacol Sin. 2019;: pubmed  publisher | 
|  | Zhang Y, Gao J, Sun W, Wen X, Xi Y, Wang Y, et al . H2S restores the cardioprotective effects of ischemic post-conditioning by upregulating HB-EGF/EGFR signaling. Aging (Albany NY). 2019;11:1745-1758 pubmed  publisher | 
|  | Hu H, Wang C, Jin Y, Meng Q, Liu Q, Liu Z, et al . Catalpol Inhibits Homocysteine-induced Oxidation and Inflammation via Inhibiting Nox4/NF-κB and GRP78/PERK Pathways in Human Aorta Endothelial Cells. Inflammation. 2019;42:64-80 pubmed  publisher | 
|  | Deng J, Feng J, Liu T, Lu X, Wang W, Liu N, et al . Beraprost sodium preconditioning prevents inflammation, apoptosis, and autophagy during hepatic ischemia-reperfusion injury in mice via the P38 and JNK pathways. Drug Des Devel Ther. 2018;12:4067-4082 pubmed  publisher | 
|  | Zhao Y, Zhang H, Yang X, Zhang Y, Feng S, Yu F, et al . Fine Particulate Matter-Induced Exacerbation of Allergic Asthma via Activation of T-cell Immunoglobulin and Mucin Domain 1. Chin Med J (Engl). 2018;131:2461-2473 pubmed  publisher | 
|  | Zhao W, Che C, Liu K, Zhang J, Jiang N, Yuan K, et al . Fenretinide Inhibits Neutrophil Recruitment and IL-1β Production in Aspergillus fumigatus Keratitis. Cornea. 2018;37:1579-1585 pubmed  publisher | 
|  | Duan H, Wu Q, Yao X, Fan B, Shi H, Zhao C, et al . Nafamostat mesilate attenuates inflammation and apoptosis and promotes locomotor recovery after spinal cord injury. CNS Neurosci Ther. 2018;24:429-438 pubmed  publisher | 
|  | Zhang Y, Yang B, Zhao J, Li X, Zhang L, Zhai Z. Proteasome Inhibitor Carbobenzoxy-L-Leucyl-L-Leucyl-L-Leucinal (MG132) Enhances Therapeutic Effect of Paclitaxel on Breast Cancer by Inhibiting Nuclear Factor (NF)-κB Signaling. Med Sci Monit. 2018;24:294-304 pubmed | 
|  | Xu Y, Yao J, Zou C, Zhang H, Zhang S, Liu J, et al . Asiatic acid protects against hepatic ischemia/reperfusion injury by inactivation of Kupffer cells via PPAR?/NLRP3 inflammasome signaling pathway. Oncotarget. 2017;8:86339-86355 pubmed  publisher | 
|  | Chen Y, Li Y, Xu H, Li G, Ma Y, Pang Y. MORIN MITIGATES OXIDATIVE STRESS, APOPTOSIS AND INFLAMMATION IN CEREBRAL ISCHEMIC RATS. Afr J Tradit Complement Altern Med. 2017;14:348-355 pubmed  publisher | 
|  | Zhao S, Li L, Wang S, Yu C, Xiao B, Lin L, et al . H2O2 treatment or serum deprivation induces autophagy and apoptosis in naked mole-rat skin fibroblasts by inhibiting the PI3K/Akt signaling pathway. Oncotarget. 2016;7:84839-84850 pubmed  publisher |