This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Proteintech Group
product type :
antibody
product name :
Bcl2
catalog :
26593-1-AP
quantity :
150UL
price :
299 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry
citations: 77
Published Application/Species/Sample/DilutionReference
  • western blot; human; 1:1000; loading ...; fig 3e
Wang Q, Jia S, Jiao Y, Xu L, Wang D, Chen X, et al. SSRP1 influences colorectal cancer cell growth and apoptosis via the AKT pathway. Int J Med Sci. 2019;16:1573-1582 pubmed publisher
Cui Y, Song Y, Yan S, Cao M, Huang J, Jia D, et al. CUEDC1 inhibits epithelial-mesenchymal transition via the TβRI/Smad signaling pathway and suppresses tumor progression in non-small cell lung cancer. Aging (Albany NY). 2020;12:20047-20068 pubmed publisher
Feng Y, Tan B. LncRNA MALAT1 inhibits apoptosis of endometrial stromal cells through miR-126-5p-CREB1 axis by activating PI3K-AKT pathway. Mol Cell Biochem. 2020;: pubmed publisher
Ma S, Wang Y, Zhou X, Li Z, Zhang Z, Wang Y, et al. MG53 Protects hUC-MSCs against Inflammatory Damage and Synergistically Enhances Their Efficacy in Neuroinflammation Injured Brain through Inhibiting NLRP3/Caspase-1/IL-1β Axis. ACS Chem Neurosci. 2020;11:2590-2601 pubmed publisher
Fu G, Dai J, Li Z, Chen F, Liu L, Yi L, et al. The role of STAT3/p53 and PI3K-Akt-mTOR signaling pathway on DEHP-induced reproductive toxicity in pubertal male rat. Toxicol Appl Pharmacol. 2020;404:115151 pubmed publisher
Sun Y, Chen Y, Xu M, Liu C, Shang H, Wang C. Shenmai Injection Supresses Glycolysis and Enhances Cisplatin Cytotoxicity in Cisplatin-Resistant A549/DDP Cells via the AKT-mTOR-c-Myc Signaling Pathway. Biomed Res Int. 2020;2020:9243681 pubmed publisher
Kuang M, Yang M, Li L, Li C, Wang G. UFM1-Specific Ligase 1 Ligating Enzyme 1 Mediates Milk Protein and Fat Synthesis-Related Gene Expression via the JNK Signaling Pathway in Mouse Mammary Epithelial Cells. Oxid Med Cell Longev. 2020;2020:4045674 pubmed publisher
Yuan M, Yang X, Duscher D, Xiong H, Ren S, Xu X, et al. Overexpression of microRNA-21-5p prevents the oxidative stress-induced apoptosis of RSC96 cells by suppressing autophagy. Life Sci. 2020;256:118022 pubmed publisher
Han B, Jiang L, Jiang P, Zhou D, Jia X, Li X, et al. Daucosterol linolenate from Sweet Potato Suppresses MCF7-Xenograft-Tumor Growth through Regulating PI3K/AKT Pathway. Planta Med. 2020;86:767-775 pubmed publisher
Li L, Peng X, Guo L, Zhao Y, Cheng Q. Sepsis causes heart injury through endoplasmic reticulum stress-mediated apoptosis signaling pathway. Int J Clin Exp Pathol. 2020;13:964-971 pubmed
Zhou D, Yang W, Zhang Y, Xie J, Ma L, Yang H, et al. Sodium tanshinone IIA sulfonate prevents radiation-induced damage in primary rat cardiac fibroblasts. Chin J Nat Med. 2020;18:436-445 pubmed publisher
Wu J, He J, Tian X, Li H, Wen Y, Shao Q, et al. Upregulation of miRNA-9-5p Promotes Angiogenesis after Traumatic Brain Injury by Inhibiting Ptch-1. Neuroscience. 2020;440:160-174 pubmed publisher
Wang W, Zheng L, Xu L, Tu J, Gu X. Pinocembrin mitigates depressive-like behaviors induced by chronic unpredictable mild stress through ameliorating neuroinflammation and apoptosis. Mol Med. 2020;26:53 pubmed publisher
Ma C, Wang X, Xu T, Zhang S, Liu S, Zhai C, et al. An Integrative Pharmacology-Based Analysis of Refined Qingkailing Injection Against Cerebral Ischemic Stroke: A Novel Combination of Baicalin, Geniposide, Cholic Acid, and Hyodeoxycholic Acid. Front Pharmacol. 2020;11:519 pubmed publisher
Xu A, Shang W, Wang Y, Sun X, Zhou B, Xie Y, et al. ALA protects against ERS-mediated apoptosis in a cochlear cell model with low citrate synthase expression. Arch Biochem Biophys. 2020;688:108402 pubmed publisher
Ge J, Huang Y, Zhang Y, Liu L, Gu T, Liu X, et al. Metformin Inhibits Propofol-Induced Apoptosis of Mouse Hippocampal Neurons HT-22 Through Downregulating Cav-1. Drug Des Devel Ther. 2020;14:1561-1569 pubmed publisher
Zeng Q, Zhang Y, Zhang W, Guo Q. Baicalein suppresses the proliferation and invasiveness of colorectal cancer cells by inhibiting Snail‑induced epithelial‑mesenchymal transition. Mol Med Rep. 2020;21:2544-2552 pubmed publisher
Deng Y, Yang L, Xie Q, Yang F, Li G, Zhang G, et al. Protein Kinase A Is Involved in Neuropathic Pain by Activating the p38MAPK Pathway to Mediate Spinal Cord Cell Apoptosis. Mediators Inflamm. 2020;2020:6420425 pubmed publisher
Shi B, Huang Y, Ni J, Chen J, Wei J, Gao H, et al. Qi Dan Li Xin pill improves chronic heart failure by regulating mTOR/p70S6k-mediated autophagy and inhibiting apoptosis. Sci Rep. 2020;10:6105 pubmed publisher
Sun Y, Lu F, Yu X, Wang B, Chen J, Lu F, et al. Exogenous H2S Promoted USP8 Sulfhydration to Regulate Mitophagy in the Hearts of db/db Mice. Aging Dis. 2020;11:269-285 pubmed publisher
Wang W, Hu X, Xia Z, Liu Z, Zhong Z, Lu Z, et al. Mild Hypothermia Attenuates Hepatic Ischemia-Reperfusion Injury through Regulating the JAK2/STAT3-CPT1a-Dependent Fatty Acid β-Oxidation. Oxid Med Cell Longev. 2020;2020:5849794 pubmed publisher
Luo J, Yang C, Luo X, Yang Y, Li J, Song B, et al. Chlorogenic acid attenuates cyclophosphamide-induced rat interstitial cystitis. Life Sci. 2020;254:117590 pubmed publisher
Cui G, Li L, Xu W, Wang M, Jiao D, Yao B, et al. Astaxanthin Protects Ochratoxin A-Induced Oxidative Stress and Apoptosis in the Heart via the Nrf2 Pathway. Oxid Med Cell Longev. 2020;2020:7639109 pubmed publisher
Luan Y, Cui K, Tang Z, Ruan Y, Liu K, Wang T, et al. Human Tissue Kallikrein 1 Improves Erectile Dysfunction of Streptozotocin-Induced Diabetic Rats by Inhibition of Excessive Oxidative Stress and Activation of the PI3K/AKT/eNOS Pathway. Oxid Med Cell Longev. 2020;2020:6834236 pubmed publisher
Jin W, Xue Y, Xue Y, Han X, Song Q, Zhang J, et al. Tannic acid ameliorates arsenic trioxide-induced nephrotoxicity, contribution of NF-κB and Nrf2 pathways. Biomed Pharmacother. 2020;126:110047 pubmed publisher
Xiong Y, Yin Q, Li J, He S. Oxidative Stress and Endoplasmic Reticulum Stress Are Involved in the Protective Effect of Alpha Lipoic Acid Against Heat Damage in Chicken Testes. Animals (Basel). 2020;10: pubmed publisher
Liu H, Zhang W, Fang Y, Yang H, Tian L, Li K, et al. Neurotoxicity of aluminum oxide nanoparticles and their mechanistic role in dopaminergic neuron injury involving p53-related pathways. J Hazard Mater. 2020;392:122312 pubmed publisher
Wang P, Zhao M, Chen Z, Wu G, Fujino M, Zhang C, et al. Hydrogen Gas Attenuates Hypoxic-Ischemic Brain Injury via Regulation of the MAPK/HO-1/PGC-1a Pathway in Neonatal Rats. Oxid Med Cell Longev. 2020;2020:6978784 pubmed publisher
Xu B, Zang S, Lang L, Lian S, Lu J, Li S, et al. Down-regulation of miR-383-5p suppresses apoptosis in oxidative stress rat hepatocytes by targeting Bcl2. J Anim Physiol Anim Nutr (Berl). 2020;: pubmed publisher
Chen G, Zhang X, Chen H, Lin H, Wu H, Lin H, et al. miR-22 represses osteoblast viability with ESR1 presenting a direct target and indirectly inactivating p38 MAPK/JNK signaling. J Gene Med. 2020;22:e3174 pubmed publisher
Shang Y, Wang Q, Li J, Zhao Q, Huang X, Dong H, et al. The Acetone Indigo Red Dehydrating Agent IF203 Induces HepG2 Cell Death Through Cell Cycle Arrest, Autophagy and Apoptosis. Onco Targets Ther. 2020;13:473-486 pubmed publisher
Shopit A, Niu M, Wang H, Tang Z, Li X, Tesfaldet T, et al. Protection of diabetes-induced kidney injury by phosphocreatine via the regulation of ERK/Nrf2/HO-1 signaling pathway. Life Sci. 2020;242:117248 pubmed publisher
Ying C, Ying L, Yanxia L, Le W, Lili C. High mobility group box 1 antibody represses autophagy and alleviates hippocampus damage in pilocarpine-induced mouse epilepsy model. Acta Histochem. 2020;122:151485 pubmed publisher
Pei G, Xu L, Huang W, Yin J. The protective role of microRNA-133b in restricting hippocampal neurons apoptosis and inflammatory injury in rats with depression by suppressing CTGF. Int Immunopharmacol. 2020;78:106076 pubmed publisher
Liu Q, Zhang S, Zhu D, Tang X, Che Y, Feng X. The parthenolide derivative ACT001 synergizes with low doses of L-DOPA to improve MPTP-induced Parkinson's disease in mice. Behav Brain Res. 2020;379:112337 pubmed publisher
Jin W, Zhang Y, Xue Y, Han X, Zhang X, Ma Z, et al. Crocin attenuates isoprenaline-induced myocardial fibrosis by targeting TLR4/NF-κB signaling: connecting oxidative stress, inflammation, and apoptosis. Naunyn Schmiedebergs Arch Pharmacol. 2020;393:13-23 pubmed publisher
Guo J, Fu W, Xiang M, Zhang Y, Zhou K, Xu C, et al. Notch1 Drives the Formation and Proliferation of Intrahepatic Cholangiocarcinoma. Curr Med Sci. 2019;39:929-937 pubmed publisher
Li Y, Chen H, Yang Y, Niu M, Wang J, Wu Y, et al. Danshen formula granule and salvianic acid A alleviate ethanol-induced neurotoxicity. J Nat Med. 2019;: pubmed publisher
Du Y, Qian B, Gao L, Tan P, Chen H, Wang A, et al. Aloin Preconditioning Attenuates Hepatic Ischemia/Reperfusion Injury via Inhibiting TLR4/MyD88/NF-κB Signal Pathway In Vivo and In Vitro. Oxid Med Cell Longev. 2019;2019:3765898 pubmed publisher
Guo X, Zhang Y, Lu C, Qu F, Jiang X. Protective effect of hyperoside on heart failure rats via attenuating myocardial apoptosis and inducing autophagy. Biosci Biotechnol Biochem. 2019;:1-11 pubmed publisher
Yang L, Jiang L, Jiang D, Liu B, Jin S. The protective effects of salvianolic acid A against hepatic ischemia-reperfusion injury via inhibiting expression of toll-like receptor 4 in rats. Arch Med Sci. 2019;15:1599-1607 pubmed publisher
Xu W, Zheng H, Yang R, Liu T, Yu W, Zheng X, et al. Mitochondrial NDUFA4L2 attenuates the apoptosis of nucleus pulposus cells induced by oxidative stress via the inhibition of mitophagy. Exp Mol Med. 2019;51:140 pubmed publisher
Liu W, Zhou Y, Liang R, Zhang Y. Inhibition of cyclin-dependent kinase 5 activity alleviates diabetes-related cognitive deficits. FASEB J. 2019;33:14506-14515 pubmed publisher
Song S, Chu L, Liang H, Chen J, Liang J, Huang Z, et al. Protective Effects of Dioscin Against Doxorubicin-Induced Hepatotoxicity Via Regulation of Sirt1/FOXO1/NF-κb Signal. Front Pharmacol. 2019;10:1030 pubmed publisher
Feng X, Xiong W, Yuan M, Zhan J, Zhu X, Wei Z, et al. Down-regulated microRNA-183 mediates the Jak/Stat signaling pathway to attenuate hippocampal neuron injury in epilepsy rats by targeting Foxp1. Cell Cycle. 2019;18:3206-3222 pubmed publisher
Zeng Z, Liu Y, Zheng W, Liu L, Yin H, Zhang S, et al. MicroRNA-129-5p alleviates nerve injury and inflammatory response of Alzheimer's disease via downregulating SOX6. Cell Cycle. 2019;18:3095-3110 pubmed publisher
He F, Dai R, Zhou X, Li X, Song X, Yan H, et al. Protective effect of 4-Methoxy benzyl alcohol on the neurovascular unit after cerebral ischemia reperfusion injury. Biomed Pharmacother. 2019;118:109260 pubmed publisher
Wu X, Kong Q, Zhan L, Qiu Z, Huang Q, Song X. TIPE2 ameliorates lipopolysaccharide-induced apoptosis and inflammation in acute lung injury. Inflamm Res. 2019;68:981-992 pubmed publisher
Feng C, Li D, Chen M, Jiang L, Liu X, Li Q, et al. Citreoviridin induces myocardial apoptosis through PPAR-γ-mTORC2-mediated autophagic pathway and the protective effect of thiamine and selenium. Chem Biol Interact. 2019;311:108795 pubmed publisher
Liu Y, Chen H, Zhang L, Zhang T, Ren X. The Association Between Thyroid Injury and Apoptosis, and Alterations of Bax, Bcl-2, and Caspase-3 mRNA/Protein Expression Induced by Nickel Sulfate in Wistar Rats. Biol Trace Elem Res. 2019;: pubmed publisher
Yang Q, Zhu J, Luo X, Li F, Cong L, Wang Y, et al. Melatonin attenuates cadmium-induced ovulatory dysfunction by suppressing endoplasmic reticulum stress and cell apoptosis. Reprod Biol Endocrinol. 2019;17:61 pubmed publisher
Cheng Y, Li J, Wang C, Yang H, Wang Y, Zhan T, et al. Inhibition of long non-coding RNA Malat1 attenuates high glucose-induced cardiomyocyte apoptosis via regulation of miR-181a-5p. Exp Anim. 2019;: pubmed publisher
Wang Y, Wu J, Li Y, Qi X. Polysaccharides of Fructus corni Improve Ovarian Function in Mice with Aging-Associated Perimenopause Symptoms. Evid Based Complement Alternat Med. 2019;2019:2089586 pubmed publisher
Huang X, Qiao F, Xue P. The protective role of microRNA-140-5p in synovial injury of rats with knee osteoarthritis via inactivating the TLR4/Myd88/NF-κB signaling pathway. Cell Cycle. 2019;18:2344-2358 pubmed publisher
Zhang H, Chen F, He S, Liang Y, Wang Z, Wang L, et al. In vivo tracking on longer retention of transplanted myocardin gene-modified adipose-derived stem cells to improve erectile dysfunction in diabetic rats. Stem Cell Res Ther. 2019;10:208 pubmed publisher
Xu W, Yang R, Zheng H, Yu W, Zheng X, Li B, et al. PGC-1α acts as an mediator of Sirtuin2 to protect annulus fibrosus from apoptosis induced by oxidative stress through restraining mitophagy. Int J Biol Macromol. 2019;136:1007-1017 pubmed publisher
Xu Y, Yao S, Gao D, Li W, Zheng D, Zhang Q. Effect of astaxanthin on apoptosis of rat renal tubular epithelial cells induced by iohexol. Am J Transl Res. 2019;11:3039-3047 pubmed
Zhou L, Wang S, Cao L, Ren X, Li Y, Shao J, et al. Lead acetate induces apoptosis in Leydig cells by activating PPARγ/caspase-3/PARP pathway. Int J Environ Health Res. 2019;:1-11 pubmed publisher
Zhang Y, Chi X, Wang Z, Bi S, Wang Y, Shi F, et al. Protective effects of Panax notoginseng saponins on PME-Induced nephrotoxicity in mice. Biomed Pharmacother. 2019;116:108970 pubmed publisher
Sun X, Huang X, Zhu X, Liu L, Mo S, Wang H, et al. HBOA ameliorates CCl4-incuded liver fibrosis through inhibiting TGF-β1/Smads, NF-κB and ERK signaling pathways. Biomed Pharmacother. 2019;115:108901 pubmed publisher
Zhang J, Yao D, Zhang J, Song Y, Mo F, Chu X, et al. TGF-β mediates thoracic radiation-induced abscopal effects of testis injury in rat. Biochem Biophys Res Commun. 2019;: pubmed publisher
Luo T, Zeng X, Yang W, Zhang Y. Treatment with metformin prevents myocardial ischemia-reperfusion injury via STEAP4 signaling pathway. Anatol J Cardiol. 2019;21:261-271 pubmed publisher
Chen C, Jiang L, Zhang M, Pan X, Peng C, Huang W, et al. Isodunnianol alleviates doxorubicin-induced myocardial injury by activating protective autophagy. Food Funct. 2019;10:2651-2657 pubmed publisher
Dong S, Ji J, Hu L, Wang H. Dihydromyricetin alleviates acetaminophen-induced liver injury via the regulation of transformation, lipid homeostasis, cell death and regeneration. Life Sci. 2019;227:20-29 pubmed publisher
Yin F, Yan J, Zhao Y, Guo K, Zhang Z, Li A, et al. Bone marrow mesenchymal stem cells repair Cr (VI)- injured kidney by regulating mitochondria-mediated apoptosis and mitophagy mediated via the MAPK signaling pathway. Ecotoxicol Environ Saf. 2019;176:234-241 pubmed publisher
Zhang L, Liu Y, Huang Z, Nan L, Wang F, Zhou S, et al. Toxicity Effects of Methylene Blue on Rat Intervertebral Disc Annulus Fibrosus Cells. Pain Physician. 2019;22:155-164 pubmed
Huang Z, Zheng Y, Li N, Cai S, Huang Y, Wang J, et al. Protective effects of specific cannabinoid receptor 2 agonist GW405833 on concanavalin A-induced acute liver injury in mice. Acta Pharmacol Sin. 2019;: pubmed publisher
Zhang Y, Gao J, Sun W, Wen X, Xi Y, Wang Y, et al. H2S restores the cardioprotective effects of ischemic post-conditioning by upregulating HB-EGF/EGFR signaling. Aging (Albany NY). 2019;11:1745-1758 pubmed publisher
Hu H, Wang C, Jin Y, Meng Q, Liu Q, Liu Z, et al. Catalpol Inhibits Homocysteine-induced Oxidation and Inflammation via Inhibiting Nox4/NF-κB and GRP78/PERK Pathways in Human Aorta Endothelial Cells. Inflammation. 2019;42:64-80 pubmed publisher
Deng J, Feng J, Liu T, Lu X, Wang W, Liu N, et al. Beraprost sodium preconditioning prevents inflammation, apoptosis, and autophagy during hepatic ischemia-reperfusion injury in mice via the P38 and JNK pathways. Drug Des Devel Ther. 2018;12:4067-4082 pubmed publisher
Zhao Y, Zhang H, Yang X, Zhang Y, Feng S, Yu F, et al. Fine Particulate Matter-Induced Exacerbation of Allergic Asthma via Activation of T-cell Immunoglobulin and Mucin Domain 1. Chin Med J (Engl). 2018;131:2461-2473 pubmed publisher
Zhao W, Che C, Liu K, Zhang J, Jiang N, Yuan K, et al. Fenretinide Inhibits Neutrophil Recruitment and IL-1β Production in Aspergillus fumigatus Keratitis. Cornea. 2018;37:1579-1585 pubmed publisher
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Zhang Y, Yang B, Zhao J, Li X, Zhang L, Zhai Z. Proteasome Inhibitor Carbobenzoxy-L-Leucyl-L-Leucyl-L-Leucinal (MG132) Enhances Therapeutic Effect of Paclitaxel on Breast Cancer by Inhibiting Nuclear Factor (NF)-κB Signaling. Med Sci Monit. 2018;24:294-304 pubmed
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Chen Y, Li Y, Xu H, Li G, Ma Y, Pang Y. MORIN MITIGATES OXIDATIVE STRESS, APOPTOSIS AND INFLAMMATION IN CEREBRAL ISCHEMIC RATS. Afr J Tradit Complement Altern Med. 2017;14:348-355 pubmed publisher
Zhao S, Li L, Wang S, Yu C, Xiao B, Lin L, et al. H2O2 treatment or serum deprivation induces autophagy and apoptosis in naked mole-rat skin fibroblasts by inhibiting the PI3K/Akt signaling pathway. Oncotarget. 2016;7:84839-84850 pubmed publisher
product information
CatalogNo :
26593-1-AP
AntigenName :
Bcl2
Package :
150UL
Price :
299 USD
Exsists20ul :
20ul trial size available
FullName :
B-cell leukemia/lymphoma 2
Immunogen :
Fusion Protein
Species :
chicken, human, mouse, rat
Host :
Rabbit
IsConjugated :
Unconjugated
AntigenSpecies :
mouse
Application :
WB, IHC, IF, ELISA
Clonlity :
Polyclonal
IsoType :
IgG
Synonyms :
AW986256, B cell leukemia/lymphoma 2, Bcl2, Bcl-2, C430015F12Rik, D630044D05Rik, D830018M01Rik
PrimaryOrSecondary :
Primary
AntibodyBuffer :
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
GenBankNo :
NM-009741
PurifyMethod :
Antigen affinity purification
NewAb :
False
IsSellable :
True
Feature :
siRNA
AppTiter :
IF 1:100 ; IHC 1:400 ; WB 1:1500 ;
company information
Proteintech Group
2201 W. Campbell Park Dr. STE12
Chicago, IL 60612
Proteintech@ptglab.com
https://www.ptglab.com
1-312-455-8498
headquarters: USA
At Proteintech, we produce every single antibody we sell; we do not rely on or supply to any other antibody providers: our products are unique and we are 100% accountable for each one. We realize this accountability by validating in-house, providing extensive technical support and guaranteeing your success: in addition to helping you troubleshoot your experiment, we will offer you a full cash refund if you are in any way dissatisfied. We can guarantee satisfaction because we have confidence in our products, confidence cultivated by the science behind our antibodies: we make them using as much of the native protein as possible, and purifying them using affinity purification with the original antigen. We carry out antibody production over a 102-day period, which allows for better antigen fitting to MHC molecules and affinity maturation in the host. This approach results in higher affinity antibodies with greater sensitivity, which you can use in any application and in multiple species.
You can only buy Proteintech antibodies directly from Proteintech or via one of its approved distributors — when you receive your antibody and see the Proteintech logo on the vial, know that you hold something that is truly unique.