This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Proteintech Group
product type :
antibody
product name :
BDNF
catalog :
25699-1-AP
quantity :
150 ul
price :
279 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry
citations: 19
Reference
Belviranli M, Okudan N. Exercise Training Protects Against Aging-Induced Cognitive Dysfunction via Activation of the Hippocampal PGC-1?/FNDC5/BDNF Pathway. Neuromolecular Med. 2018;20:386-400 pubmed publisher
Chen W, Liang T, Zuo W, Wu X, Shen Z, Wang F, et al. Neuroprotective effect of 1-Deoxynojirimycin on cognitive impairment, ?-amyloid deposition, and neuroinflammation in the SAMP8 mice. Biomed Pharmacother. 2018;106:92-97 pubmed publisher
Wei Y, Fang C, Liu S, Yang W, Wei L, Lei X, et al. Long-term moderate exercise enhances specific proteins that constitute neurotrophin signaling pathway: A TMT-based quantitative proteomic analysis of rat plasma. J Proteomics. 2018;185:39-50 pubmed publisher
Lu Y, Ho C, McIntyre R, Wang W, Ho R. Effects of vortioxetine and fluoxetine on the level of Brain Derived Neurotrophic Factors (BDNF) in the hippocampus of chronic unpredictable mild stress-induced depressive rats. Brain Res Bull. 2018;142:1-7 pubmed publisher
Nam S, Cho I, Seo J, Go T, Kim J, Nahm S, et al. Ascorbic Acid Attenuates Lead-Induced Alterations in the Synapses in the Developing Rat Cerebellum. Biol Trace Elem Res. 2018;: pubmed publisher
Nagahara A, Wilson B, Ivasyk I, Kovacs I, Rawalji S, Bringas J, et al. MR-guided delivery of AAV2-BDNF into the entorhinal cortex of non-human primates. Gene Ther. 2018;25:104-114 pubmed publisher
Zhu B, Zhao L, Luo D, Xu D, Tan T, Dong Z, et al. Furin promotes dendritic morphogenesis and learning and memory in transgenic mice. Cell Mol Life Sci. 2018;75:2473-2488 pubmed publisher
Gu X, Fu C, Lin L, Liu S, Su X, Li A, et al. miR-124 and miR-9 mediated downregulation of HDAC5 promotes neurite development through activating MEF2C-GPM6A pathway. J Cell Physiol. 2018;233:673-687 pubmed publisher
Sheng C, Xu P, Zhou K, Deng D, Zhang C, Wang Z. Icariin Attenuates Synaptic and Cognitive Deficits in an A?1-42-Induced Rat Model of Alzheimer's Disease. Biomed Res Int. 2017;2017:7464872 pubmed publisher
Dong D, Mao Y, Huang C, Jiao Q, Pan H, Ma L, et al. Astrocytes mediated the nootropic and neurotrophic effects of Sarsasapogenin-AA13 via upregulating brain-derived neurotrophic factor. Am J Transl Res. 2017;9:4015-4025 pubmed
WenBo W, Fei Z, YiHeng D, Wei W, TingMang Y, WenHao Z, et al. Human Umbilical Cord Mesenchymal Stem Cells Overexpressing Nerve Growth Factor Ameliorate Diabetic Cystopathy in Rats. Neurochem Res. 2017;42:3537-3547 pubmed publisher
Zhang X, Zheng W, Wang T, Ren P, Wang F, Ma X, et al. Danshen-Chuanxiong-Honghua Ameliorates Cerebral Impairment and Improves Spatial Cognitive Deficits after Transient Focal Ischemia and Identification of Active Compounds. Front Pharmacol. 2017;8:452 pubmed publisher
Cui M, Xiao H, Li Y, Dong J, Luo D, Li H, et al. Total abdominal irradiation exposure impairs cognitive function involving miR-34a-5p/BDNF axis. Biochim Biophys Acta. 2017;1863:2333-2341 pubmed publisher
Shiromoto T, Okabe N, Lu F, Maruyama Nakamura E, Himi N, Narita K, et al. The Role of Endogenous Neurogenesis in Functional Recovery and Motor Map Reorganization Induced by Rehabilitative Therapy after Stroke in Rats. J Stroke Cerebrovasc Dis. 2017;26:260-272 pubmed publisher
Brock J, Graham L, Staufenberg E, Collyer E, Koffler J, Tuszynski M. Bone Marrow Stromal Cell Intraspinal Transplants Fail to Improve Motor Outcomes in a Severe Model of Spinal Cord Injury. J Neurotrauma. 2016;33:1103-14 pubmed publisher
Yang L, Jiang F, Wu G, Deng K, Wen M, Zhou X, et al. Acute Treatment with a Novel TRPC4/C5 Channel Inhibitor Produces Antidepressant and Anxiolytic-Like Effects in Mice. PLoS ONE. 2015;10:e0136255 pubmed publisher
Hong Z, Yu S, Wang Z, Zhu Y. SCM-198 Ameliorates Cognitive Deficits, Promotes Neuronal Survival and Enhances CREB/BDNF/TrkB Signaling without Affecting Aβ Burden in AβPP/PS1 Mice. Int J Mol Sci. 2015;16:18544-63 pubmed publisher
Wang N, Zhang Y, Wu L, Wang Y, Cao Y, He L, et al. Puerarin protected the brain from cerebral ischemia injury via astrocyte apoptosis inhibition. Neuropharmacology. 2014;79:282-9 pubmed publisher
Nagahara A, Mateling M, Kovacs I, Wang L, Eggert S, Rockenstein E, et al. Early BDNF treatment ameliorates cell loss in the entorhinal cortex of APP transgenic mice. J Neurosci. 2013;33:15596-602 pubmed publisher
product information
Catalog Number :
25699-1-AP
Item Name :
BDNF
Quantity / Package Size :
150 ul
Price :
279 USD
20ul trial size available :
20ul trial size available
FullName :
brain-derived neurotrophic factor
Antigen :
Fusion Protein
Species Reactivity :
cynomologus macaques, human, mouse, rat
Host Species :
Rabbit
Conjugate :
Unconjugated
Antigen Species :
human
Applications :
WB, IHC, IF, ELISA
Type :
Polyclonal
Isotype :
IgG
Antigen Synonyms :
Abrineurin, BDNF
Primary or Secondary? :
Primary
AntibodyBuffer :
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
GenBankNo :
BC029795
Category :
Apoptosis;Binding Proteins;Cytoskeleton/Scaffold Proteins;Development;Growth Factor/Cytokine/Hormone;Membrane Proteins;Neurology;Signal transduction;
Form/Purification :
Antigen affinity purification
IsSellable :
1
Feature :
siRNA
AppTiter :
IF 1:50 ; IHC 1:200 ; WB 1:300 ;
company information
Proteintech Group
2201 W. Campbell Park Dr. STE12
Chicago, IL 60612
Proteintech@ptglab.com
www.ptglab.com
1-312-455-8498
headquarters: USA
At Proteintech, we produce every single antibody we sell; we do not rely on or supply to any other antibody providers: our products are unique and we are 100% accountable for each one. We realize this accountability by validating in-house, providing extensive technical support and guaranteeing your success: in addition to helping you troubleshoot your experiment, we will offer you a full cash refund if you are in any way dissatisfied. We can guarantee satisfaction because we have confidence in our products, confidence cultivated by the science behind our antibodies: we make them using as much of the native protein as possible, and purifying them using affinity purification with the original antigen. We carry out antibody production over a 102-day period, which allows for better antigen fitting to MHC molecules and affinity maturation in the host. This approach results in higher affinity antibodies with greater sensitivity, which you can use in any application and in multiple species.
You can only buy Proteintech antibodies directly from Proteintech or via one of its approved distributors — when you receive your antibody and see the Proteintech logo on the vial, know that you hold something that is truly unique.