This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Proteintech Group
product type :
antibody
product name :
CHCHD3
catalog :
25625-1-AP
quantity :
150UL
price :
299 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation
citations: 13
Published Application/Species/Sample/DilutionReference
  • western blot; human; fig 6a
Straub I, Janer A, Weraarpachai W, Zinman L, Robertson J, Rogaeva E, et al. Loss of CHCHD10-CHCHD2 complexes required for respiration underlies the pathogenicity of a CHCHD10 mutation in ALS. Hum Mol Genet. 2018;27:178-189 pubmed publisher
Monsálves Álvarez M, Morales P, Castro Sepúlveda M, Sepúlveda C, Rodriguez J, Chiong M, et al. β-Hydroxybutyrate Increases Exercise Capacity Associated with Changes in Mitochondrial Function in Skeletal Muscle. Nutrients. 2020;12: pubmed publisher
Liu T, Woo J, Bukhari M, LePochat P, Chacko A, Selenica M, et al. CHCHD10-regulated OPA1-mitofilin complex mediates TDP-43-induced mitochondrial phenotypes associated with frontotemporal dementia. FASEB J. 2020;34:8493-8509 pubmed publisher
Kondadi A, Anand R, Hänsch S, Urbach J, Zobel T, Wolf D, et al. Cristae undergo continuous cycles of membrane remodelling in a MICOS-dependent manner. EMBO Rep. 2020;21:e49776 pubmed publisher
Violitzi F, Perivolidi V, Thireou T, Grivas I, Haralambous S, Samiotaki M, et al. Mapping Interactome Networks of DNAJC11, a Novel Mitochondrial Protein Causing Neuromuscular Pathology in Mice. J Proteome Res. 2019;18:3896-3912 pubmed publisher
Zhao Y, Sun X, Hu D, Prosdocimo D, Hoppel C, Jain M, et al. ATAD3A oligomerization causes neurodegeneration by coupling mitochondrial fragmentation and bioenergetics defects. Nat Commun. 2019;10:1371 pubmed publisher
Hu D, Sun X, Liao X, Zhang X, Zarabi S, Schimmer A, et al. Alpha-synuclein suppresses mitochondrial protease ClpP to trigger mitochondrial oxidative damage and neurotoxicity. Acta Neuropathol. 2019;137:939-960 pubmed publisher
Gautam M, Jara J, Kocak N, Rylaarsdam L, Kim K, Bigio E, et al. Mitochondria, ER, and nuclear membrane defects reveal early mechanisms for upper motor neuron vulnerability with respect to TDP-43 pathology. Acta Neuropathol. 2019;137:47-69 pubmed publisher
Serricchio M, Vissa A, Kim P, Yip C, McQuibban G. Cardiolipin synthesizing enzymes form a complex that interacts with cardiolipin-dependent membrane organizing proteins. Biochim Biophys Acta Mol Cell Biol Lipids. 2018;1863:447-457 pubmed publisher
Vukotic M, Nolte H, König T, Saita S, Ananjew M, Kruger M, et al. Acylglycerol Kinase Mutated in Sengers Syndrome Is a Subunit of the TIM22 Protein Translocase in Mitochondria. Mol Cell. 2017;67:471-483.e7 pubmed publisher
Glytsou C, Calvo E, Cogliati S, Mehrotra A, Anastasia I, Rigoni G, et al. Optic Atrophy 1 Is Epistatic to the Core MICOS Component MIC60 in Mitochondrial Cristae Shape Control. Cell Rep. 2016;17:3024-3034 pubmed publisher
Plecitá Hlavatá L, Engstová H, Alán L, Špaček T, Dlasková A, Smolková K, et al. Hypoxic HepG2 cell adaptation decreases ATP synthase dimers and ATP production in inflated cristae by mitofilin down-regulation concomitant to MICOS clustering. FASEB J. 2016;30:1941-57 pubmed publisher
Ding C, Wu Z, Huang L, Wang Y, Xue J, Chen S, et al. Mitofilin and CHCHD6 physically interact with Sam50 to sustain cristae structure. Sci Rep. 2015;5:16064 pubmed publisher
product information
CatalogNo :
25625-1-AP
AntigenName :
CHCHD3
Package :
150UL
Price :
299 USD
Exsists20ul :
20ul trial size available
FullName :
coiled-coil-helix-coiled-coil-helix domain containing 3
Immunogen :
Fusion Protein
Species :
human, mouse
Host :
Rabbit
IsConjugated :
Unconjugated
AntigenSpecies :
human
Application :
WB, IP, IHC, IF, ELISA
Clonlity :
Polyclonal
IsoType :
IgG
Synonyms :
CHCHD3, MIC19, MINOS3
PrimaryOrSecondary :
Primary
AntibodyBuffer :
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
GenBankNo :
BC014839
Category :
Binding Proteins;Cytoskeleton/Scaffold Proteins;
PurifyMethod :
Antigen affinity purification
NewAb :
False
IsSellable :
True
AppTiter :
IF 1:50 ; IHC 1:200 ; IP 1:1000 ; WB 1:8000 ;
company information
Proteintech Group
2201 W. Campbell Park Dr. STE12
Chicago, IL 60612
Proteintech@ptglab.com
https://www.ptglab.com
1-312-455-8498
headquarters: USA
At Proteintech, we produce every single antibody we sell; we do not rely on or supply to any other antibody providers: our products are unique and we are 100% accountable for each one. We realize this accountability by validating in-house, providing extensive technical support and guaranteeing your success: in addition to helping you troubleshoot your experiment, we will offer you a full cash refund if you are in any way dissatisfied. We can guarantee satisfaction because we have confidence in our products, confidence cultivated by the science behind our antibodies: we make them using as much of the native protein as possible, and purifying them using affinity purification with the original antigen. We carry out antibody production over a 102-day period, which allows for better antigen fitting to MHC molecules and affinity maturation in the host. This approach results in higher affinity antibodies with greater sensitivity, which you can use in any application and in multiple species.
You can only buy Proteintech antibodies directly from Proteintech or via one of its approved distributors — when you receive your antibody and see the Proteintech logo on the vial, know that you hold something that is truly unique.