This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Proteintech Group
product type :
antibody
product name :
ZCCHC6
catalog :
25196-1-AP
quantity :
150UL
price :
299 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, ELISA, immunoprecipitation
citations: 7
Reference
Takahashi K, Jeong D, Wang S, Narita M, Jin X, Iwasaki M, et al. Critical Roles of Translation Initiation and RNA Uridylation in Endogenous Retroviral Expression and Neural Differentiation in Pluripotent Stem Cells. Cell Rep. 2020;31:107715 pubmed publisher
Yang A, Shao T, Bofill De Ros X, Lian C, Villanueva P, Dai L, et al. AGO-bound mature miRNAs are oligouridylated by TUTs and subsequently degraded by DIS3L2. Nat Commun. 2020;11:2765 pubmed publisher
Kim H, Kim J, Yu S, Lee Y, Park J, Choi R, et al. A Mechanism for microRNA Arm Switching Regulated by Uridylation. Mol Cell. 2020;78:1224-1236.e5 pubmed publisher
Yang A, Bofill De Ros X, Shao T, Jiang M, Li K, Villanueva P, et al. 3' Uridylation Confers miRNAs with Non-canonical Target Repertoires. Mol Cell. 2019;: pubmed publisher
Kozlowski E, Wasserman G, Morgan M, O Carroll D, Ramirez N, Gummuluru S, et al. The RNA uridyltransferase Zcchc6 is expressed in macrophages and impacts innate immune responses. PLoS ONE. 2017;12:e0179797 pubmed publisher
Gutiérrez Vázquez C, Enright A, Rodríguez Galán A, Pérez García A, Collier P, Jones M, et al. 3' Uridylation controls mature microRNA turnover during CD4 T-cell activation. RNA. 2017;23:882-891 pubmed publisher
Lackey P, Welch J, Marzluff W. TUT7 catalyzes the uridylation of the 3' end for rapid degradation of histone mRNA. RNA. 2016;22:1673-1688 pubmed
product information
CatalogNo :
25196-1-AP
AntigenName :
ZCCHC6
Package :
150UL
Price :
299 USD
Exsists20ul :
20ul trial size available
FullName :
zinc finger, CCHC domain containing 6
Immunogen :
Fusion Protein
Species :
human, mouse, rat
Host :
Rabbit
IsConjugated :
Unconjugated
AntigenSpecies :
human
Application :
WB, IP, CoIP, ELISA
Clonlity :
Polyclonal
IsoType :
IgG
Synonyms :
HS2, KIAA1711, PAPD6, Terminal uridylyltransferase 7, TUT7, TUTase 7, ZCCHC6
PrimaryOrSecondary :
Primary
AntibodyBuffer :
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
GenBankNo :
BC032456
Category :
Binding Proteins;
PurifyMethod :
Antigen affinity purification
NewAb :
False
IsSellable :
True
Feature :
siRNA
AppTiter :
IP 1:1000 ; WB 1:1000 ;
company information
Proteintech Group
2201 W. Campbell Park Dr. STE12
Chicago, IL 60612
Proteintech@ptglab.com
https://www.ptglab.com
1-312-455-8498
headquarters: USA
At Proteintech, we produce every single antibody we sell; we do not rely on or supply to any other antibody providers: our products are unique and we are 100% accountable for each one. We realize this accountability by validating in-house, providing extensive technical support and guaranteeing your success: in addition to helping you troubleshoot your experiment, we will offer you a full cash refund if you are in any way dissatisfied. We can guarantee satisfaction because we have confidence in our products, confidence cultivated by the science behind our antibodies: we make them using as much of the native protein as possible, and purifying them using affinity purification with the original antigen. We carry out antibody production over a 102-day period, which allows for better antigen fitting to MHC molecules and affinity maturation in the host. This approach results in higher affinity antibodies with greater sensitivity, which you can use in any application and in multiple species.
You can only buy Proteintech antibodies directly from Proteintech or via one of its approved distributors — when you receive your antibody and see the Proteintech logo on the vial, know that you hold something that is truly unique.