DNMT1 | Proteintech Group 24206-1-AP product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Proteintech Group

product type :

antibody

product name :

DNMT1

catalog :

24206-1-AP

quantity :

150UL

price :

299 USD

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot, ELISA, immunocytochemistry, immunoprecipitation

citations: 27

Reference
Li K, Ning T, Wang H, Jiang Y, Zhang J, Ge Z. Nanosecond pulsed electric fields enhance mesenchymal stem cells differentiation via DNMT1-regulated OCT4/NANOG gene expression. Stem Cell Res Ther. 2020;11:308 pubmed publisher
Guo J, Zhou S, Huang P, Xu S, Zhang G, He H, et al. NNK-mediated upregulation of DEPDC1 stimulates the progression of oral squamous cell carcinoma by inhibiting CYP27B1 expression. Am J Cancer Res. 2020;10:1745-1760 pubmed
Omer N, Hu Y, Idriss A, Abobaker H, Hou Z, Yang S, et al. Dietary betaine improves egg-laying rate in hens through hypomethylation and glucocorticoid receptor-mediated activation of hepatic lipogenesis-related genes. Poult Sci. 2020;99:3121-3132 pubmed publisher
Hu Y, Feng Y, Ding Z, Lv L, Sui Y, Sun Q, et al. Maternal betaine supplementation decreases hepatic cholesterol deposition in chicken offspring with epigenetic modulation of SREBP2 and CYP7A1 genes. Poult Sci. 2020;99:3111-3120 pubmed publisher
Kong R, Sun G, Li X, Wu L, Li L, Li Y, et al. Small Molecule Inhibitor C188-9 Synergistically Enhances the Demethylated Activity of Low-Dose 5-Aza-2'-Deoxycytidine Against Pancreatic Cancer. Front Oncol. 2020;10:612 pubmed publisher
Wu C, Guo E, Ming J, Sun W, Nie X, Sun L, et al. Radiation-Induced DNMT3B Promotes Radioresistance in Nasopharyngeal Carcinoma through Methylation of p53 and p21. Mol Ther Oncolytics. 2020;17:306-319 pubmed publisher
Meng F, Liu X, Lin C, Xu L, Liu J, Zhang P, et al. SMYD2 suppresses APC2 expression to activate the Wnt/β-catenin pathway and promotes epithelial-mesenchymal transition in colorectal cancer. Am J Cancer Res. 2020;10:997-1011 pubmed
Chen D, Feng X, Lv Z, Xu X, Lu Y, Wu W, et al. ACADS acts as a potential methylation biomarker associated with the proliferation and metastasis of hepatocellular carcinomas. Aging (Albany NY). 2019;11:8825-8844 pubmed publisher
Zhu X, Du J, Yu J, Guo R, Feng Y, Qiao L, et al. LncRNA NKILA regulates endothelium inflammation by controlling a NF-κB/KLF4 positive feedback loop. J Mol Cell Cardiol. 2019;126:60-69 pubmed publisher
Jia L, Zeng Y, Hu Y, Liu J, Yin C, Niu Y, et al. Homocysteine impairs porcine oocyte quality via deregulation of one-carbon metabolism and hypermethylation of mitochondrial DNA†. Biol Reprod. 2019;100:907-916 pubmed publisher
Hu Y, Sun Q, Hu Y, Hou Z, Zong Y, Omer N, et al. Corticosterone-Induced Lipogenesis Activation and Lipophagy Inhibition in Chicken Liver Are Alleviated by Maternal Betaine Supplementation. J Nutr. 2018;148:316-325 pubmed publisher
Li Y, Li L, Qian Z, Lin B, Chen J, Luo Y, et al. Phosphatidylinositol 3-Kinase-DNA Methyltransferase 1-miR-1281-Histone Deacetylase 4 Regulatory Axis Mediates Platelet-Derived Growth Factor-Induced Proliferation and Migration of Pulmonary Artery Smooth Muscle Cells. J Am Heart Assoc. 2018;7: pubmed publisher
Hou Z, Sun Q, Hu Y, Yang S, Zong Y, Zhao R. Maternal betaine administration modulates hepatic type 1 iodothyronine deiodinase (Dio1) expression in chicken offspring through epigenetic modifications. Comp Biochem Physiol B Biochem Mol Biol. 2018;218:30-36 pubmed publisher
Yang S, Zhao N, Yang Y, Hu Y, Dong H, Zhao R. Mitotically Stable Modification of DNA Methylation in IGF2/H19 Imprinting Control Region Is Associated with Activated Hepatic IGF2 Expression in Offspring Rats from Betaine-Supplemented Dams. J Agric Food Chem. 2018;66:2704-2713 pubmed publisher
Omer N, Hu Y, Hu Y, Idriss A, Abobaker H, Hou Z, et al. Dietary betaine activates hepatic VTGII expression in laying hens associated with hypomethylation of GR gene promoter and enhanced GR expression. J Anim Sci Biotechnol. 2018;9:2 pubmed publisher
Zhang X, Feng Y, Wang X, Zhang Y, Yuan C, Zhang S, et al. The inhibition of UBC13 expression and blockage of the DNMT1-CHFR-Aurora A pathway contribute to paclitaxel resistance in ovarian cancer. Cell Death Dis. 2018;9:93 pubmed publisher
He Z, Zhang Y, Yang Y, Ma C, Wang P, Du W, et al. In Vivo Ovarian Cancer Gene Therapy Using CRISPR-Cas9. Hum Gene Ther. 2018;29:223-233 pubmed publisher
Idriss A, Hu Y, Hou Z, Hu Y, Sun Q, Omer N, et al. Dietary betaine supplementation in hens modulates hypothalamic expression of cholesterol metabolic genes in F1 cockerels through modification of DNA methylation. Comp Biochem Physiol B Biochem Mol Biol. 2018;217:14-20 pubmed publisher
He B, Yin C, Gong Y, Liu J, Guo H, Zhao R. Melatonin-induced increase of lipid droplets accumulation and in vitro maturation in porcine oocytes is mediated by mitochondrial quiescence. J Cell Physiol. 2018;233:302-312 pubmed publisher
Fan L, Cao X, Yan H, Wang Q, Tian X, Zhang L, et al. The synthetic antihyperlipidemic drug potassium piperate selectively kills breast cancer cells through inhibiting G1-S-phase transition and inducing apoptosis. Oncotarget. 2017;8:47250-47268 pubmed publisher
Qiu H, Zhong J, Luo L, Tang Z, Liu N, Kang K, et al. Regulatory Axis of miR-195/497 and HMGA1-Id3 Governs Muscle Cell Proliferation and Differentiation. Int J Biol Sci. 2017;13:157-166 pubmed publisher
Idriss A, Hu Y, Sun Q, Jia L, Jia Y, Omer N, et al. Prenatal betaine exposure modulates hypothalamic expression of cholesterol metabolic genes in cockerels through modifications of DNA methylation. Poult Sci. 2017;96:1715-1724 pubmed publisher
Wang X, Liang Z, Xu X, Li J, Zhu Y, Meng S, et al. miR-148a-3p represses proliferation and EMT by establishing regulatory circuits between ERBB3/AKT2/c-myc and DNMT1 in bladder cancer. Cell Death Dis. 2016;7:e2503 pubmed publisher
Zeng S, Yang Y, Cheng X, Zhou B, Li P, Zhao Y, et al. HIC1 epigenetically represses CIITA transcription in B lymphocytes. Biochim Biophys Acta. 2016;1859:1481-1489 pubmed publisher
Jia L, Li J, He B, Jia Y, Niu Y, Wang C, et al. Abnormally activated one-carbon metabolic pathway is associated with mtDNA hypermethylation and mitochondrial malfunction in the oocytes of polycystic gilt ovaries. Sci Rep. 2016;6:19436 pubmed publisher
Hu Y, Sun Q, Li X, Wang M, Cai D, Li X, et al. In Ovo injection of betaine affects hepatic cholesterol metabolism through epigenetic gene regulation in newly hatched chicks. PLoS ONE. 2015;10:e0122643 pubmed publisher
Li X, Sun Q, Li X, Cai D, Sui S, Jia Y, et al. Dietary betaine supplementation to gestational sows enhances hippocampal IGF2 expression in newborn piglets with modified DNA methylation of the differentially methylated regions. Eur J Nutr. 2015;54:1201-10 pubmed publisher

product information

CatalogNo :

24206-1-AP

AntigenName :

DNMT1

Package :

150UL

Price :

299 USD

Exsists20ul :

20ul trial size available

FullName :

DNA (cytosine-5-)-methyltransferase 1

Immunogen :

Fusion Protein

Species :

chicken, gilt, human, pig, rat, swine

Host :

Rabbit

IsConjugated :

Unconjugated

AntigenSpecies :

human

Application :

WB, IP, IF, ELISA

Clonlity :

Polyclonal

IsoType :

IgG

Synonyms :

AIM, CXXC9, DNA methyltransferase HsaI, DNA MTase HsaI, DNMT, DNMT1, FLJ16293, M.HsaI, MCMT

PrimaryOrSecondary :

Primary

AntibodyBuffer :

PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

GenBankNo :

BC126227

Category :

Binding Proteins;Cytoskeleton/Scaffold Proteins;Metabolism;

PurifyMethod :

Antigen affinity purification

NewAb :

False

IsSellable :

True

Feature :

siRNA

AppTiter :

IF 1:25 ; IP 1:500 ; WB 1:300 ;