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- western blot; mouse; 1:2000; loading ...; fig s5a
| Zhu P, Khatiwada S, Cui Y, Reineke L, Dooling S, Kim J, et al. Activation of the ISR mediates the behavioral and neurophysiological abnormalities in Down syndrome. Science. 2019;366:843-849 pubmed publisher
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- western blot; mouse; loading ...; fig 2b
| Schiattarella G, Altamirano F, Tong D, French K, Villalobos E, Kim S, et al. Nitrosative stress drives heart failure with preserved ejection fraction. Nature. 2019;568:351-356 pubmed publisher
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- western blot; human; 1:1000; loading ...; fig 5a
| Yue X, Zuo Y, Ke H, Luo J, Lou L, Qin W, et al. Identification of 4-arylidene curcumin analogues as novel proteasome inhibitors for potential anticancer agents targeting 19S regulatory particle associated deubiquitinase. Biochem Pharmacol. 2017;137:29-50 pubmed publisher
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- western blot; rat; 1:5000; loading ...; fig 7a
| Kim J, Ko A, Hyun H, Min S, Kim J. PDI regulates seizure activity via NMDA receptor redox in rats. Sci Rep. 2017;7:42491 pubmed publisher
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- western blot; mouse; fig 4
| Lin Y, Zhuang J, Li H, Zhu G, Zhou S, Li W, et al. Vaspin attenuates the progression of atherosclerosis by inhibiting ER stress-induced macrophage apoptosis in apoE‑/‑ mice. Mol Med Rep. 2016;13:1509-16 pubmed publisher
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| Su W, Tai Y, Tang S, Ye Y, Zhao C, Gao J, et al. Celecoxib attenuates hepatocyte apoptosis by inhibiting endoplasmic reticulum stress in thioacetamide-induced cirrhotic rats. World J Gastroenterol. 2020;26:4094-4107 pubmed publisher
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| Zhang D, Fan R, Lei L, Lei L, Wang Y, Lv N, et al. Cell cycle exit during bortezomib-induced osteogenic differentiation of mesenchymal stem cells was mediated by Xbp1s-upregulated p21Cip1 and p27Kip1. J Cell Mol Med. 2020;: pubmed publisher
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| Zhao H, Wang Y, Li B, Zheng T, Liu X, Hu B, et al. Role of Endoplasmic Reticulum Stress in Otitis Media. Front Genet. 2020;11:495 pubmed publisher
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| Liu H, Xie S, Fang F, Kalvakolanu D, Xiao W. SHQ1 is an ER stress response gene that facilitates chemotherapeutics-induced apoptosis via sensitizing ER-stress response. Cell Death Dis. 2020;11:445 pubmed publisher
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| Wang Y, Chen J, Li S, Zhang X, Guo Z, Hu J, et al. Exogenous spermine attenuates rat diabetic cardiomyopathy via suppressing ROS-p53 mediated downregulation of calcium-sensitive receptor. Redox Biol. 2020;32:101514 pubmed publisher
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| YAO Y. Ginsenosides reduce body weight and ameliorate hepatic steatosis in high fat diet‑induced obese mice via endoplasmic reticulum stress and p‑STAT3/STAT3 signaling. Mol Med Rep. 2020;21:1059-1070 pubmed publisher
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| Wang Z, Chang L, Wu J, Pan H, Zhang Q, Wang M, et al. A novel rhynchophylline analog, Y396, inhibits endothelial dysfunction induced by oxidative stress in diabetes through EGF receptor. Antioxid Redox Signal. 2019;: pubmed publisher
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| Huang C, Hedl M, Ranjan K, Abraham C. LACC1 Required for NOD2-Induced, ER Stress-Mediated Innate Immune Outcomes in Human Macrophages and LACC1 Risk Variants Modulate These Outcomes. Cell Rep. 2019;29:4525-4539.e4 pubmed publisher
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| Gao P, Chai Y, Song J, Liu T, Chen P, Zhou L, et al. Reprogramming the unfolded protein response for replication by porcine reproductive and respiratory syndrome virus. PLoS Pathog. 2019;15:e1008169 pubmed publisher
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| Cheng F, Lee Y, Hsu Y, Chiu I, Chiu Y, Lin Y, et al. Promising therapeutic effect of thapsigargin nanoparticles on chronic kidney disease through the activation of Nrf2 and FoxO1. Aging (Albany NY). 2019;11:9875-9892 pubmed publisher
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| Ma Y, Di Z, Cao Q, Xu W, Bi S, Yu J, et al. Xanthatin induces glioma cell apoptosis and inhibits tumor growth via activating endoplasmic reticulum stress-dependent CHOP pathway. Acta Pharmacol Sin. 2019;: pubmed publisher
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| Tang Q, Ren L, Liu J, Li W, Zheng X, Wang J, et al. Withaferin A triggers G2/M arrest and intrinsic apoptosis in glioblastoma cells via ATF4-ATF3-CHOP axis. Cell Prolif. 2019;:e12706 pubmed publisher
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| Hu J, Wu Q, Wang Z, Hong J, Chen R, Li B, et al. Inhibition of CACNA1H attenuates doxorubicin-induced acute cardiotoxicity by affecting endoplasmic reticulum stress. Biomed Pharmacother. 2019;120:109475 pubmed publisher
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| Chen J, Hung C, Keller J, Lin H, Wu Y. Proteomic analysis of retinal pigment epithelium cells after exposure to UVA radiation. BMC Ophthalmol. 2019;19:168 pubmed publisher
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| Li C, Pan Y, Gao Y, Shi F, Wang Y, Sun X. Autophagy protects HUVECs against ER stress-mediated apoptosis under simulated microgravity. Apoptosis. 2019;24:812-825 pubmed publisher
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| Nan D, Jin H, Deng J, Yu W, Liu R, Sun W, et al. Cilostazol ameliorates ischemia/reperfusion-induced tight junction disruption in brain endothelial cells by inhibiting endoplasmic reticulum stress. FASEB J. 2019;33:10152-10164 pubmed publisher
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| Xu W, Wu Y, Hu Z, Sun L, Dou G, Zhang Z, et al. Exosomes from Microglia Attenuate Photoreceptor Injury and Neovascularization in an Animal Model of Retinopathy of Prematurity. Mol Ther Nucleic Acids. 2019;16:778-790 pubmed publisher
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| Sun J, Liu Y, Yu J, Wu J, Gao W, Ran L, et al. Effects of APS Activates Hepatic Insulin Signaling in HFD-induced IR Mice. J Mol Endocrinol. 2019;: pubmed publisher
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| Wu Y, Su T, Dai G, Su J, Liu C. Flaccidoxide-13-Acetate-Induced Apoptosis in Human Bladder Cancer Cells is through Activation of p38/JNK, Mitochondrial Dysfunction, and Endoplasmic Reticulum Stress Regulated Pathway. Mar Drugs. 2019;17: pubmed publisher
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| Zhao Y, Yan J, Li A, Zhang Z, Li Z, Guo K, et al. Bone marrow mesenchymal stem cells could reduce the toxic effects of hexavalent chromium on the liver by decreasing endoplasmic reticulum stress-mediated apoptosis via SIRT1/HIF-1α signaling pathway in rats. Toxicol Lett. 2019;310:31-38 pubmed publisher
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| Guo Q, Hu H, Liu X, Yang D, Yin Y, Zhang B, et al. C/EBPβ mediates palmitate-induced musclin expression via the regulation of PERK/ATF4 pathways in myotubes. Am J Physiol Endocrinol Metab. 2019;316:E1081-E1092 pubmed publisher
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| Wu S, Zhu X, Guo B, Zheng T, Ren J, Zeng W, et al. Unfolded Protein Response Pathways Correlatively Modulate Endoplasmic Reticulum Stress Responses in Rat Retinal Müller Cells. J Ophthalmol. 2019;2019:9028483 pubmed publisher
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| Cao X, He Y, Li X, Xu Y, Liu X. The IRE1α-XBP1 pathway function in hypoxia-induced pulmonary vascular remodeling, is upregulated by quercetin, inhibits apoptosis and partially reverses the effect of quercetin in PASMCs. Am J Transl Res. 2019;11:641-654 pubmed
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| Zhang L, Wang B, Xin Q, Shang W, Shen S, Xiao G, et al. Quantitative Proteomic Analysis Reveals Unfolded-Protein Response Involved in Severe Fever with Thrombocytopenia Syndrome Virus Infection. J Virol. 2019;93: pubmed publisher
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| Huang C, Yao R, Zhu Z, Pang D, Cao X, Feng B, et al. A pectic polysaccharide from water decoction of Xinjiang Lycium barbarum fruit protects against intestinal endoplasmic reticulum stress. Int J Biol Macromol. 2019;130:508-514 pubmed publisher
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| Xu S, Di Z, He Y, Wang R, Ma Y, Sun R, et al. Mesencephalic astrocyte-derived neurotrophic factor (MANF) protects against Aβ toxicity via attenuating Aβ-induced endoplasmic reticulum stress. J Neuroinflammation. 2019;16:35 pubmed publisher
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| Zhou M, Feng Z, Ou Y, Peng J, Li K, Gong H, et al. Endoplasmic reticulum stress induces apoptosis of arginine vasopressin neurons in central diabetes insipidus via PI3K/Akt pathway. CNS Neurosci Ther. 2019;25:562-574 pubmed publisher
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| Blackwood E, Azizi K, Thuerauf D, Paxman R, Plate L, Kelly J, et al. Pharmacologic ATF6 activation confers global protection in widespread disease models by reprograming cellular proteostasis. Nat Commun. 2019;10:187 pubmed publisher
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| Ullah O, Li Z, Ali I, Xu L, Liu H, Jin H, et al. Pterostilbene exerts a protective effect via regulating tunicamycin-induced endoplasmic reticulum stress in mouse preimplantation embryos. In Vitro Cell Dev Biol Anim. 2019;55:82-93 pubmed publisher
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| Hong J, Hu Z, Wu Q, Tang C, Hu J, Chen R, et al. The deregulation of STIM1 and store operative calcium entry impaired aortic smooth muscle cells contractility in aortic medial degeneration. Biosci Rep. 2019;39: pubmed publisher
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| Hu H, Wang C, Jin Y, Meng Q, Liu Q, Liu Z, et al. Catalpol Inhibits Homocysteine-induced Oxidation and Inflammation via Inhibiting Nox4/NF-κB and GRP78/PERK Pathways in Human Aorta Endothelial Cells. Inflammation. 2019;42:64-80 pubmed publisher
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| Liu X, Wang J, Gao L, Jiao Y, Liu C. Maternal Protein Restriction Induces Alterations in Hepatic Unfolded Protein Response-Related Molecules in Adult Rat Offspring. Front Endocrinol (Lausanne). 2018;9:676 pubmed publisher
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| Morimoto M, Waller Evans H, Ammous Z, Song X, Strauss K, Pehlivan D, et al. Bi-allelic CCDC47 Variants Cause a Disorder Characterized by Woolly Hair, Liver Dysfunction, Dysmorphic Features, and Global Developmental Delay. Am J Hum Genet. 2018;103:794-807 pubmed publisher
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| Ingles J, Simpson A, Kyathanahalli C, Anamthathmakula P, Hassan S, Jeyasuria P, et al. Preconditioning the uterine unfolded protein response maintains non-apoptotic Caspase 3-dependent quiescence during pregnancy. Cell Death Dis. 2018;9:933 pubmed publisher
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| Tsai T, Lai K, Su J, Wu Y, Sheu J. 7-Acetylsinumaximol B Induces Apoptosis and Autophagy in Human Gastric Carcinoma Cells through Mitochondria Dysfunction and Activation of the PERK/eIF2α/ATF4/CHOP Signaling Pathway. Mar Drugs. 2018;16: pubmed publisher
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| Niu X, Zhang J, Ling C, Bai M, Peng Y, Sun S, et al. Polysaccharide from Angelica sinensis protects H9c2 cells against oxidative injury and endoplasmic reticulum stress by activating the ATF6 pathway. J Int Med Res. 2018;46:1717-1733 pubmed publisher
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| Liu Z, Wang Y, Wang Y, Dong W, Xia X, Song E, et al. Effect of Subcellular Translocation of Protein Disulfide Isomerase on Tetrachlorobenzoquinone-Induced Signaling Shift from Endoplasmic Reticulum Stress to Apoptosis. Chem Res Toxicol. 2017;30:1804-1814 pubmed publisher
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| Liu Y, Jiang Z, Zhou Y, Qiu H, Wang G, Luo Y, et al. β-elemene regulates endoplasmic reticulum stress to induce the apoptosis of NSCLC cells through PERK/IRE1α/ATF6 pathway. Biomed Pharmacother. 2017;93:490-497 pubmed publisher
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| Han K, Hassanzadeh S, Singh K, Menazza S, Nguyen T, Stevens M, et al. Parkin regulation of CHOP modulates susceptibility to cardiac endoplasmic reticulum stress. Sci Rep. 2017;7:2093 pubmed publisher
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| Sheng L, Cai L, Liu J, Zhang S, Xu J, Zhang X, et al. Imaging specific newly synthesized proteins within cells by fluorescence resonance energy transfer. Chem Sci. 2017;8:748-754 pubmed publisher
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| Wang Y, Wu H, Li Z, Yang P, Li Z. A positive feedback loop between GRP78 and VPS34 is critical for GRP78-mediated autophagy in cancer cells. Exp Cell Res. 2017;351:24-35 pubmed publisher
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| Yang F, Yu X, Li T, Wu J, Zhao Y, Liu J, et al. Exogenous H2S regulates endoplasmic reticulum-mitochondria cross-talk to inhibit apoptotic pathways in STZ-induced type I diabetes. Am J Physiol Endocrinol Metab. 2017;312:E190-E203 pubmed publisher
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| Jin J, Blackwood E, Azizi K, Thuerauf D, Fahem A, Hofmann C, et al. ATF6 Decreases Myocardial Ischemia/Reperfusion Damage and Links ER Stress and Oxidative Stress Signaling Pathways in the Heart. Circ Res. 2017;120:862-875 pubmed publisher
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| Lin J, Wang R, Chen J, Chiu C, Liao M, Wu Y. Cytotoxicity of 11-epi-Sinulariolide Acetate Isolated from Cultured Soft Corals on HA22T Cells through the Endoplasmic Reticulum Stress Pathway and Mitochondrial Dysfunction. Int J Mol Sci. 2016;17: pubmed
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| Liu J, Xiao M, Li J, Wang D, He Y, He J, et al. Activation of UPR Signaling Pathway is Associated With the Malignant Progression and Poor Prognosis in Prostate Cancer. Prostate. 2017;77:274-281 pubmed publisher
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