This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Proteintech Group
product type :
antibody
product name :
Rac1
catalog :
24072-1-AP
quantity :
150UL
price :
299 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry
citations: 22
Reference
Pang Y, Zhao Y, Wang Y, Wang X, Wang R, Liu N, et al. TNFAIP8 promotes AML chemoresistance by activating ERK signaling pathway through interaction with Rac1. J Exp Clin Cancer Res. 2020;39:158 pubmed publisher
Qi Y, Liang X, Dai F, Guan H, Sun J, Yao W. RhoA/ROCK Pathway Activation is Regulated by AT1 Receptor and Participates in Smooth Muscle Migration and Dedifferentiation via Promoting Actin Cytoskeleton Polymerization. Int J Mol Sci. 2020;21: pubmed publisher
Bin J, Nie S, Tang Z, Kang A, Fu Z, Hu Y, et al. Long noncoding RNA EPB41L4A-AS1 functions as an oncogene by regulating the Rho/ROCK pathway in colorectal cancer. J Cell Physiol. 2020;: pubmed publisher
Li M, Min W, Wang J, Wang L, Li Y, Zhou N, et al. Effects of mevalonate kinase interference on cell differentiation, apoptosis, prenylation and geranylgeranylation of human keratinocytes are attenuated by farnesyl pyrophosphate or geranylgeranyl pyrophosphate. Exp Ther Med. 2020;19:2861-2870 pubmed publisher
Zhang B, Zhong X, Sauane M, Zhao Y, Zheng Z. Modulation of the Pol II CTD Phosphorylation Code by Rac1 and Cdc42 Small GTPases in Cultured Human Cancer Cells and Its Implication for Developing a Synthetic-Lethal Cancer Therapy. Cells. 2020;9: pubmed publisher
Kang Y, Liu J, Yin S, Jiang Y, Feng X, Wu J, et al. Oxidation of Reduced Graphene Oxide via Cellular Redox Signaling Modulates Actin-Mediated Neurotransmission. ACS Nano. 2020;14:3059-3074 pubmed publisher
Xu Z, Hao T, Gan Y. RhoG/Rac1 signaling pathway involved in migration and invasion of salivary adenoid cystic carcinoma cells. Oral Dis. 2019;: pubmed publisher
Zhou Y, Wang Y, Zhou W, Chen T, Wu Q, Chutturghoon V, et al. YAP promotes multi-drug resistance and inhibits autophagy-related cell death in hepatocellular carcinoma via the RAC1-ROS-mTOR pathway. Cancer Cell Int. 2019;19:179 pubmed publisher
Song Y, Tang C, Yin C. Combination antitumor immunotherapy with VEGF and PIGF siRNA via systemic delivery of multi-functionalized nanoparticles to tumor-associated macrophages and breast cancer cells. Biomaterials. 2018;185:117-132 pubmed publisher
Chen X, Zhang J, Luo J, Wu S, Yuan G, Ma N, et al. CSTF2-Induced Shortening of the RAC1 3'UTR Promotes the Pathogenesis of Urothelial Carcinoma of the Bladder. Cancer Res. 2018;78:5848-5862 pubmed publisher
Sun X, Liu S, Wang J, Wei B, Guo C, Chen C, et al. Annexin A5 regulates hepatocarcinoma malignancy via CRKI/II-DOCK180-RAC1 integrin and MEK-ERK pathways. Cell Death Dis. 2018;9:637 pubmed publisher
Zhao Q, Liu Z, Huang B, Yuan Y, Liu X, Zhang H, et al. PEDF improves cardiac function in rats subjected to myocardial ischemia/reperfusion injury by inhibiting ROS generation via PEDF?R. Int J Mol Med. 2018;41:3243-3252 pubmed publisher
Cheng H, Wang W, Wang G, Wang A, Du L, Lou W. Silencing Ras-Related C3 Botulinum Toxin Substrate 1 Inhibits Growth and Migration of Hypopharyngeal Squamous Cell Carcinoma via the P38 Mitogen-Activated Protein Kinase Signaling Pathway. Med Sci Monit. 2018;24:768-781 pubmed
Liang D, Wang Z, Yan Z, Hou S, Xu W, Wang L, et al. Nicotine facilitates VSMC dysfunction through a miR-200b/RhoGDIA/cytoskeleton module. Sci Rep. 2017;7:43798 pubmed publisher
Yi H, Hu W, Chen S, Lu Z, Wang Y. Cathelicidin-WA Improves Intestinal Epithelial Barrier Function and Enhances Host Defense against Enterohemorrhagic Escherichia coli O157:H7 Infection. J Immunol. 2017;198:1696-1705 pubmed publisher
Li Y, Wang Y, Kong R, Xue D, Pan S, Chen H, et al. Dihydroartemisinin suppresses pancreatic cancer cells via a microRNA-mRNA regulatory network. Oncotarget. 2016;7:62460-62473 pubmed publisher
Dai B, Wang W, Ma Y, Liu R, Zhang Y. A taspine derivative supresses Caco-2 cell growth by competitively targeting EphrinB2 and regulating its pathway. Oncol Rep. 2016;36:1526-34 pubmed publisher
Yu J, Lin S, Wang M, Liang L, Zou Z, Zhou X, et al. Metastasis suppressor 1 regulates neurite outgrowth in primary neuron cultures. Neuroscience. 2016;333:123-31 pubmed publisher
Zhu J, Wang S, Zhang W, Qiu J, Shan Y, Yang D, et al. Screening key microRNAs for castration-resistant prostate cancer based on miRNA/mRNA functional synergistic network. Oncotarget. 2015;6:43819-30 pubmed publisher
Kan H, Hu W, Wang Y, Wu W, Yin Y, Liang Y, et al. NADPH oxidase-derived production of reactive oxygen species is involved in learning and memory impairments in 16-month-old female rats. Mol Med Rep. 2015;12:4546-4553 pubmed publisher
Wang B, Fang J, Qu L, Cao Z, Zhou J, Deng B. Upregulated TRIO expression correlates with a malignant phenotype in human hepatocellular carcinoma. Tumour Biol. 2015;36:6901-8 pubmed publisher
Ying L, Li G, Wei S, Wang H, An P, Wang X, et al. Sanguinarine inhibits Rac1b-rendered cell survival enhancement by promoting apoptosis and blocking proliferation. Acta Pharmacol Sin. 2015;36:229-40 pubmed publisher
product information
CatalogNo :
24072-1-AP
AntigenName :
Rac1
Package :
150UL
Price :
299 USD
Exsists20ul :
20ul trial size available
FullName :
ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
Immunogen :
Fusion Protein
Species :
human, mouse, rat
Host :
Rabbit
IsConjugated :
Unconjugated
AntigenSpecies :
human
Application :
WB, IHC, IF, coIP, ELISA
Clonlity :
Polyclonal
IsoType :
IgG
Synonyms :
MIG5, RAC1, RAC1b, Ras like protein TC25, TC 25, TC25
PrimaryOrSecondary :
Primary
AntibodyBuffer :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
GenBankNo :
BC004247
Category :
Binding Proteins;Cytoskeleton/Scaffold Proteins;Membrane Proteins;Signal transduction;
PurifyMethod :
Antigen affinity purification
NewAb :
False
IsSellable :
True
Feature :
siRNA
AppTiter :
IF 1:200 ; WB 1:800 ;
company information
Proteintech Group
2201 W. Campbell Park Dr. STE12
Chicago, IL 60612
Proteintech@ptglab.com
https://www.ptglab.com
1-312-455-8498
headquarters: USA
At Proteintech, we produce every single antibody we sell; we do not rely on or supply to any other antibody providers: our products are unique and we are 100% accountable for each one. We realize this accountability by validating in-house, providing extensive technical support and guaranteeing your success: in addition to helping you troubleshoot your experiment, we will offer you a full cash refund if you are in any way dissatisfied. We can guarantee satisfaction because we have confidence in our products, confidence cultivated by the science behind our antibodies: we make them using as much of the native protein as possible, and purifying them using affinity purification with the original antigen. We carry out antibody production over a 102-day period, which allows for better antigen fitting to MHC molecules and affinity maturation in the host. This approach results in higher affinity antibodies with greater sensitivity, which you can use in any application and in multiple species.
You can only buy Proteintech antibodies directly from Proteintech or via one of its approved distributors — when you receive your antibody and see the Proteintech logo on the vial, know that you hold something that is truly unique.