This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Proteintech Group
product type :
antibody
product name :
Glucocorticoid receptor
catalog :
24050-1-AP
quantity :
150UL
price :
299 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, chromatin immunoprecipitation
citations: 26
Reference
Wang L, Cheng C, Qin J, Xu M, Kao C, Shi J, et al. Small-molecule inhibitor targeting orphan nuclear receptor COUP-TFII for prostate cancer treatment. Sci Adv. 2020;6:eaaz8031 pubmed publisher
Kershaw S, Morgan D, Boyd J, Spiller D, Kitchen G, Zindy E, et al. Glucocorticoids rapidly inhibit cell migration through a novel, non-transcriptional HDAC6 pathway. J Cell Sci. 2020;133: pubmed publisher
Quagliarini F, Mir A, Balazs K, Wierer M, Dyar K, Jouffe C, et al. Cistromic Reprogramming of the Diurnal Glucocorticoid Hormone Response by High-Fat Diet. Mol Cell. 2019;76:531-545.e5 pubmed publisher
Xu B, Lang L, Li S, Yuan J, Wang J, Yang H, et al. Corticosterone Excess-Mediated Mitochondrial Damage Induces Hippocampal Neuronal Autophagy in Mice Following Cold Exposure. Animals (Basel). 2019;9: pubmed publisher
Wang D, Xu B, Wang J, Wang H, Guo J, Ji H, et al. Response of the maternal hypothalamus to cold stress during late pregnancy in rats. Brain Res. 2019;1722:146354 pubmed publisher
Xu B, Lang L, Li S, Guo J, Wang J, Wang D, et al. Cortisol Excess-Mediated Mitochondrial Damage Induced Hippocampal Neuronal Apoptosis in Mice Following Cold Exposure. Cells. 2019;8: pubmed publisher
Zhao N, Yang S, Sun B, Feng Y, Zhao R. Maternal betaine protects rat offspring from glucocorticoid-induced activation of lipolytic genes in adipose tissue through modification of DNA methylation. Eur J Nutr. 2019;: pubmed publisher
Hunter A, Narang N, Baxter M, Ray D, Poolman T. An improved method for quantitative ChIP studies of nuclear receptor function. J Mol Endocrinol. 2019;62:169-177 pubmed publisher
Hemmer M, Wierer M, Schachtrup K, Downes M, Hubner N, Evans R, et al. E47 modulates hepatic glucocorticoid action. Nat Commun. 2019;10:306 pubmed publisher
Lian S, Xu B, Wang D, Wang L, Li W, Yao R, et al. Possible mechanisms of prenatal cold stress induced-anxiety-like behavior depression in offspring rats. Behav Brain Res. 2019;359:304-311 pubmed publisher
Liao L, Wang X, Yao X, Zhang B, Zhou L, Huang J. Gestational stress induced differential expression of HDAC2 in male rat offspring hippocampus during development. Neurosci Res. 2018;: pubmed publisher
Li Y, Qin J, Yan J, Zhang N, Xu Y, Zhu Y, et al. Differences of physical vs. psychological stress: evidences from glucocorticoid receptor expression, hippocampal subfields injury, and behavioral abnormalities. Brain Imaging Behav. 2018;: pubmed publisher
Caratti G, Iqbal M, Hunter L, Kim D, Wang P, Vonslow R, et al. REVERBa couples the circadian clock to hepatic glucocorticoid action. J Clin Invest. 2018;128:4454-4471 pubmed publisher
Cheng K, Liu X, Chen L, Lv J, Qu F, Pan X, et al. α-Viniferin activates autophagic apoptosis and cell death by reducing glucocorticoid receptor expression in castration-resistant prostate cancer cells. Med Oncol. 2018;35:105 pubmed publisher
Liang M, Wang Z, Li H, Cai L, Pan J, He H, et al. l-Arginine induces antioxidant response to prevent oxidative stress via stimulation of glutathione synthesis and activation of Nrf2 pathway. Food Chem Toxicol. 2018;115:315-328 pubmed publisher
Lian S, Wang D, Xu B, Guo W, Wang L, Li W, et al. Prenatal cold stress: Effect on maternal hippocampus and offspring behavior in rats. Behav Brain Res. 2018;346:1-10 pubmed publisher
Zhao N, Yang S, Jia Y, Sun B, He B, Zhao R. Maternal betaine supplementation attenuates glucocorticoid-induced hepatic lipid accumulation through epigenetic modification in adult offspring rats. J Nutr Biochem. 2018;54:105-112 pubmed publisher
Lian S, Guo J, Wang L, Li W, Wang J, Ji H, et al. Impact of prenatal cold stress on placental physiology, inflammatory response, and apoptosis in rats. Oncotarget. 2017;8:115304-115314 pubmed publisher
Ptushkina M, Poolman T, Iqbal M, Ashe M, Petersen J, Woodburn J, et al. A non-transcriptional role for the glucocorticoid receptor in mediating the cell stress response. Sci Rep. 2017;7:12101 pubmed publisher
McCaffrey J, Webb N, Poolman T, Fresquet M, Moxey C, Zeef L, et al. Glucocorticoid therapy regulates podocyte motility by inhibition of Rac1. Sci Rep. 2017;7:6725 pubmed publisher
Zhong X, Tian S, Zhang X, Diao X, Dong F, Yang J, et al. CUE domain-containing protein 2 promotes the Warburg effect and tumorigenesis. EMBO Rep. 2017;18:809-825 pubmed publisher
Xu C, Zhang Y, Wang Q, Xu Z, Jiang J, Gao Y, et al. Long non-coding RNA GAS5 controls human embryonic stem cell self-renewal by maintaining NODAL signalling. Nat Commun. 2016;7:13287 pubmed publisher
Peng L, He Q, Li X, Shuai L, Chen H, Li Y, et al. HOXA13 exerts a beneficial effect in albumin-induced epithelial-mesenchymal transition via the glucocorticoid receptor signaling pathway in human renal tubular epithelial cells. Mol Med Rep. 2016;14:271-6 pubmed publisher
Liu X, Xie B, Wang Z, Jin L, Zhang Y. The secretion, synthesis, and metabolism of cortisol and its downstream genes in the H-P-I axis of rare minnows (Gobiocypris rarus) are disrupted by acute waterborne cadmium exposure. Comp Biochem Physiol C Toxicol Pharmacol. 2016;185-186:112-121 pubmed publisher
Li P, Zhang D, Shen L, Dong K, Wu M, Ou Z, et al. Redox homeostasis protects mitochondria through accelerating ROS conversion to enhance hypoxia resistance in cancer cells. Sci Rep. 2016;6:22831 pubmed publisher
Matthews L, Berry A, Morgan D, Poolman T, Bauer K, Kramer F, et al. Glucocorticoid receptor regulates accurate chromosome segregation and is associated with malignancy. Proc Natl Acad Sci U S A. 2015;112:5479-84 pubmed publisher
product information
CatalogNo :
24050-1-AP
AntigenName :
Glucocorticoid receptor
Package :
150UL
Price :
299 USD
Exsists20ul :
20ul trial size available
FullName :
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
Immunogen :
Fusion Protein
Species :
human, mouse, rare minnows, rat
Host :
Rabbit
IsConjugated :
Unconjugated
AntigenSpecies :
human
Application :
WB, IP, IHC, IF, CoIP, chIP, ELISA
Clonlity :
Polyclonal
IsoType :
IgG
Synonyms :
GCCR, GCR, Glucocorticoid receptor, GR, GRL, NR3C1
PrimaryOrSecondary :
Primary
AntibodyBuffer :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
GenBankNo :
BC015610
Category :
Binding Proteins;Cytoskeleton/Scaffold Proteins;Membrane Proteins;Metabolism;Signal transduction;
PurifyMethod :
Antigen affinity purification
NewAb :
False
IsSellable :
True
Feature :
siRNA
AppTiter :
IF 1:50 ; IHC 1:200 ; IP 1:500 ; WB 1:8000 ;
company information
Proteintech Group
2201 W. Campbell Park Dr. STE12
Chicago, IL 60612
Proteintech@ptglab.com
https://www.ptglab.com
1-312-455-8498
headquarters: USA
At Proteintech, we produce every single antibody we sell; we do not rely on or supply to any other antibody providers: our products are unique and we are 100% accountable for each one. We realize this accountability by validating in-house, providing extensive technical support and guaranteeing your success: in addition to helping you troubleshoot your experiment, we will offer you a full cash refund if you are in any way dissatisfied. We can guarantee satisfaction because we have confidence in our products, confidence cultivated by the science behind our antibodies: we make them using as much of the native protein as possible, and purifying them using affinity purification with the original antigen. We carry out antibody production over a 102-day period, which allows for better antigen fitting to MHC molecules and affinity maturation in the host. This approach results in higher affinity antibodies with greater sensitivity, which you can use in any application and in multiple species.
You can only buy Proteintech antibodies directly from Proteintech or via one of its approved distributors — when you receive your antibody and see the Proteintech logo on the vial, know that you hold something that is truly unique.