This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Proteintech Group
product type :
antibody
product name :
CTGF
catalog :
23936-1-AP
quantity :
150UL
price :
299 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry
citations: 40
Published Application/Species/Sample/DilutionReference
  • western blot; rat; 1:1000; loading ...; fig 7d
Tran B, Yu Y, Chang L, Tan B, Jia W, Xiong Y, et al. A Novel Liposomal S-Propargyl-Cysteine: A Sustained Release of Hydrogen Sulfide Reducing Myocardial Fibrosis via TGF-β1/Smad Pathway. Int J Nanomedicine. 2019;14:10061-10077 pubmed publisher
  • western blot; mouse; loading ...; fig 4c
Feng F, Wang Z, Li R, Wu Q, Gu C, Xu Y, et al. Citrus alkaline extracts prevent fibroblast senescence to ameliorate pulmonary fibrosis via activation of COX-2. Biomed Pharmacother. 2019;112:108669 pubmed publisher
Xu D, Chen P, Zheng P, Yin F, Cheng Q, Zhou Z, et al. KLF4 initiates sustained YAP activation to promote renal fibrosis in mice after ischemia-reperfusion kidney injury. Acta Pharmacol Sin. 2020;: pubmed publisher
Su C, Wang Q, Luo H, Jiao W, Tang J, Li L, et al. Si-Miao-Yong-An decoction attenuates cardiac fibrosis via suppressing TGF-β1 pathway and interfering with MMP-TIMPs expression. Biomed Pharmacother. 2020;127:110132 pubmed publisher
Hsu Y, Chiu I, Lin Y, Chen Y, Lee Y, Chiu H. Lactoferrin Contributes a Renoprotective Effect in Acute Kidney Injury and Early Renal Fibrosis. Pharmaceutics. 2020;12: pubmed publisher
Yang X, Li S, Wu Y, Ge F, Chen Y, Xiong Q. The circular RNA CDR1as regulate cell proliferation via TMED2 and TMED10. BMC Cancer. 2020;20:312 pubmed publisher
Zheng Y, Li Z, Lei L, Liu C, Wang Z, Fei L, et al. FAM83A Promotes Lung Cancer Progression by Regulating the Wnt and Hippo Signaling Pathways and Indicates Poor Prognosis. Front Oncol. 2020;10:180 pubmed publisher
Yao L, Zhou B, You L, Hu H, Xie R. LncRNA MIAT/miR-133a-3p axis regulates atrial fibrillation and atrial fibrillation-induced myocardial fibrosis. Mol Biol Rep. 2020;47:2605-2617 pubmed publisher
Sun L, Qu L, Brigstock D, Li H, Li Y, Gao R. Biological and Proteomic Characteristics of an Immortalized Human Pancreatic Stellate Cell Line. Int J Med Sci. 2020;17:137-144 pubmed publisher
Pei G, Xu L, Huang W, Yin J. The protective role of microRNA-133b in restricting hippocampal neurons apoptosis and inflammatory injury in rats with depression by suppressing CTGF. Int Immunopharmacol. 2020;78:106076 pubmed publisher
Jin W, Zhang Y, Xue Y, Han X, Zhang X, Ma Z, et al. Crocin attenuates isoprenaline-induced myocardial fibrosis by targeting TLR4/NF-κB signaling: connecting oxidative stress, inflammation, and apoptosis. Naunyn Schmiedebergs Arch Pharmacol. 2020;393:13-23 pubmed publisher
Rui Y, Chen M, Li Y, Xiao L, Geng P, Wang P, et al. CTGF Attenuates Tendon-Derived Stem/Progenitor Cell Aging. Stem Cells Int. 2019;2019:6257537 pubmed publisher
Shao J, Xu H, Wu X, Xu Y. Epigenetic activation of CTGF transcription by high glucose in renal tubular epithelial cells is mediated by myocardin-related transcription factor A. Cell Tissue Res. 2019;: pubmed publisher
Zhou X, Xiong J, Lu S, Luo L, Chen Z, Yang F, et al. Inhibitory Effect of Corilagin on miR-21-Regulated Hepatic Fibrosis Signaling Pathway. Am J Chin Med. 2019;47:1541-1569 pubmed publisher
Mao L, Liu L, Zhang T, Wu X, Zhang T, Xu Y. MKL1 mediates TGF-β-induced CTGF transcription to promote renal fibrosis. J Cell Physiol. 2019;: pubmed publisher
Wei P, Xie Y, Abel P, Huang Y, Ma Q, Li L, et al. Transforming growth factor (TGF)-β1-induced miR-133a inhibits myofibroblast differentiation and pulmonary fibrosis. Cell Death Dis. 2019;10:670 pubmed publisher
Zhang P, Chen F, Jia Q, Hu D. Upregulation of microRNA-133a and downregulation of connective tissue growth factor suppress cell proliferation, migration, and invasion in human glioma through the JAK/STAT signaling pathway. IUBMB Life. 2019;: pubmed publisher
Guo X, Zhu C, Liu X, Ge Y, Jiang X, Zhao W. Hyperoside protects against heart failure-induced liver fibrosis in rats. Acta Histochem. 2019;: pubmed publisher
Wang T, Fu X, Jin T, Zhang L, Liu B, Wu Y, et al. Aspirin targets P4HA2 through inhibiting NF-κB and LMCD1-AS1/let-7g to inhibit tumour growth and collagen deposition in hepatocellular carcinoma. EBioMedicine. 2019;45:168-180 pubmed publisher
Hsu Y, Chuang H, Lee Y, Lin Y, Chiu Y, Wang Y, et al. Induction of Fibrosis and Autophagy in Kidney Cells by Vinyl Chloride. Cells. 2019;8: pubmed publisher
Li M, Chen J, Yu X, Xu S, Li D, Zheng Q, et al. Myricetin Suppresses the Propagation of Hepatocellular Carcinoma via Down-Regulating Expression of YAP. Cells. 2019;8: pubmed publisher
Han W, Wang C, Yang Z, Mu L, Wu M, Chen N, et al. SRT1720 retards renal fibrosis via inhibition of HIF1α /GLUT1 in diabetic nephropathy. J Endocrinol. 2019;: pubmed publisher
Wang W, Li H, Yan J, Zhuang F, Bao M, Liu J, et al. CTGF regulates cyclic stretch-induced vascular smooth muscle cell proliferation via microRNA-19b-3p. Exp Cell Res. 2019;: pubmed publisher
Chen C, Juan S, Chou H. Hyperglycemia activates the renin-angiotensin system and induces epithelial-mesenchymal transition in streptozotocin-induced diabetic kidneys. J Renin Angiotensin Aldosterone Syst. 2018;19:1470320318803009 pubmed publisher
Wang Y, Chen M. Decreased expression of LATS1 correlates with astrogliosis after spinal cord injury. Biochem Biophys Res Commun. 2018;505:151-156 pubmed publisher
Wang Q, Zang W, Han L, Yang L, Ye S, Ouyang J, et al. Wenyang Huazhuo Tongluo formula inhibits fibrosis via suppressing Wnt/β-catenin signaling pathway in a Bleomycin-induced systemic sclerosis mouse model. Chin Med. 2018;13:17 pubmed publisher
Gao M, Chen M, Li C, Xu M, Liu Y, Cong M, et al. Long non-coding RNA MT1DP shunts the cellular defense to cytotoxicity through crosstalk with MT1H and RhoC in cadmium stress. Cell Discov. 2018;4:5 pubmed publisher
Zhang X, Ma Z, Yuan Y, Xu S, Wei W, Song P, et al. Rosmarinic acid attenuates cardiac fibrosis following long-term pressure overload via AMPKα/Smad3 signaling. Cell Death Dis. 2018;9:102 pubmed publisher
Cui K, Tang Z, Li C, Wang T, Rao K, Wang S, et al. Lipoxin A4 improves erectile dysfunction in rats with type I diabetes by inhibiting oxidative stress and corporal fibrosis. Asian J Androl. 2018;20:166-172 pubmed publisher
Wang W, Deng A, He S. A key role of microRNA-26a in the scar formation after glaucoma filtration surgery. Artif Cells Nanomed Biotechnol. 2018;46:831-837 pubmed publisher
Yoon S, Kim J. Exogenous CGRP upregulates profibrogenic growth factors through PKC/JNK signaling pathway in kidney proximal tubular cells. Cell Biol Toxicol. 2018;34:251-262 pubmed publisher
Man Q, Ma Y, Liu J, Zhao Y, Liu B, Zhao Y. Expression of YAP/TAZ in Keratocystic Odontogenic Tumors and Its Possible Association with Proliferative Behavior. Biomed Res Int. 2017;2017:4624890 pubmed publisher
Wu Q, Xiao Y, Jiang X, Yuan Y, Yang Z, Chang W, et al. Evodiamine attenuates TGF-?1-induced fibroblast activation and endothelial to mesenchymal transition. Mol Cell Biochem. 2017;430:81-90 pubmed publisher
Deng J, Zhang W, Liu S, An H, Tan L, Ma L. LATS1 suppresses proliferation and invasion of cervical cancer. Mol Med Rep. 2017;15:1654-1660 pubmed publisher
Cui K, Ruan Y, Wang T, Rao K, Chen Z, Wang S, et al. FTY720 Supplementation Partially Improves Erectile Dysfunction in Rats With Streptozotocin-Induced Type 1 Diabetes Through Inhibition of Endothelial Dysfunction and Corporal Fibrosis. J Sex Med. 2017;14:323-335 pubmed publisher
Sa G, Xiong X, Ren J, Zhao Y, He S. Expression of fibrosis-related molecules in the oral mucosa of six animal species: A reference for selecting animal models. Eur J Pharm Sci. 2017;96:472-478 pubmed publisher
Tao L, Bei Y, Chen P, Lei Z, Fu S, Zhang H, et al. Crucial Role of miR-433 in Regulating Cardiac Fibrosis. Theranostics. 2016;6:2068-2083 pubmed
Li L, Fang R, Liu B, Shi H, Wang Y, Zhang W, et al. Deacetylation of tumor-suppressor MST1 in Hippo pathway induces its degradation through HBXIP-elevated HDAC6 in promotion of breast cancer growth. Oncogene. 2016;35:4048-57 pubmed publisher
Xu W, Wei Y, Wu S, Wang Y, Wang Z, Sun Y, et al. Up-regulation of the Hippo pathway effector TAZ renders lung adenocarcinoma cells harboring EGFR-T790M mutation resistant to gefitinib. Cell Biosci. 2015;5:7 pubmed publisher
Gao Y, Wang Y, Feng J, Feng G, Zheng M, Yang Z, et al. A hairpin within YAP mRNA 3'UTR functions in regulation at post-transcription level. Biochem Biophys Res Commun. 2015;459:306-312 pubmed publisher
product information
CatalogNo :
23936-1-AP
AntigenName :
CTGF
Package :
150UL
Price :
299 USD
Exsists20ul :
20ul trial size available
FullName :
connective tissue growth factor
Immunogen :
Fusion Protein
Species :
buffloa, dog, human, miniping, mouse, pig, rat, sheep
Host :
Rabbit
IsConjugated :
Unconjugated
AntigenSpecies :
human
Application :
WB, IHC, IF, ELISA
Clonlity :
Polyclonal
IsoType :
IgG
Synonyms :
CCN family member 2, CCN2, CTGF, HCS24, IBP 8, IGF binding protein 8, IGFBP 8, IGFBP8, NOV2
PrimaryOrSecondary :
Primary
AntibodyBuffer :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
GenBankNo :
BC087839
Category :
Binding Proteins;Cell Cycle;Cytoskeleton/Scaffold Proteins;Growth Factor/Cytokine/Hormone;Membrane Proteins;Metabolism;Signal transduction;
PurifyMethod :
Antigen affinity purification
NewAb :
False
IsSellable :
True
Feature :
siRNA
AppTiter :
IF 1:50 ; IHC 1:200 ; WB 1:600 ;
company information
Proteintech Group
2201 W. Campbell Park Dr. STE12
Chicago, IL 60612
Proteintech@ptglab.com
https://www.ptglab.com
1-312-455-8498
headquarters: USA
At Proteintech, we produce every single antibody we sell; we do not rely on or supply to any other antibody providers: our products are unique and we are 100% accountable for each one. We realize this accountability by validating in-house, providing extensive technical support and guaranteeing your success: in addition to helping you troubleshoot your experiment, we will offer you a full cash refund if you are in any way dissatisfied. We can guarantee satisfaction because we have confidence in our products, confidence cultivated by the science behind our antibodies: we make them using as much of the native protein as possible, and purifying them using affinity purification with the original antigen. We carry out antibody production over a 102-day period, which allows for better antigen fitting to MHC molecules and affinity maturation in the host. This approach results in higher affinity antibodies with greater sensitivity, which you can use in any application and in multiple species.
You can only buy Proteintech antibodies directly from Proteintech or via one of its approved distributors — when you receive your antibody and see the Proteintech logo on the vial, know that you hold something that is truly unique.