This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Proteintech Group
product type :
antibody
product name :
PINK1
catalog :
23274-1-AP
quantity :
150UL
price :
299 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, proximity ligation assay
citations: 24
Published Application/Species/Sample/DilutionReference
  • proximity ligation assay; human; fig 2
  • western blot; human; fig 1
Scott T, Wicker C, Suganya R, Dhar B, Pittman T, Horbinski C, et al. Polyubiquitination of apurinic/apyrimidinic endonuclease 1 by Parkin. Mol Carcinog. 2017;56:325-336 pubmed publisher
Zhou J, Wang Z, He Y, Luo X, Zhang W, Yu L, et al. Qiliqiangxin reduced cardiomyocytes apotosis and improved heart function in infarcted heart through Pink1/Parkin -mediated mitochondrial autophagy. BMC Complement Med Ther. 2020;20:203 pubmed publisher
Jia X, Qiu T, Yao X, Jiang L, Wang N, Wei S, et al. Arsenic induces hepatic insulin resistance via mtROS-NLRP3 inflammasome pathway. J Hazard Mater. 2020;399:123034 pubmed publisher
Dan X, Babbar M, Moore A, Wechter N, Tian J, Mohanty J, et al. DNA damage invokes mitophagy through a pathway involving Spata18. Nucleic Acids Res. 2020;48:6611-6623 pubmed publisher
Tian Y, Guo H, Miao X, Xu J, Yang R, Zhao L, et al. Nestin protects podocyte from injury in lupus nephritis by mitophagy and oxidative stress. Cell Death Dis. 2020;11:319 pubmed publisher
Sun Y, Lu F, Yu X, Wang B, Chen J, Lu F, et al. Exogenous H2S Promoted USP8 Sulfhydration to Regulate Mitophagy in the Hearts of db/db Mice. Aging Dis. 2020;11:269-285 pubmed publisher
Zhang Z, Chen Z, Liu R, Liang Q, Peng Z, Yin S, et al. Bcl-2 Proteins Regulate Mitophagy in Lipopolysaccharide-Induced Acute Lung Injury via PINK1/Parkin Signaling Pathway. Oxid Med Cell Longev. 2020;2020:6579696 pubmed publisher
Zhao N, Yan Q, Xia J, Zhang X, Li B, Yin L, et al. Treadmill Exercise Attenuates Aβ-Induced Mitochondrial Dysfunction and Enhances Mitophagy Activity in APP/PS1 Transgenic Mice. Neurochem Res. 2020;45:1202-1214 pubmed publisher
Zhao W, Zhang W, Ma H, Yang M. NIPA2 regulates osteoblast function by modulating mitophagy in type 2 diabetes osteoporosis. Sci Rep. 2020;10:3078 pubmed publisher
Liu C, Peng Z, Li P, Fu H, Feng J, Zhang Y, et al. lncRNA RMST Suppressed GBM Cell Mitophagy through Enhancing FUS SUMOylation. Mol Ther Nucleic Acids. 2020;19:1198-1208 pubmed publisher
Wang Y, Yang Y, Zuo R, Wu J, Zhang C, Li C, et al. FOXO3 protects nucleus pulposus cells against apoptosis under nutrient deficiency via autophagy. Biochem Biophys Res Commun. 2020;524:756-763 pubmed publisher
Li C, Zhou J, Liu Z, Zhou J, Yao W, Tao J, et al. FSH prevents porcine granulosa cells from hypoxia-induced apoptosis via activating mitophagy through the HIF-1α-PINK1-Parkin pathway. FASEB J. 2020;34:3631-3645 pubmed publisher
Xia B, Yu J, He T, Liu X, Su J, Wang M, et al. Lactobacillus johnsonii L531 ameliorates enteritis via elimination of damaged mitochondria and suppression of SQSTM1-dependent mitophagy in a Salmonella infantis model of piglet diarrhea. FASEB J. 2020;34:2821-2839 pubmed publisher
Liang C, Gao Y, He Y, Han Y, Manthari R, Tikka C, et al. Fluoride induced mitochondrial impairment and PINK1-mediated mitophagy in Leydig cells of mice: In vivo and in vitro studies. Environ Pollut. 2019;:113438 pubmed publisher
Yu X, Hao M, Liu Y, Ma X, Lin W, Xu Q, et al. Liraglutide ameliorates non-alcoholic steatohepatitis by inhibiting NLRP3 inflammasome and pyroptosis activation via mitophagy. Eur J Pharmacol. 2019;864:172715 pubmed publisher
Zhao C, He R, Shen M, Zhu F, Wang M, Liu Y, et al. PINK1/Parkin-Mediated Mitophagy Regulation by Reactive Oxygen Species Alleviates Rocaglamide A-Induced Apoptosis in Pancreatic Cancer Cells. Front Pharmacol. 2019;10:968 pubmed publisher
Unno R, Kawabata T, Taguchi K, Sugino T, Hamamoto S, Ando R, et al. Deregulated MTOR (mechanistic target of rapamycin kinase) is responsible for autophagy defects exacerbating kidney stone development. Autophagy. 2019;:1-15 pubmed publisher
Espinoza Derout J, Shao X, Bankole E, Hasan K, Mtume N, Liu Y, et al. Hepatic DNA Damage Induced by Electronic Cigarette Exposure Is Associated With the Modulation of NAD+/PARP1/SIRT1 Axis. Front Endocrinol (Lausanne). 2019;10:320 pubmed publisher
Yin F, Yan J, Zhao Y, Guo K, Zhang Z, Li A, et al. Bone marrow mesenchymal stem cells repair Cr (VI)- injured kidney by regulating mitochondria-mediated apoptosis and mitophagy mediated via the MAPK signaling pathway. Ecotoxicol Environ Saf. 2019;176:234-241 pubmed publisher
Sun D, Song C, Xu Y, Wang R, Liu W, Liu Z, et al. Involvement of PINK1/Parkin-mediated mitophagy in paraquat- induced apoptosis in human lung epithelial-like A549 cells. Toxicol In Vitro. 2018;53:148-159 pubmed publisher
Fu T, Xu Z, Liu L, Guo Q, Wu H, Liang X, et al. Mitophagy Directs Muscle-Adipose Crosstalk to Alleviate Dietary Obesity. Cell Rep. 2018;23:1357-1372 pubmed publisher
Xiao Y, Zhou Y, Lu Y, Zhou K, Cai W. PHB2 interacts with LC3 and SQSTM1 is required for bile acids-induced mitophagy in cholestatic liver. Cell Death Dis. 2018;9:160 pubmed publisher
Kravic B, Harbauer A, Romanello V, Simeone L, Vögtle F, Kaiser T, et al. In mammalian skeletal muscle, phosphorylation of TOMM22 by protein kinase CSNK2/CK2 controls mitophagy. Autophagy. 2018;14:311-335 pubmed publisher
Hu D, Cao S, Zhang G, Xiao Y, Liu S, Shang Y. Florfenicol-induced Mitochondrial Dysfunction Suppresses Cell Proliferation and Autophagy in Fibroblasts. Sci Rep. 2017;7:13554 pubmed publisher
product information
CatalogNo :
23274-1-AP
AntigenName :
PINK1
Package :
150UL
Price :
299 USD
Exsists20ul :
20ul trial size available
FullName :
PTEN induced putative kinase 1
Immunogen :
Fusion Protein
Species :
human, mouse, rat, swine
Host :
Rabbit
IsConjugated :
Unconjugated
AntigenSpecies :
human
Application :
WB, IHC, IF, ELISA
Clonlity :
Polyclonal
IsoType :
IgG
Synonyms :
BRPK, PARK6, PINK1, PTEN induced putative kinase 1
PrimaryOrSecondary :
Primary
AntibodyBuffer :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
GenBankNo :
BC028215
Category :
Binding Proteins;Cytoskeleton/Scaffold Proteins;Membrane Proteins;
PurifyMethod :
Antigen Affinity purified
NewAb :
False
IsSellable :
True
Feature :
siRNA
AppTiter :
IF 1:50 ; IHC 1:200 ; WB 1:600 ;
company information
Proteintech Group
2201 W. Campbell Park Dr. STE12
Chicago, IL 60612
Proteintech@ptglab.com
https://www.ptglab.com
1-312-455-8498
headquarters: USA
At Proteintech, we produce every single antibody we sell; we do not rely on or supply to any other antibody providers: our products are unique and we are 100% accountable for each one. We realize this accountability by validating in-house, providing extensive technical support and guaranteeing your success: in addition to helping you troubleshoot your experiment, we will offer you a full cash refund if you are in any way dissatisfied. We can guarantee satisfaction because we have confidence in our products, confidence cultivated by the science behind our antibodies: we make them using as much of the native protein as possible, and purifying them using affinity purification with the original antigen. We carry out antibody production over a 102-day period, which allows for better antigen fitting to MHC molecules and affinity maturation in the host. This approach results in higher affinity antibodies with greater sensitivity, which you can use in any application and in multiple species.
You can only buy Proteintech antibodies directly from Proteintech or via one of its approved distributors — when you receive your antibody and see the Proteintech logo on the vial, know that you hold something that is truly unique.