Phospho-TDP43 (Ser409/410) | Proteintech Group 22309-1-AP product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Proteintech Group

product type :

antibody

product name :

Phospho-TDP43 (Ser409/410)

catalog :

22309-1-AP

quantity :

100UL

price :

299 USD

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

antigen modification :

phosphorylated

reactivity :

human

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry

citations: 24

Published Application/Species/Sample/Dilution	Reference
western blot; human; 1:1000; fig 1a	Smethurst P, Newcombe J, Troakes C, Simone R, Chen Y, Patani R, et al. In vitro prion-like behaviour of TDP-43 in ALS. Neurobiol Dis. 2016;96:236-247 pubmed publisher
western blot; human; fig 3	Alquezar C, Salado I, de la Encarnación A, Perez D, Moreno F, Gil C, et al. Targeting TDP-43 phosphorylation by Casein Kinase-1? inhibitors: a novel strategy for the treatment of frontotemporal dementia. Mol Neurodegener. 2016;11:36 pubmed publisher
	Termsarasab P, Thammongkolchai T, Gao J, Wang L, Liang J, Wang X. Cytoplasmic mislocalization and mitochondrial colocalization of TDP-43 are common features between normal aged and young mice. Exp Biol Med (Maywood). 2020;:1535370220914253 pubmed publisher
	Martínez González L, Rodríguez Cueto C, Cabezudo D, Bartolomé F, Andrés Benito P, Ferrer I, et al. Motor neuron preservation and decrease of in vivo TDP-43 phosphorylation by protein CK-1δ kinase inhibitor treatment. Sci Rep. 2020;10:4449 pubmed publisher
	Huang S, Wu L, Lee M, Chang C, Cheng W, Fang Y, et al. A robust TDP-43 knock-in mouse model of ALS. Acta Neuropathol Commun. 2020;8:3 pubmed publisher
	Gregory J, Livesey M, McDade K, Selvaraj B, Barton S, Chandran S, et al. Dysregulation of AMPA receptor subunit expression in sporadic ALS post-mortem brain. J Pathol. 2020;250:67-78 pubmed publisher
	Hideshima M, Beck G, Yamadera M, Motoyama Y, Ikenaka K, Kakuda K, et al. A clinicopathological study of ALS with L126S mutation in the SOD1 gene presenting with isolated inferior olivary hypertrophy. Neuropathology. 2019;: pubmed publisher
	Sacino A, Prokop S, Walsh M, Adamson J, Subramony S, Krans A, et al. Fragile X-associated tremor ataxia syndrome with co-occurrent progressive supranuclear palsy-like neuropathology. Acta Neuropathol Commun. 2019;7:158 pubmed publisher
	Ng J, Hanspal M, Matharu N, Barros T, Esbjörner E, Wilson M, et al. Using Tetracysteine-Tagged TDP-43 with a Biarsenical Dye To Monitor Real-Time Trafficking in a Cell Model of Amyotrophic Lateral Sclerosis. Biochemistry. 2019;58:4086-4095 pubmed publisher
	Gregory J, McDade K, Bak T, Pal S, Chandran S, Smith C, et al. Executive, language and fluency dysfunction are markers of localised TDP-43 cerebral pathology in non-demented ALS. J Neurol Neurosurg Psychiatry. 2019;: pubmed publisher
	Gregory J, Elliott E, McDade K, Bak T, Pal S, Chandran S, et al. Neuronal clusterin expression is associated with cognitive protection in amyotrophic lateral sclerosis. Neuropathol Appl Neurobiol. 2019;: pubmed publisher
	Regalado Reyes M, Furcila D, Hernandez F, Avila J, DeFelipe J, León Espinosa G. Phospho-Tau Changes in the Human CA1 During Alzheimer's Disease Progression. J Alzheimers Dis. 2019;69:277-288 pubmed publisher
	Huntley M, Gao J, Termsarasab P, Wang L, Zeng S, Thammongkolchai T, et al. Association between TDP-43 and mitochondria in inclusion body myositis. Lab Invest. 2019;: pubmed publisher
	Chen Y, Cohen T. Aggregation of the nucleic acid-binding protein TDP-43 occurs via distinct routes that are coordinated with stress granule formation. J Biol Chem. 2019;294:3696-3706 pubmed publisher
	Statland J, Moore D, Wang Y, Walsh M, Mozaffar T, Elman L, et al. Rasagiline for amyotrophic lateral sclerosis: A randomized, controlled trial. Muscle Nerve. 2019;59:201-207 pubmed publisher
	Posa D, Martínez González L, Bartolomé F, Nagaraj S, Porras G, Martinez A, et al. Recapitulation of Pathological TDP-43 Features in Immortalized Lymphocytes from Sporadic ALS Patients. Mol Neurobiol. 2019;56:2424-2432 pubmed publisher
	Cykowski M, Powell S, Appel J, Arumanayagam A, Rivera A, Appel S. Phosphorylated TDP-43 (pTDP-43) aggregates in the axial skeletal muscle of patients with sporadic and familial amyotrophic lateral sclerosis. Acta Neuropathol Commun. 2018;6:28 pubmed publisher
	Henstridge C, Sideris D, Carroll E, Rotariu S, Salomonsson S, Tzioras M, et al. Synapse loss in the prefrontal cortex is associated with cognitive decline in amyotrophic lateral sclerosis. Acta Neuropathol. 2018;135:213-226 pubmed publisher
	Wilhite R, Sage J, Bouzid A, Primavera T, Agbas A. Platelet phosphorylated TDP-43: an exploratory study for a peripheral surrogate biomarker development for Alzheimer's disease. Future Sci OA. 2017;3:FSO238 pubmed publisher
	Cykowski M, Powell S, Peterson L, Appel J, Rivera A, Takei H, et al. Clinical Significance of TDP-43 Neuropathology in Amyotrophic Lateral Sclerosis. J Neuropathol Exp Neurol. 2017;76:402-413 pubmed publisher
	Mackenzie I, Neumann M. Reappraisal of TDP-43 pathology in FTLD-U subtypes. Acta Neuropathol. 2017;134:79-96 pubmed publisher
	King A, Troakes C, Smith B, Nolan M, Curran O, Vance C, et al. ALS-FUS pathology revisited: singleton FUS mutations and an unusual case with both a FUS and TARDBP mutation. Acta Neuropathol Commun. 2015;3:62 pubmed publisher
	Chou C, Alexeeva O, Yamada S, Pribadi A, Zhang Y, Mo B, et al. PABPN1 suppresses TDP-43 toxicity in ALS disease models. Hum Mol Genet. 2015;24:5154-73 pubmed publisher
	Okamoto K, Fujita Y, Hoshino E, Tamura Y, Fukuda T, Hasegawa M, et al. An autopsy case of familial amyotrophic lateral sclerosis with a TARDBP Q343R mutation. Neuropathology. 2015;35:462-8 pubmed publisher

product information

CatalogNo :

22309-1-AP

AntigenName :

Phospho-TDP43 (Ser409/410)

Package :

100UL

Price :

299 USD

Exsists20ul :

20ul trial size available

FullName :

TAR DNA binding protein

Immunogen :

Peptide

Species :

human, mouse

Host :

Rabbit

IsConjugated :

Unconjugated

AntigenSpecies :

human

Application :

WB, IHC, IF, ELISA

Clonlity :

Polyclonal

IsoType :

IgG

Synonyms :

phospho TDP43, phospho(409/410)-TDP43, Phospho-TDP43 (Ser409/410), TARDBP, TDP43

PrimaryOrSecondary :

Primary

AntibodyBuffer :

PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

GenBankNo :

NM_007375

Category :

Binding Proteins;Cytoskeleton/Scaffold Proteins;Metabolism;Neurology;

PurifyMethod :

Antigen affinity purification

NewAb :

False

IsSellable :

True

AppTiter :

WB 1:600 ;