This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Proteintech Group
product type :
antibody
product name :
N-cadherin
catalog :
22018-1-AP
quantity :
150UL
price :
299 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section
citations: 234
Published Application/Species/Sample/DilutionReference
  • western blot; human; loading ...; fig 2e
Yu W, Hua Y, Qiu H, Hao J, Zou K, Li Z, et al. PD-L1 promotes tumor growth and progression by activating WIP and β-catenin signaling pathways and predicts poor prognosis in lung cancer. Cell Death Dis. 2020;11:506 pubmed publisher
  • western blot; human; loading ...; fig 5f
Yin L, Li W, Xu A, Shi H, Wang K, Yang H, et al. SH3BGRL2 inhibits growth and metastasis in clear cell renal cell carcinoma via activating hippo/TEAD1-Twist1 pathway. EBioMedicine. 2020;51:102596 pubmed publisher
  • western blot; human; loading ...; fig 3c
Liu X, Ma F, Liu C, Zhu K, Li W, Xu Y, et al. UBE2O promotes the proliferation, EMT and stemness properties of breast cancer cells through the UBE2O/AMPKα2/mTORC1-MYC positive feedback loop. Cell Death Dis. 2020;11:10 pubmed publisher
  • western blot; human; loading ...; fig 2o, 2q
Zhou Q, Wu X, Wang X, Yu Z, Pan T, Li Z, et al. The reciprocal interaction between tumor cells and activated fibroblasts mediated by TNF-α/IL-33/ST2L signaling promotes gastric cancer metastasis. Oncogene. 2019;: pubmed publisher
  • western blot; human; loading ...; fig 2c
Xie C, Zhu J, Jiang Y, Chen J, Wang X, Geng S, et al. Sulforaphane Inhibits the Acquisition of Tobacco Smoke-Induced Lung Cancer Stem Cell-Like Properties via the IL-6/ΔNp63α/Notch Axis. Theranostics. 2019;9:4827-4840 pubmed publisher
  • western blot; human; loading ...; fig 2e
Wu D, Zhang T, Liu Y, Deng S, Han R, Liu T, et al. The PAX6-ZEB2 axis promotes metastasis and cisplatin resistance in non-small cell lung cancer through PI3K/AKT signaling. Cell Death Dis. 2019;10:349 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; loading ...; fig 6a
  • western blot; mouse; loading ...; fig 6f
Xie C, Zhu J, Wang X, Chen J, Geng S, Wu J, et al. Tobacco smoke induced hepatic cancer stem cell-like properties through IL-33/p38 pathway. J Exp Clin Cancer Res. 2019;38:39 pubmed publisher
Cui Y, Song Y, Yan S, Cao M, Huang J, Jia D, et al. CUEDC1 inhibits epithelial-mesenchymal transition via the TβRI/Smad signaling pathway and suppresses tumor progression in non-small cell lung cancer. Aging (Albany NY). 2020;12:20047-20068 pubmed publisher
Song K, Jiang Y, Zhao Y, Xie Y, Zhou J, Yu W, et al. Members of the miR-30 family inhibit the epithelial-to-mesenchymal transition of non-small-cell lung cancer cells by suppressing XB130 expression levels. Oncol Lett. 2020;20:68 pubmed publisher
Feng D, Liu M, Liu Y, Zhao X, Sun H, Zheng X, et al. Micheliolide suppresses the viability, migration and invasion of U251MG cells via the NF-κB signaling pathway. Oncol Lett. 2020;20:67 pubmed publisher
Zhou L, Sheng W, Jia C, Shi X, Cao R, Wang G, et al. Musashi2 promotes the progression of pancreatic cancer through a novel ISYNA1-p21/ZEB-1 pathway. J Cell Mol Med. 2020;: pubmed publisher
Guo X, Dai X, Liu J, Cheng A, Qin C, Wang Z. Circular RNA circREPS2 Acts as a Sponge of miR-558 to Suppress Gastric Cancer Progression by Regulating RUNX3/β-catenin Signaling. Mol Ther Nucleic Acids. 2020;21:577-591 pubmed publisher
Lin Y, Jin H, Wu X, Jian Z, Zou X, Huang J, et al. The cross-talk between DDR1 and STAT3 promotes the development of hepatocellular carcinoma. Aging (Albany NY). 2020;12:14391-14405 pubmed publisher
Wang Q, Cheng S, Chen J. HBx mediated Increase of SIRT1 Contributes to HBV-related Hepatocellular Carcinoma Tumorigenesis. Int J Med Sci. 2020;17:1783-1794 pubmed publisher
Sun T, Bi F, Liu Z, Yang Q. SLC7A2 serves as a potential biomarker and therapeutic target for ovarian cancer. Aging (Albany NY). 2020;12:13281-13296 pubmed publisher
Zhang X, Du L, Han J, Li X, Wang H, Zheng G, et al. Novel long non-coding RNA LINC02323 promotes epithelial-mesenchymal transition and metastasis via sponging miR-1343-3p in lung adenocarcinoma. Thorac Cancer. 2020;: pubmed publisher
Chen S, Luo Y, Cui L, Yang Q. miR-96-5p regulated TGF-β/SMAD signaling pathway and suppressed endometrial cell viability and migration via targeting TGFBR1. Cell Cycle. 2020;19:1740-1753 pubmed publisher
Jin M, Gao D, Wang R, Sik A, Liu K. Possible involvement of TGF‑β‑SMAD‑mediated epithelial‑mesenchymal transition in pro‑metastatic property of PAX6. Oncol Rep. 2020;44:555-564 pubmed publisher
Huang Z, Yu P, Tang J. Characterization of Triple-Negative Breast Cancer MDA-MB-231 Cell Spheroid Model. Onco Targets Ther. 2020;13:5395-5405 pubmed publisher
Ye Y, Zhao L, Li Q, Xi C, Li Y, Li Z. circ_0007385 served as competing endogenous RNA for miR-519d-3p to suppress malignant behaviors and cisplatin resistance of non-small cell lung cancer cells. Thorac Cancer. 2020;: pubmed publisher
Liu D, Zhang H, Cui M, Chen C, Feng Y. Hsa-miR-425-5p promotes tumor growth and metastasis by activating the CTNND1-mediated β-catenin pathway and EMT in colorectal cancer. Cell Cycle. 2020;19:1917-1927 pubmed publisher
Zhang X, Pan J, Wang G, Li H, Wang J, Jiang X, et al. Effect of STAT3 mediated epigenetic regulation in pre-eclampsia: an analysis of trial data. Eur Rev Med Pharmacol Sci. 2020;24:5843-5855 pubmed publisher
Liu J, Shangguan Y, Sun J, Cong W, Xie Y. BAIAP2L2 promotes the progression of gastric cancer via AKT/mTOR and Wnt3a/β-catenin signaling pathways. Biomed Pharmacother. 2020;129:110414 pubmed publisher
Chen J, Yang H, Zhou H, Peng R, Niu Z, Kang C. PRR11 and SKA2 promote the proliferation, migration and invasion of esophageal carcinoma cells. Oncol Lett. 2020;20:639-646 pubmed publisher
Sun G, Zhou H, Chen K, Zeng J, Zhang Y, Yan L, et al. HnRNP A1 - mediated alternative splicing of CCDC50 contributes to cancer progression of clear cell renal cell carcinoma via ZNF395. J Exp Clin Cancer Res. 2020;39:116 pubmed publisher
Peng S, Sun Y, Luo Y, Ma S, Sun W, Tang G, et al. MFP-FePt-GO Nanocomposites Promote Radiosensitivity of Non-Small Cell Lung Cancer Via Activating Mitochondrial-Mediated Apoptosis and Impairing DNA Damage Repair. Int J Biol Sci. 2020;16:2145-2158 pubmed publisher
Dong P, Fu H, Chen L, Zhang S, Zhang X, Li H, et al. PCNP promotes ovarian cancer progression by accelerating β-catenin nuclear accumulation and triggering EMT transition. J Cell Mol Med. 2020;: pubmed publisher
Song Y, Yuan H, Wang J, Wu Y, Xiao Y, Mao S. KLHL22 Regulates the EMT and Proliferation in Colorectal Cancer Cells in Part via the Wnt/β-Catenin Signaling Pathway. Cancer Manag Res. 2020;12:3981-3993 pubmed publisher
Zhang X, Han J, Feng L, Zhi L, Jiang D, Yu B, et al. DUOX2 promotes the progression of colorectal cancer cells by regulating the AKT pathway and interacting with RPL3. Carcinogenesis. 2020;: pubmed publisher
Fan L, Lei H, Zhang S, Peng Y, Fu C, Shu G, et al. Non-canonical signaling pathway of SNAI2 induces EMT in ovarian cancer cells by suppressing miR-222-3p transcription and upregulating PDCD10. Theranostics. 2020;10:5895-5913 pubmed publisher
Wang W, Chen H, Gao W, Wang S, Wu K, Lu C, et al. Girdin interaction with vimentin induces EMT and promotes the growth and metastasis of pancreatic ductal adenocarcinoma. Oncol Rep. 2020;44:637-649 pubmed publisher
Wu D, Liu T, Deng S, Han R, Zhang T, Li J, et al. Alpha-1 Antitrypsin Induces Epithelial-to-Mesenchymal Transition, Endothelial-to-Mesenchymal Transition, and Drug Resistance in Lung Cancer Cells. Onco Targets Ther. 2020;13:3751-3763 pubmed publisher
Li J, Wu D, Han R, Yu Y, Deng S, Liu T, et al. Low-Dose Radiation Promotes Invasion and Migration of A549 Cells by Activating the CXCL1/NF-κB Signaling Pathway. Onco Targets Ther. 2020;13:3619-3629 pubmed publisher
Li Q, Wang T, Huang S, Zuo Q, Jiang Z, Yang N, et al. LncRNA MALAT1 affects the migration and invasion of trophoblast cells by regulating FOS expression in early-onset preeclampsia. Pregnancy Hypertens. 2020;21:50-57 pubmed publisher
Ma J, Qi J, Li S, Zhang C, Wang H, Shao L, et al. Desloratadine, a Novel Antigrowth Reagent for Bladder Cancer. Technol Cancer Res Treat. 2020;19:1533033820926591 pubmed publisher
Zhong Y, Cao L, Ma H, Wang Q, Wei P, Yang J, et al. Lin28A Regulates Stem-like Properties of Ovarian Cancer Cells by Enriching RAN and HSBP1 mRNA and Up-regulating its Protein Expression. Int J Biol Sci. 2020;16:1941-1953 pubmed publisher
Ma Z, Lou S, Jiang Z. PHLDA2 regulates EMT and autophagy in colorectal cancer via the PI3K/AKT signaling pathway. Aging (Albany NY). 2020;12:7985-8000 pubmed publisher
Wang S, Wu D, Xu Y, Cao Y, Wang J, Zhang Y, et al. Downregulated placental expression of linc00468 contributes to trophoblast dysfunction by inducing epithelial-mesenchymal transition. Ann Transl Med. 2020;8:333 pubmed publisher
Luo Y, Wang D, Chen S, Yang Q. The role of miR-34c-5p/Notch in epithelial-mesenchymal transition (EMT) in endometriosis. Cell Signal. 2020;72:109666 pubmed publisher
Han B, Ge Y, Cui J, Liu B. Down-regulation of lncRNA DNAJC3-AS1 inhibits colon cancer via regulating miR-214-3p/LIVIN axis. Bioengineered. 2020;11:524-535 pubmed publisher
Gan D, Yue S, Jiang Y, Zhang D, Shi H, Qian H, et al. Nucleus-located PDK1 regulates growth, invasion and migration of breast cancer cells. Life Sci. 2020;253:117722 pubmed publisher
Ge W, Chen Q, Meng L, Huang X, Shi G, Zong Q, et al. The YY1/miR-548t-5p/CXCL11 signaling axis regulates cell proliferation and metastasis in human pancreatic cancer. Cell Death Dis. 2020;11:294 pubmed publisher
Jiang F, Chen Y, Ren S, Li Z, Sun K, Xing Y, et al. Cyclovirobuxine D inhibits colorectal cancer tumorigenesis via the CTHRC1‑AKT/ERK‑Snail signaling pathway. Int J Oncol. 2020;57:183-196 pubmed publisher
Huang R, Wang S, Wang N, Zheng Y, Zhou J, Yang B, et al. CCL5 derived from tumor-associated macrophages promotes prostate cancer stem cells and metastasis via activating β-catenin/STAT3 signaling. Cell Death Dis. 2020;11:234 pubmed publisher
Wu Q, Zhao M, Huang G, Zheng Z, Chen Y, Zeng W, et al. Fibroblast Activation Protein (FAP) Overexpression Induces Epithelial-Mesenchymal Transition (EMT) in Oral Squamous Cell Carcinoma by Down-Regulating Dipeptidyl Peptidase 9 (DPP9). Onco Targets Ther. 2020;13:2599-2611 pubmed publisher
Meng F, Liu X, Lin C, Xu L, Liu J, Zhang P, et al. SMYD2 suppresses APC2 expression to activate the Wnt/β-catenin pathway and promotes epithelial-mesenchymal transition in colorectal cancer. Am J Cancer Res. 2020;10:997-1011 pubmed
Yang Z, Chen Y, Wei X, Wu D, Min Z, Quan Y. Upregulated NTF4 in colorectal cancer promotes tumor development via regulating autophagy. Int J Oncol. 2020;56:1442-1454 pubmed publisher
Zhong M, Zhu M, Liu Y, Lin Y, Wang L, Ye Y, et al. TNFAIP8 promotes the migration of clear cell renal cell carcinoma by regulating the EMT. J Cancer. 2020;11:3061-3071 pubmed publisher
Cao Y, Han Q, Li J, Jia Y, Zhang R, Shi H. P4HA2 contributes to cervical cancer progression via inducing epithelial-mesenchymal transition. J Cancer. 2020;11:2788-2799 pubmed publisher
Du J, Li J, Gao M, Guan Q, Liu T, Wu Y, et al. MAY, a novel tubulin inhibitor, induces cell apoptosis in A549 and A549/Taxol cells and inhibits epithelial-mesenchymal transition in A549/Taxol cells. Chem Biol Interact. 2020;323:109074 pubmed publisher
Yang Y, Liu X, Cheng L, Li L, Wei Z, Wang Z, et al. Tumor Suppressor microRNA-138 Suppresses Low-Grade Glioma Development and Metastasis via Regulating IGF2BP2. Onco Targets Ther. 2020;13:2247-2260 pubmed publisher
Lin L, Wang D, Qu S, Zhao H, Lin Y. miR-370-3p Alleviates Ulcerative Colitis-Related Colorectal Cancer in Mice Through Inhibiting the Inflammatory Response and Epithelial-Mesenchymal Transition. Drug Des Devel Ther. 2020;14:1127-1141 pubmed publisher
Xu B, Wang C, Wang Y, Chen S, Wu J, Zhu W, et al. miR-143 inhibits renal cell carcinoma cells metastatic potential by suppressing ABL2. Kaohsiung J Med Sci. 2020;: pubmed publisher
Cui X, Zhang H, Cao A, Cao L, Hu X. Cytokine TNF-α promotes invasion and metastasis of gastric cancer by down-regulating Pentraxin3. J Cancer. 2020;11:1800-1807 pubmed publisher
Pan B, Liu L, Hu X, Sun X, Zhu Y, Zhang T, et al. Promotion of esophageal adenocarcinoma metastasis via Wnt/ß-catenin signal pathway by sorting nexins 3. J Gastroenterol Hepatol. 2020;: pubmed publisher
Xiao Y, Qing J, Li B, Chen L, Nong S, Yang W, et al. TIM-3 Participates in the Invasion and Metastasis of Nasopharyngeal Carcinoma via SMAD7/SMAD2/SNAIL1 Axis-Mediated Epithelial-Mesenchymal Transition. Onco Targets Ther. 2020;13:1993-2006 pubmed publisher
Wang Q, Yang G, Jiang Y, Luo M, Li C, Zhao Y, et al. XB130, regulated by miR-203, miR-219, and miR-4782-3p, mediates the proliferation and metastasis of non-small-cell lung cancer cells. Mol Carcinog. 2020;59:557-568 pubmed publisher
Papiernik D, Urbaniak A, Kłopotowska D, Nasulewicz Goldeman A, Ekiert M, Nowak M, et al. Retinol-Binding Protein 4 Accelerates Metastatic Spread and Increases Impairment of Blood Flow in Mouse Mammary Gland Tumors. Cancers (Basel). 2020;12: pubmed publisher
Wang D, Tang J, Zhang G, Chang X. ARHGEF10L expression regulates cell proliferation and migration in gastric tumorigenesis. Biosci Biotechnol Biochem. 2020;84:1362-1372 pubmed publisher
Ma C, Huang S, Xu L, Tian L, Yang Y, Wang J. Transcription co-activator P300 activates Elk1-aPKC-ι signaling mediated epithelial-to-mesenchymal transition and malignancy in hepatocellular carcinoma. Oncogenesis. 2020;9:32 pubmed publisher
Liu F, Shang Y. Sirtuin 6 attenuates epithelial-mesenchymal transition by suppressing the TGF-β1/Smad3 pathway and c-Jun in asthma models. Int Immunopharmacol. 2020;82:106333 pubmed publisher
Pan S, Ren F, Li L, Liu D, Li Y, Wang A, et al. MiR-328-3p inhibits cell proliferation and metastasis in colorectal cancer by targeting Girdin and inhibiting the PI3K/Akt signaling pathway. Exp Cell Res. 2020;390:111939 pubmed publisher
Peng Y, Li F, Zhang P, Wang X, Shen Y, Feng Y, et al. IGF-1 promotes multiple myeloma progression through PI3K/Akt-mediated epithelial-mesenchymal transition. Life Sci. 2020;249:117503 pubmed publisher
Yu Y, Cai L, Wang X, Cheng S, Zhang D, Jian W, et al. BMP8A promotes survival and drug resistance via Nrf2/TRIM24 signaling pathway in clear cell renal cell carcinoma. Cancer Sci. 2020;111:1555-1566 pubmed publisher
Liu Y, Xia L, Dong L, Wang J, Xiao Q, Yu X, et al. CircHIPK3 Promotes Gemcitabine (GEM) Resistance in Pancreatic Cancer Cells by Sponging miR-330-5p and Targets RASSF1. Cancer Manag Res. 2020;12:921-929 pubmed publisher
Sun H, Zhao A, Li M, Dong H, Sun Y, Zhang X, et al. Interaction of calcium binding protein S100A16 with myosin-9 promotes cytoskeleton reorganization in renal tubulointerstitial fibrosis. Cell Death Dis. 2020;11:146 pubmed publisher
Wu K, Li L, Li L, Wang D. Long non-coding RNA HAL suppresses the migration and invasion of serous ovarian cancer by inhibiting EMT signaling pathway. Biosci Rep. 2020;40: pubmed publisher
Li S, Hou X, Wu C, Han L, Li Q, Wang J, et al. MiR-645 promotes invasiveness, metastasis and tumor growth in colorectal cancer by targeting EFNA5. Biomed Pharmacother. 2020;125:109889 pubmed publisher
Zhao X, Ding L, Lu Z, Huang X, Jing Y, Yang Y, et al. Diminished CD68+ Cancer-Associated Fibroblast Subset Induces Regulatory T-Cell (Treg) Infiltration and Predicts Poor Prognosis of Oral Squamous Cell Carcinoma Patients. Am J Pathol. 2020;190:886-899 pubmed publisher
Chen T, Lei S, Zeng Z, Zhang J, Xue Y, Sun Y, et al. Linc00261 inhibits metastasis and the WNT signaling pathway of pancreatic cancer by regulating a miR‑552‑5p/FOXO3 axis. Oncol Rep. 2020;43:930-942 pubmed publisher
Chen Y, Yang Z, Deng B, Wu D, Quan Y, Min Z. Interleukin 1β/1RA axis in colorectal cancer regulates tumor invasion, proliferation and apoptosis via autophagy. Oncol Rep. 2020;43:908-918 pubmed publisher
Chen T, Lei S, Zeng Z, Pan S, Zhang J, Xue Y, et al. MicroRNA‑137 suppresses the proliferation, migration and invasion of cholangiocarcinoma cells by targeting WNT2B. Int J Mol Med. 2020;45:886-896 pubmed publisher
Ying Y, Li J, Xie H, Yan H, Jin K, He L, et al. CCND1, NOP14 and DNMT3B are involved in miR-502-5p-mediated inhibition of cell migration and proliferation in bladder cancer. Cell Prolif. 2020;53:e12751 pubmed publisher
Hu Y, Yan Y, Xu Y, Yang H, Fang L, Liu Y, et al. Expression and clinical significance of WWOX, Elf5, Snail1 and EMT related factors in epithelial ovarian cancer. Oncol Lett. 2020;19:1281-1290 pubmed publisher
Zhang R, Liu J, Zhang W, Hua L, Qian L, Zhou S. EphA5 knockdown enhances the invasion and migration ability of esophageal squamous cell carcinoma via epithelial-mesenchymal transition through activating Wnt/β-catenin pathway. Cancer Cell Int. 2020;20:20 pubmed publisher
Chen X, Jia Y, Zhang Y, Zhou D, Sun H, Ma X. α5-nAChR contributes to epithelial-mesenchymal transition and metastasis by regulating Jab1/Csn5 signalling in lung cancer. J Cell Mol Med. 2020;24:2497-2506 pubmed publisher
Jiang W, Yan Y, Chen M, Luo G, Hao J, Pan J, et al. Aspirin enhances the sensitivity of colon cancer cells to cisplatin by abrogating the binding of NF-κB to the COX-2 promoter. Aging (Albany NY). 2020;12:611-627 pubmed publisher
Zhu J, Li B, Xu M, Liu R, Xia T, Zhang Z, et al. Graphene Oxide Promotes Cancer Metastasis through Associating with Plasma Membrane To Promote TGF-β Signaling-Dependent Epithelial-Mesenchymal Transition. ACS Nano. 2020;14:818-827 pubmed publisher
Wang Y, Liu G, Sun S, Qin J. miR-1294 alleviates epithelial-mesenchymal transition by repressing FOXK1 in gastric cancer. Genes Genomics. 2020;42:217-224 pubmed publisher
Zhao C, Yu W, Qi Y, Xu L, Wang Z, Qiang Y, et al. Quantitative proteomic analysis reveals that Luks-PV exerts antitumor activity by regulating the key proteins and metabolic pathways in HepG2 cells. Anticancer Drugs. 2020;31:223-230 pubmed publisher
Liu Y, Chen S, Liu J, Jin Y, Yu S, An R. Telmisartan inhibits oxalate and calcium oxalate crystal-induced epithelial-mesenchymal transformation via PPAR-γ-AKT/STAT3/p38 MAPK-Snail pathway. Life Sci. 2020;241:117108 pubmed publisher
Li F, Zhao F, Li M, Pan M, Shi F, Xu H, et al. Decreasing New York esophageal squamous cell carcinoma 1 expression inhibits multiple myeloma growth and osteolytic lesions. J Cell Physiol. 2020;235:2183-2194 pubmed publisher
Yang S, Liu T, Sun Y, Liang X. The long noncoding RNA LINC00483 promotes lung adenocarcinoma progression by sponging miR-204-3p. Cell Mol Biol Lett. 2019;24:70 pubmed publisher
Cui X, Wang H, Li Y, Chen T, Liu S, Yan Q. Epiregulin promotes trophoblast epithelial-mesenchymal transition through poFUT1 and O-fucosylation by poFUT1 on uPA. Cell Prolif. 2019;:e12745 pubmed publisher
Wu F, Qin Y, Jiang Q, Zhang J, Li F, Li Q, et al. MyoD1 suppresses cell migration and invasion by inhibiting FUT4 transcription in human gastric cancer cells. Cancer Gene Ther. 2019;: pubmed publisher
Wu L, Zhou Z, Han S, Chen J, Liu Z, Zhang X, et al. PLAGL2 promotes epithelial-mesenchymal transition and mediates colorectal cancer metastasis via β-catenin-dependent regulation of ZEB1. Br J Cancer. 2019;: pubmed publisher
Li H, Cui X, Hu Q, Chen X, Zhou P. CLK3 Is A Direct Target Of miR-144 And Contributes To Aggressive Progression In Hepatocellular Carcinoma. Onco Targets Ther. 2019;12:9201-9213 pubmed publisher
Tong R, Zhang J, Wang C, Li Q, Wang L, Ju M. Inhibition of miR-574-5p suppresses cell growth and metastasis and enhances chemosensitivity by targeting RNA binding protein QKI in cervical cancer cells. Naunyn Schmiedebergs Arch Pharmacol. 2019;: pubmed publisher
Wu Y, Lin S, Din Z, Su J, Liu C. Sinulariolide Inhibits Gastric Cancer Cell Migration and Invasion through Downregulation of the EMT Process and Suppression of FAK/PI3K/AKT/mTOR and MAPKs Signaling Pathways. Mar Drugs. 2019;17: pubmed publisher
Men W, Li W, Li Y, Zhao J, Qu X, Li P, et al. RUFY3 Predicts Poor Prognosis and Promotes Metastasis through Epithelial-mesenchymal Transition in Lung Adenocarcinoma. J Cancer. 2019;10:6278-6285 pubmed publisher
Yan L, Ding B, Liu H, Zhang Y, Zeng J, Hu J, et al. Inhibition of SMYD2 suppresses tumor progression by down-regulating microRNA-125b and attenuates multi-drug resistance in renal cell carcinoma. Theranostics. 2019;9:8377-8391 pubmed publisher
Zhou S, Yang J, Wang M, Zheng D, Liu Y. Endoplasmic reticulum stress regulates epithelial‑mesenchymal transition in human lens epithelial cells. Mol Med Rep. 2019;: pubmed publisher
Sun J, Zhang Y, Li B, Dong Y, Sun C, Zhang F, et al. PITPNA-AS1 abrogates the inhibition of miR-876-5p on WNT5A to facilitate hepatocellular carcinoma progression. Cell Death Dis. 2019;10:844 pubmed publisher
Zhang Q, Zhao X, Zhang C, Wang W, Li F, Liu D, et al. Overexpressed PKMYT1 promotes tumor progression and associates with poor survival in esophageal squamous cell carcinoma. Cancer Manag Res. 2019;11:7813-7824 pubmed publisher
Lin L, Xiao J, Shi L, Chen W, Ge Y, Jiang M, et al. STRA6 exerts oncogenic role in gastric tumorigenesis by acting as a crucial target of miR-873. J Exp Clin Cancer Res. 2019;38:452 pubmed publisher
Lu H, Feng Y, Hu Y, Guo Y, Liu Y, Mao Q, et al. Spondin 2 promotes the proliferation, migration and invasion of gastric cancer cells. J Cell Mol Med. 2019;: pubmed publisher
Jiang Y, Ye R, Yang J, Liu N, Zhang W, Ma L, et al. Protective effects of Salidroside on spermatogenesis in streptozotocin induced type-1 diabetic male mice by inhibiting oxidative stress mediated blood-testis barrier damage. Chem Biol Interact. 2019;315:108869 pubmed publisher
Liu X, Zhao J, Luan X, Li S, Zhai J, Liu J, et al. SPARCL1 impedes trophoblast migration and invasion by down-regulating ERK phosphorylation and AP-1 production and altering EMT-related molecule expression. Placenta. 2019;89:33-41 pubmed publisher
Wen S, Sun L, An R, Zhang W, Xiang L, Li Q, et al. A combination of Citrus reticulata peel and black tea inhibits migration and invasion of liver cancer via PI3K/AKT and MMPs signaling pathway. Mol Biol Rep. 2019;: pubmed publisher
Zong Z, Du Y, Guan X, Chen S, Zhao Y. CircWHSC1 promotes ovarian cancer progression by regulating MUC1 and hTERT through sponging miR-145 and miR-1182. J Exp Clin Cancer Res. 2019;38:437 pubmed publisher
Guo Q, Zhu L, Wang C, Wang S, Nie X, Liu J, et al. SERPIND1 Affects the Malignant Biological Behavior of Epithelial Ovarian Cancer via the PI3K/AKT Pathway: A Mechanistic Study. Front Oncol. 2019;9:954 pubmed publisher
Gu Y, Li C, Xiao L, Li J, Pei H, Xu D, et al. High expression of long non-coding RNA NNT-AS1 facilitates progression of cholangiocarcinoma through promoting epithelial-mesenchymal transition. Am J Transl Res. 2019;11:5438-5456 pubmed
Chen S, Wang J, Wang L, Peng H, Xiao L, Li C, et al. Silencing TTK expression inhibits the proliferation and progression of prostate cancer. Exp Cell Res. 2019;385:111669 pubmed publisher
Jiang Y, Yang J, Ye R, Liu N, Zhang W, Ma L, et al. Protective effects of betaine on diabetic induced disruption of the male mice blood-testis barrier by regulating oxidative stress-mediated p38 MAPK pathways. Biomed Pharmacother. 2019;120:109474 pubmed publisher
Qu Y, Zhang L, Wang J, Chen P, Jia Y, Wang C, et al. Yes-associated protein (YAP) predicts poor prognosis and regulates progression of esophageal squamous cell cancer through epithelial-mesenchymal transition. Exp Ther Med. 2019;18:2993-3001 pubmed publisher
Qu Y, Wen Z, Mi S, Chen P, Wang J, Jia Y, et al. 12-lipoxygenase promotes tumor progress by TGF-β1-mediated epithelial to mesenchymal transition and predicts poor prognosis in esophageal squamous cell carcinoma. Cancer Manag Res. 2019;11:8303-8313 pubmed publisher
Fan X, Zhao Y. miR-451a inhibits cancer growth, epithelial-mesenchymal transition and induces apoptosis in papillary thyroid cancer by targeting PSMB8. J Cell Mol Med. 2019;23:8067-8075 pubmed publisher
Li C, Zheng H, Hou W, Bao H, Xiong J, Che W, et al. Long non-coding RNA linc00645 promotes TGF-β-induced epithelial-mesenchymal transition by regulating miR-205-3p-ZEB1 axis in glioma. Cell Death Dis. 2019;10:717 pubmed publisher
Gao L, Zheng M, Guo Q, Nie X, Li X, Hao Y, et al. Downregulation of Rab23 inhibits proliferation, invasion, and metastasis of human ovarian cancer. Int J Biochem Cell Biol. 2019;116:105617 pubmed publisher
Zheng Y, Liu P, Wang N, Wang S, Yang B, Li M, et al. Betulinic Acid Suppresses Breast Cancer Metastasis by Targeting GRP78-Mediated Glycolysis and ER Stress Apoptotic Pathway. Oxid Med Cell Longev. 2019;2019:8781690 pubmed publisher
Wu D, Deng S, Zhou J, Han R, Liu T, Zhang T, et al. PLEK2 mediates metastasis and vascular invasion via the ubiquitin-dependent degradation of SHIP2 in non-small cell lung cancer. Int J Cancer. 2019;: pubmed publisher
Xu Q, Long Q, Zhu D, Fu D, Zhang B, Han L, et al. Targeting amphiregulin (AREG) derived from senescent stromal cells diminishes cancer resistance and averts programmed cell death 1 ligand (PD-L1)-mediated immunosuppression. Aging Cell. 2019;18:e13027 pubmed publisher
Yao L, Wang S, Wei P, Bao K, Yuan W, Wang X, et al. Huangqi-Fangfeng protects against allergic airway remodeling through inhibiting epithelial-mesenchymal transition process in mice via regulating epithelial derived TGF-β1. Phytomedicine. 2019;64:153076 pubmed publisher
Liu Q, Guan Y, Li Z, Wang Y, Liu Y, Cui R, et al. miR-504 suppresses mesenchymal phenotype of glioblastoma by directly targeting the FZD7-mediated Wnt-β-catenin pathway. J Exp Clin Cancer Res. 2019;38:358 pubmed publisher
Fan J, Wang Q, Zhang Z, Sun L. Curcumin mitigates the epithelial-to-mesenchymal transition in biliary epithelial cells through upregulating CD109 expression. Drug Dev Res. 2019;: pubmed publisher
Li X, Fu Y, Xia X, Zhang X, Xiao K, Zhuang X, et al. Knockdown of SP1/Syncytin1 axis inhibits the proliferation and metastasis through the AKT and ERK1/2 signaling pathways in non-small cell lung cancer. Cancer Med. 2019;: pubmed publisher
Li M, Chen Y, Zhu J, Gao Z, Wang T, Zhou P. Long noncoding RNA CASC15 predicts unfavorable prognosis and exerts oncogenic functions in non-small cell lung cancer. Am J Transl Res. 2019;11:4303-4314 pubmed
Wang L, Zhuang T, Li F, Wei W. Fluorene-9-bisphenol inhibits epithelial-mesenchymal transition of human endometrial cancer Ishikawa cells by repressing TGF-β signaling pathway. Environ Sci Pollut Res Int. 2019;26:27407-27413 pubmed publisher
Sun Y, Li C, Feng J, Li Y, Zhai X, Zhang L, et al. Ferritinophagic Flux Activation in CT26 Cells Contributed to EMT Inhibition Induced by a Novel Iron Chelator, DpdtpA. Oxid Med Cell Longev. 2019;2019:8753413 pubmed publisher
Li X, Huang Y, Guo S, Xie M, Bin X, Shi M, et al. Exogenous regucalcin negatively regulates the progression of cervical adenocarcinoma. Oncol Lett. 2019;18:609-616 pubmed publisher
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product information
CatalogNo :
22018-1-AP
AntigenName :
N-cadherin
Package :
150UL
Price :
299 USD
Exsists20ul :
20ul trial size available
FullName :
cadherin 2, type 1, N-cadherin (neuronal)
Immunogen :
Fusion Protein
Species :
cow, gekko japonicus, human, mouse, rat
Host :
Rabbit
IsConjugated :
Unconjugated
AntigenSpecies :
human
Application :
WB, IP, IHC, IF, FC, ELISA
Clonlity :
Polyclonal
IsoType :
IgG
Synonyms :
Cadherin 2, CD325, CDH2, CDHN, CDw325, N cadherin, NCAD, N-cadherin, Neural cadherin
PrimaryOrSecondary :
Primary
AntibodyBuffer :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
GenBankNo :
BC036470
Category :
Binding Proteins;Cytoskeleton/Scaffold Proteins;Membrane Proteins;Neurology;Signal transduction;
PurifyMethod :
Antigen affinity purification
NewAb :
False
IsSellable :
True
Feature :
siRNA
AppTiter :
FC 1:0 ; IF 1:50 ; IHC 1:2000 ; IP 1:1500 ; WB 1:5000 ;
company information
Proteintech Group
2201 W. Campbell Park Dr. STE12
Chicago, IL 60612
Proteintech@ptglab.com
https://www.ptglab.com
1-312-455-8498
headquarters: USA
At Proteintech, we produce every single antibody we sell; we do not rely on or supply to any other antibody providers: our products are unique and we are 100% accountable for each one. We realize this accountability by validating in-house, providing extensive technical support and guaranteeing your success: in addition to helping you troubleshoot your experiment, we will offer you a full cash refund if you are in any way dissatisfied. We can guarantee satisfaction because we have confidence in our products, confidence cultivated by the science behind our antibodies: we make them using as much of the native protein as possible, and purifying them using affinity purification with the original antigen. We carry out antibody production over a 102-day period, which allows for better antigen fitting to MHC molecules and affinity maturation in the host. This approach results in higher affinity antibodies with greater sensitivity, which you can use in any application and in multiple species.
You can only buy Proteintech antibodies directly from Proteintech or via one of its approved distributors — when you receive your antibody and see the Proteintech logo on the vial, know that you hold something that is truly unique.