This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Proteintech Group
product type :
antibody
product name :
TGF-beta 1
catalog :
21898-1-AP
quantity :
150UL
price :
299 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section
citations: 126
Published Application/Species/Sample/DilutionReference
  • western blot; human; 1:100; loading ...; fig 5c
Wang X, Lu Q, Fei X, Zhao Y, Shi B, Li C, et al. Expression and Prognostic Value of Id-4 in Patients with Esophageal Squamous Cell Carcinoma. Onco Targets Ther. 2020;13:1225-1234 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; loading ...; fig 2a, b
Yang S, Ma C, Wu H, Zhang H, Yuan F, Yang G, et al. Tectorigenin attenuates diabetic nephropathy by improving vascular endothelium dysfunction through activating AdipoR1/2 pathway. Pharmacol Res. 2020;153:104678 pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 1b, 5f
Jiang Z, Tang Y, Song H, Yang M, Li B, Ni C. miRNA‑342 suppresses renal interstitial fibrosis in diabetic nephropathy by targeting SOX6. Int J Mol Med. 2020;45:45-52 pubmed publisher
  • western blot; mouse; loading ...; fig s4d
Chen Z, Sun X, Chen Q, Lan T, Huang K, Xiao H, et al. Connexin32 ameliorates renal fibrosis in diabetic mice by promoting K48-linked Nox4 polyubiquitination and degradation via the inhibition of Smurf1 expression. Br J Pharmacol. 2019;: pubmed publisher
  • western blot; human; loading ...; fig s5
Wang M, Xiong L, Jiang L, Lu Y, Liu F, Song L, et al. miR-4739 mediates pleural fibrosis by targeting bone morphogenetic protein 7. EBioMedicine. 2019;41:670-682 pubmed publisher
Liu J, Yang Q, Xiao K, Dobleman T, Hu S, Xiao G. Obg-like ATPase 1 inhibited oral carcinoma cell metastasis through TGFβ/SMAD2 axis in vitro. BMC Mol Cell Biol. 2020;21:65 pubmed publisher
Li M, Xie L, Li Y, Liu J, Nie G, Yang H. Synergistic effect of Huyang Yangkun Formula and embryonic stem cells on 4-vinylcyclohexene diepoxide induced premature ovarian insufficiency in mice. Chin Med. 2020;15:83 pubmed publisher
Zhao Y, Sun D, Chen Y, Zhan K, Meng Q, Zhang X, et al. Si-Miao-Yong-An Decoction attenuates isoprenaline-induced myocardial fibrosis in AMPK-driven Akt/mTOR and TGF-β/SMAD3 pathways. Biomed Pharmacother. 2020;130:110522 pubmed publisher
Li J, Liu J, Yue W, Xu K, Cai W, Cui F, et al. Andrographolide attenuates epithelial-mesenchymal transition induced by TGF-β1 in alveolar epithelial cells. J Cell Mol Med. 2020;: pubmed publisher
Wu L, Wang Q, Guo F, Ma X, Wang J, Zhao Y, et al. Involvement of miR-27a-3p in diabetic nephropathy via affecting renal fibrosis, mitochondrial dysfunction, and endoplasmic reticulum stress. J Cell Physiol. 2020;: pubmed publisher
Ndibalema A, Kabuye D, Wen S, Li L, Li X, Fan Q. Empagliflozin Protects Against Proximal Renal Tubular Cell Injury Induced by High Glucose via Regulation of Hypoxia-Inducible Factor 1-Alpha. Diabetes Metab Syndr Obes. 2020;13:1953-1967 pubmed publisher
Chen Y, Zhou B, Yu Z, Yuan P, Sun T, Gong J, et al. Baicalein Alleviates Erectile Dysfunction Associated With Streptozotocin-Induced Type I Diabetes by Ameliorating Endothelial Nitric Oxide Synthase Dysfunction, Inhibiting Oxidative Stress and Fibrosis. J Sex Med. 2020;17:1434-1447 pubmed publisher
Lin X, Li Y, Zhang X, Wei Y, Wen S, Lu Z, et al. Tormentic acid inhibits hepatic stellate cells activation via blocking PI3K/Akt/mTOR and NF-κB signalling pathways. Cell Biochem Funct. 2020;: pubmed publisher
Liu X, Mi X, Wang Z, Zhang M, Hou J, Jiang S, et al. Ginsenoside Rg3 promotes regression from hepatic fibrosis through reducing inflammation-mediated autophagy signaling pathway. Cell Death Dis. 2020;11:454 pubmed publisher
Liu J, Chen Y, Cao Z, Guan B, Peng J, Chen Y, et al. Babao Dan inhibits the migration and invasion of gastric cancer cells by suppressing epithelial-mesenchymal transition through the TGF-β/Smad pathway. J Int Med Res. 2020;48:300060520925598 pubmed publisher
Tan X, Li T, Zhu S, Zhong W, Li F, Wang Y. Induction of SPARC on Oxidative Stress, Inflammatory Phenotype Transformation, and Apoptosis of Human Brain Smooth Muscle Cells Via TGF-β1-NOX4 Pathway. J Mol Neurosci. 2020;: pubmed publisher
He J, Chen H, Zhou W, Chen M, Yao Y, Zhang Z, et al. Kidney targeted delivery of asiatic acid using a FITC labeled renal tubular-targeting peptide modified PLGA-PEG system. Int J Pharm. 2020;584:119455 pubmed publisher
Cui Q, Zhang D, Kong D, Tang J, Liao X, Yang Q, et al. Co-transplantation with adipose-derived cells to improve parathyroid transplantation in a mice model. Stem Cell Res Ther. 2020;11:200 pubmed publisher
Huang K, Zhao X. USP9X prevents AGEs-induced upregulation of FN and TGF-β1 through activating Nrf2-ARE pathway in rat glomerular mesangial cells. Exp Cell Res. 2020;393:112100 pubmed publisher
Yang X, Yang R, Chen M, Zhou Q, Zheng Y, Lu C, et al. KGF-2 and FGF-21 poloxamer 407 hydrogel coordinates inflammation and proliferation homeostasis to enhance wound repair of scalded skin in diabetic rats. BMJ Open Diabetes Res Care. 2020;8: pubmed publisher
Wu N, Wu Z, Sun J, Yan M, Wang B, Du X, et al. Small airway remodeling in diabetic and smoking chronic obstructive pulmonary disease patients. Aging (Albany NY). 2020;12:7927-7944 pubmed publisher
Xing M, Fu R, Liu Y, Wang P, Ma P, Zhu C, et al. Human-like collagen promotes the healing of acetic acid-induced gastric ulcers in rats by regulating NOS and growth factors. Food Funct. 2020;11:4123-4137 pubmed publisher
Zhao F, Wu Y, Yang W, Wu D, Wang C, Zhang F. Inhibition of vascular calcification by microRNA-155-5p is accompanied by the inactivation of TGF-β1/Smad2/3 signaling pathway. Acta Histochem. 2020;122:151551 pubmed publisher
Yang X, Li S, Wu Y, Ge F, Chen Y, Xiong Q. The circular RNA CDR1as regulate cell proliferation via TMED2 and TMED10. BMC Cancer. 2020;20:312 pubmed publisher
Xu S, Mao Y, Wu J, Feng J, Li J, Wu L, et al. TGF-β/Smad and JAK/STAT pathways are involved in the anti-fibrotic effects of propylene glycol alginate sodium sulphate on hepatic fibrosis. J Cell Mol Med. 2020;24:5224-5237 pubmed publisher
Zeng Y, Hua Y, Wang W, Zhang H, Xu X. Modulation of SIRT1-mediated signaling cascades in the liver contributes to the amelioration of nonalcoholic steatohepatitis in high fat fed middle-aged LDL receptor knockout mice by dihydromyricetin. Biochem Pharmacol. 2020;175:113927 pubmed publisher
Zong J, Jiang J, Shi P, Liu J, Wang W, Li B, et al. Fatty acid extracts facilitate cutaneous wound healing through activating AKT, ERK, and TGF-β/Smad3 signaling and promoting angiogenesis. Am J Transl Res. 2020;12:478-492 pubmed
Xu Z, Wu Y, Wang F, Li X, Wang P, Li Y, et al. Fibroblast Growth Factor 1 Ameliorates Diabetes-Induced Liver Injury by Reducing Cellular Stress and Restoring Autophagy. Front Pharmacol. 2020;11:52 pubmed publisher
Yao L, Zhou B, You L, Hu H, Xie R. LncRNA MIAT/miR-133a-3p axis regulates atrial fibrillation and atrial fibrillation-induced myocardial fibrosis. Mol Biol Rep. 2020;47:2605-2617 pubmed publisher
Guo Y, Fan Y, Pei X. Fangjihuangqi Decoction inhibits MDA-MB-231 cell invasion in vitro and decreases tumor growth and metastasis in triple-negative breast cancer xenografts tumor zebrafish model. Cancer Med. 2020;9:2564-2578 pubmed publisher
Zhou Z, Ni J, Li J, Huo C, Miao N, Yin F, et al. RIG-I aggravates interstitial fibrosis via c-Myc-mediated fibroblast activation in UUO mice. J Mol Med (Berl). 2020;98:527-540 pubmed publisher
Chen S, Lin C, Chen H, Cheng Y, Cheng H, Imai K. Effect of prednisolone on glyoxalase 1 in an inbred mouse model of aristolochic acid nephropathy using a proteomics method with fluorogenic derivatization-liquid chromatography-tandem mass spectrometry. PLoS ONE. 2020;15:e0227838 pubmed publisher
Ren L, Liu W, Wang C, Yang Y, Huang X, Wang C, et al. The ancient Chinese formula Longdan Xiegan Tang improves antipsychotic-induced hyperprolactinemia by repairing the hypothalamic and pituitary TGF-β1 signaling in rats. J Ethnopharmacol. 2020;254:112572 pubmed publisher
Wang S, Zhang M, Zhang T, Deng J, Xia X, Fang X. microRNA-141 inhibits TGF-β1-induced epithelial-to-mesenchymal transition through inhibition of the TGF-β1/SMAD2 signalling pathway in endometriosis. Arch Gynecol Obstet. 2020;: pubmed publisher
Guan R, Wang J, Cai Z, Li Z, Wang L, Li Y, et al. Hydrogen sulfide attenuates cigarette smoke-induced airway remodeling by upregulating SIRT1 signaling pathway. Redox Biol. 2020;28:101356 pubmed publisher
Shao Q, Jiang C, Xia Y, Zhao M, Zhang Q, Jin B, et al. Dioscin ameliorates peritoneal fibrosis by inhibiting epithelial-to-mesenchymal transition of human peritoneal mesothelial cells via the TLR4/MyD88/NF-κB signaling pathway. Int J Clin Exp Pathol. 2019;12:867-875 pubmed
Zhao W, Fang Q, Wang X, Wang X, Zhang T, Shi B, et al. Chitosan-calcium alginate dressing promotes wound healing: A preliminary study. Wound Repair Regen. 2019;: pubmed publisher
Li Z, Chen D, Jia Y, Feng Y, Wang C, Tong Y, et al. Methane-Rich Saline Counteracts Cholestasis-Induced Liver Damage via Regulating the TLR4/NF-κB/NLRP3 Inflammasome Pathway. Oxid Med Cell Longev. 2019;2019:6565283 pubmed publisher
Liu X, Qu C, Shi S, Ye T, Wang L, Liu S, et al. The Reversal Effect of Sigma-1 Receptor (S1R) Agonist, SA4503, on Atrial Fibrillation After Depression and Its Underlying Mechanism. Front Physiol. 2019;10:1346 pubmed publisher
Yang E, Cai Y, Yao X, Liu J, Wang Q, Jin W, et al. Tissue plasminogen activator disrupts the blood-brain barrier through increasing the inflammatory response mediated by pericytes after cerebral ischemia. Aging (Albany NY). 2019;11:10167-10182 pubmed publisher
Hong W, Zhang G, Lu H, Guo Y, Zheng S, Zhu H, et al. Epithelial and interstitial Notch1 activity contributes to the myofibroblastic phenotype and fibrosis. Cell Commun Signal. 2019;17:145 pubmed publisher
Che H, Wang Y, Li Y, Lv J, Li H, Liu Y, et al. Inhibition of microRNA-150-5p alleviates cardiac inflammation and fibrosis via targeting Smad7 in high glucose-treated cardiac fibroblasts. J Cell Physiol. 2019;: pubmed publisher
Zhang Z, He J, Zhao Y, Chen H, Tan N. Asiatic acid prevents renal fibrosis in UUO rats via promoting the production of 15d-PGJ2, an endogenous ligand of PPAR-γ. Acta Pharmacol Sin. 2019;: pubmed publisher
Zhu Y, Yu F, Tan Y, Hong Y, Meng T, Liu Y, et al. Reversing activity of cancer associated fibroblast for staged glycolipid micelles against internal breast tumor cells. Theranostics. 2019;9:6764-6779 pubmed publisher
Deng M, Cai X, Long L, Xie L, Ma H, Zhou Y, et al. CD36 promotes the epithelial-mesenchymal transition and metastasis in cervical cancer by interacting with TGF-β. J Transl Med. 2019;17:352 pubmed publisher
Wei Z, Zhao D, Zhang Y, Chen Y, Zhang S, Li Q, et al. Rosiglitazone ameliorates bile duct ligation-induced liver fibrosis by down-regulating NF-κB-TNF-α signaling pathway in a PPARγ-dependent manner. Biochem Biophys Res Commun. 2019;519:854-860 pubmed publisher
Zhang H, Yu J, Sun H, Zhao Y, Wang J, Zhang J, et al. Effects of ubiquitin-proteasome inhibitor on the expression levels of TNF-α and TGF-β1 in mice with viral myocarditis. Exp Ther Med. 2019;18:2799-2804 pubmed publisher
Zheng B, Fang Q, Wang X, Shi B, Zhao W, Chen C, et al. The effect of topical ramipril and losartan cream in inhibiting scar formation. Biomed Pharmacother. 2019;118:109394 pubmed publisher
Chen C, Li X, Wang L. Thymosinβ4 alleviates cholestatic liver fibrosis in mice through downregulating PDGF/PDGFR and TGFβ/Smad pathways. Dig Liver Dis. 2019;: pubmed publisher
Liu Y, Zhao J, Lü M, Wang H, Tang F. Retinoic acid attenuates cardiac injury induced by hyperglycemia in pre- and post-delivery mice. Can J Physiol Pharmacol. 2019;: pubmed publisher
Liu N, Feng J, Lu X, Yao Z, Liu Q, Lv Y, et al. Isorhamnetin Inhibits Liver Fibrosis by Reducing Autophagy and Inhibiting Extracellular Matrix Formation via the TGF-β1/Smad3 and TGF-β1/p38 MAPK Pathways. Mediators Inflamm. 2019;2019:6175091 pubmed publisher
Takahashi A, Tsujino T, Yamaguchi S, Isobe K, Watanabe T, Kitamura Y, et al. Distribution of platelets, transforming growth factor-β1, platelet-derived growth factor-BB, vascular endothelial growth factor and matrix metalloprotease-9 in advanced platelet-rich fibrin and concentrated growth factor matrices. J Investig Clin Dent. 2019;10:e12458 pubmed publisher
Liu Q, Borcherding N, Shao P, Cao H, Zhang W, Qi H. Identification of novel TGF-β regulated genes with pro-migratory roles. Biochim Biophys Acta Mol Basis Dis. 2019;1865:165537 pubmed publisher
Guo X, Zhu C, Liu X, Ge Y, Jiang X, Zhao W. Hyperoside protects against heart failure-induced liver fibrosis in rats. Acta Histochem. 2019;: pubmed publisher
Xue M, Li T, Wang Y, Chang Y, Cheng Y, Lu Y, et al. Empagliflozin prevents cardiomyopathy via sGC-cGMP-PKG pathway in type 2 diabetes mice. Clin Sci (Lond). 2019;133:1705-1720 pubmed publisher
Zhao Y, Zhu J, Shi B, Wang X, Lu Q, Li C, et al. The transcription factor LEF1 promotes tumorigenicity and activates the TGF-β signaling pathway in esophageal squamous cell carcinoma. J Exp Clin Cancer Res. 2019;38:304 pubmed publisher
Qin D, Zhang H, Zhang H, Sun T, Zhao H, Lee W. Anti-osteoporosis effects of osteoking via reducing reactive oxygen species. J Ethnopharmacol. 2019;244:112045 pubmed publisher
Wang Y, He G, Tang H, Shi Y, Kang X, Lyu J, et al. Aspirin inhibits inflammation and scar formation in the injury tendon healing through regulating JNK/STAT-3 signalling pathway. Cell Prolif. 2019;52:e12650 pubmed publisher
Zhao J, Li M, Wang Z, Chen J, Zhao J, Xu Y, et al. Role of PM2.5 in the development and progression of COPD and its mechanisms. Respir Res. 2019;20:120 pubmed publisher
Liang C, Xu J, Meng Q, Zhang B, Liu J, Hua J, et al. TGFB1-induced autophagy affects the pattern of pancreatic cancer progression in distinct ways depending on SMAD4 status. Autophagy. 2019;:1-15 pubmed publisher
Bu W, Wang Z, Meng L, Li X, Liu X, Chen Y, et al. Disulfiram inhibits epithelial-mesenchymal transition through TGFβ-ERK-Snail pathway independently of Smad4 to decrease oral squamous cell carcinoma metastasis. Cancer Manag Res. 2019;11:3887-3898 pubmed publisher
Chen W, Yan X, Xu A, Sun Y, Wang B, Huang T, et al. Dynamics of elastin in liver fibrosis: Accumulates late during progression and degrades slowly in regression. J Cell Physiol. 2019;: pubmed publisher
Evans R, Flores Borja F, Nassiri S, Miranda E, Lawler K, Grigoriadis A, et al. Integrin-Mediated Macrophage Adhesion Promotes Lymphovascular Dissemination in Breast Cancer. Cell Rep. 2019;27:1967-1978.e4 pubmed publisher
Xin X, Yao D, Zhang K, Han S, Liu D, Wang H, et al. Protective effects of Rosavin on bleomycin-induced pulmonary fibrosis via suppressing fibrotic and inflammatory signaling pathways in mice. Biomed Pharmacother. 2019;115:108870 pubmed publisher
Xue K, Zhang J, Li C, Li J, Wang C, Zhang Q, et al. The role and mechanism of transforming growth factor beta 3 in human myocardial infarction-induced myocardial fibrosis. J Cell Mol Med. 2019;23:4229-4243 pubmed publisher
Li X, Li C, Zhu G, Yuan W, Xiao Z. TGF-β1 Induces Epithelial-Mesenchymal Transition of Chronic Sinusitis with Nasal Polyps through MicroRNA-21. Int Arch Allergy Immunol. 2019;:1-17 pubmed publisher
He S, Chen D, Hu M, Zhang L, Liu C, Traini D, et al. Bronchial epithelial cell extracellular vesicles ameliorate epithelial-mesenchymal transition in COPD pathogenesis by alleviating M2 macrophage polarization. Nanomedicine. 2019;18:259-271 pubmed publisher
Li S, Song Y, Quach C, Guo H, Jang G, Maazi H, et al. Transcriptional regulation of autophagy-lysosomal function in BRAF-driven melanoma progression and chemoresistance. Nat Commun. 2019;10:1693 pubmed publisher
Yang L, Chen P, Luo M, Shi W, Hou D, Gao Y, et al. Inhibitory effects of total ginsenoside on bleomycin-induced pulmonary fibrosis in mice. Biomed Pharmacother. 2019;114:108851 pubmed publisher
Yu Z, Jv Y, Cai L, Tian X, Huo X, Wang C, et al. Gambogic acid attenuates liver fibrosis by inhibiting the PI3K/AKT and MAPK signaling pathways via inhibiting HSP90. Toxicol Appl Pharmacol. 2019;371:63-73 pubmed publisher
Hu B, Mao Z, Du Q, Jiang X, Wang Z, Xiao Z, et al. miR-93-5p targets Smad7 to regulate the transforming growth factor-β1/Smad3 pathway and mediate fibrosis in drug-resistant prolactinoma. Brain Res Bull. 2019;149:21-31 pubmed publisher
Diaz Delgado J, Groch K, Réssio R, Riskallah I, Sierra E, Sacchini S, et al. Comparative Immunopathology of Cetacean morbillivirus Infection in Free-Ranging Dolphins From Western Mediterranean, Northeast-Central, and Southwestern Atlantic. Front Immunol. 2019;10:485 pubmed publisher
Zhang L, Liu Y, Huang Z, Nan L, Wang F, Zhou S, et al. Toxicity Effects of Methylene Blue on Rat Intervertebral Disc Annulus Fibrosus Cells. Pain Physician. 2019;22:155-164 pubmed
Chen Y, Liu P, Sun P, Jiang J, Zhu Y, Dong T, et al. Oncogenic MSH6-CXCR4-TGFB1 Feedback Loop: A Novel Therapeutic Target of Photothermal Therapy in Glioblastoma Multiforme. Theranostics. 2019;9:1453-1473 pubmed publisher
Jin L, Qian Y, Zhou J, Dai L, Cao C, Zhu C, et al. Activated CRH receptors inhibit autophagy by repressing conversion of LC3BI to LC3BII. Cell Signal. 2019;58:119-130 pubmed publisher
Zhao J, Meng M, Zhang J, Li L, Zhu X, Zhang L, et al. Astaxanthin ameliorates renal interstitial fibrosis and peritubular capillary rarefaction in unilateral ureteral obstruction. Mol Med Rep. 2019;19:3168-3178 pubmed publisher
Han W, Wang C, Yang Z, Mu L, Wu M, Chen N, et al. SRT1720 retards renal fibrosis via inhibition of HIF1α /GLUT1 in diabetic nephropathy. J Endocrinol. 2019;: pubmed publisher
Zhang H, You L, Zhao M. Rosiglitazone attenuates paraquat-induced lung fibrosis in rats in a PPAR gamma-dependent manner. Eur J Pharmacol. 2019;851:133-143 pubmed publisher
Naciri I, Laisné M, Ferry L, Bourmaud M, Gupta N, Di Carlo S, et al. Genetic screens reveal mechanisms for the transcriptional regulation of tissue-specific genes in normal cells and tumors. Nucleic Acids Res. 2019;47:3407-3421 pubmed publisher
Ruiz M, Maumus M, Fonteneau G, Pers Y, Ferreira R, Dagneaux L, et al. TGFβi is involved in the chondrogenic differentiation of mesenchymal stem cells and is dysregulated in osteoarthritis. Osteoarthritis Cartilage. 2019;27:493-503 pubmed publisher
Rusmini P, Cortese K, Crippa V, Cristofani R, Cicardi M, Ferrari V, et al. Trehalose induces autophagy via lysosomal-mediated TFEB activation in models of motoneuron degeneration. Autophagy. 2019;15:631-651 pubmed publisher
Liang J, Chen C, Liu H, Liu X, Li Z, Hu J, et al. Gossypol Promotes Bone Formation in Ovariectomy-Induced Osteoporosis through Regulating Cell Apoptosis. Biomed Res Int. 2018;2018:3635485 pubmed publisher
Huang G, Yang L, Zhou W, Tang X, Wang Y, Ma Z, et al. Study on Cardiotoxicity and Mechanism of "Fuzi" Extracts Based on Metabonomics. Int J Mol Sci. 2018;19: pubmed publisher
Song S, Qiu D, Luo F, Wei J, Wu M, Wu H, et al. Knockdown of NLRP3 alleviates high glucose or TGFB1-induced EMT in human renal tubular cells. J Mol Endocrinol. 2018;61:101-113 pubmed publisher
Zhao Z, Shen W, Zhu H, Lin L, Jiang G, Zhu Y, et al. Zoledronate inhibits fibroblasts' proliferation and activation via targeting TGF-β signaling pathway. Drug Des Devel Ther. 2018;12:3021-3031 pubmed publisher
Song Y, Tang C, Yin C. Combination antitumor immunotherapy with VEGF and PIGF siRNA via systemic delivery of multi-functionalized nanoparticles to tumor-associated macrophages and breast cancer cells. Biomaterials. 2018;185:117-132 pubmed publisher
Ju Q, Li M, Chen G, Wang H, Shi Q, Ge X, et al. Overexpression of YOD1 Promotes the Migration of Human Oral Keratinocytes by Enhancing TGF-β3 Signaling. Biomed Environ Sci. 2018;31:499-506 pubmed publisher
Ye X, He L, Ma J, Li Y, Zhang M, Yang J, et al. Downregulation of Glt25d1 aggravates carbon tetrachloride‑induced acute hepatic injury through activation of the TGF‑β1/Smad2 signaling pathway. Mol Med Rep. 2018;18:3611-3618 pubmed publisher
Wu M, Han W, Song S, Du Y, Liu C, Chen N, et al. NLRP3 deficiency ameliorates renal inflammation and fibrosis in diabetic mice. Mol Cell Endocrinol. 2018;478:115-125 pubmed publisher
Cao L, Chen Y, Lu L, Liu Y, Wang Y, Fan J, et al. Angiotensin II upregulates fibroblast-myofibroblast transition through Cx43-dependent CaMKII and TGF-β1 signaling in neonatal rat cardiac fibroblasts. Acta Biochim Biophys Sin (Shanghai). 2018;50:843-852 pubmed publisher
Hu B, Mao Z, Jiang X, He D, Wang Z, Wang X, et al. Role of TGF-β1/Smad3-mediated fibrosis in drug resistance mechanism of prolactinoma. Brain Res. 2018;1698:204-212 pubmed publisher
Qin W, Liu B, Yi M, Li L, Tang Y, Wu B, et al. Antifibrotic Agent Pirfenidone Protects against Development of Radiation-Induced Pulmonary Fibrosis in a Murine Model. Radiat Res. 2018;190:396-403 pubmed publisher
Wang Q, Lv C, Sun Y, Han X, Wang S, Mao Z, et al. The Role of Alpha-Lipoic Acid in the Pathomechanism of Acute Ischemic Stroke. Cell Physiol Biochem. 2018;48:42-53 pubmed publisher
Wang Y, Guan M, Zhao X, Li X. Effects of garlic polysaccharide on alcoholic liver fibrosis and intestinal microflora in mice. Pharm Biol. 2018;56:325-332 pubmed publisher
Qin G, Xia J, Zhang Y, Guo L, Chen R, Sang N. Ambient fine particulate matter exposure induces reversible cardiac dysfunction and fibrosis in juvenile and older female mice. Part Fibre Toxicol. 2018;15:27 pubmed publisher
Liu R, Wang W, Wang S, Xie W, Li H, Ning B. microRNA-21 regulates astrocytic reaction post-acute phase of spinal cord injury through modulating TGF-β signaling. Aging (Albany NY). 2018;10:1474-1488 pubmed publisher
Zhao Z, Han Y, Zhang Z, Li W, Ji X, Liu X, et al. Total glucosides of paeony improves the immunomodulatory capacity of MSCs partially via the miR-124/STAT3 pathway in oral lichen planus. Biomed Pharmacother. 2018;105:151-158 pubmed publisher
Liu F, Wen Y, Kang J, Wei C, Wang M, Zheng Z, et al. Regulation of TLR4 expression mediates the attenuating effect of erythropoietin on inflammation and myocardial fibrosis in rat heart. Int J Mol Med. 2018;42:1436-1444 pubmed publisher
Gu C, Wang X, Long T, Wang X, Zhong Y, Ma Y, et al. FSTL1 interacts with VIM and promotes colorectal cancer metastasis via activating the focal adhesion signalling pathway. Cell Death Dis. 2018;9:654 pubmed publisher
Lu H, Wu L, Liu L, Ruan Q, Zhang X, Hong W, et al. Quercetin ameliorates kidney injury and fibrosis by modulating M1/M2 macrophage polarization. Biochem Pharmacol. 2018;154:203-212 pubmed publisher
Zhang B, Li X, Chen C, Jiang W, Lu D, Liu Q, et al. Renal Denervation Effects on Myocardial Fibrosis and Ventricular Arrhythmias in Rats with Ischemic Cardiomyopathy. Cell Physiol Biochem. 2018;46:2471-2479 pubmed publisher
Gao X, Wang C, Ning C, Liu K, Wang X, Liu Z, et al. Hepatoprotection of auraptene from peels of citrus fruits against thioacetamide-induced hepatic fibrosis in mice by activating farnesoid X receptor. Food Funct. 2018;9:2684-2694 pubmed publisher
Gan L, Li X, Zhu M, Chen C, Luo H, Zhou Q. Acteoside relieves mesangial cell injury by regulating Th22 cell chemotaxis and proliferation in IgA nephropathy. Ren Fail. 2018;40:364-370 pubmed publisher
Li A, Peng R, Sun Y, Liu H, Peng H, Zhang Z. LincRNA 1700020I14Rik alleviates cell proliferation and fibrosis in diabetic nephropathy via miR-34a-5p/Sirt1/HIF-1? signaling. Cell Death Dis. 2018;9:461 pubmed publisher
Xu J, Wang J, Cheng Y, Li X, He M, Zhu J, et al. Glucagon-Like Peptide-1 Mediates the Protective Effect of the Dipeptidyl Peptidase IV Inhibitor on Renal Fibrosis via Reducing the Phenotypic Conversion of Renal Microvascular Cells in Monocrotaline-Treated Rats. Biomed Res Int. 2018;2018:1864107 pubmed publisher
Liu Y, Wang T, Liu X, Wen Y, Xu T, Yu X, et al. Overexpression of zinc-α2-glycoprotein suppressed seizures and seizure-related neuroflammation in pentylenetetrazol-kindled rats. J Neuroinflammation. 2018;15:92 pubmed publisher
Wang E, Fan Q, Yue Y, Xu L. Ursolic Acid Attenuates High Glucose-Mediated Mesangial Cell Injury by Inhibiting the Phosphatidylinositol 3-Kinase/Akt/Mammalian Target of Rapamycin (PI3K/Akt/mTOR) Signaling Pathway. Med Sci Monit. 2018;24:846-854 pubmed
Zhu Y, Wen L, Shao S, Tan Y, Meng T, Yang X, et al. Inhibition of tumor-promoting stroma to enforce subsequently targeting AT1R on tumor cells by pathological inspired micelles. Biomaterials. 2018;161:33-46 pubmed publisher
Zhang R, Wei Y, Zhao C, Song H, Shen N, Cui X, et al. EDIL3 depletion suppress epithelial-mesenchymal transition of lens epithelial cells via transforming growth factor ? pathway. Int J Ophthalmol. 2018;11:18-24 pubmed publisher
Liu H, Zhang M, Xu S, Zhang J, Zou J, Yang C, et al. HOXC8 promotes proliferation and migration through transcriptional up-regulation of TGFβ1 in non-small cell lung cancer. Oncogenesis. 2018;7:1 pubmed publisher
Peng X, Dai C, Liu Q, Li J, Qiu J. Curcumin Attenuates on Carbon Tetrachloride-Induced Acute Liver Injury in Mice via Modulation of the Nrf2/HO-1 and TGF-β1/Smad3 Pathway. Molecules. 2018;23: pubmed publisher
Xiao Y, Ye J, Zhou Y, Huang J, Liu X, Huang B, et al. Baicalin inhibits pressure overload-induced cardiac fibrosis through regulating AMPK/TGF-?/Smads signaling pathway. Arch Biochem Biophys. 2018;640:37-46 pubmed publisher
Li D, Wang X, Huang Q, Li S, Zhou Y, Li Z. Cardioprotection of CAPE-oNO2 against myocardial ischemia/reperfusion induced ROS generation via regulating the SIRT1/eNOS/NF-?B pathway in vivo and in vitro. Redox Biol. 2018;15:62-73 pubmed publisher
Qiao Y, Xu L, Tao X, Yin L, Qi Y, Xu Y, et al. Protective effects of dioscin against fructose-induced renal damage via adjusting Sirt3-mediated oxidative stress, fibrosis, lipid metabolism and inflammation. Toxicol Lett. 2018;284:37-45 pubmed publisher
Yang L, Tucker D, Dong Y, Wu C, Lu Y, Li Y, et al. Photobiomodulation therapy promotes neurogenesis by improving post-stroke local microenvironment and stimulating neuroprogenitor cells. Exp Neurol. 2018;299:86-96 pubmed publisher
Gan L, Zhou Q, Li X, Chen C, Meng T, Pu J, et al. Intrinsic renal cells induce lymphocytosis of Th22 cells from IgA nephropathy patients through B7-CTLA-4 and CCL-CCR pathways. Mol Cell Biochem. 2018;441:191-199 pubmed publisher
Wang X, Li D, Fan L, Xiao Q, Zuo H, Li Z. CAPE-pNO2 ameliorated diabetic nephropathy through regulating the Akt/NF-?B/ iNOS pathway in STZ-induced diabetic mice. Oncotarget. 2017;8:114506-114525 pubmed publisher
Xiang H, Tao X, Xia S, Qu J, Song H, Liu J, et al. Emodin Alleviates Sodium Taurocholate-Induced Pancreatic Acinar Cell Injury via MicroRNA-30a-5p-Mediated Inhibition of High-Temperature Requirement A/Transforming Growth Factor Beta 1 Inflammatory Signaling. Front Immunol. 2017;8:1488 pubmed publisher
Li Y, Zou N, Wang J, Wang K, Li F, Chen F, et al. TGF-?1/Smad3 Signaling Pathway Mediates T-2 Toxin-Induced Decrease of Type II Collagen in Cultured Rat Chondrocytes. Toxins (Basel). 2017;9: pubmed publisher
Wei J, Zhang G, Zhang X, Xu D, Gao J, Fan J. Anthocyanins Delay Ageing-Related Degenerative Changes in the Liver. Plant Foods Hum Nutr. 2017;72:425-431 pubmed publisher
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product information
CatalogNo :
21898-1-AP
AntigenName :
TGF-beta 1
Package :
150UL
Price :
299 USD
Exsists20ul :
20ul trial size available
FullName :
transforming growth factor, beta 1
Immunogen :
Fusion Protein
Species :
dog, human, mouse, rat, zebrafish
Host :
Rabbit
IsConjugated :
Unconjugated
AntigenSpecies :
human
Application :
WB, IHC, IF, ELISA
Clonlity :
Polyclonal
IsoType :
IgG
Synonyms :
CED, DPD1, LAP, TGF beta 1, tgf beta1, TGFB, TGFB1, TGFbeta, tgfbeta1, tgf-beta1, TGFβ, TGF-β, TGFβ1, TGF-β1
PrimaryOrSecondary :
Primary
AntibodyBuffer :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
GenBankNo :
BC000125
Category :
Binding Proteins;Cell Cycle;Cytoskeleton/Scaffold Proteins;Development;Growth Factor/Cytokine/Hormone;Membrane Proteins;Neurology;Signal transduction;
PurifyMethod :
Antigen affinity purification
NewAb :
False
IsSellable :
True
Feature :
siRNA
AppTiter :
IF 1:50 ; IHC 1:200 ; WB 1:2500 ;
company information
Proteintech Group
2201 W. Campbell Park Dr. STE12
Chicago, IL 60612
Proteintech@ptglab.com
https://www.ptglab.com
1-312-455-8498
headquarters: USA
At Proteintech, we produce every single antibody we sell; we do not rely on or supply to any other antibody providers: our products are unique and we are 100% accountable for each one. We realize this accountability by validating in-house, providing extensive technical support and guaranteeing your success: in addition to helping you troubleshoot your experiment, we will offer you a full cash refund if you are in any way dissatisfied. We can guarantee satisfaction because we have confidence in our products, confidence cultivated by the science behind our antibodies: we make them using as much of the native protein as possible, and purifying them using affinity purification with the original antigen. We carry out antibody production over a 102-day period, which allows for better antigen fitting to MHC molecules and affinity maturation in the host. This approach results in higher affinity antibodies with greater sensitivity, which you can use in any application and in multiple species.
You can only buy Proteintech antibodies directly from Proteintech or via one of its approved distributors — when you receive your antibody and see the Proteintech logo on the vial, know that you hold something that is truly unique.