This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Proteintech Group
product type :
antibody
product name :
IL-6
catalog :
21865-1-AP
quantity :
150UL
price :
299 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry
citations: 165
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; 1:3000; loading ...; fig 8b, 13a
Xu B, Lang L, Li S, Guo J, Wang J, Yang H, et al. Microglia Activated by Excess Cortisol Induce HMGB1 Acetylation and Neuroinflammation in the Hippocampal DG Region of Mice Following Cold Exposure. Biomolecules. 2019;9: pubmed publisher
  • western blot; human; loading ...; fig 6e
Xie C, Zhu J, Jiang Y, Chen J, Wang X, Geng S, et al. Sulforaphane Inhibits the Acquisition of Tobacco Smoke-Induced Lung Cancer Stem Cell-Like Properties via the IL-6/ΔNp63α/Notch Axis. Theranostics. 2019;9:4827-4840 pubmed publisher
  • western blot; rat; 1:500; fig 1e
Wu J, Hu G, Lu Y, Zheng J, Chen J, Wang X, et al. Palmitic acid aggravates inflammation of pancreatic acinar cells by enhancing unfolded protein response induced CCAAT-enhancer-binding protein ?-CCAAT-enhancer-binding protein ? activation. Int J Biochem Cell Biol. 2016;79:181-193 pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 4a
Wang L, Zhao R, Liu C, Liu M, Li S, Li J, et al. A fundamental study on the dynamics of multiple biomarkers in mouse excisional wounds for wound age estimation. J Forensic Leg Med. 2016;39:138-46 pubmed publisher
Yi P, Xu X, Qiu B, Li H. Impact of chitosan membrane culture on the expression of pro- and anti-inflammatory cytokines in mesenchymal stem cells. Exp Ther Med. 2020;20:3695-3702 pubmed publisher
Li J, Guo Y, Chen Y, Liu Q, Chen Y, Tan L, et al. miR-124-3p increases in high glucose induced osteocyte-derived exosomes and regulates galectin-3 expression: A possible mechanism in bone remodeling alteration in diabetic periodontitis. FASEB J. 2020;: pubmed publisher
Yan C, Zhang L, Yang L, Zhang Q, Wang X. C/EBPγ is a critical negative regulator of LPS-/IgG immune complex-induced acute lung injury through the downregulation of C/EBPβ-/C/EBPδ-dependent C/EBP transcription activation. FASEB J. 2020;: pubmed publisher
Fu X, Xu L, Fu B, Wei K, Liu Y, Liao B, et al. Pachymic acid protects oocyte by improving the ovarian microenvironment in PCOS mice. Biol Reprod. 2020;: pubmed publisher
Wang Y, Zhu Y, Niu J, Deng Q, Guo S, Jiang H, et al. A novel bile acid analog, A17, ameliorated non-alcoholic steatohepatitis in high-fat diet-fed hamsters. Toxicol Appl Pharmacol. 2020;404:115169 pubmed publisher
Ding J, Yang C, Cheng Y, Wang J, Zhang S, Yan S, et al. Trophoblast-derived IL-6 serves as an important factor for normal pregnancy by activating Stat3-mediated M2 macrophages polarization. Int Immunopharmacol. 2020;:106788 pubmed publisher
Yang K, Fan B, Zhao Q, Ji Y, Liu P, Gao S, et al. Hirudin Ameliorates Renal Interstitial Fibrosis via Regulating TGF-β1/Smad and NF-κB Signaling in UUO Rat Model. Evid Based Complement Alternat Med. 2020;2020:7291075 pubmed publisher
Liu Z, Ye S, Zhong X, Wang W, Lai C, Yang W, et al. Pretreatment with the ALDH2 activator Alda‑1 protects rat livers from ischemia/reperfusion injury by inducing autophagy. Mol Med Rep. 2020;22:2373-2385 pubmed publisher
Zajaczkowska R, Kwiatkowski K, Pawlik K, Piotrowska A, Rojewska E, Makuch W, et al. Metamizole relieves pain by influencing cytokine levels in dorsal root ganglia in a rat model of neuropathic pain. Pharmacol Rep. 2020;: pubmed publisher
Man S, Yao J, Lv P, Liu Y, Yang L, Ma L. Curcumin-enhanced antitumor effects of sorafenib via regulating the metabolism and tumor microenvironment. Food Funct. 2020;11:6422-6432 pubmed publisher
Yan C, Ma Z, Ma H, Li Q, Zhai Q, Jiang T, et al. Mitochondrial Transplantation Attenuates Brain Dysfunction in Sepsis by Driving Microglial M2 Polarization. Mol Neurobiol. 2020;57:3875-3890 pubmed publisher
Zhou X, Liu Z, Ying K, Wang H, Liu P, Ji X, et al. WJ-39, an Aldose Reductase Inhibitor, Ameliorates Renal Lesions in Diabetic Nephropathy by Activating Nrf2 Signaling. Oxid Med Cell Longev. 2020;2020:7950457 pubmed publisher
Sun H, Ding J, Zheng H, Lv K, Hu Y, Luo Y, et al. The Effects of Sidt2 on the Inflammatory Pathway in Mouse Mesangial Cells. Mediators Inflamm. 2020;2020:3560793 pubmed publisher
Yadav V, Huang Y, George T, Wei P, Sumitra M, Ho C, et al. Preclinical Evaluation of the Novel Small-Molecule MSI-N1014 for Treating Drug-Resistant Colon Cancer via the LGR5/β-catenin/miR-142-3p Network and Reducing Cancer-Associated Fibroblast Transformation. Cancers (Basel). 2020;12: pubmed publisher
Zhang Y, Sun H, Wang T, Liu X, Liu C, Shen F, et al. Pterostilbene Ameliorates Glycemic Control, Dyslipidemia and Liver Injury in Type 2 Diabetes Rats. Biomed Environ Sci. 2020;33:365-368 pubmed publisher
Ho C, Lin Y, Chen H, Ho W, Sun G, Hsiao M, et al. CX3CR1-microglia mediates neuroinflammation and blood pressure regulation in the nucleus tractus solitarii of fructose-induced hypertensive rats. J Neuroinflammation. 2020;17:185 pubmed publisher
Dong X, Kong F, Liu C, Dai S, Zhang Y, Xiao F, et al. Pulp stem cells with hepatocyte growth factor overexpression exhibit dual effects in rheumatoid arthritis. Stem Cell Res Ther. 2020;11:229 pubmed publisher
Hu W, Wu X, Yu D, Zhao L, Zhu X, Li X, et al. Regulation of JNK signaling pathway and RIPK3/AIF in necroptosis-mediated global cerebral ischemia/reperfusion injury in rats. Exp Neurol. 2020;331:113374 pubmed publisher
Chang Z, Wang J, Jing Z, Ma P, Xu Q, Na J, et al. Protective effects of isorhamnetin on pulmonary arterial hypertension: in vivo and in vitro studies. Phytother Res. 2020;: pubmed publisher
Zhang C, Jia Y, Liu B, Wang G, Zhang Y. TLR4 knockout upregulates the expression of Mfn2 and PGC-1α in a high-fat diet and ischemia-reperfusion mice model of liver injury. Life Sci. 2020;254:117762 pubmed publisher
Yang X, Yang R, Chen M, Zhou Q, Zheng Y, Lu C, et al. KGF-2 and FGF-21 poloxamer 407 hydrogel coordinates inflammation and proliferation homeostasis to enhance wound repair of scalded skin in diabetic rats. BMJ Open Diabetes Res Care. 2020;8: pubmed publisher
Zhang Z, Sun C, Li C, Jiao X, Griffin B, Dongol S, et al. Upregulated MELK Leads to Doxorubicin Chemoresistance and M2 Macrophage Polarization via the miR-34a/JAK2/STAT3 Pathway in Uterine Leiomyosarcoma. Front Oncol. 2020;10:453 pubmed publisher
Chu X, Zhang Y, Xue Y, Li Z, Shi J, Wang H, et al. Crocin protects against cardiotoxicity induced by doxorubicin through TLR-2/NF-κB signal pathway in vivo and vitro. Int Immunopharmacol. 2020;84:106548 pubmed publisher
Qiu J, Peng P, Xin M, Wen Z, Chen Z, Lin S, et al. ZBTB20-mediated titanium particle-induced peri-implant osteolysis by promoting macrophage inflammatory responses. Biomater Sci. 2020;8:3147-3163 pubmed publisher
Shen X, Cheng Y, Dong Q, Zheng M. MicroRNA-675-3p regulates IL-1β-stimulated human chondrocyte apoptosis and cartilage degradation by targeting GNG5. Biochem Biophys Res Commun. 2020;527:458-465 pubmed publisher
Xu S, Mao Y, Wu J, Feng J, Li J, Wu L, et al. TGF-β/Smad and JAK/STAT pathways are involved in the anti-fibrotic effects of propylene glycol alginate sodium sulphate on hepatic fibrosis. J Cell Mol Med. 2020;24:5224-5237 pubmed publisher
Xu S, Jiang C, Liu H, Zhang H, Liao H, Wang X, et al. Integrin-α9 and Its Corresponding Ligands Play Regulatory Roles in Chronic Periodontitis. Inflammation. 2020;43:1488-1497 pubmed publisher
Wang H, Ding Y, Zhang W, Wei K, Pei Y, Zou C, et al. Oxymatrine Liposomes for Intervertebral Disc Treatment: Formulation, in vitro and vivo Assessments. Drug Des Devel Ther. 2020;14:921-931 pubmed publisher
Ma X, Zhou Y, Qiao B, Jiang S, Shen Q, Han Y, et al. Androgen aggravates liver fibrosis by activation of NLRP3 inflammasome in CCl4-induced liver injury mouse model. Am J Physiol Endocrinol Metab. 2020;318:E817-E829 pubmed publisher
Liu Y, Zhang X, Yan D, Wang Y, Wang N, Liu Y, et al. Chronic acrylamide exposure induced glia cell activation, NLRP3 infl-ammasome upregulation and cognitive impairment. Toxicol Appl Pharmacol. 2020;393:114949 pubmed publisher
Gao L, Qian B, Chen H, Wang A, Li Q, Li J, et al. Hic-5 deficiency attenuates hepatic ischemia reperfusion injury through TLR4/NF-κB signaling pathways. Life Sci. 2020;249:117517 pubmed publisher
Jin W, Xue Y, Xue Y, Han X, Song Q, Zhang J, et al. Tannic acid ameliorates arsenic trioxide-induced nephrotoxicity, contribution of NF-κB and Nrf2 pathways. Biomed Pharmacother. 2020;126:110047 pubmed publisher
Wan Y, Wu H, Li Y, Xu Z, Yang J, Liu C, et al. TSG-6 Inhibits Oxidative Stress and Induces M2 Polarization of Hepatic Macrophages in Mice With Alcoholic Hepatitis via Suppression of STAT3 Activation. Front Pharmacol. 2020;11:10 pubmed publisher
Yu Q, Wang D, Wen X, Tang X, Qi D, He J, et al. Adipose-derived exosomes protect the pulmonary endothelial barrier in ventilator-induced lung injury by inhibiting the TRPV4/Ca2+ signaling pathway. Am J Physiol Lung Cell Mol Physiol. 2020;318:L723-L741 pubmed publisher
Liu S, Yang Y, Gao H, Zhou N, Wang P, Zhang Y, et al. Trehalose attenuates renal ischemia-reperfusion injury by enhancing autophagy and inhibiting oxidative stress and inflammation. Am J Physiol Renal Physiol. 2020;318:F994-F1005 pubmed publisher
Zhou L, Yao M, Tian Z, Song Y, Sun Y, Ye J, et al. Echinacoside attenuates inflammatory response in a rat model of cervical spondylotic myelopathy via inhibition of excessive mitochondrial fission. Free Radic Biol Med. 2020;152:697-714 pubmed publisher
Zhou S, Chen S, Xie W, Guo X, Zhao J. Microglia polarization of hippocampus is involved in the mechanism of Apelin-13 ameliorating chronic water immersion restraint stress-induced depression-like behavior in rats. Neuropeptides. 2020;81:102006 pubmed publisher
Zhang M, Fan H, Tan S, Tang Q, Liu X, Zuo D, et al. The Chinese medicinal herb decoction QRZSLXF enhances anti-inflammatory effect in TNBS-induced colitis via balancing Th17/Tregs differentiation. J Ethnopharmacol. 2020;251:112549 pubmed publisher
Du H, Zhao A, Wang Q, Yang X, Ren D. Supplementation of Inulin with Various Degree of Polymerization Ameliorates Liver Injury and Gut Microbiota Dysbiosis in High Fat-Fed Obese Mice. J Agric Food Chem. 2020;68:779-787 pubmed publisher
Liu D, Dong Z, Xiang F, Liu H, Wang Y, Wang Q, et al. Dendrobium Alkaloids Promote Neural Function After Cerebral Ischemia-Reperfusion Injury Through Inhibiting Pyroptosis Induced Neuronal Death in both In Vivo and In Vitro Models. Neurochem Res. 2020;45:437-454 pubmed publisher
Zhang Y, Zhang Z, Wei R, Miao X, Sun S, Liang G, et al. IL (Interleukin)-6 Contributes to Deep Vein Thrombosis and Is Negatively Regulated by miR-338-5p. Arterioscler Thromb Vasc Biol. 2020;40:323-334 pubmed publisher
Rajendran S, Anquetil F, Quesada Masachs E, Graef M, Gonzalez N, McArdle S, et al. IL-6 is present in beta and alpha cells in human pancreatic islets: Expression is reduced in subjects with type 1 diabetes. Clin Immunol. 2020;211:108320 pubmed publisher
Zhang P, Yin Y, Wang T, Li W, Li C, Zeng X, et al. Maresin 1 mitigates concanavalin A-induced acute liver injury in mice by inhibiting ROS-mediated activation of NF-κB signaling. Free Radic Biol Med. 2020;147:23-36 pubmed publisher
Jin W, Zhang Y, Xue Y, Han X, Zhang X, Ma Z, et al. Crocin attenuates isoprenaline-induced myocardial fibrosis by targeting TLR4/NF-κB signaling: connecting oxidative stress, inflammation, and apoptosis. Naunyn Schmiedebergs Arch Pharmacol. 2020;393:13-23 pubmed publisher
Sun B, Luo X, Yang C, Liu P, Yang Y, Dong X, et al. Therapeutic Effects of Human Urine-Derived Stem Cells in a Rat Model of Cisplatin-Induced Acute Kidney Injury In Vivo and In Vitro. Stem Cells Int. 2019;2019:8035076 pubmed publisher
Zhao W, Fang Q, Wang X, Wang X, Zhang T, Shi B, et al. Chitosan-calcium alginate dressing promotes wound healing: A preliminary study. Wound Repair Regen. 2019;: pubmed publisher
Huang M, Guo M, Wang K, Wu K, Li Y, Tian T, et al. HMGB1 Mediates Paraquat-Induced Neuroinflammatory Responses via Activating RAGE Signaling Pathway. Neurotox Res. 2019;: pubmed publisher
Wang Z, Liang M, Li H, Cai L, Yang L. Rice Protein Exerts Anti-Inflammatory Effect in Growing and Adult Rats via Suppressing NF-κB Pathway. Int J Mol Sci. 2019;20: pubmed publisher
Uyama N, Tsutsui H, Wu S, Yasuda K, Hatano E, Qin X, et al. Anti-interleukin-6 receptor antibody treatment ameliorates postoperative adhesion formation. Sci Rep. 2019;9:17558 pubmed publisher
Narimiya T, Kanzaki H, Yamaguchi Y, Wada S, Katsumata Y, Tanaka K, et al. Nrf2 activation in osteoblasts suppresses osteoclastogenesis via inhibiting IL-6 expression. Bone Rep. 2019;11:100228 pubmed publisher
Yang L, Sun Y, Liu Y, Yin N, Bu F, Yu H, et al. PTP1B promotes macrophage activation by regulating the NF-κB pathway in alcoholic liver injury. Toxicol Lett. 2019;319:11-21 pubmed publisher
Dai X, Zhang S, Cheng H, Cai D, Chen X, Huang Z. FA2H Exhibits Tumor Suppressive Roles on Breast Cancers via Cancer Stemness Control. Front Oncol. 2019;9:1089 pubmed publisher
Grevenstein D, Heilig J, Dargel J, Oppermann J, Eysel P, Brochhausen C, et al. COMP in the Infrapatellar Fat Pad-Results of a Prospective Histological, Immunohistological, and Biochemical Case-Control Study. J Orthop Res. 2019;: pubmed publisher
Luo Y, Pang X, Ansari A, Wu X, Li H, Zhang Z, et al. Visfatin Exerts Immunotherapeutic Effects in Lipopolysaccharide-Induced Acute Lung Injury in Murine Model. Inflammation. 2019;: pubmed publisher
Rao S, Li Q, Wu H, Zhao M, Wang A, Zhang G, et al. Juxtaposition of IL-1β and IFN-γ expression and apoptosis of keratinocytes in adult-onset Still's disease. Expert Rev Clin Immunol. 2019;15:1341-1350 pubmed publisher
Liu C, Ding R, Huang W, Miao L, Li J, Li Y. Sevoflurane Protects against Intestinal Ischemia-Reperfusion Injury by Activating Peroxisome Proliferator-Activated Receptor Gamma/Nuclear Factor-κB Pathway in Rats. Pharmacology. 2019;:1-12 pubmed publisher
Chen W, Fan H, Liang R, Zhang R, Zhang J, Zhu J. Taraxacum officinale extract ameliorates dextran sodium sulphate-induced colitis by regulating fatty acid degradation and microbial dysbiosis. J Cell Mol Med. 2019;23:8161-8172 pubmed publisher
Geng Z, Li Y, Cui Q, Du R, Tian J. Exploration of the mechanisms of Ge Gen Decoction against influenza A virus infection. Chin J Nat Med. 2019;17:650-662 pubmed publisher
Ruan J, Li Z, Zhang Y, Chen Y, Liu M, Han L, et al. Bioactive Constituents from the Roots of Eurycoma longifolia. Molecules. 2019;24: pubmed publisher
Yu J, Ming H, Li H, Yu B, Chu M, Zhu H, et al. IMM-H007, a novel small molecule inhibitor for atherosclerosis, represses endothelium inflammation by regulating the activity of NF-κB and JNK/AP1 signaling. Toxicol Appl Pharmacol. 2019;381:114732 pubmed publisher
Qi W, Yang X, Ye N, Li S, Han Q, Huang J, et al. TLR4 gene in the regulation of periodontitis and its molecular mechanism. Exp Ther Med. 2019;18:1961-1966 pubmed publisher
Yokomizo R, Yanaihara N, Yamaguchi N, Saito M, Kawabata A, Takahashi K, et al. MicroRNA-34a/IL-6R pathway as a potential therapeutic target for ovarian high-grade serous carcinoma. Oncotarget. 2019;10:4880-4893 pubmed publisher
Trautz F, Franke H, Bohnert S, Hammer N, Müller W, Stassart R, et al. Survival-time dependent increase in neuronal IL-6 and astroglial GFAP expression in fatally injured human brain tissue. Sci Rep. 2019;9:11771 pubmed publisher
Zhu L, Li L, Wang X, Pan L, Mei Y, Fu Y, et al. M1 macrophages regulate TLR4/AP1 via paracrine to promote alveolar bone destruction in periodontitis. Oral Dis. 2019;: pubmed publisher
Xue X, Luo L. LncRNA HIF1A-AS1 contributes to ventricular remodeling after myocardial ischemia/reperfusion injury by adsorption of microRNA-204 to regulating SOCS2 expression. Cell Cycle. 2019;18:2465-2480 pubmed publisher
Huang Y, Wang F, Li H, Xu S, Xu W, Pan X, et al. Inhibition of Fibroblast Growth Factor Receptor by AZD4547 Protects Against Inflammation in Septic Mice. Inflammation. 2019;: pubmed publisher
Wu Y, Lin Z, Yan Z, Wang Z, Fu X, Yu K. Sinomenine contributes to the inhibition of the inflammatory response and the improvement of osteoarthritis in mouse-cartilage cells by acting on the Nrf2/HO-1 and NF-κB signaling pathways. Int Immunopharmacol. 2019;75:105715 pubmed publisher
Zhong X, Xiao Q, Liu Z, Wang W, Lai C, Yang W, et al. TAK242 suppresses the TLR4 signaling pathway and ameliorates DCD liver IRI in rats. Mol Med Rep. 2019;20:2101-2110 pubmed publisher
Xu Z, Li L, Qian Y, Song Y, Qin L, Duan Y, et al. Upregulation of IL-6 in CUL4B-deficient myeloid-derived suppressive cells increases the aggressiveness of cancer cells. Oncogene. 2019;: pubmed publisher
Wang Y, He G, Tang H, Shi Y, Kang X, Lyu J, et al. Aspirin inhibits inflammation and scar formation in the injury tendon healing through regulating JNK/STAT-3 signalling pathway. Cell Prolif. 2019;52:e12650 pubmed publisher
Dai X, Cheng H, Chen X, Li T, Zhang J, Jin G, et al. FOXA1 is Prognostic of Triple Negative Breast Cancers by Transcriptionally Suppressing SOD2 and IL6. Int J Biol Sci. 2019;15:1030-1041 pubmed publisher
Deng J, Xu T, Yang J, Zhang K, Li Q, Yu X, et al. Sema7A, a brain immune regulator, regulates seizure activity in PTZ-kindled epileptic rats. CNS Neurosci Ther. 2019;: pubmed publisher
Luo W, Shen Z, Deng M, Li X, Tan B, Xiao M, et al. Roseburia intestinalis supernatant ameliorates colitis induced in mice by regulating the immune response. Mol Med Rep. 2019;20:1007-1016 pubmed publisher
Wang L, Qiu J, He J, Liu W, Ge X, Zhou F, et al. Suppression of miR-143 contributes to overexpression of IL-6, HIF-1α and NF-κB p65 in Cr(VI)-induced human exposure and tumor growth. Toxicol Appl Pharmacol. 2019;:114603 pubmed publisher
Periasamy S, Wu W, Chien S, Liu C, Liu M. Dietary Ziziphus jujuba Fruit Attenuates Colitis-Associated Tumorigenesis: A Pivotal Role of the NF-κB/IL-6/JAK1/STAT3 Pathway. Nutr Cancer. 2019;:1-13 pubmed publisher
Bian X, Bai Y, Su X, Zhao G, Sun G, Li D. Knockdown of periostin attenuates 5/6 nephrectomy-induced intrarenal renin-angiotensin system activation, fibrosis, and inflammation in rats. J Cell Physiol. 2019;234:22857-22873 pubmed publisher
Yu H, Sun L, Cui J, Li Y, Yan Y, Wei X, et al. Three kinds of corneal host cells contribute differently to corneal neovascularization. EBioMedicine. 2019;: pubmed publisher
Chen C, Lee T, Leu Y, Wang S. Pigment epithelium-derived factor inhibits adipogenesis in 3T3-L1 adipocytes and protects against high-fat diet-induced obesity and metabolic disorders in mice. Transl Res. 2019;: pubmed publisher
Chen X, Pan H, Li J, Zhang G, Cheng S, Zuo N, et al. Inhibition of myeloid differentiation 1 specifically in colon with antisense oligonucleotide exacerbates dextran sodium sulfate-induced colitis. J Cell Biochem. 2019;: pubmed publisher
Xu F, Hou B, Zhu X, Liu Y, Shi X, Li S, et al. Vaccaria n-Butanol Extract Lower the Production of Proinflammatory Cytokines and the Infection Risk of T. spiralis In Vivo. Acta Parasitol. 2019;: pubmed publisher
Guo H, Feng C, Zhang W, Luo Z, Zhang H, Zhang T, et al. Liver-target nanotechnology facilitates berberine to ameliorate cardio-metabolic diseases. Nat Commun. 2019;10:1981 pubmed publisher
Jia Y, Peng Y, Zhao Y, Cheng X, Zhou Y, Chai C, et al. Comparison of the Hepatoprotective Effects of the Three Main Stilbenes from Mulberry Twigs. J Agric Food Chem. 2019;: pubmed publisher
Meng G, Zhou X, Wang M, Zhou L, Wang Z, Wang M, et al. Gut microbe-derived metabolite trimethylamine N-oxide activates the cardiac autonomic nervous system and facilitates ischemia-induced ventricular arrhythmia via two different pathways. EBioMedicine. 2019;: pubmed publisher
Zhu Y, Meng Y, Zhao Y, Zhu J, Xu H, Zhang E, et al. Toxicological exploration of peptide-based cationic liposomes in siRNA delivery. Colloids Surf B Biointerfaces. 2019;179:66-76 pubmed publisher
Yang C, Lu M, Chen W, He Z, Hou X, Feng M, et al. Thyrotropin aggravates atherosclerosis by promoting macrophage inflammation in plaques. J Exp Med. 2019;216:1182-1198 pubmed publisher
He M, Huang X, Gao G, Zhou T, Li W, Hu J, et al. Olanzapine-induced endoplasmic reticulum stress and inflammation in the hypothalamus were inhibited by an ER stress inhibitor 4-phenylbutyrate. Psychoneuroendocrinology. 2019;104:286-299 pubmed publisher
Wei S, Huang J, Liu Z, Wang M, Zhang B, Lian Z, et al. Differential immune responses of C57BL/6 mice to infection by Salmonella enterica serovar Typhimurium strain SL1344, CVCC541 and CMCC50115. Virulence. 2019;10:248-259 pubmed publisher
Huang X, Wu B, Li J, Shang Y, Chen W, Nie X, et al. Anti-tumour effects of red blood cell membrane-camouflaged black phosphorous quantum dots combined with chemotherapy and anti-inflammatory therapy. Artif Cells Nanomed Biotechnol. 2019;47:968-979 pubmed publisher
Zhang T, Liu L, Lai W, Zeng Y, Xu H, Lan Q, et al. Interaction with tumor‑associated macrophages promotes PRL‑3‑induced invasion of colorectal cancer cells via MAPK pathway‑induced EMT and NF‑κB signaling‑induced angiogenesis. Oncol Rep. 2019;41:2790-2802 pubmed publisher
Yu Q, Wu L, Liu T, Li S, Feng J, Mao Y, et al. Protective effects of levo-tetrahydropalmatine on hepatic ischemia/reperfusion injury are mediated by inhibition of the ERK/NF-κB pathway. Int Immunopharmacol. 2019;70:435-445 pubmed publisher
Qu L, Zhu Y, Liu Y, Yang H, Zhu C, Ma P, et al. Protective effects of ginsenoside Rk3 against chronic alcohol-induced liver injury in mice through inhibition of inflammation, oxidative stress, and apoptosis. Food Chem Toxicol. 2019;126:277-284 pubmed publisher
Wang R, Dong Z, Lan X, Liao Z, Chen M. Sweroside Alleviated LPS-Induced Inflammation via SIRT1 Mediating NF-κB and FOXO1 Signaling Pathways in RAW264.7 Cells. Molecules. 2019;24: pubmed publisher
Li D, Cai Z, Wu J, Zhang Y. Bax inhibitor-1 overexpression in prelimbic cortex protects rats against depression-like behavior induced by olfactory bulbectomy and reduces apoptotic and inflammatory signals. Neurol Res. 2019;41:369-377 pubmed publisher
Yuan G, Xu L, Cai T, Hua B, Sun N, Yan Z, et al. Clock mutant promotes osteoarthritis by inhibiting the acetylation of NFκB. Osteoarthritis Cartilage. 2019;27:922-931 pubmed publisher
Zhang X, Yin Y, Yue L, Gong L. Selective Serotonin Reuptake Inhibitors Aggravate Depression-Associated Dry Eye Via Activating the NF-κB Pathway. Invest Ophthalmol Vis Sci. 2019;60:407-419 pubmed publisher
He Y, Xia Z, Yu D, Wang J, Jin L, Huang D, et al. Hepatoprotective effects and structure-activity relationship of five flavonoids against lipopolysaccharide/d-galactosamine induced acute liver failure in mice. Int Immunopharmacol. 2019;68:171-178 pubmed publisher
Xu B, Zang S, Li S, Guo J, Wang J, Wang D, et al. HMGB1-mediated differential response on hippocampal neurotransmitter disorder and neuroinflammation in adolescent male and female mice following cold exposure. Brain Behav Immun. 2019;76:223-235 pubmed publisher
Yuan C, Guo X, Zhou Q, Du F, Jiang W, Zhou X, et al. OAB-14, a bexarotene derivative, improves Alzheimer's disease-related pathologies and cognitive impairments by increasing β-amyloid clearance in APP/PS1 mice. Biochim Biophys Acta Mol Basis Dis. 2019;1865:161-180 pubmed publisher
Zhou L, Bi C, Gao L, An Y, Chen F, Chen F. Macrophage polarization in human gingival tissue in response to periodontal disease. Oral Dis. 2019;25:265-273 pubmed publisher
Sun R, Fan Y, Liang X, Gong T, Wang Q, Liu H, et al. Rapamycin and FTY720 Alleviate Atherosclerosis by Cross Talk of Macrophage Polarization and Autophagy. Biomed Res Int. 2018;2018:1010248 pubmed publisher
Yu Q, Liu T, Li S, Feng J, Wu L, Wang W, et al. The Protective Effects of Levo-Tetrahydropalmatine on ConA-Induced Liver Injury Are via TRAF6/JNK Signaling. Mediators Inflamm. 2018;2018:4032484 pubmed publisher
Mao J, Yi M, Wang R, Huang Y, Chen M. Protective Effects of Costunolide Against D-Galactosamine and Lipopolysaccharide-Induced Acute Liver Injury in Mice. Front Pharmacol. 2018;9:1469 pubmed publisher
Fan H, Yu X, Zou Z, Zheng W, Deng X, Guo L, et al. Metformin suppresses the esophageal carcinogenesis in rats treated with NMBzA through inhibiting AMPK/mTOR signaling pathway. Carcinogenesis. 2018;: pubmed publisher
Fan L, Xiao Q, Zhang L, Wang X, Huang Q, Li S, et al. CAPE-pNO2 attenuates diabetic cardiomyopathy through the NOX4/NF-κB pathway in STZ-induced diabetic mice. Biomed Pharmacother. 2018;108:1640-1650 pubmed publisher
Ishikawa Y, Iwata S, Hanami K, Nawata A, Zhang M, Yamagata K, et al. Relevance of interferon-gamma in pathogenesis of life-threatening rapidly progressive interstitial lung disease in patients with dermatomyositis. Arthritis Res Ther. 2018;20:240 pubmed publisher
Wang B, Zhang G, Yang M, Liu N, Li Y, Ma H, et al. Neuroprotective Effect of Anethole Against Neuropathic Pain Induced by Chronic Constriction Injury of the Sciatic Nerve in Mice. Neurochem Res. 2018;43:2404-2422 pubmed publisher
Wang D, Lao L, Pang X, Qiao Q, Pang L, Feng Z, et al. Asiatic acid from Potentilla chinensis alleviates non-alcoholic fatty liver by regulating endoplasmic reticulum stress and lipid metabolism. Int Immunopharmacol. 2018;65:256-267 pubmed publisher
Yuza K, Nagahashi M, Shimada Y, Nakano M, Tajima Y, Kameyama H, et al. Upregulation of phosphorylated sphingosine kinase 1 expression in colitis-associated cancer. J Surg Res. 2018;231:323-330 pubmed publisher
Liang A, Drazick A, Gao H, Li Y. Skeletal muscle secretion of IL-6 is muscle type specific: Ex vivo evidence. Biochem Biophys Res Commun. 2018;505:146-150 pubmed publisher
Liu Z, Liu F, Liu X, Ma C, Zhao J. Surgical incision induces learning impairment in mice partially through inhibition of the brain-derived neurotrophic factor signaling pathway in the hippocampus and amygdala. Mol Pain. 2018;14:1744806918805902 pubmed publisher
Guo K, Ma J, Liang W. Effects of SB202190 on expression levels of IL-6 and NF-κB in flap ischemia-reperfusion injury. Exp Ther Med. 2018;16:2522-2526 pubmed publisher
Zhou S, Wang X, Fan M, Li H, Bian F, Huang T, et al. Influence of vitamin D deficiency on T cell subsets and related indices during spinal tuberculosis. Exp Ther Med. 2018;16:718-722 pubmed publisher
Zhang X, Guo J, Wang H, Zhang C, Shi N, Cai W, et al. Underexpression of Receptor for Activated C Kinase 1 (RACK1) in Leukocytes from Patients with Severe Acute Pancreatitis. Tohoku J Exp Med. 2018;245:205-215 pubmed publisher
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product information
CatalogNo :
21865-1-AP
AntigenName :
IL-6
Package :
150UL
Price :
299 USD
Exsists20ul :
20ul trial size available
FullName :
interleukin 6 (interferon, beta 2)
Immunogen :
Fusion Protein
Species :
dog, goat, human, mouse, rat
Host :
Rabbit
IsConjugated :
Unconjugated
AntigenSpecies :
human
Application :
IHC, IF, ELISA
Clonlity :
Polyclonal
IsoType :
IgG
Synonyms :
B cell stimulatory factor 2, BSF 2, BSF2, CDF, CTL differentiation factor, HSF, Hybridoma growth factor, IL 6, IL6, IL-6, Interferon beta 2, Interleukin 6
PrimaryOrSecondary :
Primary
AntibodyBuffer :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
GenBankNo :
BC015511
Category :
Apoptosis;Binding Proteins;Cell Cycle;Cytoskeleton/Scaffold Proteins;Growth Factor/Cytokine/Hormone;Immunology;Membrane Proteins;Signal transduction;
PurifyMethod :
Antigen affinity purification
NewAb :
False
IsSellable :
True
Feature :
siRNA
AppTiter :
IHC 1:200 ;
company information
Proteintech Group
2201 W. Campbell Park Dr. STE12
Chicago, IL 60612
Proteintech@ptglab.com
https://www.ptglab.com
1-312-455-8498
headquarters: USA
At Proteintech, we produce every single antibody we sell; we do not rely on or supply to any other antibody providers: our products are unique and we are 100% accountable for each one. We realize this accountability by validating in-house, providing extensive technical support and guaranteeing your success: in addition to helping you troubleshoot your experiment, we will offer you a full cash refund if you are in any way dissatisfied. We can guarantee satisfaction because we have confidence in our products, confidence cultivated by the science behind our antibodies: we make them using as much of the native protein as possible, and purifying them using affinity purification with the original antigen. We carry out antibody production over a 102-day period, which allows for better antigen fitting to MHC molecules and affinity maturation in the host. This approach results in higher affinity antibodies with greater sensitivity, which you can use in any application and in multiple species.
You can only buy Proteintech antibodies directly from Proteintech or via one of its approved distributors — when you receive your antibody and see the Proteintech logo on the vial, know that you hold something that is truly unique.