This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Proteintech Group
product type :
antibody
product name :
GLUT1
catalog :
21829-1-AP
quantity :
150UL
price :
299 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section
citations: 78
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - paraffin section; human; 1:100; fig 3i
Feng J, Wu L, Ji J, Chen K, Yu Q, Zhang J, et al. PKM2 is the target of proanthocyanidin B2 during the inhibition of hepatocellular carcinoma. J Exp Clin Cancer Res. 2019;38:204 pubmed publisher
  • western blot; human; loading ...; fig 2b
Huang X, Gan G, Wang X, Xu T, Xie W. The HGF-MET axis coordinates liver cancer metabolism and autophagy for chemotherapeutic resistance. Autophagy. 2019;15:1258-1279 pubmed publisher
Hu Y, Deng K, Pan M, Liu S, Li W, Huang J, et al. Down-regulation of PCK2 inhibits the invasion and metastasis of laryngeal carcinoma cells. Am J Transl Res. 2020;12:3842-3857 pubmed
Yang S, Zhou F, Ma M, Yuan Y, Zhao S, Yu P. Neuronostatin Promotion Soluble Aβ1-42 Oligomers: Induced Dysfunctional Brain Glucose Metabolism in Mice. Neurochem Res. 2020;: pubmed publisher
Wang Y, Yang B, Lai Q, Shi J, Peng J, Zhang Y, et al. Reprogramming of m6A epitranscriptome is crucial for shaping of transcriptome and proteome in response to hypoxia. RNA Biol. 2020;:1-13 pubmed publisher
Yan X, Yang C, Hu W, Chen T, Wang Q, Pan F, et al. Knockdown of KRT17 decreases osteosarcoma cell proliferation and the Warburg effect via the AKT/mTOR/HIF1α pathway. Oncol Rep. 2020;44:103-114 pubmed publisher
Ndibalema A, Kabuye D, Wen S, Li L, Li X, Fan Q. Empagliflozin Protects Against Proximal Renal Tubular Cell Injury Induced by High Glucose via Regulation of Hypoxia-Inducible Factor 1-Alpha. Diabetes Metab Syndr Obes. 2020;13:1953-1967 pubmed publisher
Gao Z, Dlamini M, Ge H, Jiang L, Geng C, Li Q, et al. ATF4-mediated autophagy-dependent glycolysis plays an important role in attenuating apoptosis induced by Cr (VI) in A549 cells. Toxicol Lett. 2020;331:178-187 pubmed publisher
Wu Z, Jia J, Xu X, Xu M, Peng G, Ma J, et al. Human herpesvirus 6A promotes glycolysis in infected T cells by activation of mTOR signaling. PLoS Pathog. 2020;16:e1008568 pubmed publisher
Dong D, Dong Y, Fu J, Lu S, Yuan C, Xia M, et al. Bcl2 inhibitor ABT737 reverses the Warburg effect via the Sirt3-HIF1α axis to promote oxidative stress-induced apoptosis in ovarian cancer cells. Life Sci. 2020;255:117846 pubmed publisher
Wang Z, Yang Y, Hu S, He J, Wu Z, Qi Z, et al. Short-form RON (sf-RON) enhances glucose metabolism to promote cell proliferation via activating β-catenin/SIX1 signaling pathway in gastric cancer. Cell Biol Toxicol. 2020;: pubmed publisher
Nakano D, Kawaguchi T, Iwamoto H, Hayakawa M, Koga H, Torimura T. Effects of canagliflozin on growth and metabolic reprograming in hepatocellular carcinoma cells: Multi-omics analysis of metabolomics and absolute quantification proteomics (iMPAQT). PLoS ONE. 2020;15:e0232283 pubmed publisher
Zhang Q, Ma X, Dong M, Tan J, Zhang J, Zhuang L, et al. MiR-30b-5p regulates the lipid metabolism by targeting PPARGC1A in Huh-7 cell line. Lipids Health Dis. 2020;19:76 pubmed publisher
Ma L, Liu W, Xu A, Ji Q, Ma Y, Tai Y, et al. Activator of thyroid and retinoid receptor increases sorafenib resistance in hepatocellular carcinoma by facilitating the Warburg effect. Cancer Sci. 2020;111:2028-2040 pubmed publisher
Wu L, Zheng Q, Guo Y, Zhang K, Luo J, Xiao S, et al. Effect of Zhenxin Xingshui Yizhi Fang on Aβ25-35 induced expression of related transporters in HBMEC cell model. J Ethnopharmacol. 2020;260:112783 pubmed publisher
Chen L, Peng J, Wang Y, Jiang H, Wang W, Dai J, et al. Fenofibrate-induced mitochondrial dysfunction and metabolic reprogramming reversal: the anti-tumor effects in gastric carcinoma cells mediated by the PPAR pathway. Am J Transl Res. 2020;12:428-446 pubmed
Conroy L, Dougherty S, Kruer T, Metcalf S, Lorkiewicz P, He L, et al. Loss of Rb1 Enhances Glycolytic Metabolism in Kras-Driven Lung Tumors In Vivo. Cancers (Basel). 2020;12: pubmed publisher
Paul B, Tesfay L, Winkler C, Torti F, Torti S. Sideroflexin 4 affects Fe-S cluster biogenesis, iron metabolism, mitochondrial respiration and heme biosynthetic enzymes. Sci Rep. 2019;9:19634 pubmed publisher
Pan C, Liu Q, Wu X. HIF1α/miR-520a-3p/AKT1/mTOR Feedback Promotes The Proliferation And Glycolysis Of Gastric Cancer Cells. Cancer Manag Res. 2019;11:10145-10156 pubmed publisher
Chai Z, Yang Y, Gu Z, Cai X, Ye W, Kong L, et al. Recombinant Viral Capsid Protein L2 (rVL2) of HPV 16 Suppresses Cell Proliferation and Glucose Metabolism via ITGB7/C/EBPβ Signaling Pathway in Cervical Cancer Cell Lines. Onco Targets Ther. 2019;12:10415-10425 pubmed publisher
Chai X, Le Y, Wang J, Mei C, Feng J, Zhao H, et al. Carpesium abrotanoides (L.) Root as a Potential Source of Natural Anticancer Compounds: Targeting Glucose Metabolism and PKM2/HIF-1α Axis of Breast Cancer Cells. J Food Sci. 2019;84:3825-3832 pubmed publisher
Li Z, Liu J, Que L, Tang X. The immunoregulatory protein B7-H3 promotes aerobic glycolysis in oral squamous carcinoma via PI3K/Akt/mTOR pathway. J Cancer. 2019;10:5770-5784 pubmed publisher
Zhuang X, Chen Y, Wu Z, Xu Q, Chen M, Shao M, et al. Mitochondrial miR-181a-5p promotes glucose metabolism reprogramming in liver cancer by regulating the electron transport chain. Carcinogenesis. 2019;: pubmed publisher
Fujimoto B, Young M, Carter L, Pang A, Corley M, Fogelgren B, et al. The exocyst complex regulates insulin-stimulated glucose uptake of skeletal muscle cells. Am J Physiol Endocrinol Metab. 2019;317:E957-E972 pubmed publisher
Singh K, Hahm E, Alumkal J, Foley L, Hitchens T, Shiva S, et al. Reversal of the Warburg phenomenon in chemoprevention of prostate cancer by sulforaphane. Carcinogenesis. 2019;: pubmed publisher
Zhao H, Wu S, Li H, Duan Q, Zhang Z, Shen Q, et al. ROS/KRAS/AMPK Signaling Contributes to Gemcitabine-Induced Stem-like Cell Properties in Pancreatic Cancer. Mol Ther Oncolytics. 2019;14:299-312 pubmed publisher
Chen X, Li H, Yang Q, Lan X, Wang J, Cao Z, et al. Ginsenoside compound K ameliorates Alzheimer's disease in HT22 cells by adjusting energy metabolism. Mol Biol Rep. 2019;: pubmed publisher
Liu L, Shi Y, Shi J, Wang H, Sheng Y, Jiang Q, et al. The long non-coding RNA SNHG1 promotes glioma progression by competitively binding to miR-194 to regulate PHLDA1 expression. Cell Death Dis. 2019;10:463 pubmed publisher
Zhang W, Shao W, Dong Z, Zhang S, Liu C, Chen S. Cloxiquine, a traditional antituberculosis agent, suppresses the growth and metastasis of melanoma cells through activation of PPARγ. Cell Death Dis. 2019;10:404 pubmed publisher
Liu Y, Li Y, Huang Z, Wang Z, Nan L, Wang F, et al. The effect of intervertebral disc degenerative change on biological characteristics of nucleus pulposus mesenchymal stem cell: an in vitro study in rats. Connect Tissue Res. 2019;60:376-388 pubmed publisher
Yu W, Yang Z, Huang R, Min Z, Ye M. SIRT6 promotes the Warburg effect of papillary thyroid cancer cell BCPAP through reactive oxygen species. Onco Targets Ther. 2019;12:2861-2868 pubmed publisher
Peng W, Huang W, Ge X, Xue L, Zhao W, Xue J. Type Iγ phosphatidylinositol phosphate kinase promotes tumor growth by facilitating Warburg effect in colorectal cancer. EBioMedicine. 2019;: pubmed publisher
Wang W, Cheng Y, Yu P, Wang H, Zhang Y, Xu H, et al. Perfluorocarbon regulates the intratumoural environment to enhance hypoxia-based agent efficacy. Nat Commun. 2019;10:1580 pubmed publisher
Qin Y, Hu Q, Ji S, Xu J, Dai W, Liu W, et al. Homeodomain-interacting protein kinase 2 suppresses proliferation and aerobic glycolysis via ERK/cMyc axis in pancreatic cancer. Cell Prolif. 2019;52:e12603 pubmed publisher
Hu Q, Qin Y, Ji S, Xu W, Liu W, Sun Q, et al. UHRF1 promotes aerobic glycolysis and proliferation via suppression of SIRT4 in pancreatic cancer. Cancer Lett. 2019;452:226-236 pubmed publisher
Hu C, Tien S, Hsieh P, Jeng Y, Chang M, Chang Y, et al. High Glucose Triggers Nucleotide Imbalance through O-GlcNAcylation of Key Enzymes and Induces KRAS Mutation in Pancreatic Cells. Cell Metab. 2019;29:1334-1349.e10 pubmed publisher
Ma B, Cheng H, Mu C, Geng G, Zhao T, Luo Q, et al. The SIAH2-NRF1 axis spatially regulates tumor microenvironment remodeling for tumor progression. Nat Commun. 2019;10:1034 pubmed publisher
Cao D, Qi Z, Pang Y, Li H, Xie H, Wu J, et al. Retinoic Acid-Related Orphan Receptor C Regulates Proliferation, Glycolysis, and Chemoresistance via the PD-L1/ITGB6/STAT3 Signaling Axis in Bladder Cancer. Cancer Res. 2019;79:2604-2618 pubmed publisher
Chen R, Zhou X, Huang G, Liu J. Fructose 1,6-Bisphosphatase 1 Expression Reduces 18F-FDG Uptake in Clear Cell Renal Cell Carcinoma. Contrast Media Mol Imaging. 2019;2019:9463926 pubmed publisher
Jiang E, Xu Z, Wang M, Yan T, HUANG C, Zhou X, et al. Tumoral microvesicle-activated glycometabolic reprogramming in fibroblasts promotes the progression of oral squamous cell carcinoma. FASEB J. 2019;33:5690-5703 pubmed publisher
Yin F, Zhu Y, Zhang M, Yu H, Chen W, Qin J. A 3D human placenta-on-a-chip model to probe nanoparticle exposure at the placental barrier. Toxicol In Vitro. 2019;54:105-113 pubmed publisher
Zhu B, Cao X, Zhang W, Pan G, Yi Q, Zhong W, et al. MicroRNA-31-5p enhances the Warburg effect via targeting FIH. FASEB J. 2019;33:545-556 pubmed publisher
Jiang T, Zhou M, Fan J. Inhibition of GLUT-1 expression and the PI3K/Akt pathway to enhance the chemosensitivity of laryngeal carcinoma cells in vitro. Onco Targets Ther. 2018;11:7865-7872 pubmed publisher
Zhang X, Li Y, Ma Y, Yang L, Wang T, Meng X, et al. Yes-associated protein (YAP) binds to HIF-1α and sustains HIF-1α protein stability to promote hepatocellular carcinoma cell glycolysis under hypoxic stress. J Exp Clin Cancer Res. 2018;37:216 pubmed publisher
Wang Y, Li Q, Liu F, Jin S, Zhang Y, Zhang T, et al. Transcriptional activation of glucose transporter 1 in orthodontic tooth movement-associated mechanical response. Int J Oral Sci. 2018;10:27 pubmed publisher
Yang Y, Cao Y, Chen L, Liu F, Qi Z, Cheng X, et al. Cryptotanshinone suppresses cell proliferation and glucose metabolism via STAT3/SIRT3 signaling pathway in ovarian cancer cells. Cancer Med. 2018;7:4610-4618 pubmed publisher
Fan L, Huang C, Li J, Gao T, Lin Z, Yao T. Long non‑coding RNA urothelial cancer associated 1 regulates radioresistance via the hexokinase 2/glycolytic pathway in cervical cancer. Int J Mol Med. 2018;42:2247-2259 pubmed publisher
Yao J, Man S, Dong H, Yang L, Ma L, Gao W. Combinatorial treatment of Rhizoma Paridis saponins and sorafenib overcomes the intolerance of sorafenib. J Steroid Biochem Mol Biol. 2018;183:159-166 pubmed publisher
Li Q, Li Y, Liang L, Li J, Luo D, Liu Q, et al. Klotho negatively regulated aerobic glycolysis in colorectal cancer via ERK/HIF1α axis. Cell Commun Signal. 2018;16:26 pubmed publisher
Yan B, Cheng L, Jiang Z, Chen K, Zhou C, Sun L, et al. Resveratrol Inhibits ROS-Promoted Activation and Glycolysis of Pancreatic Stellate Cells via Suppression of miR-21. Oxid Med Cell Longev. 2018;2018:1346958 pubmed publisher
Li L, Liang Y, Kang L, Liu Y, Gao S, Chen S, et al. Transcriptional Regulation of the Warburg Effect in Cancer by SIX1. Cancer Cell. 2018;33:368-385.e7 pubmed publisher
Santasusagna S, Moreno I, Navarro A, Munoz C, Martinez F, Hernandez R, et al. miR-328 mediates a metabolic shift in colon cancer cells by targeting SLC2A1/GLUT1. Clin Transl Oncol. 2018;20:1161-1167 pubmed publisher
Wu Q, Chen X, Wang J, Sun P, Weng M, Chen W, et al. Nalmefene attenuates malignant potential in colorectal cancer cell via inhibition of opioid receptor. Acta Biochim Biophys Sin (Shanghai). 2018;50:156-163 pubmed publisher
Liu L, Li D, He Y, Zhou Y, Gong S, Wu L, et al. miR-210 protects renal cell against hypoxia-induced apoptosis by targeting HIF-1 alpha. Mol Med. 2017;23:258-271 pubmed publisher
Gu Z, Zhang H, Li Y, Shen S, Yin X, Zhang W, et al. CDC5L drives FAH expression to promote metabolic reprogramming in melanoma. Oncotarget. 2017;8:114328-114343 pubmed publisher
Li H, Li M, Pang Y, Liu F, Sheng D, Cheng X. Fructose?1,6?bisphosphatase?1 decrease may promote carcinogenesis and chemoresistance in cervical cancer. Mol Med Rep. 2017;16:8563-8571 pubmed publisher
Kwan S, King J, Yan J, Wang Z, Jiang X, Hutzler J, et al. Maternal Choline Supplementation Modulates Placental Nutrient Transport and Metabolism in Late Gestation of Mouse Pregnancy. J Nutr. 2017;147:2083-2092 pubmed publisher
Wei S, Fan Q, Yang L, Zhang X, Ma Y, Zong Z, et al. Promotion of glycolysis by HOTAIR through GLUT1 upregulation via mTOR signaling. Oncol Rep. 2017;38:1902-1908 pubmed publisher
Yao G, Yang J, Li X, Song X, Hayashi T, Tashiro S, et al. Blocking the utilization of glucose induces the switch from senescence to apoptosis in pseudolaric acid B-treated human lung cancer cells in vitro. Acta Pharmacol Sin. 2017;38:1401-1411 pubmed publisher
Wu D, Huang R, Hamanaka R, Krause M, Oh M, Kuo C, et al. HIF-1? is required for disturbed flow-induced metabolic reprogramming in human and porcine vascular endothelium. elife. 2017;6: pubmed publisher
Brownlow M, Jung S, Moore R, Bechmann N, Jankord R. Nutritional Ketosis Affects Metabolism and Behavior in Sprague-Dawley Rats in Both Control and Chronic Stress Environments. Front Mol Neurosci. 2017;10:129 pubmed publisher
Huang P, Zhao X, Xiao W, Dong Y, Hu G. 18F-fluorodeoxyglucose uptake predicts PKM2 expression in lung adenocarcinoma. Oncotarget. 2017;8:39618-39626 pubmed publisher
Cheng L, Jin Y, Liu M, Ruan M, Chen L. HER inhibitor promotes BRAF/MEK inhibitor-induced redifferentiation in papillary thyroid cancer harboring BRAFV600E. Oncotarget. 2017;8:19843-19854 pubmed publisher
Shen L, Zhao X, Zhou S, Lu Z, Zhao K, Fan J, et al. In vivo evaluation of the effects of simultaneous inhibition of GLUT-1 and HIF-1α by antisense oligodeoxynucleotides on the radiosensitivity of laryngeal carcinoma using micro 18F-FDG PET/CT. Oncotarget. 2017;8:34709-34726 pubmed publisher
Chen R, Li J, Zhou X, Liu J, Huang G. Fructose-1,6-Bisphosphatase 1 Reduces 18F FDG Uptake in Hepatocellular Carcinoma. Radiology. 2017;284:844-853 pubmed publisher
Liu W, Zhang B, Hu Q, Qin Y, Xu W, Shi S, et al. A new facet of NDRG1 in pancreatic ductal adenocarcinoma: Suppression of glycolytic metabolism. Int J Oncol. 2017;50:1792-1800 pubmed publisher
Zhong X, Tian S, Zhang X, Diao X, Dong F, Yang J, et al. CUE domain-containing protein 2 promotes the Warburg effect and tumorigenesis. EMBO Rep. 2017;18:809-825 pubmed publisher
Cai X, Ding H, Liu Y, Pan G, Li Q, Yang Z, et al. Expression of HMGB2 indicates worse survival of patients and is required for the maintenance of Warburg effect in pancreatic cancer. Acta Biochim Biophys Sin (Shanghai). 2017;49:119-127 pubmed publisher
Zhu W, Huang Y, Pan Q, Xiang P, Xie N, Yu H. MicroRNA-98 Suppress Warburg Effect by Targeting HK2 in Colon Cancer Cells. Dig Dis Sci. 2017;62:660-668 pubmed publisher
Liang C, Qin Y, Zhang B, Ji S, Shi S, Xu W, et al. ARF6, induced by mutant Kras, promotes proliferation and Warburg effect in pancreatic cancer. Cancer Lett. 2017;388:303-311 pubmed publisher
Shen C, Wei W, Qiu Z, Song H, Zhang X, Sun Z, et al. Metformin reduces glycometabolism of papillary thyroid carcinoma in vitro and in vivo. J Mol Endocrinol. 2017;58:15-23 pubmed
Xu H, Li Z, Yu Y, Sizdahkhani S, Ho W, Yin F, et al. A dynamic in vivo-like organotypic blood-brain barrier model to probe metastatic brain tumors. Sci Rep. 2016;6:36670 pubmed publisher
Wang S, Xie J, Li J, Liu F, Wu X, Wang Z. Cisplatin suppresses the growth and proliferation of breast and cervical cancer cell lines by inhibiting integrin ?5-mediated glycolysis. Am J Cancer Res. 2016;6:1108-17 pubmed
Wang J, Zhang P, Zhong J, Tan M, Ge J, Tao L, et al. The platelet isoform of phosphofructokinase contributes to metabolic reprogramming and maintains cell proliferation in clear cell renal cell carcinoma. Oncotarget. 2016;7:27142-57 pubmed publisher
Fang F, Gao Y, Wang T, Chen D, Liu J, Qian W, et al. Insulin signaling disruption in male mice due to perinatal bisphenol A exposure: Role of insulin signaling in the brain. Toxicol Lett. 2016;245:59-67 pubmed publisher
Luo J, Wu N, Jiang B, Wang L, Wang S, Li X, et al. Marine Bromophenol Derivative 3,4-Dibromo-5-(2-bromo-3,4-dihydroxy-6-isopropoxymethyl benzyl)benzene-1,2-diol Protects Hepatocytes from Lipid-Induced Cell Damage and Insulin Resistance via PTP1B Inhibition. Mar Drugs. 2015;13:4452-69 pubmed publisher
Teng C, Hsieh W, Wu H, Lin Y, Tsai H, Huang W, et al. Hepatitis B Virus Pre-S2 Mutant Induces Aerobic Glycolysis through Mammalian Target of Rapamycin Signal Cascade. PLoS ONE. 2015;10:e0122373 pubmed publisher
Fang F, Chen D, Yu P, Qian W, Zhou J, Liu J, et al. Effects of Bisphenol A on glucose homeostasis and brain insulin signaling pathways in male mice. Gen Comp Endocrinol. 2015;212:44-50 pubmed publisher
product information
CatalogNo :
21829-1-AP
AntigenName :
GLUT1
Package :
150UL
Price :
299 USD
Exsists20ul :
20ul trial size available
FullName :
solute carrier family 2 (facilitated glucose transporter), member 1
Immunogen :
Fusion Protein
Species :
human, mouse, rat
Host :
Rabbit
IsConjugated :
Unconjugated
AntigenSpecies :
human
Application :
WB, IHC, IF, FC, ELISA
Clonlity :
Polyclonal
IsoType :
IgG
Synonyms :
DYT17, DYT18, GLUT, GLUT 1, GLUT1, HepG2 glucose transporter, PED, SLC2A1
PrimaryOrSecondary :
Primary
AntibodyBuffer :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
GenBankNo :
BC121804
Category :
Binding Proteins;Membrane Proteins;Metabolism;Transport/Trafficking;
PurifyMethod :
Antigen affinity purification
NewAb :
False
IsSellable :
True
Feature :
siRNA
AppTiter :
FC 1:0 ; IF 1:50 ; IHC 1:1000 ; WB 1:800 ;
company information
Proteintech Group
2201 W. Campbell Park Dr. STE12
Chicago, IL 60612
Proteintech@ptglab.com
https://www.ptglab.com
1-312-455-8498
headquarters: USA
At Proteintech, we produce every single antibody we sell; we do not rely on or supply to any other antibody providers: our products are unique and we are 100% accountable for each one. We realize this accountability by validating in-house, providing extensive technical support and guaranteeing your success: in addition to helping you troubleshoot your experiment, we will offer you a full cash refund if you are in any way dissatisfied. We can guarantee satisfaction because we have confidence in our products, confidence cultivated by the science behind our antibodies: we make them using as much of the native protein as possible, and purifying them using affinity purification with the original antigen. We carry out antibody production over a 102-day period, which allows for better antigen fitting to MHC molecules and affinity maturation in the host. This approach results in higher affinity antibodies with greater sensitivity, which you can use in any application and in multiple species.
You can only buy Proteintech antibodies directly from Proteintech or via one of its approved distributors — when you receive your antibody and see the Proteintech logo on the vial, know that you hold something that is truly unique.