This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Proteintech Group
product type :
antibody
product name :
EZH2
catalog :
21800-1-AP
quantity :
150UL
price :
299 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, chromatin immunoprecipitation, RNA immunoprecipitation
citations: 29
Published Application/Species/Sample/DilutionReference
  • RNA immunoprecipitation; human; loading ...; fig 3f
  • immunocytochemistry; human; loading ...; fig 3g
  • immunohistochemistry; human; loading ...; fig 3e
  • western blot; human; fig 3b
Zhu P, Wang Y, Huang G, Ye B, Liu B, Wu J, et al. lnc-?-Catm elicits EZH2-dependent ?-catenin stabilization and sustains liver CSC self-renewal. Nat Struct Mol Biol. 2016;23:631-9 pubmed publisher
Huang H, Cai B, Suen C, Lee H, Hwang M, Liu F, et al. BGN/TLR4/NF-B Mediates Epigenetic Silencing of Immunosuppressive Siglec Ligands in Colon Cancer Cells. Cells. 2020;9: pubmed publisher
Yang R, Chen J, Zhang J, Qin R, Wang R, Qiu Y, et al. 1,25-Dihydroxyvitamin D protects against age-related osteoporosis by a novel VDR-Ezh2-p16 signal axis. Aging Cell. 2020;19:e13095 pubmed publisher
Li Y, Peng C, Fang C, Huang K. Upregulation of nuclear-enriched abundant transcript 1 confers oxaliplatin resistance to gastric cancer. Cell Biol Int. 2019;: pubmed publisher
Li T, Wang F, Dang Y, Dong J, Zhang Y, Zhang C, et al. P21 and P27 promote tumorigenesis and progression via cell cycle acceleration in seminal vesicles of TRAMP mice. Int J Biol Sci. 2019;15:2198-2210 pubmed publisher
Wang A, Dai H, Gong Y, Zhang C, Shu J, Luo Y, et al. ANLN-induced EZH2 upregulation promotes pancreatic cancer progression by mediating miR-218-5p/LASP1 signaling axis. J Exp Clin Cancer Res. 2019;38:347 pubmed publisher
Wang N, Zhang C, Wang W, Liu J, Yu Y, Li Y, et al. Long noncoding RNA DANCR regulates proliferation and migration by epigenetically silencing FBP1 in tumorigenesis of cholangiocarcinoma. Cell Death Dis. 2019;10:585 pubmed publisher
Cai Q, Niu H, Zhang B, Shi X, Liao M, Chen Z, et al. Effect of EZH2 knockdown on preimplantation development of porcine parthenogenetic embryos. Theriogenology. 2019;132:95-105 pubmed publisher
Yu G, Zhou H, Yao W, Meng L, Lang B. lncRNA TUG1 Promotes Cisplatin Resistance by Regulating CCND2 via Epigenetically Silencing miR-194-5p in Bladder Cancer. Mol Ther Nucleic Acids. 2019;16:257-271 pubmed publisher
Cao Z, Xue J, Cheng Y, Wang J, Liu Y, Li H, et al. MDM2 promotes genome instability by ubiquitinating the transcription factor HBP1. Oncogene. 2019;38:4835-4855 pubmed publisher
Huang H, Chao C, Wu P, Chung H, Lee H, Suen C, et al. Epigenetic silencing of the synthesis of immunosuppressive Siglec ligand glycans by NF-κB/EZH2/YY1 axis in early-stage colon cancers. Biochim Biophys Acta Gene Regul Mech. 2019;1862:173-183 pubmed publisher
Li D, Wang H, Huang X, Gu X, Xue W, Xu Y. Identification and Functional Characterization of a New Splicing Variant of EZH2 in the Central Nervous System. Int J Biol Sci. 2019;15:69-80 pubmed publisher
Huang Y, Zhang Z, Zhang M, Chen Y, Song J, Hou P, et al. CUL1 promotes breast cancer metastasis through regulating EZH2-induced the autocrine expression of the cytokines CXCL8 and IL11. Cell Death Dis. 2018;10:2 pubmed publisher
Yu Y, Zhang M, Liu J, Xu B, Yang J, Wang N, et al. Long Non-coding RNA PVT1 Promotes Cell Proliferation and Migration by Silencing ANGPTL4 Expression in Cholangiocarcinoma. Mol Ther Nucleic Acids. 2018;13:503-513 pubmed publisher
Zhao J, Xu J, Wang W, Zhao H, Liu H, Liu X, et al. Long non-coding RNA LINC-01572:28 inhibits granulosa cell growth via a decrease in p27 (Kip1) degradation in patients with polycystic ovary syndrome. EBioMedicine. 2018;36:526-538 pubmed publisher
Li Z, Qiu R, Qiu X, Tian T. SNHG6 Promotes Tumor Growth via Repression of P21 in Colorectal Cancer. Cell Physiol Biochem. 2018;49:463-478 pubmed publisher
Yu Y, Zhang M, Wang N, Li Q, Yang J, Yan S, et al. Epigenetic silencing of tumor suppressor gene CDKN1A by oncogenic long non-coding RNA SNHG1 in cholangiocarcinoma. Cell Death Dis. 2018;9:746 pubmed publisher
Wei C, Wang H, Xu F, Liu Z, Jiang R. LncRNA SOX21-AS1 is associated with progression of hepatocellular carcinoma and predicts prognosis through epigenetically silencing p21. Biomed Pharmacother. 2018;104:137-144 pubmed publisher
Morini M, Giampietro C, Corada M, Pisati F, Lavarone E, Cunha S, et al. VE-Cadherin-Mediated Epigenetic Regulation of Endothelial Gene Expression. Circ Res. 2018;122:231-245 pubmed publisher
Xu Y, Lian Y, Zhang Y, Huang S, Zuo Q, Yang N, et al. The long non-coding RNA PVT1 represses ANGPTL4 transcription through binding with EZH2 in trophoblast cell. J Cell Mol Med. 2018;22:1272-1282 pubmed publisher
Zhao H, Wang Z, Tang F, Zhao Y, Feng D, Li Y, et al. Carnosol-mediated Sirtuin 1 activation inhibits Enhancer of Zeste Homolog 2 to attenuate liver fibrosis. Pharmacol Res. 2018;128:327-337 pubmed publisher
Li M, Hong W, Hao C, Li L, Wu D, Shen A, et al. SIRT1 antagonizes liver fibrosis by blocking hepatic stellate cell activation in mice. FASEB J. 2018;32:500-511 pubmed publisher
Li B, Xie F, Zheng F, Jiang G, Zeng F, Xiao X. Overexpression of CircRNA BCRC4 regulates cell apoptosis and MicroRNA-101/EZH2 signaling in bladder cancer. J Huazhong Univ Sci Technolog Med Sci. 2017;37:886-890 pubmed publisher
Nie Y, Meng X, Liu J, Yan L, Wang P, Bi H, et al. Histone Modifications Regulate the Developmental Expression of Human Hepatic UDP-Glucuronosyltransferase 1A1. Drug Metab Dispos. 2017;45:1372-1378 pubmed publisher
Liu Y, Lai S, Ma W, Ke W, Zhang C, Liu S, et al. CDYL suppresses epileptogenesis in mice through repression of axonal Nav1.6 sodium channel expression. Nat Commun. 2017;8:355 pubmed publisher
Tan S, Ding K, Chong Q, Zhao J, Liu Y, Shao Y, et al. Post-transcriptional regulation of ERBB2 by miR26a/b and HuR confers resistance to tamoxifen in estrogen receptor-positive breast cancer cells. J Biol Chem. 2017;292:13551-13564 pubmed publisher
Huang Y, Tao T, Liu C, Guan H, Zhang G, Ling Z, et al. Upregulation of miR-146a by YY1 depletion correlates with delayed progression of prostate cancer. Int J Oncol. 2017;50:421-431 pubmed publisher
Li Y, Wang Z, Shi H, Li H, Li L, Fang R, et al. HBXIP and LSD1 Scaffolded by lncRNA Hotair Mediate Transcriptional Activation by c-Myc. Cancer Res. 2016;76:293-304 pubmed publisher
Cai D, Yuan M, Jia Y, Liu H, Hu Y, Zhao R. Maternal gestational betaine supplementation-mediated suppression of hepatic cyclin D2 and presenilin1 gene in newborn piglets is associated with epigenetic regulation of the STAT3-dependent pathway. J Nutr Biochem. 2015;26:1622-31 pubmed publisher
product information
CatalogNo :
21800-1-AP
AntigenName :
EZH2
Package :
150UL
Price :
299 USD
Exsists20ul :
20ul trial size available
FullName :
enhancer of zeste homolog 2 (Drosophila)
Immunogen :
Fusion Protein
Species :
human, mouse, pig, rat
Host :
Rabbit
IsConjugated :
Unconjugated
AntigenSpecies :
human
Application :
WB, IP, IF, chIP, ELISA
Clonlity :
Polyclonal
IsoType :
IgG
Synonyms :
Enhancer of zeste homolog 2, ENX 1, EZH1, EZH2, KMT6, Lysine N methyltransferase 6
PrimaryOrSecondary :
Primary
AntibodyBuffer :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
GenBankNo :
BC010858
Category :
Binding Proteins;Cytoskeleton/Scaffold Proteins;Metabolism;
PurifyMethod :
Antigen affinity purification
NewAb :
False
IsSellable :
True
Feature :
siRNA
AppTiter :
IF 1:50 ; IP 1:1500 ; WB 1:4000 ;
company information
Proteintech Group
2201 W. Campbell Park Dr. STE12
Chicago, IL 60612
Proteintech@ptglab.com
https://www.ptglab.com
1-312-455-8498
headquarters: USA
At Proteintech, we produce every single antibody we sell; we do not rely on or supply to any other antibody providers: our products are unique and we are 100% accountable for each one. We realize this accountability by validating in-house, providing extensive technical support and guaranteeing your success: in addition to helping you troubleshoot your experiment, we will offer you a full cash refund if you are in any way dissatisfied. We can guarantee satisfaction because we have confidence in our products, confidence cultivated by the science behind our antibodies: we make them using as much of the native protein as possible, and purifying them using affinity purification with the original antigen. We carry out antibody production over a 102-day period, which allows for better antigen fitting to MHC molecules and affinity maturation in the host. This approach results in higher affinity antibodies with greater sensitivity, which you can use in any application and in multiple species.
You can only buy Proteintech antibodies directly from Proteintech or via one of its approved distributors — when you receive your antibody and see the Proteintech logo on the vial, know that you hold something that is truly unique.